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INPP1
Localization (UniProt annotation) N/A Function (UniProt annotation) NA Catalytic Activity (UniProt annotation) 1D-myo-inositol 1,4-bisphosphate + H(2)O = 1D-myo-inositol 4-phosphate + phosphate Protein Sequence MSDILRELLCVSEKAANIARACRQQEALFQLLIEEKKEGEKNKKFAVDFKTLADVLVQEVIKQNMENKFPGLEKNIFGEE
SNEFTNDWGEKITLRLCSTEEETAELLSKVLNGNKVASEALARVVHQDVAFTDPTLDSTEINVPQDILGIWVDPIDSTYQ
YIKGSADIKSNQGIFPCGLQCVTILIGVYDIQTGVPLMGVINQPFVSRDPNTLRWKGQCYWGLSYMGTNMHSLQLTISRR
NGSETHTGNTGSEAAFSPSFSAVISTSEKETIKAALSRVCGDRIFGAAGAGYKSLCVVQGLVDIYIFSEDTTFKWDSCAA
HAILRAMGGGIVDLKECLERNPETGLDLPQLVYHVENEGAAGVDRWANKGGLIAYRSRKRLETFLSLLVQNLAPAETHT
ELM Motif Motif Instance Description Motif Regex NA NA NA NA
Pathway ID Pathway Name Pathway Description (KEGG) R-HSA-1855183 Synthesis of IP2, IP, and Ins in the cytosol. Inositol phosphates IP2, IP and the six-carbon cyclic alcohol inositol (Ins) are produced by various phosphatases and the inositol-3-phosphate synthase 1 (ISYNA1) (Ju et al. 2004, Ohnishi et al. 2007, Irvine & Schell 2001, Bunney & Katan 2010)
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Interacting partner Detection method Interaction type PubMed IDs Interaction Score Source C9orf16 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID DYNLL1 Two-hybrid, two hybrid physical, physical association 21900206 , (Europe PMC )0.37 BioGRID, IntAct, MINT LDOC1 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID MEOX2 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID NDC80 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID NECAB2 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID NR1D1 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID SYCE3 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID TLK1 Co-fractionation physical 22939629 , (Europe PMC )NA BioGRID USHBP1 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID WDR12 Co-fractionation physical 22939629 , (Europe PMC )NA BioGRID
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Interacting partner Detection method Interaction type PubMed IDs Interaction Score Source C9orf16 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID DYNLL1 Two-hybrid, two hybrid physical, physical association 21900206 , (Europe PMC )0.37 BioGRID, IntAct, MINT LDOC1 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID LIG1 two hybrid pooling approach physical association 16169070 , (Europe PMC )0.37 IntAct MEOX2 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID NDC80 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID NECAB2 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID NR1D1 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID SYCE3 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID TLK1 Co-fractionation physical 22939629 , (Europe PMC )NA BioGRID USHBP1 Two-hybrid physical 24722188 , (Europe PMC )NA BioGRID WDR12 Co-fractionation physical 22939629 , (Europe PMC )NA BioGRID