Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
NTRK1	8031	COSM48610,	lung	carcinoma	p.G368C	Substitution - Missense	1:156873884-156873884,	PATHOGENIC	0.99872	18948947
NTRK1	8031	COSM6919062,	lung	carcinoma	p.?	Unknown	1:156875009-156875009,	PATHOGENIC	0.99785	28481359
NTRK1	8031	COSM6912245,	skin	carcinoma	p.K447R	Substitution - Missense	1:156874994-156874994,	PATHOGENIC	0.99724	28481359
NTRK1	8031	COSM5773188,	kidney	carcinoma	p.A612T	Substitution - Missense	1:156879150-156879150,	PATHOGENIC	0.99667	28481359
NTRK1	8031	COSM5609666,	skin	malignant_melanoma	p.G605E	Substitution - Missense	1:156879130-156879130,	PATHOGENIC	0.99667	26343386
NTRK1	8031	COSM4990461,	skin	carcinoma	p.W693*	Substitution - Nonsense	1:156880031-156880031,	PATHOGENIC	0.99593	25589618
NTRK1	8031	COSM6925752,	urinary_tract	carcinoma	p.?	Unknown	1:156873632-156873632,	PATHOGENIC	0.99588	28481359
NTRK1	8031	COSM6847984,	pleura	mesothelioma	p.K441T	Substitution - Missense	1:156874976-156874976,	PATHOGENIC	0.99555	26928227
NTRK1	8031	COSM897437,	large_intestine	carcinoma	p.D738N	Substitution - Missense	1:156881463-156881463,	PATHOGENIC	0.99552	28481359
NTRK1	8031	COSM1600991,	prostate	carcinoma	p.R748Q	Substitution - Missense	1:156881494-156881494,	PATHOGENIC	0.99552	28481359
NTRK1	8031	COSM6966219,	large_intestine	carcinoma	p.G743E	Substitution - Missense	1:156881479-156881479,	PATHOGENIC	0.99552	28481359
NTRK1	8031	COSM897437,	large_intestine	carcinoma	p.D738N	Substitution - Missense	1:156881463-156881463,	PATHOGENIC	0.99552	28481359
NTRK1	8031	COSM6937201,	skin	carcinoma	p.G685D	Substitution - Missense	1:156880006-156880006,	PATHOGENIC	0.99548	28481359
NTRK1	8031	COSM48612,	lung	carcinoma	p.V422L	Substitution - Missense	1:156874918-156874918,	PATHOGENIC	0.99484	18948947
NTRK1	8031	COSM6921369,	NS	carcinoma	p.Y729H	Substitution - Missense	1:156880137-156880137,	PATHOGENIC	0.99465	28481359
NTRK1	8031	COSM5019975,	soft_tissue	haemangioblastoma	p.H604Y	Substitution - Missense	1:156879126-156879126,	PATHOGENIC	0.99447	25589003
NTRK1	8031	COSM5019975,	soft_tissue	haemangioblastoma	p.H604Y	Substitution - Missense	1:156879126-156879126,	PATHOGENIC	0.99447	25589003
NTRK1	8031	COSM6910084,	lung	carcinoma	p.D86V	Substitution - Missense	1:156864398-156864398,	PATHOGENIC	0.99322	28481359
NTRK1	8031	COSM272015,	skin	malignant_melanoma	p.R692C	Substitution - Missense	1:156880026-156880026,	PATHOGENIC	0.99314	28481359
NTRK1	8031	COSM6966951,	NS	malignant_melanoma	p.D793N	Substitution - Missense	1:156881628-156881628,	PATHOGENIC	0.99312	28481359
NTRK1	8031	COSM4990459,	skin	carcinoma	p.G357D	Substitution - Missense	1:156873852-156873852,	PATHOGENIC	0.99298	25589618
NTRK1	8031	COSM6973451,	upper_aerodigestive_tract	carcinoma	p.?	Unknown	1:156876212-156876212,	PATHOGENIC	0.99291	28481359
NTRK1	8031	COSM6925635,	endometrium	carcinoma	p.P478H	Substitution - Missense	1:156875598-156875598,	PATHOGENIC	0.99193	28481359
NTRK1	8031	COSM131783,	skin	malignant_melanoma	p.M379I	Substitution - Missense	1:156873919-156873919,	PATHOGENIC	0.99151	19718025
NTRK1	8031	COSM6982528,	lung	carcinoma	p.P309T	Substitution - Missense	1:156873707-156873707,	PATHOGENIC	0.99025	28481359
NTRK1	8031	COSM6945601,	pancreas	carcinoma	p.R507H	Substitution - Missense	1:156876098-156876098,	PATHOGENIC	0.98996	28481359
NTRK1	8031	COSM6986237,	skin	malignant_melanoma	p.G519D	Substitution - Missense	1:156876134-156876134,	PATHOGENIC	0.98996	28481359
NTRK1	8031	COSM6967818,	skin	carcinoma	p.E518K	Substitution - Missense	1:156876130-156876130,	PATHOGENIC	0.98996	28481359
NTRK1	8031	COSM6945601,	pancreas	carcinoma	p.R507H	Substitution - Missense	1:156876098-156876098,	PATHOGENIC	0.98996	28481359
