Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ANKRA2 Affinity Capture-MS physical 25752541 NA BioGRID ANKRD12 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct ANXA7 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT APLP1 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT APP Reconstituted Complex physical 21832049 NA BioGRID ARID4A Biochemical Activity physical 21148318 NA BioGRID ARRB2 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 17620599 0.35 BioGRID, IntAct ASPM Affinity Capture-MS, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical, physical association 17353931, 26496610 0.56 BioGRID, IntAct ATP5F1B Two-hybrid physical 21900206 NA BioGRID ATP5F1B two hybrid physical association 21900206 0.37 IntAct, MINT ATXN3 Affinity Capture-MS physical 29111377 NA BioGRID BAG6 Two-hybrid physical 16169070 NA BioGRID BAG6 anti bait coimmunoprecipitation, two hybrid pooling approach physical association 16169070, 17353931 0.57 IntAct BCL11A Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct BCL2 Negative Genetic genetic 28319113 NA BioGRID BIRC5 Affinity Capture-Western physical 10713676 NA BioGRID BRCA1 Biochemical Activity, Reconstituted Complex physical 12509456, 17334399, 9244350 NA BioGRID CAMK1 Biochemical Activity physical 23707388 NA BioGRID CAPNS1 Two-hybrid, two hybrid pooling approach physical, physical association 16169070 0.37 BioGRID, IntAct CCNA2 Affinity Capture-Western physical 24302728, 9716181 NA BioGRID CCND1 Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, Co-localization, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, barcode fusion genetics two hybrid, lexa b52 complementation, molecular sieving, protein array, protein kinase assay, proximity ligation assay, split luciferase complementation, two hybrid, two hybrid array, two hybrid bait and prey pooling approach, two hybrid prey pooling approach, validated two hybrid, x-ray crystallography association, direct interaction, phosphorylation reaction, physical, physical association 10580009, 10908655, 11160398, 11360184, 11463845, 12036906, 12519773, 15232106, 16985050, 17205132, 17420273, 18537972, 19237565, 19470470, 19767775, 20837141, 21242975, 23007395, 23707388, 23718855, 24218572, 24855949, 25241761, 25416956, 25910212, 26203195, 27107012, 27130439, 28514442, 29142209, 7568034, 8259215, 8662825, 8756624, 8867812, 8978686, 9106657, 9178893, 9228064, 9372967, 9837900 0.98 BioGRID, IntAct CCND2 Affinity Capture-MS, Affinity Capture-Western, anti bait coimmunoprecipitation, barcode fusion genetics two hybrid, split luciferase complementation, two hybrid, two hybrid array, two hybrid bait and prey pooling approach, two hybrid prey pooling approach, validated two hybrid physical, physical association 11360184, 11896535, 15169570, 17873913, 25910212, 26186194, 27107012, 28514442, 9178893, 0.86 BioGRID, IntAct CCND3 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, barcode fusion genetics two hybrid, light scattering, molecular sieving, protein array, split luciferase complementation, two hybrid, two hybrid array, two hybrid bait and prey pooling approach, two hybrid pooling approach, two hybrid prey pooling approach, validated two hybrid, x-ray crystallography association, direct interaction, physical, physical association 10342870, 11360184, 11896535, 14641107, 15232106, 16189514, 16782892, 16985050, 19237555, 21516116, 21988832, 23880157, 25416956, 25910212, 26186194, 26496610, 27107012, 28514442, 9106657, 9716181, 0.98 BioGRID, IntAct, MINT CCNE1 Affinity Capture-Western physical 9716181 NA BioGRID CDC37 Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, PCA, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, electron tomography, molecular sieving, tandem affinity purification, two hybrid association, physical, physical association 11867521, 17353931, 21675959, 21871133, 24189400, 25036637, 26186194, 27339980, 28514442, 8666233, 8703009, 9150368 0.89 BioGRID, IntAct CDC6 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct CDC7 Reconstituted Complex, protein array direct interaction, physical 15232106 0.44 BioGRID, IntAct CDK13 Affinity Capture-MS, anti tag coimmunoprecipitation, tandem affinity purification association, physical 23602568, 26496610 0.53 BioGRID, IntAct CDK5R1 Affinity Capture-Western physical 22654103 NA BioGRID CDK6 Affinity Capture-MS, tandem affinity purification association, physical 23455922 0.35 BioGRID, IntAct CDK7 protein kinase assay direct interaction 16327805 0.44 IntAct CDKN1A Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, protein array, pull down association, direct interaction, physical, physical association 11463845, 12383116, 15169570, 15232106, 15695403, 16962592, 