Collapse Statistics
226 human active and 11 inactive phosphatases in total;
194 phosphatases have substrate data;
305 protein substrates;
89 non-protein substrates;
1114 dephosphorylation interactions;
213 KEGG pathways;
206 NCI Nature PID pathways
560 Reactome pathways;
last update: 18 Feb, 2016


KEGG Pathway - Neuroactive ligand-receptor interaction

Phosphatases known in this pathway

Sorry, no phosphatase known in this pathway here! You may find potential phosphatases in this pathway through their substrates shown below.

Substrates known in this pathway

NameSynonymsUniProt ACDephosphorylated by phosphatases:
GRGlucocorticoid receptor (GR) (Nuclear receptor subfamily 3 group C member 1)P04150PP5
GHRGrowth hormone receptor (GH receptor) (Somatotropin receptor) [Cleaved into: Growth hormone-binding protein (GH-binding protein) (GHBP) (Serum-binding protein)]P10912PTP1B PTPH1
mGluR3Metabotropic glutamate receptor 3 (mGluR3)Q14832PP2Calpha
PAR-3Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)Q8TEW0PP1alpha
sphinganine 1-phosphate(2S,3R)-2-amino-3-hydroxyoctadecyl dihydrogen phosphate; Dihydrosphingosine 1-phosphate; dihydrosphingosine-1-phosphate; Sphinganine 1-phosphate; dihydro-S1PN/ASPP1 SPP2
sphingosine 1-phosphate(2S,3R,4E)-2-amino-4-octadecene-1,3-diol 1-(dihydrogen phosphate); Sphing-4-enine 1-phosphate; Sphingosine 1-phosphate; sphingosine-1-phosphate; S1PN/APAP2a PAP2b PAP2c SPP1 SPP2

Sorry, no phosphatase/substrate known in this pathway here!