NTRK1	8031	COSM6936884,	urinary_tract	carcinoma	p.W718C	Substitution - Missense	1:156880106-156880106,	PATHOGENIC	0.98895	28481359
NTRK1	8031	COSM6975137,	lung	carcinoma	p.R702L	Substitution - Missense	1:156880057-156880057,	PATHOGENIC	0.98895	28481359
NTRK1	8031	COSM6919190,	large_intestine	carcinoma	p.E492D	Substitution - Missense	1:156875641-156875641,	PATHOGENIC	0.98891	28481359
NTRK1	8031	COSM6928527,	lung	carcinoma	p.V455L	Substitution - Missense	1:156875528-156875528,	PATHOGENIC	0.98843	28481359
NTRK1	8031	COSM6951044,	skin	adnexal_tumour	p.G796S	Substitution - Missense	1:156881637-156881637,	PATHOGENIC	0.9882	28481359
NTRK1	8031	COSM6951044,	skin	malignant_melanoma	p.G796S	Substitution - Missense	1:156881637-156881637,	PATHOGENIC	0.9882	28481359
NTRK1	8031	COSM6977019,	large_intestine	carcinoma	p.L784P	Substitution - Missense	1:156881602-156881602,	PATHOGENIC	0.98766	28481359
NTRK1	8031	COSM6923118,	lung	carcinoma	p.D679Y	Substitution - Missense	1:156879351-156879351,	PATHOGENIC	0.98745	28481359
NTRK1	8031	COSM6730817,	large_intestine	carcinoma	p.E707K	Substitution - Missense	1:156880071-156880071,	PATHOGENIC	0.98722	28481359
NTRK1	8031	COSM6924986,	thyroid	carcinoma	p.V715M	Substitution - Missense	1:156880095-156880095,	PATHOGENIC	0.98722	28481359
NTRK1	8031	COSM6981287,	lung	carcinoma	p.G659C	Substitution - Missense	1:156879291-156879291,	PATHOGENIC	0.98721	28481359
NTRK1	8031	COSM6908794,	lung	carcinoma	p.V658L	Substitution - Missense	1:156879288-156879288,	PATHOGENIC	0.98721	28481359
NTRK1	8031	COSM6974424,	upper_aerodigestive_tract	carcinoma	p.Y359H	Substitution - Missense	1:156873857-156873857,	PATHOGENIC	0.98682	28481359
NTRK1	8031	COSM6918393,	skin	malignant_melanoma	p.?	Unknown	1:156874570-156874570,	PATHOGENIC	0.98607	28481359
NTRK1	8031	COSM6929813,	skin	malignant_melanoma	p.D668N	Substitution - Missense	1:156879318-156879318,	PATHOGENIC	0.98563	28481359
NTRK1	8031	COSM6929813,	skin	malignant_melanoma	p.D668N	Substitution - Missense	1:156879318-156879318,	PATHOGENIC	0.98563	28481359
NTRK1	8031	COSM6943442,	biliary_tract	carcinoma	p.A425V	Substitution - Missense	1:156874928-156874928,	PATHOGENIC	0.98557	28481359
NTRK1	8031	COSM6983923,	lung	carcinoma	p.E697D	Substitution - Missense	1:156880043-156880043,	PATHOGENIC	0.98547	28481359
NTRK1	8031	COSM6945534,	lung	carcinoma	p.A463S	Substitution - Missense	1:156875552-156875552,	PATHOGENIC	0.98544	28481359
NTRK1	8031	COSM6937588,	urinary_tract	carcinoma	p.R649Q	Substitution - Missense	1:156879262-156879262,	PATHOGENIC	0.98542	28481359
NTRK1	8031	COSM6922784,	NS	malignant_melanoma	p.G659S	Substitution - Missense	1:156879291-156879291,	PATHOGENIC	0.98542	28481359
NTRK1	8031	COSM529473,	endometrium	carcinoma	p.R654H	Substitution - Missense	1:156879277-156879277,	PATHOGENIC	0.9854	28481359
NTRK1	8031	COSM6936975,	meninges	meningioma	p.F468L	Substitution - Missense	1:156875569-156875569,	PATHOGENIC	0.98457	28481359
NTRK1	8031	COSM6967323,	skin	malignant_melanoma	p.A561V	Substitution - Missense	1:156876449-156876449,	PATHOGENIC	0.98384	28481359
NTRK1	8031	COSM6956836,	lung	carcinoma	p.R744H	Substitution - Missense	1:156881482-156881482,	PATHOGENIC	0.98321	28481359
NTRK1	8031	COSM6944985,	NS	carcinoma	p.E388K	Substitution - Missense	1:156873944-156873944,	PATHOGENIC	0.98297	28481359
NTRK1	8031	COSM6938279,	lung	carcinoma	p.A785T	Substitution - Missense	1:156881604-156881604,	PATHOGENIC	0.98285	28481359
NTRK1	8031	COSM6951329,	lung	carcinoma	p.L526H	Substitution - Missense	1:156876155-156876155,	PATHOGENIC	0.98274	28481359