17556661, 18850315, 20102411, 23007395, 23443559, 28514442, 8622677, 8756624, 9106657, 9464540, 9632134, 9658399 0.80 BioGRID, IntAct, MINT CDKN1B Affinity Capture-MS, Affinity Capture-Western, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, proximity ligation assay, tandem affinity purification association, physical, physical association 10198259, 10908655, 11360184, 11940657, 15695403, 16326706, 16782892, 17053782, 18285702, 18615582, 18850315, 19470470, 20837141, 21439954, 23602568, 23707388, 25241761, 26186194, 28514442, 8978686, 9106657, 9311993, 9464540, 9632134, 9658399 0.87 BioGRID, IntAct, MINT CDKN1C Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation physical, physical association 10713702, 9106657 0.40 BioGRID, IntAct CDKN2A Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, Reconstituted Complex, Two-hybrid physical 10491434, 10580009, 10585280, 10719365, 11556834, 11900540, 15065884, 15232106, 17353931, 17909018, 23455922, 23602568, 26186194, 26496610, 28042499, 28514442, 8259215, 8805225, 9228064, 9529249 NA BioGRID CDKN2A anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, confocal microscopy, protein array, pull down, tandem affinity purification association, colocalization, direct interaction, physical association 15232106, 17353931, 17517622, 17909018, 17955473, 23455922, 23602568, 24855949, 26496610 0.94 IntAct CDKN2B Affinity Capture-MS, Affinity Capture-Western, FRET, Two-hybrid, anti tag coimmunoprecipitation, bimolecular fluorescence complementation, split luciferase complementation, tandem affinity purification, two hybrid, two hybrid array, two hybrid bait and prey pooling approach, two hybrid pooling approach, two hybrid prey pooling approach, validated two hybrid association, physical, physical association 16169070, 16189514, 19447967, 21900206, 23455922, 23602568, 25910212, 26186194, 26496610, 28514442, 0.95 BioGRID, IntAct, MINT CDKN2C Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, barcode fusion genetics two hybrid, split luciferase complementation, tandem affinity purification, two hybrid array, two hybrid bait and prey pooling approach, two hybrid prey pooling approach, validated two hybrid association, physical, physical association 11900540, 17353931, 21988832, 23455922, 23602568, 25416956, 25910212, 26186194, 27107012, 28514442, 8001816, 0.96 BioGRID, IntAct CDKN2D Affinity Capture-MS, Affinity Capture-Western, Two-hybrid, barcode fusion genetics two hybrid, split luciferase complementation, tandem affinity purification, two hybrid, two hybrid array, two hybrid bait and prey pooling approach, two hybrid pooling approach, two hybrid prey pooling approach, validated two hybrid association, physical, physical association 16189514, 23602568, 23718855, 25416956, 25910212, 26186194, 27107012, 28514442, 0.93 BioGRID, IntAct CDT1 Affinity Capture-Western physical 15004027 NA BioGRID CEBPA Affinity Capture-Western, Co-fractionation, Reconstituted Complex physical 11684017, 11867521, 15107404 NA BioGRID CEP135 Proximity Label-MS, proximity-dependent biotin identification association, physical 26638075 0.35 BioGRID, IntAct CHEK2 Negative Genetic genetic 28319113 NA BioGRID CIB1 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct CNOT7 Affinity Capture-Western physical 10602502 NA BioGRID COPB2 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct COPS5 Affinity Capture-MS physical 21145461 NA BioGRID COPS6 Affinity Capture-MS physical 21145461 NA BioGRID CSTF3 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct CUL1 Affinity Capture-MS physical 21145461 NA BioGRID CUL3 Affinity Capture-MS physical 21145461 NA BioGRID CUL4B Affinity Capture-MS physical 21145461 NA BioGRID DAZAP2 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT DBNL Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 0.40 BioGRID, IntAct DDAH2 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT DNAJC9 Affinity Capture-MS, inference by socio-affinity scoring physical, physical association 27173435, 0.27 BioGRID, IntAct DUSP9 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct E2F4 Affinity Capture-MS, inference by socio-affinity scoring, tandem affinity purification physical, physical association 27173435, 0.53 BioGRID, IntAct EBI-1058650 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct EBI-1059072 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct EIF1AX Affinity Capture-MS physical 26186194 NA BioGRID ERBB2 Negative Genetic genetic 28319113 NA BioGRID FKBP5 Affinity Capture-Luminescence, Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25036637, 26186194, 28514442 0.35 BioGRID, IntAct FNIP1 Affinity Capture-Western physical 27353360 NA BioGRID FNIP2 Affinity Capture-Western