Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ACTG1 pull down association 26966684 0.35 IntAct, MINT ACTN4 Two-hybrid physical 20936779 NA BioGRID ACTN4 two hybrid pooling approach physical association 20936779 0.37 IntAct AHSA1 Co-fractionation physical 26344197 NA BioGRID APEH Co-fractionation physical 22863883 NA BioGRID ARRB2 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 17620599 0.35 BioGRID, IntAct ATF3 Affinity Capture-Western, Reconstituted Complex physical 19647793 NA BioGRID ATG7 Co-fractionation physical 22863883 NA BioGRID ATP6V1C1 Co-fractionation physical 22863883 NA BioGRID BCL3 Affinity Capture-Western physical 16306601 NA BioGRID BPIFB3 Affinity Capture-MS, anti bait coimmunoprecipitation physical, physical association 17353931 0.40 BioGRID, IntAct BRCA1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 10792030 NA BioGRID CAND1 Co-fractionation physical 22863883 NA BioGRID CANX pull down association 26966684 0.35 IntAct, MINT CAPRIN1 pull down association 26966684 0.35 IntAct, MINT CASP3 Biochemical Activity physical 18723680 NA BioGRID CASP7 Biochemical Activity physical 18723680 NA BioGRID CCDC8 Affinity Capture-MS physical 24711643 NA BioGRID CDH1 Proximity Label-MS physical 25468996 NA BioGRID CHCHD3 pull down association 26966684 0.35 IntAct, MINT CIAPIN1 Co-fractionation physical 26344197 NA BioGRID CNOT7 anti bait coimmunoprecipitation, imaging technique colocalization, physical association 23386060 0.46 IntAct, MINT CREBBP Affinity Capture-Western, Biochemical Activity, Phenotypic Enhancement, Reconstituted Complex genetic, physical 15695802, 15894584, 16481475, 19915063, 25451029, 25733689, 8986769, 9037008 NA BioGRID CTNNBL1 Affinity Capture-MS physical 21385873 NA BioGRID CTTN Co-fractionation physical 22863883 NA BioGRID DCTN1 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct DDB1 Affinity Capture-Western, Two-hybrid, pull down, two hybrid physical, physical association 21988832 0.51 BioGRID, IntAct DDX58 anti bait coimmunoprecipitation physical association 24360797 0.40 IntAct DES pull down association 26966684 0.35 IntAct, MINT DNAJA3 anti bait coimmunoprecipitation physical association 21106534 0.40 IntAct DOCK4 Affinity Capture-MS physical 28514442 NA BioGRID DOT1L Affinity Capture-Western, Reconstituted Complex physical 22002246 NA BioGRID DTX3L Affinity Capture-Western physical 24886089, 26479788 NA BioGRID E2F1 Reconstituted Complex, display technology, tandem affinity purification physical, physical association 20195357 0.52 BioGRID, IntAct EBI-10096065 electrophoretic mobility supershift assay physical association 12788789 0.40 IntAct EBI-10096068 electrophoretic mobility supershift assay physical association 12788789 0.40 IntAct EBI-10096074 electrophoretic mobility supershift assay physical association 12788789 0.40 IntAct EBI-10097344 pull down physical association 19124747 0.40 IntAct EBI-10097347 pull down physical association 19124747 0.40 IntAct EBI-10178797 two hybrid array, two hybrid prey pooling approach, validated two hybrid physical association 25416956 0.56 IntAct EBI-9825772 electrophoretic mobility supershift assay association, physical association 8662591 0.50 IntAct, MINT EBI-9973887 electrophoretic mobility supershift assay physical association 19046253 0.40 IntAct EGFR Affinity Capture-Luminescence, Affinity Capture-MS, Affinity Capture-Western, PCA, Two-hybrid, anti tag coimmunoprecipitation, competition binding, electrophoretic mobility shift assay, luminescence based mammalian interactome mapping, ubiquitin reconstruction association, physical, physical association 10358079, 12070153, 15284024, 