Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ABI2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical, physical association 12569093, 17101133, 27229929, 28514442, 7590236 0.52 BioGRID, IntAct, MINT ADAM15 pull down physical association 11741929 0.40 IntAct, MINT APP pull down association 11279131 0.35 IntAct, MINT BCL2L1 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 16631755 0.40 BioGRID, IntAct, MINT BRCA1 Affinity Capture-Western, Biochemical Activity, FRET, Reconstituted Complex, bimolecular fluorescence complementation physical, physical association 12024016, 17352427 0.37 BioGRID, IntAct, MINT CBL Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Far Western, Reconstituted Complex, experimental interaction detection phosphorylation reaction, physical 10829062, 11494134, 12475393, 14604282, 14725908, 15556646, 16955467, 19380743, 19823681, 20675402, 8626543, 9174058, 9195915 0.31 BioGRID, IntAct, MINT CDON Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical, physical association 19470755 0.52 BioGRID, IntAct, MINT CRK Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, nuclear magnetic resonance, peptide array, protein kinase assay, pull down association, phosphorylation reaction, physical, physical association 12097319, 12384576, 15696159, 17474147, 17515907, 18619508, 18835194, 19380743, 24412932, 8194526, 9747873 0.35, 0.44, 0.56 BioGRID, IntAct, MINT CRKL Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, protein kinase assay, pull down phosphorylation reaction, physical, physical association 14604282, 16443220, 16955467, 18835194, 19823681, 22286129, 24412932, 7926767, 8524328, 8978305, 9710592, 9820532 0.44, 0.67 BioGRID, IntAct, MINT CTNNB1 Affinity Capture-Western, anti bait coimmunoprecipitation, protein kinase assay phosphorylation reaction, physical, physical association 17318191, 23950177 0.54 BioGRID, IntAct, MINT EGFR PCA, Protein-peptide, Two-hybrid, protein array, ubiquitin reconstruction direct interaction, physical, physical association 16273093, 24658140, 25402006 0.59 BioGRID, IntAct, MINT EP300 imaging technique colocalization 16648821 0.27 IntAct, MINT ERBB2 Protein-peptide, protein array direct interaction, physical 16273093 0.44 BioGRID, IntAct, MINT ERBB3 Protein-peptide, protein array direct interaction, physical 16273093 0.44 BioGRID, IntAct, MINT ERBB4 Protein-peptide, protein array direct interaction, physical 16273093 0.44 BioGRID, IntAct, MINT HCK Affinity Capture-Western, pull down physical, physical association 10849448, 9407116 0.40 BioGRID, IntAct, MINT ITGB2 anti bait coimmunoprecipitation, pull down physical association 19234221 0.52 IntAct, MINT MAP4K1 peptide array, two hybrid physical association 17474147, 9346925 0.57 IntAct, MINT MAVS Affinity Capture-Western, Far Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, far western blotting physical, physical association 19914245 0.59 BioGRID, IntAct, MINT MED25 classical fluorescence spectroscopy direct interaction 19290556 0.44 IntAct, MINT MSH4 protein three hybrid physical association 16397227 0.37 IntAct, MINT MSH5 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, protein three hybrid, pull down, tandem affinity purification, two hybrid physical, physical association 16397227, 19442657, 22401567 0.82 BioGRID, IntAct, MINT MUC1 Affinity Capture-Western, Biochemical Activity, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, imaging technique, protein kinase assay, pull down colocalization, direct interaction, phosphorylation reaction, physical, physical association 16888623 0.66 BioGRID, IntAct, MINT PARK7 enzymatic study cleavage reaction 23831022 0.44 IntAct, MINT PRDX1 FRET, bimolecular fluorescence complementation physical, physical association 17352427 0.37 BioGRID, IntAct, MINT PRKCD anti bait coimmunoprecipitation physical association 16631755 0.40 IntAct, MINT PTBP3 anti bait coimmunoprecipitation association 22575643 0.35 IntAct, MINT PTPN1 phosphatase assay dephosphorylation reaction 16537444 0.44 IntAct, MINT RAD51 Affinity Capture-Western, Reconstituted Complex, pull down physical, physical association 10212258, 19427856, 21653319 0.40 BioGRID, IntAct, MINT RAPGEF1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, anti bait coimmunoprecipitation, peptide array, pull down physical, physical association 16443220, 17474147 0.66 BioGRID, IntAct, MINT SH3BP1 fluorescence technology physical association 17352427 0.40 IntAct, MINT SHB Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, pull down physical, physical association 17112510 0.52 BioGRID, IntAct, MINT SORBS3 anti tag coimmunoprecipitation, pull down direct interaction, physical association 16831423 0.40, 0.54 IntAct, MINT SPRR2A Reconstituted Complex, protein array direct interaction, physical 18155796 0.44 BioGRID, IntAct, MINT SRC Reconstituted Complex, anti bait coimmunoprecipitation, peptide array physical, physical association 11494128, 17318191, 17474147 0.59 BioGRID, IntAct, MINT TLN2 anti bait coimmunoprecipitation, pull down direct interaction, physical association 19234221 0.60 IntAct, MINT TOP1 anti bait coimmunoprecipitation, pull down direct interaction, physical association 15448168 0.60 IntAct, MINT TP73 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, pull down physical, physical association 10391250, 10391251, 11278685, 19442657, 25893286 0.40 BioGRID, IntAct, MINT VAV1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, pull down direct interaction, physical, physical association 11790798, 19234221 0.60 BioGRID, IntAct, MINT WASF1 Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, imaging technique, pull down colocalization, direct interaction, physical, physical association 10970852, 18559503 0.57 BioGRID, IntAct, MINT