NTRK1	8031	COSM6923910,	central_nervous_system	glioma	p.A527V	Substitution - Missense	1:156876158-156876158,	PATHOGENIC	0.98178	28481359
NTRK1	8031	COSM4023451,	pancreas	carcinoma	p.P311L	Substitution - Missense	1:156873714-156873714,	PATHOGENIC	0.98161	28481359
NTRK1	8031	COSM4023451,	large_intestine	carcinoma	p.P311L	Substitution - Missense	1:156873714-156873714,	PATHOGENIC	0.98161	28481359
NTRK1	8031	COSM6974029,	lung	carcinoma	p.L322I	Substitution - Missense	1:156873746-156873746,	PATHOGENIC	0.98054	28481359
NTRK1	8031	COSM6946076,	large_intestine	carcinoma	p.H648N	Substitution - Missense	1:156879258-156879258,	PATHOGENIC	0.97922	28481359
NTRK1	8031	COSM6950003,	large_intestine	carcinoma	p.A642V	Substitution - Missense	1:156879241-156879241,	PATHOGENIC	0.97324	28481359
NTRK1	8031	COSM6944193,	pancreas	carcinoma	p.V578I	Substitution - Missense	1:156876499-156876499,	PATHOGENIC	0.97306	28481359
NTRK1	8031	COSM3475491,	skin	malignant_melanoma	p.T340I	Substitution - Missense	1:156873801-156873801,	PATHOGENIC	0.96943	28481359
NTRK1	8031	COSM6974364,	skin	carcinoma	p.K725E	Substitution - Missense	1:156880125-156880125,	PATHOGENIC	0.96931	28481359
NTRK1	8031	COSM6985307,	NS	carcinoma	p.M469I	Substitution - Missense	1:156875572-156875572,	PATHOGENIC	0.96582	28481359
NTRK1	8031	COSM6967068,	endometrium	carcinoma	p.V511M	Substitution - Missense	1:156876109-156876109,	PATHOGENIC	0.96379	28481359
NTRK1	8031	COSM6967068,	urinary_tract	carcinoma	p.V511M	Substitution - Missense	1:156876109-156876109,	PATHOGENIC	0.96379	28481359
NTRK1	8031	COSM313390,	lung	carcinoma	p.E324D	Substitution - Missense	1:156873754-156873754,	PATHOGENIC	0.95891	22941188
NTRK1	8031	COSM6951042,	skin	adnexal_tumour	p.L432F	Substitution - Missense	1:156874948-156874948,	PATHOGENIC	0.95798	28481359
NTRK1	8031	COSM6058578,	NS	carcinoma	p.L644M	Substitution - Missense	1:156879246-156879246,	PATHOGENIC	0.95214	28481359
NTRK1	8031	COSM5020487,	soft_tissue	haemangioblastoma	p.E581K	Substitution - Missense	1:156876508-156876508,	PATHOGENIC	0.95087	25589003
NTRK1	8031	COSM6983548,	liver	carcinoma	p.L456Q	Substitution - Missense	1:156875532-156875532,	PATHOGENIC	0.95043	28481359
NTRK1	8031	COSM6911491,	lung	carcinoma	p.Q770*	Substitution - Nonsense	1:156881559-156881559,	PATHOGENIC	0.9481	28481359
NTRK1	8031	COSM6980867,	lung	carcinoma	p.N259K	Substitution - Missense	1:156871682-156871682,	PATHOGENIC	0.94711	28481359
NTRK1	8031	COSM1259640,	endometrium	carcinoma	p.E413K	Substitution - Missense	1:156874612-156874612,	PATHOGENIC	0.94632	28481359
NTRK1	8031	COSM1259640,	large_intestine	carcinoma	p.E413K	Substitution - Missense	1:156874612-156874612,	PATHOGENIC	0.94632	28481359
NTRK1	8031	COSM6967279,	lung	carcinoma	p.M539I	Substitution - Missense	1:156876195-156876195,	PATHOGENIC	0.94573	28481359
NTRK1	8031	COSM6986524,	lung	carcinoma	p.?	Unknown	1:156868250-156868250,	PATHOGENIC	0.94547	28481359
NTRK1	8031	COSM6918188,	large_intestine	carcinoma	p.T360M	Substitution - Missense	1:156873861-156873861,	PATHOGENIC	0.94446	28481359
NTRK1	8031	COSM3750441,	soft_tissue	haemangioblastoma	p.G613V	Substitution - Missense	1:156879154-156879154,	PATHOGENIC	0.94336	25589003
NTRK1	8031	COSM3750441,	soft_tissue	haemangioblastoma	p.G613V	Substitution - Missense	1:156879154-156879154,	PATHOGENIC	0.94336	25589003
NTRK1	8031	COSM20674,	ovary	carcinoma	p.A107V	Substitution - Missense	1:156864760-156864760,	PATHOGENIC	0.93606	Info_not_available
NTRK1	8031	COSM20674,	ovary	carcinoma	p.A107V	Substitution - Missense	1:156864760-156864760,	PATHOGENIC	0.93606	Info_not_available
NTRK1	8031	COSM20674,	soft_tissue	epithelioid_sarcoma	p.A107V	Substitution - Missense	1:156864760-156864760,	PATHOGENIC	0.93606	28481359
