Collapse Statistics
226 human active and 11 inactive phosphatases in total;
194 phosphatases have substrate data;
305 protein substrates;
89 non-protein substrates;
1114 dephosphorylation interactions;
213 KEGG pathways;
206 NCI Nature PID pathways
560 Reactome pathways;
last update: 18 Feb, 2016


KEGG Pathway - Rheumatoid arthritis

Phosphatases known in this pathway

NameSynonymsUniProt ACDephosphorylate substrates:
ACP5 (QuickGO)TR-APP13686Arylsulfatase A mannose 6-phosphate glycoproteins

Substrates known in this pathway

NameSynonymsUniProt ACDephosphorylated by phosphatases:
c-JunTranscription factor AP-1 (Activator protein 1) (AP1) (Proto-oncogene c-Jun) (V-jun avian sarcoma virus 17 oncogene homolog) (p39)P05412PP2Balpha PP2Bbeta PP2Bgamma
TIE2Angiopoietin-1 receptor (EC (Tunica interna endothelial cell kinase) (Tyrosine-protein kinase receptor TEK) (Tyrosine-protein kinase receptor TIE-2) (hTIE2) (p140 TEK) (CD antigen CD202b)Q02763RPTPbeta

Sorry, no phosphatase/substrate known in this pathway here!