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Collapse Statistics
226 human active and 11 inactive phosphatases in total;
194 phosphatases have substrate data;
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305 protein substrates;
89 non-protein substrates;
1114 dephosphorylation interactions;
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213 KEGG pathways;
206 NCI Nature PID pathways
560 Reactome pathways;
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last update: 18 Feb, 2016

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Reactome Pathway - Glycolysis

Phosphatases known in this pathway

NameSynonymsUniProt ACDephosphorylate substrates:
PFKFB2 (QuickGO)PFK/FBPase 2O60825beta-D-fructose 2,6-bisphosphate
PGAM2 (QuickGO)PGAM-MP152592,3-bisphospho-D-glycerate
PFKFB1 (QuickGO)PFK/FBPase 1P16118beta-D-fructose 2,6-bisphosphate
PGAM1 (QuickGO)PGAM-BP186692,3-bisphospho-D-glycerate
PPP2CB (QuickGO)PP2AbetaP62714alpha-crystallin A chain alpha-Syn AMPK1 ATM AXIN1 BAD BAX BCL2 BMPR-II c-Myc CAD CaMK IV CaMK-II subunit alpha CaMK-II subunit beta CaMKI-alpha CaMKI-beta CaMKIIgamma Carma1 Caspase-3 CDK1 CDK2 CDK5 activator 1, p35 CDK9 cGK1 CHK1 CHK2 CKI-epsilon CREB1 DARPP32 EF2 ELF1 ERK2 GAD65 GAD67 gamma-H2AX GM130 gp130 HD7 Histone H3.1 HSP27 IKKA IKKB Integrin beta-1 IPP-1 JNK1 Keratin-8 MAP kinase p38alpha MAPKAP kinase 2 MBP MDM2 MEK1 Mst1 Mst2 NFH NHERF1 p107 p130 p130cas p27Kip1 p53 P70S6K1 p90RSK1 p90RSK3 PACS1 PAK1 Paxillin PKA C-alpha PKB PKB gamma PKC-alpha PKC-beta PKC-delta PKC-lambda PKD PLK1 PP2A B subunit isoform B56-alpha RACGAP1 RAF1 RB Rhodopsin SEK1 SK1 SMAD1 SMAD3 SMO SRC TAK1 TAU TRAF2 Tubulin VASP Vimentin
PPP2CA (QuickGO)PP2AalphaP67775alpha-crystallin A chain alpha-Syn AMPK1 ATM AXIN1 BAD BAX BCL2 BMPR-II c-Myc CAD CaMK IV CaMK-II subunit alpha CaMK-II subunit beta CaMKI-alpha CaMKI-beta CaMKIIgamma Carma1 Caspase-3 CDK1 CDK2 CDK5 activator 1, p35 CDK9 cGK1 CHK1 CHK2 CKI-epsilon CREB1 DARPP32 EF2 ELF1 ERK2 GAD65 GAD67 gamma-H2AX GM130 gp130 HD7 Histone H3.1 HSP27 IKKA IKKB Integrin beta-1 IPP-1 JNK1 Keratin-8 MAP kinase p38alpha MAPKAP kinase 2 MBP MDM2 MEK1 Mst1 Mst2 NF-kappa-B p65 NFH NHERF1 p107 p130 p130cas p27Kip1 p53 P70S6K1 p90RSK1 p90RSK3 PACS1 PAK1 Paxillin PKA C-alpha PKB PKB gamma PKC-alpha PKC-beta PKC-delta PKC-lambda PKD PLK1 PP2A B subunit isoform B56-alpha RACGAP1 RAF1 RB Rhodopsin SEK1 SK1 SMAD1 SMAD3 SMO SRC TAK1 TAU TRAF2 Tubulin VASP Vimentin
PFKFB3 (QuickGO)PFK/FBPase 3Q16875beta-D-fructose 2,6-bisphosphate
PFKFB4 (QuickGO)PFK/FBPase 4Q16877beta-D-fructose 2,6-bisphosphate

Substrates known in this pathway

Sorry, no substrate known in this pathway here! You may find potential substrates in this pathway through their phosphatases shown above.

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