NTRK1	8031	COSM20674,	large_intestine	carcinoma	p.A107V	Substitution - Missense	1:156864760-156864760,	PATHOGENIC	0.93606	28481359
NTRK1	8031	COSM20674,	large_intestine	carcinoma	p.A107V	Substitution - Missense	1:156864760-156864760,	PATHOGENIC	0.93606	28481359
NTRK1	8031	COSM6913750,	skin	carcinoma	p.W158*	Substitution - Nonsense	1:156868149-156868149,	PATHOGENIC	0.93532	28481359
NTRK1	8031	COSM6950368,	lung	carcinoma	p.S433Y	Substitution - Missense	1:156874952-156874952,	PATHOGENIC	0.93133	28481359
NTRK1	8031	COSM6929853,	lung	carcinoma	p.K703T	Substitution - Missense	1:156880060-156880060,	PATHOGENIC	0.92909	28481359
NTRK1	8031	COSM6931320,	skin	malignant_melanoma	p.D389N	Substitution - Missense	1:156873947-156873947,	PATHOGENIC	0.92801	28481359
NTRK1	8031	COSM6917740,	urinary_tract	carcinoma	p.S484C	Substitution - Missense	1:156875616-156875616,	PATHOGENIC	0.92788	28481359
NTRK1	8031	COSM6928022,	lung	carcinoma	p.N318Y	Substitution - Missense	1:156873734-156873734,	PATHOGENIC	0.92302	28481359
NTRK1	8031	COSM6948894,	endometrium	carcinoma	p.L466M	Substitution - Missense	1:156875561-156875561,	PATHOGENIC	0.917	28481359
NTRK1	8031	COSM6961625,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.V207M	Substitution - Missense	1:156868549-156868549,	PATHOGENIC	0.91369	28481359
NTRK1	8031	COSM6952097,	large_intestine	carcinoma	p.E275K	Substitution - Missense	1:156871728-156871728,	PATHOGENIC	0.91344	28481359
NTRK1	8031	COSM5609664,	skin	malignant_melanoma	p.A457T	Substitution - Missense	1:156875534-156875534,	PATHOGENIC	0.90835	26343386
NTRK1	8031	COSM6962059,	skin	malignant_melanoma	p.L175R	Substitution - Missense	1:156868199-156868199,	PATHOGENIC	0.90505	28481359
NTRK1	8031	COSM6923434,	central_nervous_system	glioma	p.R602*	Substitution - Nonsense	1:156876571-156876571,	PATHOGENIC	0.90051	28481359
NTRK1	8031	COSM1984596,	skin	malignant_melanoma	p.P149L	Substitution - Missense	1:156868121-156868121,	PATHOGENIC	0.89955	28481359
NTRK1	8031	COSM6957010,	lung	carcinoma	p.R583L	Substitution - Missense	1:156876515-156876515,	PATHOGENIC	0.89926	28481359
NTRK1	8031	COSM6933818,	lung	carcinoma	p.C501W	Substitution - Missense	1:156876081-156876081,	PATHOGENIC	0.88815	28481359
NTRK1	8031	COSM4956619,	kidney	carcinoma	p.G643D	Substitution - Missense	1:156879244-156879244,	PATHOGENIC	0.88726	28481359
NTRK1	8031	COSM4468996,	skin	carcinoma	p.F525F	Substitution - coding silent	1:156876153-156876153,	PATHOGENIC	0.88639	25589618
NTRK1	8031	COSM6924640,	lung	carcinoma	p.S153Y	Substitution - Missense	1:156868133-156868133,	PATHOGENIC	0.88367	28481359
NTRK1	8031	COSM6935155,	endometrium	carcinoma	p.A553D	Substitution - Missense	1:156876425-156876425,	PATHOGENIC	0.88328	28481359
NTRK1	8031	COSM6937586,	urinary_tract	carcinoma	p.Q350R	Substitution - Missense	1:156873831-156873831,	PATHOGENIC	0.88327	28481359
NTRK1	8031	COSM6912247,	skin	carcinoma	p.P584L	Substitution - Missense	1:156876518-156876518,	PATHOGENIC	0.88007	28481359
NTRK1	8031	COSM6922293,	lung	carcinoma	p.Q173L	Substitution - Missense	1:156868193-156868193,	PATHOGENIC	0.8648	28481359
NTRK1	8031	COSM1984606,	large_intestine	carcinoma	p.V282I	Substitution - Missense	1:156871749-156871749,	PATHOGENIC	0.85825	28481359
NTRK1	8031	COSM6979984,	large_intestine	carcinoma	p.G472C	Substitution - Missense	1:156875579-156875579,	PATHOGENIC	0.85463	28481359
NTRK1	8031	COSM6976181,	lung	carcinoma	p.G208W	Substitution - Missense	1:156868552-156868552,	PATHOGENIC	0.85393	28481359
NTRK1	8031	COSM6970407,	skin	malignant_melanoma	p.R583C	Substitution - Missense	1:156876514-156876514,	PATHOGENIC	0.85084	28481359