physical 27353360 NA BioGRID FOXM1 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct GABARAPL1 anti tag coimmunoprecipitation association 20562859 0.35 IntAct GATA2 Affinity Capture-Western physical 17255359 NA BioGRID GEMIN4 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 0.40 BioGRID, IntAct GFER Affinity Capture-MS physical 26186194, 28514442 NA BioGRID GLI1 Affinity Capture-MS, Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256, 26603838 0.44 BioGRID, IntAct GUSB Affinity Capture-MS physical 26186194, 28514442 NA BioGRID H1F0 Biochemical Activity physical 12383116 NA BioGRID HDAC1 Negative Genetic genetic 28319113 NA BioGRID HIST1H1A Biochemical Activity physical 10447003, 11132966, 16878158, 9464540 NA BioGRID HIST1H1D Biochemical Activity physical 18850315 NA BioGRID HMGXB3 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT HOOK1 Two-hybrid, split luciferase complementation, two hybrid array, two hybrid bait and prey pooling approach, two hybrid prey pooling approach, validated two hybrid physical, physical association 25416956, 25910212, 0.81 BioGRID, IntAct HSP90AA1 Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, Co-fractionation, tandem affinity purification association, physical 11867521, 22315411, 22939624, 23455922, 26186194, 26804907, 28514442 0.35 BioGRID, IntAct HSP90AA5P Affinity Capture-MS physical 26186194, 28514442 NA BioGRID HSP90AB1 Affinity Capture-MS, anti tag coimmunoprecipitation, luminescence based mammalian interactome mapping, tandem affinity purification association, physical, physical association 22939624, 23455922, 26186194, 28514442 0.64 BioGRID, IntAct HSP90AB3P Affinity Capture-MS physical 26186194, 28514442 NA BioGRID HSP90AB4P Affinity Capture-MS physical 26186194, 28514442 NA BioGRID HSPA8 Affinity Capture-Western physical 18537972 NA BioGRID IL15RA Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct IQGAP1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct IRF8 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 21903422 0.35 BioGRID, IntAct JAK3 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID KAT2A anti bait coimmunoprecipitation physical association 24870244 0.40 IntAct KLHL32 Affinity Capture-MS physical 23718855 NA BioGRID KSR1 anti tag coimmunoprecipitation association 27086506 0.35 IntAct LIMK2 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 25852190 0.35 BioGRID, IntAct LNX2 barcode fusion genetics two hybrid, validated two hybrid physical association 27107012 0.49 IntAct LUC7L2 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT LYN Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 0.40 BioGRID, IntAct MAPRE2 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct MARCKS Biochemical Activity physical 10359664 NA BioGRID MCC anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct MCM2 Reconstituted Complex, protein array direct interaction, physical 15232106 0.44 BioGRID, IntAct MMS19 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct MTFP1 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct MTMR14 Affinity Capture-MS physical 27432908 NA BioGRID MTMR8 Affinity Capture-MS physical 27432908 NA BioGRID MYC Biochemical Activity, Two-hybrid, protein kinase assay, two hybrid array phosphorylation reaction, physical, physical association 21988832, 22094256 0.59 BioGRID, IntAct MYOD1 Reconstituted Complex, Two-hybrid physical 10022835, 10601020 NA BioGRID MZF1 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct NCOA2 Reconstituted Complex physical 12130539 NA BioGRID NOL12 two hybrid pooling approach physical association 16169070 0.37 IntAct NTRK1 Affinity Capture-MS physical 25921289 NA BioGRID NUP133 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct NUP155 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct OGFR Affinity Capture-MS physical 26186194, 28514442 NA BioGRID OGFRL1 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID OTX2 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct PCNA Affinity Capture-Western physical 11254741, 8101826, 8259215 NA BioGRID PGD Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct PKM Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT POLD1 Biochemical Activity physical 9545286 NA BioGRID PPP1CA Affinity Capture-Western, Co-fractionation, antibody array physical, physical association 17274640, 22939629 0.40 BioGRID, IntAct PPP1CC antibody array physical association 17274640 0.40 IntAct PPP2R1A Affinity Capture-Western, anti tag coimmunoprecipitation association, physical 17540176 0.35 BioGRID, IntAct PPP2R1B Affinity Capture-MS, Affinity Capture-Western, anti tag coimmunoprecipitation association, physical 17540176 0.35 BioGRID, IntAct PRKDC Negative Genetic