23956138, 24658140, 24797263, 25402006 0.71 BioGRID, IntAct, MINT EIF1AD Two-hybrid, two hybrid array, two hybrid pooling approach, two hybrid prey pooling approach, validated two hybrid physical, physical association 16189514, 25416956 0.67 BioGRID, IntAct EIF2AK2 Affinity Capture-Western, Reconstituted Complex physical 11278865, 9135145 NA BioGRID ELP2 Reconstituted Complex physical 10954736 NA BioGRID ENSG00000006210 chromatin immunoprecipitation assay association 25040843 0.35 IntAct ENSG00000049768 chromatin immunoprecipitation assay, enzyme linked immunosorbent assay association, physical association 19124747 0.50 IntAct ENSG00000099956 chromatin immunoprecipitation assay association 18267069 0.35 IntAct ENSG00000102524 chromatin immunoprecipitation assay association 23271704 0.35 IntAct ENSG00000125347 chromatin immunoprecipitation assay, electrophoretic mobility shift assay association, physical association 17525742, 19124747, 8810328 0.67 IntAct ENSG00000129521 chromatin immunoprecipitation assay association 19574556 0.35 IntAct ENSG00000137496 chromatin immunoprecipitation assay association 19046253 0.35 IntAct ENSG00000140279 chromatin immunoprecipitation assay association 21321110 0.35 IntAct ENSG00000145113 chromatin immunoprecipitation assay association 17525742 0.35 IntAct ENSG00000160182 chromatin immunoprecipitation assay association 25303530 0.35 IntAct ENSG00000171132 chromatin immunoprecipitation assay association 24825907 0.35 IntAct ENSG00000196208 chromatin immunoprecipitation assay association 25303530 0.35 IntAct ENSG00000255346 chromatin immunoprecipitation assay association 22348975 0.35 IntAct EP300 Affinity Capture-Western, Co-localization physical 10464260, 11134049, 11923478, 12403783, 15824515, 18566411, 19915063, 26479788, 26504087 NA BioGRID ERBB2 Co-localization, Protein-peptide, protein array, proximity ligation assay direct interaction, physical, physical association 16273093, 25241761 0.61 BioGRID, IntAct, MINT ERP44 pull down association 26966684 0.35 IntAct, MINT ESR1 anti tag coimmunoprecipitation association 25303530 0.35 IntAct ETFB pull down association 26966684 0.35 IntAct, MINT FANCC Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 10848598, 11520787, 14499622 NA BioGRID FANCE Affinity Capture-Western physical 26277624 NA BioGRID FARSB pull down association 26966684 0.35 IntAct, MINT FOS Co-localization, anti bait coimmunoprecipitation, proximity ligation assay physical, physical association 12788789, 25241761 0.59 BioGRID, IntAct FOXA3 Affinity Capture-MS, tandem affinity purification association, physical 25609649 0.35 BioGRID, IntAct, MINT G3BP1 Affinity Capture-MS physical 26777405 NA BioGRID GATA3 chromatin immunoprecipitation assay association 25303530 0.35 IntAct GFAP Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct GLO1 pull down association 26966684 0.35 IntAct, MINT GNB2 Affinity Capture-Western physical 23326349 NA BioGRID GSPT2 Co-fractionation physical 22863883 NA BioGRID GSTK1 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct GTF2I Reconstituted Complex physical 9584171 NA BioGRID HADH Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct HDAC1 Affinity Capture-Western physical 16481475 NA BioGRID HDAC3 Affinity Capture-Western physical 16481475 NA BioGRID HDAC4 Affinity Capture-Western physical 21571862 NA BioGRID HIRIP3 Co-fractionation physical 22863883 NA BioGRID HIST1H2BJ Affinity Capture-Western physical 26479788 NA BioGRID HIST2H3C Affinity Capture-Western physical 21689637 NA BioGRID HLA-B Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct HLA-DRB5 Affinity Capture-MS physical 26186194 NA BioGRID HSCB anti bait coimmunoprecipitation association 28380382 0.35 IntAct HSD17B4 pull down association 26966684 0.35 IntAct, MINT HSF1 Affinity Capture-Western physical 9880553 NA BioGRID HSP90AB1 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct HSP90B1 Affinity Capture-Western physical 18662321 NA BioGRID HSPA4L Co-fractionation physical 22863883 NA BioGRID HUWE1 Affinity Capture-MS physical 25147182 NA BioGRID IDE Co-fractionation physical 22863883 NA BioGRID IFNAR1 pull down association, physical association 9121453 0.50 IntAct, MINT IFNAR2 Reconstituted Complex, pull down association, physical, physical association 11301323, 9121453 0.50 BioGRID, IntAct, MINT IFNGR1 Affinity Capture-Western, Co-localization physical 10848598, 21689637 NA BioGRID IFNGR1 coimmunoprecipitation, competition binding, x-ray crystallography association 15780933, 8156998, 8662591 0.69 IntAct, MINT IGBP1 Affinity Capture-Western, Co-fractionation physical 19553685 NA BioGRID IL27RA Affinity Capture-Western, Reconstituted Complex physical 12734330 NA BioGRID IL2RB Reconstituted Complex physical 10602027 NA BioGRID IL6ST competition binding association 8662591 0.35 IntAct, MINT INA pull down association 26966684 0.35 IntAct, MINT IRAK1 Affinity Capture-Western physical 12856330 NA BioGRID IRF1 Affinity Capture-Western, Reconstituted Complex physical 10764778, 16512786 NA BioGRID IRF9 Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, cross-linking study association, physical 17923090, 24065129, 8943351 0.53 BioGRID, IntAct, MINT ISG15 Affinity Capture-MS physical 16009940 NA BioGRID ITGAV Affinity Capture-Western physical 23640055 NA BioGRID JAK1 Affinity Capture-Western physical 14978237, 15284024 NA BioGRID JAK2 Affinity Capture-Western, Co-localization, protein kinase assay phosphorylation reaction, physical 14978237, 15284024, 19834108, 20353823, 24255956 0.44 BioGRID, IntAct, MINT JMJD6 Co-fractionation physical 22863883 NA BioGRID JUN Affinity Capture-Western physical 10490649 NA BioGRID KARS Co-fractionation physical 22863883 NA BioGRID KDM3A anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down physical association 25535969 0.59 IntAct KIT Affinity Capture-Western, Biochemical Activity, Co-localization, Reconstituted Complex, proximity ligation assay physical, physical association 25241761, 9355737 0.40 BioGRID, IntAct KPNA1 Reconstituted Complex, pull down association, physical 10964507, 12048190, 26966684 0.35 BioGRID, IntAct, MINT KPNA6 pull down association 26966684 0.35 IntAct, MINT LDHB pull down association 26966684 0.35 IntAct, MINT LMO2 Two-hybrid, two hybrid pooling approach physical, physical association 16189514, 25416956 0.37 BioGRID, IntAct LZTR1 Two-hybrid physical 20211142 NA BioGRID MAVS Affinity Capture-MS, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical, physical association 21903422 0.58 BioGRID, IntAct MBD1 Affinity Capture-Western physical 19074829 NA BioGRID MCM5 Affinity Capture-Western, Reconstituted Complex physical 11248027, 9843502 NA BioGRID MLST8 Co-fractionation physical 19553685 NA BioGRID MT-ND4L two hybrid physical association 21988832 0.37 IntAct MTOR Affinity Capture-Western, Co-fractionation, Co-localization, proximity ligation assay physical, physical association 12807916, 19553685, 25241761 0.40 BioGRID, IntAct NAA10 Co-fractionation physical 22863883 NA BioGRID NAA15 Co-fractionation physical 22863883 NA BioGRID ND4L Two-hybrid physical 21988832 NA BioGRID NDUFS3 pull down association 26966684 0.35 IntAct, MINT NFKBIA Affinity Capture-Western physical 16481475 NA BioGRID NMD3 Co-fractionation physical 22939629 NA BioGRID NMI Reconstituted Complex, pull down physical, physical association 9989503 0.40 BioGRID, IntAct NOMO1 Two-hybrid, two hybrid physical, physical association 21988832 0.37 BioGRID, IntAct NOMO2 Two-hybrid physical 21988832 NA BioGRID NOMO3 two hybrid physical association 21988832 0.37 IntAct NR1H2 Affinity Capture-Western physical 27485016 NA BioGRID NR1H3 Affinity Capture-MS, Affinity Capture-Western physical 27485016 NA BioGRID NSF Co-fractionation physical 22939629 NA BioGRID NTRK1 Affinity Capture-MS physical 25921289 NA BioGRID OTUD4 Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical, physical association 25416956 0.56 BioGRID, IntAct PABPC3 pull down association 26966684 0.35 IntAct, MINT PAK2 Co-fractionation physical 26344197 NA BioGRID PARP9 Affinity Capture-Western physical 26479788 NA BioGRID PAWR Co-fractionation physical 22863883 NA BioGRID PDGFRA Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct PDGFRB proximity ligation assay physical association 23397142 0.40 IntAct PFKL pull down association 26966684 0.35 IntAct, MINT PGD pull down association 26966684 0.35 IntAct, MINT PHGDH Co-fractionation physical 22939629 NA BioGRID PIAS1 Affinity Capture-Western, Co-localization, Reconstituted Complex, Two-hybrid, proximity ligation assay physical, physical association 10805787, 11257227, 12171910, 17371985, 18566411, 25241761, 9724754 0.40 BioGRID, IntAct PIK3CA Biochemical Activity physical 11438544 NA BioGRID PLEC pull down association 26966684 0.35 IntAct, MINT PML Affinity Capture-Western physical 25733689, 25812002 NA BioGRID POR Two-hybrid physical 21988832 NA BioGRID POR two hybrid physical association 21988832 0.37 IntAct PPARA Affinity Capture-Western physical 26504087 NA BioGRID PPARD Affinity Capture-Western physical 26504087 NA BioGRID PPARG Affinity Capture-Western, Co-localization physical 26504087 NA BioGRID PRKCD Affinity Capture-Western, Biochemical Activity, Co-fractionation physical 11839738, 12807916, 12817007, 15322115, 19553685 NA BioGRID PRKCE Affinity Capture-Western physical 20353823 NA BioGRID PRMT1 Affinity Capture-Western, Biochemical Activity physical 11257227 NA BioGRID PRMT3 Biochemical Activity physical 11257227 NA BioGRID PSMC3 Affinity Capture-Western physical 19853614 NA BioGRID PTBP2 pull down association 26966684 0.35 IntAct, MINT PTK2 Affinity Capture-Western, Co-localization, Reconstituted Complex, proximity ligation assay physical, physical association 11278462, 20576130, 25241761 0.40 BioGRID, IntAct PTP4A3 anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct PTPA Affinity Capture-Western, Co-fractionation physical 19553685 NA BioGRID PTPN11 Two-hybrid physical 27229929 NA BioGRID PTPN2 Affinity Capture-Western physical 12171910, 19171783 NA BioGRID PYGL pull down association 26966684 0.35 IntAct, MINT RACK1 Affinity Capture-Western, Reconstituted Complex physical 11301323, 12960323 NA BioGRID RARA anti tag coimmunoprecipitation, chromatin immunoprecipitation assay, pull down association 25303530 0.53 IntAct RELA Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct RNF11 Affinity Capture-Western physical 19131965 NA BioGRID RPS6KB1 Co-fractionation physical 19553685 NA BioGRID RTF1 Co-fractionation physical 22863883 NA BioGRID RXRA Affinity Capture-Western, Two-hybrid, pull down, two hybrid physical, physical association 21988832 0.51 BioGRID, IntAct SARS Co-fractionation physical 22863883 NA BioGRID SHANK1 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct SHMT1 Co-fractionation physical 22863883 NA BioGRID SHMT2 Co-fractionation physical 22863883 NA BioGRID SMARCA2 Affinity Capture-Western physical 21079652 NA