NTRK1	8031	COSM6966241,	lung	carcinoma	p.G44C	Substitution - Missense	1:156861064-156861064,	PATHOGENIC	0.84946	28481359
NTRK1	8031	COSM6946969,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.S283F	Substitution - Missense	1:156871753-156871753,	PATHOGENIC	0.84732	28481359
NTRK1	8031	COSM6923140,	ovary	carcinoma	p.G192A	Substitution - Missense	1:156868505-156868505,	PATHOGENIC	0.84117	28481359
NTRK1	8031	COSM3750439,	soft_tissue	haemangioblastoma	p.Q558Q	Substitution - coding silent	1:156876441-156876441,	PATHOGENIC	0.83993	25589003
NTRK1	8031	COSM3750439,	soft_tissue	haemangioblastoma	p.Q558Q	Substitution - coding silent	1:156876441-156876441,	PATHOGENIC	0.83993	25589003
NTRK1	8031	COSM3750439,	soft_tissue	haemangioblastoma	p.Q558Q	Substitution - coding silent	1:156876441-156876441,	PATHOGENIC	0.83993	25589003
NTRK1	8031	COSM3750439,	soft_tissue	haemangioblastoma	p.Q558Q	Substitution - coding silent	1:156876441-156876441,	PATHOGENIC	0.83993	25589003
NTRK1	8031	COSM3750439,	soft_tissue	haemangioblastoma	p.Q558Q	Substitution - coding silent	1:156876441-156876441,	PATHOGENIC	0.83993	25589003
NTRK1	8031	COSM3750439,	soft_tissue	haemangioblastoma	p.Q558Q	Substitution - coding silent	1:156876441-156876441,	PATHOGENIC	0.83993	25589003
NTRK1	8031	COSM3750439,	soft_tissue	haemangioblastoma	p.Q558Q	Substitution - coding silent	1:156876441-156876441,	PATHOGENIC	0.83993	25589003
NTRK1	8031	COSM6965719,	lung	carcinoma	p.G192V	Substitution - Missense	1:156868505-156868505,	PATHOGENIC	0.83586	28481359
NTRK1	8031	COSM6944023,	urinary_tract	carcinoma	p.Q141H	Substitution - Missense	1:156866973-156866973,	PATHOGENIC	0.83396	28481359
NTRK1	8031	COSM6951032,	upper_aerodigestive_tract	carcinoma	p.Q570*	Substitution - Nonsense	1:156876475-156876475,	PATHOGENIC	0.83346	28481359
NTRK1	8031	COSM6963125,	skin	malignant_melanoma	p.S153F	Substitution - Missense	1:156868133-156868133,	PATHOGENIC	0.83037	28481359
NTRK1	8031	COSM6730803,	large_intestine	carcinoma	p.R583H	Substitution - Missense	1:156876515-156876515,	PATHOGENIC	0.82957	28481359
NTRK1	8031	COSM6730803,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R583H	Substitution - Missense	1:156876515-156876515,	PATHOGENIC	0.82957	28481359
NTRK1	8031	COSM124876,	large_intestine	carcinoma	p.R593W	Substitution - Missense	1:156876544-156876544,	PATHOGENIC	0.829	28481359
NTRK1	8031	COSM6730805,	urinary_tract	carcinoma	p.R599C	Substitution - Missense	1:156876562-156876562,	PATHOGENIC	0.82558	28481359
NTRK1	8031	COSM6730799,	skin	adnexal_tumour	p.R682C	Substitution - Missense	1:156879360-156879360,	PATHOGENIC	0.82457	28481359
NTRK1	8031	COSM6922969,	large_intestine	carcinoma	p.R686C	Substitution - Missense	1:156880008-156880008,	PATHOGENIC	0.82432	28481359
NTRK1	8031	COSM96085,	lung	carcinoma	p.V543V	Substitution - coding silent	1:156876207-156876207,	PATHOGENIC	0.81368	20668451
NTRK1	8031	COSM6915425,	NS	carcinoma	p.L526F	Substitution - Missense	1:156876154-156876154,	PATHOGENIC	0.79409	28481359
NTRK1	8031	COSM6973449,	upper_aerodigestive_tract	carcinoma	p.E275D	Substitution - Missense	1:156871730-156871730,	PATHOGENIC	0.78073	28481359
NTRK1	8031	COSM6931037,	large_intestine	carcinoma	p.V144A	Substitution - Missense	1:156868106-156868106,	PATHOGENIC	0.74999	28481359
NTRK1	8031	COSM6948960,	large_intestine	carcinoma	p.V135M	Substitution - Missense	1:156866953-156866953,	PATHOGENIC	0.7495	28481359
NTRK1	8031	COSM131785,	skin	malignant_melanoma	p.R583G	Substitution - Missense	1:156876514-156876514,	PATHOGENIC	0.73391	19718025
NTRK1	8031	COSM6976271,	NS	malignant_melanoma	p.Q487*	Substitution - Nonsense	1:156875624-156875624,	PATHOGENIC	0.71383	28481359