genetic 28319113 NA BioGRID PRMT5 Affinity Capture-Western physical 20951943 NA BioGRID PSMA6 Affinity Capture-Western physical 22158041 NA BioGRID PSMD10 Protein-peptide, Reconstituted Complex, Two-hybrid physical 11900540 NA BioGRID PSMD9 Affinity Capture-Western physical 12684681 NA BioGRID PTEN Positive Genetic genetic 28319113 NA BioGRID PTMA Co-purification physical 11310559 NA BioGRID PTPN1 Affinity Capture-MS physical 27432908 NA BioGRID PTPN21 Affinity Capture-MS physical 27432908 NA BioGRID QARS Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT RB1 Affinity Capture-Western, Biochemical Activity physical 10198259, 10202152, 10486249, 11287611, 11306463, 11900540, 12190313, 12509456, 12519773, 12676926, 12949733, 15003538, 15147269, 15169570, 15241418, 15695403, 15922743, 15998794, 16205633, 16326706, 16878158, 16962592, 16985050, 17015477, 17053782, 17873913, 19225156, 19556892, 19767775, 22094256, 23543736, 8647086, 8756624, 8867812, 9003781, 9139732, 9190208, 9199321, 9464540 NA BioGRID RBL1 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct RBL2 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct RCAN3 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID RELA Affinity Capture-Western physical 25331947 NA BioGRID RFC1 Affinity Capture-Western physical 10353443 NA BioGRID RPL34 Reconstituted Complex physical 10049762 NA BioGRID RPRM Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 0.40 BioGRID, IntAct SAP25 Affinity Capture-MS physical 16449650 NA BioGRID SENP3 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct SERTAD1 Reconstituted Complex physical 10580009, 15065884 NA BioGRID SETDB1 Two-hybrid, two hybrid, two hybrid pooling approach physical, physical association 16169070, 21900206 0.55 BioGRID, IntAct, MINT SHOX2 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct SKP1 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct SLBP Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct SMAD2 Biochemical Activity physical 15241418 NA BioGRID SMAD3 Biochemical Activity, Co-localization, proximity ligation assay physical, physical association 15241418, 25241761 0.40 BioGRID, IntAct SMC1A Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 0.40 BioGRID, IntAct SMC3 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 0.40 BioGRID, IntAct SMTN Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct SNCA Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT SORBS1 Affinity Capture-MS physical 26496610 NA BioGRID SORBS1 anti tag coimmunoprecipitation association 26496610 0.35 IntAct SP1 Affinity Capture-Western physical 18769160 NA BioGRID TARDBP Affinity Capture-MS physical 20020773 NA BioGRID TK1 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT TMEM126A Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct TOP1 Negative Genetic genetic 28319113 NA BioGRID TRAP1 Affinity Capture-MS, tandem affinity purification association, physical 23455922 0.35 BioGRID, IntAct TRMT2A Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT TSC2 anti tag coimmunoprecipitation physical association 26977878 0.40 IntAct TSPYL2 Biochemical Activity physical 11395479 NA BioGRID UBTF Biochemical Activity physical 10202152 NA BioGRID UBXN1 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 0.40 BioGRID, IntAct UBXN10 Affinity Capture-MS physical 26389662 NA BioGRID UCHL1 Affinity Capture-Western physical 23543736 NA BioGRID UHRF2 Far Western, antibody array physical, physical association 21952639 0.40 BioGRID, IntAct USP17L2 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex physical 28067227 NA BioGRID VCP Affinity Capture-MS physical 23383273 NA BioGRID VHL Negative Genetic genetic 28319113 NA BioGRID VSIG8 Affinity Capture-MS physical 26186194 NA BioGRID VTA1 Two-hybrid, two hybrid pooling approach physical, physical association 16189514 0.37 BioGRID, IntAct VTN Affinity Capture-MS physical 28514442 NA BioGRID WDR33 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct WDR77 Affinity Capture-Western, anti bait coimmunoprecipitation association, physical 20951943 0.35 BioGRID, IntAct YBX3 Reconstituted Complex, Two-hybrid physical 10100871 NA BioGRID ZBTB16 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT ZC3H14 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct ZNF101 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct ZNF219 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct ZNF335 Biochemical Activity, protein kinase assay phosphorylation reaction, physical 22094256 0.44 BioGRID, IntAct ZNF655 coimmunoprecipitation, pull down, two hybrid array, two hybrid prey pooling approach physical association 15558030, 0.68 IntAct ZNFX1 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct