Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
194 phosphatases have substrate data;
--------------------------------
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
--------------------------------
299 KEGG pathways;
876 Reactome pathways;
--------------------------------
last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023
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HOXA10
Gene Name  | HOXA10 (QuickGO) | (A quick tutorial to explore the interctive visulaization) Representative structure: NA |
| Synonyms | HOXA10, HOX1H | |
| Protein Name | HOXA10 | |
| Alternative Name(s) | Homeobox protein Hox-A10;Homeobox protein Hox-1.8;Homeobox protein Hox-1H;PL; | |
| Protein Family | Belongs to the Abd-B homeobox family | |
| EntrezGene ID | 3206 (Comparitive Toxicogenomics) | |
| UniProt AC (Human) | P31260 (protein sequence) | |
| Enzyme Class | N/A | |
| Molecular Weight | 42414 Dalton | |
| Protein Length | 410 amino acids (AA) | |
| Genome Browsers | NCBI | ENSG00000253293 (Ensembl) | UCSC | |
| Crosslinking annotations | Query our ID-mapping table | |
| Orthologues | Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG0487 | eggNOG - ENOG4111FJP | |
| Phosphorylation Network | Visualize | |
| Domain organization, Expression, Diseases | (show / hide) |
| Protein Domain | InterPro | Pfam | SMART | 3D Structure | PDB | DrugPort | ModBase | SwissModel |
| Polypeptide organization (Pfam)  | |||
| Gene Expression | Gene Expression Atlas | Disease | OMIM | DisGeNet | ClinVar |
| Protein-protein interactions | STRING | IntAct | MINT | BioGRID | ||
| Phosphosites | Phospho.ELM | PhosphoSitePlus |
| Localization, Function, Catalytic activity and Sequence | (show / hide) |
| Localization (UniProt annotation) | |||
| Nucleus | |||
| Function (UniProt annotation) | |||
| Sequence-specific transcription factor which is part ofa developmental regulatory system that provides cells withspecific positional identities on the anterior-posterior axisBinds to the DNA sequence 5'-AA[AT]TTTTATTAC-3' | |||
| Catalytic Activity (UniProt annotation) | |||
| N/A | |||
| Protein Sequence | |||
| MSARKGYLLPSPNYPTTMSCSESPAANSFLVDSLISSGRGEAGGGGGGAGGGGGGGYYAHGGVYLPPAADLPYGLQSCGL FPTLGGKRNEAASPGSGGGGGGLGPGAHGYGPSPIDLWLDAPRSCRMEPPDGPPPPPQQQPPPPPQPPQPAPQATSCSFA QNIKEESSYCLYDSADKCPKVSATAAELAPFPRGPPPDGCALGTSSGVPVPGYFRLSQAYGTAKGYGSGGGGAQQLGAGP FPAQPPGRGFDLPPALASGSADAARKERALDSPPPPTLACGSGGGSQGDEEAHASSSAAEELSPAPSESSKASPEKDSLG NSKGENAANWLTAKSGRKKRCPYTKHQTLELEKEFLFNMYLTRERRLEISRSVHLTDRQVKIWFQNRRMKLKKMNRENRI RELTANFNFS | |||
| Motif information from Eukaryotic Linear Motif atlas (ELM) | (show / hide) |
| ELM Motif | Motif Instance
| Description | Motif Regex |
| NA | NA | NA | NA |
| Gene Ontology (P: Process; F: Function and C: Component terms) | (show / hide) | |
| GO:0000978 | F:RNA polymerase II proximal promoter sequence-specific DNA binding |
| GO:0000981 | F:RNA polymerase II transcription factor activity |
| GO:0001077 | sequence-specific DNA binding |
| GO:0001501 | F:transcriptional activator activity |
| GO:0005634 | RNA polymerase II proximal promoter sequence-specific DNA binding |
| GO:0005667 | P:skeletal system development |
| GO:0005737 | C:nucleus |
| GO:0007275 | C:transcription factor complex |
| GO:0007283 | C:cytoplasm |
| GO:0007338 | P:multicellular organism development |
| GO:0008584 | P:spermatogenesis |
| GO:0009952 | P:single fertilization |
| GO:0009954 | P:male gonad development |
| GO:0030326 | P:anterior/posterior pattern specification |
| GO:0042826 | P:proximal/distal pattern formation |
| GO:0045944 | P:embryonic limb morphogenesis |
| GO:0060065 | F:histone deacetylase binding |
