Collapse Statistics
226 human active and 11 inactive phosphatases in total;
194 phosphatases have substrate data;
305 protein substrates;
89 non-protein substrates;
1114 dephosphorylation interactions;
213 KEGG pathways;
206 NCI Nature PID pathways
560 Reactome pathways;
last update: 18 Feb, 2016

DEPOD - the human DEPhOsphorylation Database, is a manually curated database collecting human phosphatases, their experimentally verified substrates and dephosphorylation site information, and pathways in which they are involved. It also provides links to popular kinase databases and protein-protein interaction databases for these phosphatases and substrates.

Example: PTPN1 (gene name), PTP1B (protein name), P18031 (UniProt AC), ENSG00000196396 (Ensembl gene ID), 5770 (Entrez gene ID)

Browse human phosphatases Browse experimentally verified protein substrates of human phosphatases Browse experimentally verified non-protein substrates of human phosphatases Browse pathways involving human phosphatases and their substrates Browse human phosphatase-substrate network Download data in DEPOD Deposit your data to DEPOD

Please cite the following reference for this resource: Duan, G., Li, X., Köhn, M. (2015). The human DEPhOsphorylation database DEPOD: a 2015 update. Nucleic Acids Research, 43(Database issue):D531-5. (PMID: 25332398)

constructed and maintained by the laboratory of Maja Köhn

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