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Collapse Statistics
241 human active and 13 inactive phosphatases in total;
194 phosphatases have substrate data;
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336 protein substrates;
83 non-protein substrates;
1215 dephosphorylation interactions;
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299 KEGG pathways;
876 Reactome pathways;
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last scientific update:
11 Mar, 2019
last maintenance update:
01 Sep, 2023

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PHLPP1

Gene Name PHLPP1 (QuickGO)
Interactive visualization PHLPP1 structures
(A quick tutorial to explore the interctive visulaization)

Synonyms PHLPP1, KIAA0606, PHLPP, PLEKHE1, SCOP
Protein Name PHLPP1
Alternative Name(s)
PH domain leucine-rich repeat-containing protein phosphatase 1;3.1.3.16;Pleckstrin homology domain-containing family E member 1;PH domain-containing family E member 1;Suprachiasmatic nucleus circadian oscillatory protein;hSCOP;
EntrezGene ID23239   (Comparitive Toxicogenomics)
UniProt AC (Human) O60346 (protein sequence)
Enzyme ClassEC 3.1.3.16 (BRENDA )
Molecular Weight184672 Dalton
Protein Length1717 amino acids (AA)
Genome Browsers NCBI | ENSG00000081913 (Ensembl) | UCSC
Crosslinking annotations Query our ID-mapping table
Orthologues Quest For Orthologues (QFO) | GeneTree
Classification Superfamily: PPM | Historic class: PSTPs --> PP2C | CATH ID: 3.60.40.10 | SCOP Fold: PPM
Phosphatase activityactive | Catalytic signature motif: unknown
Phosphorylation Network Visualize
Domain organization, Expression, Diseases(show / hide)
Localization, Function, Catalytic activity and Sequence(show / hide)
Motif information from Eukaryotic Linear Motif atlas (ELM)(show / hide)
Gene Ontology (P: Process; F: Function and C: Component terms)(show / hide)

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