BioGRID SMARCA4 Affinity Capture-Western, Co-localization physical 16195385, 20353823, 21079652 NA BioGRID SMURF1 Affinity Capture-Western physical 22474288 NA BioGRID SNX1 Co-fractionation physical 22863883 NA BioGRID SNX2 Co-fractionation physical 22863883 NA BioGRID SNX6 Co-fractionation physical 22863883 NA BioGRID SPACA1 Affinity Capture-MS physical 26186194 NA BioGRID SPTAN1 Two-hybrid, pull down, two hybrid pooling approach association, physical, physical association 20936779, 26966684 0.55 BioGRID, IntAct, MINT SPTB Two-hybrid, two hybrid array, validated two hybrid physical, physical association 25814554 0.49 BioGRID, IntAct SPTBN1 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct SRC Affinity Capture-Western physical 10358079, 14978237, 9344858 NA BioGRID STAT1 Affinity Capture-Western, Co-crystal Structure, Co-purification, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, competition binding, cosedimentation in solution, cross-linking study, dynamic light scattering, molecular sieving, pull down, x-ray crystallography association, direct interaction, physical 15284440, 16007122, 18591661, 21914072, 8605877, 8621447, 9630226 0.62, 0.64, 0.65 BioGRID, IntAct, MINT STAT2 Affinity Capture-MS, Affinity Capture-Western, Co-localization, Co-purification, Reconstituted Complex, anti bait coimmunoprecipitation, coimmunoprecipitation, competition binding, cross-linking study, pull down association, physical, physical association 10446176, 10490982, 12048190, 15825084, 17923090, 24065129, 26966684, 28514442, 8605877, 8621447, 9724754 0.86 BioGRID, IntAct, MINT STAT3 Affinity Capture-MS, Affinity Capture-Western, Co-localization, Reconstituted Complex physical 11594781, 11722592, 12070153, 16007122, 25241761, 25609649, 28514442 NA BioGRID STAT3 competition binding, proximity ligation assay, pull down, tandem affinity purification association, physical association 25241761, 25609649, 26966684, 8662591 0.74 IntAct, MINT STAT4 Reconstituted Complex physical 21826217 NA BioGRID STAT5A Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct STK4 tandem affinity purification association 23386615 0.35 IntAct STMN1 pull down association 26966684 0.35 IntAct, MINT TBCA pull down association 26966684 0.35 IntAct, MINT TBCD Co-fractionation physical 22863883 NA BioGRID TES Affinity Capture-MS physical 28378594 NA BioGRID TEX264 Affinity Capture-MS physical 26186194 NA BioGRID TNFRSF1A Affinity Capture-Western physical 10848577 NA BioGRID TNK2 Affinity Capture-Western physical 28739485 NA BioGRID TRADD Affinity Capture-Western, Reconstituted Complex physical 10848577 NA BioGRID TRIM28 Affinity Capture-Western physical 18037959, 18381204 NA BioGRID TSNAX Co-fractionation physical 22863883 NA BioGRID TYK2 Biochemical Activity physical 12960323 NA BioGRID U2AF2 Affinity Capture-MS physical 26641092 NA BioGRID UBE2F anti bait coimmunoprecipitation physical association 17353931 0.40 IntAct UBE2I Biochemical Activity physical 14517261 NA BioGRID UBE2M pull down association 26966684 0.35 IntAct, MINT UCHL1 pull down association 26966684 0.35 IntAct, MINT UQCRC1 pull down association 26966684 0.35 IntAct, MINT USP13 Affinity Capture-Western physical 23940278 NA BioGRID USP2 Affinity Capture-Western physical 27434509 NA BioGRID VCP Affinity Capture-MS physical 23383273 NA BioGRID VDR Affinity Capture-Western, Reconstituted Complex physical 11909970 NA BioGRID VPS26A Co-fractionation physical 22863883 NA BioGRID VPS29 Co-fractionation physical 22863883 NA BioGRID XPO1 Affinity Capture-MS, Protein-peptide physical 22833565, 26673895 NA BioGRID YAP1 Co-fractionation physical 22863883 NA BioGRID