NTRK1	8031	COSM6949518,	thyroid	carcinoma	p.S256N	Substitution - Missense	1:156871672-156871672,	PATHOGENIC	0.71273	28481359
NTRK1	8031	COSM6942754,	large_intestine	carcinoma	p.E384K	Substitution - Missense	1:156873932-156873932,	PATHOGENIC	0.70554	28481359
NTRK1	8031	COSM6942754,	breast	carcinoma	p.E384K	Substitution - Missense	1:156873932-156873932,	PATHOGENIC	0.70554	28481359
NTRK1	8031	COSM6929354,	NS	malignant_melanoma	p.D209N	Substitution - Missense	1:156868555-156868555,	PATHOGENIC	0.70193	28481359
NTRK1	8031	COSM5609668,	skin	malignant_melanoma	p.I98I	Substitution - coding silent	1:156864734-156864734,	PATHOGENIC	0.70062	26343386
NTRK1	8031	COSM6985306,	NS	carcinoma	p.G32C	Substitution - Missense	1:156861028-156861028,	NEUTRAL	0.47258	28481359
NTRK1	8031	COSM5762903,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G18E	Substitution - Missense	1:156860987-156860987,	NEUTRAL	0.44207	27127180
NTRK1	8031	COSM5762903,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G18E	Substitution - Missense	1:156860987-156860987,	NEUTRAL	0.44207	27127180
NTRK1	8031	COSM5977744,	central_nervous_system	glioma	p.R686H	Substitution - Missense	1:156880009-156880009,	NEUTRAL	0.43908	26487540
NTRK1	8031	COSM5977744,	prostate	carcinoma	p.R686H	Substitution - Missense	1:156880009-156880009,	NEUTRAL	0.43908	28481359
NTRK1	8031	COSM5977744,	prostate	carcinoma	p.R686H	Substitution - Missense	1:156880009-156880009,	NEUTRAL	0.43908	28481359
NTRK1	8031	COSM48609,	lung	carcinoma	p.S326R	Substitution - Missense	1:156873760-156873760,	NEUTRAL	0.41045	18948947
NTRK1	8031	COSM1984604,	skin	malignant_melanoma	p.S277F	Substitution - Missense	1:156871735-156871735,	NEUTRAL	0.38183	28481359
NTRK1	8031	COSM6938295,	lung	carcinoma	p.L213Q	Substitution - Missense	1:156868568-156868568,	NEUTRAL	0.33887	28481359
NTRK1	8031	COSM6968432,	pancreas	carcinoma	p.A372T	Substitution - Missense	1:156873896-156873896,	NEUTRAL	0.30389	28481359
NTRK1	8031	COSM6982507,	breast	carcinoma	p.L244P	Substitution - Missense	1:156871636-156871636,	NEUTRAL	0.29696	28481359
NTRK1	8031	COSM48611,	lung	carcinoma	p.M375I	Substitution - Missense	1:156873907-156873907,	NEUTRAL	0.28638	18948947
NTRK1	8031	COSM6970405,	skin	malignant_melanoma	p.S204L	Substitution - Missense	1:156868541-156868541,	NEUTRAL	0.28562	28481359
NTRK1	8031	COSM6929811,	skin	malignant_melanoma	p.G169E	Substitution - Missense	1:156868181-156868181,	NEUTRAL	0.26502	28481359
NTRK1	8031	COSM6929811,	skin	malignant_melanoma	p.G169E	Substitution - Missense	1:156868181-156868181,	NEUTRAL	0.26502	28481359
NTRK1	8031	COSM5609662,	skin	malignant_melanoma	p.F124F	Substitution - coding silent	1:156866922-156866922,	NEUTRAL	0.26301	26343386
NTRK1	8031	COSM6942501,	oesophagus	carcinoma	p.P42S	Substitution - Missense	1:156861058-156861058,	NEUTRAL	0.2628	28481359
NTRK1	8031	COSM6971045,	lung	carcinoma	p.A377V	Substitution - Missense	1:156873912-156873912,	NEUTRAL	0.25716	28481359
NTRK1	8031	COSM6970100,	lung	carcinoma	p.A618S	Substitution - Missense	1:156879168-156879168,	NEUTRAL	0.24652	28481359
NTRK1	8031	COSM6946074,	large_intestine	carcinoma	p.F113L	Substitution - Missense	1:156864779-156864779,	NEUTRAL	0.23651	28481359
NTRK1	8031	COSM78208,	lung	carcinoma	p.R780G	Substitution - Missense	1:156881589-156881589,	NEUTRAL	0.23548	28481359
NTRK1	8031	COSM1217989,	large_intestine	carcinoma	p.R347C	Substitution - Missense	1:156873821-156873821,	NEUTRAL	0.23232	28481359
NTRK1	8031	COSM1217989,	soft_tissue	rhabdomyosarcoma	p.R347C	Substitution - Missense	1:156873821-156873821,	NEUTRAL	0.23232	28481359
NTRK1	8031	COSM6956018,	large_intestine	carcinoma	p.C191*	Substitution - Nonsense	1:156868248-156868248,	NEUTRAL	0.22993	28481359
