Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
299 KEGG pathways;
876 Reactome pathways;
last update: 11 Mar, 2019




Gene Name SMO (QuickGO)
Interactive visualization of SMO structures
(A quick tutorial to explore the interctive visulaization)

Representative structure: 5L7I

SynonymsSMO, SMOH
Protein NameSMO
Alternative Name(s)
Smoothened homolog;SMO;Protein Gx;
Protein FamilyBelongs to the G-protein coupled receptor Fz/Smofamily
EntrezGene ID6608   (Comparitive Toxicogenomics)
UniProt AC (Human)Q99835 (protein sequence)
Enzyme ClassN/A
Molecular Weight86397 Dalton
Protein Length787 amino acids (AA)
Genome Browsers NCBI | ENSG00000128602 (Ensembl) | UCSC | 1000 Genomes
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree | eggNOG - KOG3577 | eggNOG - ENOG410XRC8
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)