NTRK1	8031	COSM6957211,	kidney	carcinoma	p.W12*	Substitution - Nonsense	1:156860969-156860969,	NEUTRAL	0.21588	28481359
NTRK1	8031	COSM6962909,	lung	carcinoma	p.R780L	Substitution - Missense	1:156881590-156881590,	NEUTRAL	0.2131	28481359
NTRK1	8031	COSM4808910,	large_intestine	carcinoma	p.P335L	Substitution - Missense	1:156873786-156873786,	NEUTRAL	0.20381	28481359
NTRK1	8031	COSM1651760,	lung	carcinoma	p.R780W	Substitution - Missense	1:156881589-156881589,	NEUTRAL	0.18316	28481359
NTRK1	8031	COSM6936636,	lung	carcinoma	p.T237M	Substitution - Missense	1:156868640-156868640,	NEUTRAL	0.18257	28481359
NTRK1	8031	COSM6936636,	prostate	carcinoma	p.T237M	Substitution - Missense	1:156868640-156868640,	NEUTRAL	0.18257	28481359
NTRK1	8031	COSM3376767,	large_intestine	carcinoma	p.R347H	Substitution - Missense	1:156873822-156873822,	NEUTRAL	0.16624	28481359
NTRK1	8031	COSM6973437,	prostate	carcinoma	p.L229P	Substitution - Missense	1:156868616-156868616,	NEUTRAL	0.16596	28481359
NTRK1	8031	COSM6908996,	endometrium	carcinoma	p.P397L	Substitution - Missense	1:156874395-156874395,	NEUTRAL	0.16132	28481359
NTRK1	8031	COSM6916498,	lung	carcinoma	p.S146*	Substitution - Nonsense	1:156868112-156868112,	NEUTRAL	0.15863	28481359
NTRK1	8031	COSM6916498,	lung	carcinoma	p.S146*	Substitution - Nonsense	1:156868112-156868112,	NEUTRAL	0.15863	28481359
NTRK1	8031	COSM6982540,	prostate	carcinoma	p.S204W	Substitution - Missense	1:156868541-156868541,	NEUTRAL	0.15517	28481359
NTRK1	8031	COSM48608,	large_intestine	carcinoma	p.R119H	Substitution - Missense	1:156864796-156864796,	NEUTRAL	0.15258	28481359
NTRK1	8031	COSM48608,	lung	carcinoma	p.R119H	Substitution - Missense	1:156864796-156864796,	NEUTRAL	0.15258	18948947
NTRK1	8031	COSM6924753,	breast	carcinoma	p.F395L	Substitution - Missense	1:156874390-156874390,	NEUTRAL	0.14597	28481359
NTRK1	8031	COSM6730801,	lung	carcinoma	p.R273L	Substitution - Missense	1:156871723-156871723,	NEUTRAL	0.14361	28481359
NTRK1	8031	COSM6960231,	large_intestine	carcinoma	p.L10F	Substitution - Missense	1:156860962-156860962,	NEUTRAL	0.14094	28481359
NTRK1	8031	COSM5128324,	lung	carcinoma	p.V341M	Substitution - Missense	1:156873803-156873803,	NEUTRAL	0.13445	28481359
NTRK1	8031	COSM5128324,	large_intestine	carcinoma	p.V341M	Substitution - Missense	1:156873803-156873803,	NEUTRAL	0.13445	28481359
NTRK1	8031	COSM5128324,	breast	carcinoma	p.V341M	Substitution - Missense	1:156873803-156873803,	NEUTRAL	0.13445	28481359
NTRK1	8031	COSM313392,	lung	carcinoma	p.L533L	Substitution - coding silent	1:156876177-156876177,	NEUTRAL	0.12174	22941188
NTRK1	8031	COSM20540,	stomach	carcinoma	p.H778H	Substitution - coding silent	1:156881585-156881585,	NEUTRAL	0.12068	Info_not_available
NTRK1	8031	COSM20540,	stomach	carcinoma	p.H778H	Substitution - coding silent	1:156881585-156881585,	NEUTRAL	0.12068	Info_not_available
NTRK1	8031	COSM6945468,	NS	malignant_melanoma	p.D270N	Substitution - Missense	1:156871713-156871713,	NEUTRAL	0.11985	28481359
NTRK1	8031	COSM6945468,	skin	carcinoma	p.D270N	Substitution - Missense	1:156871713-156871713,	NEUTRAL	0.11985	28481359
NTRK1	8031	COSM6945468,	large_intestine	carcinoma	p.D270N	Substitution - Missense	1:156871713-156871713,	NEUTRAL	0.11985	28481359
NTRK1	8031	COSM6939605,	large_intestine	carcinoma	p.P754T	Substitution - Missense	1:156881511-156881511,	NEUTRAL	0.11732	28481359
NTRK1	8031	COSM5609660,	skin	malignant_melanoma	p.G272G	Substitution - coding silent	1:156871721-156871721,	NEUTRAL	0.11343	26343386
NTRK1	8031	COSM313388,	lung	carcinoma	p.R342Q	Substitution - Missense	1:156873807-156873807,	NEUTRAL	0.1086	22941188
NTRK1	8031	COSM6978967,	lung	carcinoma	p.S326C	Substitution - Missense	1:156873758-156873758,	NEUTRAL	0.10556	28481359
NTRK1	8031	COSM6985058,	endometrium	carcinoma	p.S146L	Substitution - Missense	1:156868112-156868112,	NEUTRAL	0.10532	28481359
NTRK1	8031	COSM4990455,	skin	carcinoma	p.E83K	Substitution - Missense	1:156864388-156864388,	NEUTRAL	0.10441	25589618
NTRK1	8031	COSM6910426,	endometrium	carcinoma	p.R342W	Substitution - Missense	1:156873806-156873806,	NEUTRAL	0.09823	28481359
NTRK1	8031	COSM1259646,	kidney	carcinoma	p.V321M	Substitution - Missense	1:156873743-156873743,	NEUTRAL	0.09599	28481359
NTRK1	8031	COSM1259646,	penis	carcinoma	p.V321M	Substitution - Missense	1:156873743-156873743,	NEUTRAL	0.09599	28481359
NTRK1	8031	COSM6909457,	urinary_tract	carcinoma	p.A779G	Substitution - Missense	1:156881587-156881587,	NEUTRAL	0.08803	28481359
NTRK1	8031	COSM6926939,	lung	carcinoma	p.L471M	Substitution - Missense	1:156875576-156875576,	NEUTRAL	0.07793	28481359
NTRK1	8031	COSM1688778,	skin	malignant_melanoma	p.S320F	Substitution - Missense	1:156873741-156873741,	NEUTRAL	0.07337	28481359
NTRK1	8031	COSM6980440,	lung	carcinoma	p.S326T	Substitution - Missense	1:156873759-156873759,	NEUTRAL	0.06998	28481359
NTRK1	8031	COSM4990457,	skin	carcinoma	p.A225V	Substitution - Missense	1:156868604-156868604,	NEUTRAL	0.06132	25589618
NTRK1	8031	COSM3418158,	skin	malignant_melanoma	p.F105F	Substitution - coding silent	1:156864755-156864755,	NEUTRAL	0.05294	26343386
NTRK1	8031	COSM6940172,	lung	carcinoma	p.T292S	Substitution - Missense	1:156873656-156873656,	NEUTRAL	0.0438	28481359
NTRK1	8031	COSM1984626,	large_intestine	carcinoma	p.T434M	Substitution - Missense	1:156874955-156874955,	NEUTRAL	0.03613	28481359
NTRK1	8031	COSM48613,	lung	carcinoma	p.D776E	Substitution - Missense	1:156881579-156881579,	NEUTRAL	0.03561	18948947
NTRK1	8031	COSM5609658,	skin	malignant_melanoma	p.H178Y	Substitution - Missense	1:156868207-156868207,	NEUTRAL	0.03448	26343386
NTRK1	8031	COSM5609658,	NS	malignant_melanoma	p.H178Y	Substitution - Missense	1:156868207-156868207,	NEUTRAL	0.03448	28481359
NTRK1	8031	COSM6914523,	breast	carcinoma	p.E223K	Substitution - Missense	1:156868597-156868597,	NEUTRAL	0.0341	28481359
NTRK1	8031	COSM6935008,	large_intestine	carcinoma	p.R214Q	Substitution - Missense	1:156868571-156868571,	NEUTRAL	0.0313	28481359
NTRK1	8031	COSM3475493,	skin	carcinoma	p.F367F	Substitution - coding silent	1:156873883-156873883,	NEUTRAL	0.02347	25589618
NTRK1	8031	COSM6974839,	large_intestine	carcinoma	p.T414P	Substitution - Missense	1:156874615-156874615,	NEUTRAL	0.01	28481359
NTRK1	8031	COSM5020457,	soft_tissue	haemangioblastoma	p.?	Unknown	1:156879118-156879118,	Info_not_available	Info_not_available	25589003
NTRK1	8031	COSM5025384,	breast	carcinoma	p.I450I	Substitution - coding silent	1:156875004-156875004,	Info_not_available	0.65401	22722193
NTRK1	8031	COSM48887,	lung	carcinoma	p.Q80*	Substitution - Nonsense	1:156864379-156864379,	Info_not_available	0.62017	18948947
NTRK1	8031	COSM6987325,	breast, endometrium, kidney, large_intestine, lung, ovary, skin, soft_tissue	adnexal_tumour, carcinoma, leiomyosarcoma, malignant_melanoma	p.A225V, p.D596fs*62, p.E163Q, p.G643S, p.H151N, p.L512F, p.L585fs*6, p.L585fs*73, p.P309fs*10, p.P387L, p.P458_A463delPEDGLA, p.R654fs*13, p.R761Q, p.R88K, p.S320F	Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Substitution - Missense	1:156881533-156881533,	Info_not_available	0.60171, .63211, .66366, .679, .69825, .6983, Info_not_available	28481359
NTRK1	8031	COSM12886,	lung	carcinoma	p.L213L	Substitution - coding silent	1:156868569-156868569,	Info_not_available	0.5653	16140923