Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
INPP4A	6074	COSM6918725,	upper_aerodigestive_tract	carcinoma	p.K745T	Substitution - Missense	2:98565706-98565706,	PATHOGENIC	0.99783	28481359
INPP4A	6074	COSM6982634,	endometrium	carcinoma	p.K572N	Substitution - Missense	2:98555687-98555687,	PATHOGENIC	0.99707	28481359
INPP4A	6074	COSM6938455,	large_intestine	carcinoma	p.?	Unknown	2:98546696-98546696,	PATHOGENIC	0.99679	28481359
INPP4A	6074	COSM3963290,	lung	carcinoma	p.R376L	Substitution - Missense	2:98546658-98546658,	PATHOGENIC	0.99634	28481359
INPP4A	6074	COSM5059144,	large_intestine	carcinoma	p.A684T	Substitution - Missense	2:98564646-98564646,	PATHOGENIC	0.99623	28481359
INPP4A	6074	COSM5059144,	endometrium	carcinoma	p.A684T	Substitution - Missense	2:98564646-98564646,	PATHOGENIC	0.99623	28481359
INPP4A	6074	COSM6906894,	salivary_gland	carcinoma	p.W171*	Substitution - Nonsense	2:98537907-98537907,	PATHOGENIC	0.99612	28481359
INPP4A	6074	COSM6927094,	lung	carcinoma	p.?	Unknown	2:98537862-98537862,	PATHOGENIC	0.99612	28481359
INPP4A	6074	COSM6686023,	kidney	carcinoma	p.S223L	Substitution - Missense	2:98538979-98538979,	PATHOGENIC	0.99577	28481359
INPP4A	6074	COSM6929166,	large_intestine	carcinoid-endocrine_tumour	p.R376H	Substitution - Missense	2:98546658-98546658,	PATHOGENIC	0.99574	28481359
INPP4A	6074	COSM6983443,	large_intestine	carcinoma	p.A365T	Substitution - Missense	2:98546624-98546624,	PATHOGENIC	0.99574	28481359
INPP4A	6074	COSM6952115,	large_intestine	carcinoma	p.H149N	Substitution - Missense	2:98536186-98536186,	PATHOGENIC	0.99563	28481359
INPP4A	6074	COSM6962506,	urinary_tract	carcinoma	p.R848Q	Substitution - Missense	2:98572824-98572824,	PATHOGENIC	0.99547	28481359
INPP4A	6074	COSM6929728,	breast	carcinoma	p.D328H	Substitution - Missense	2:98546001-98546001,	PATHOGENIC	0.99509	28481359
INPP4A	6074	COSM6929728,	lung	carcinoma	p.D328H	Substitution - Missense	2:98546001-98546001,	PATHOGENIC	0.99509	28481359
INPP4A	6074	COSM1410202,	small_intestine	carcinoma	p.R231H	Substitution - Missense	2:98539549-98539549,	PATHOGENIC	0.9949	28481359
INPP4A	6074	COSM1410202,	lung	carcinoma	p.R231H	Substitution - Missense	2:98539549-98539549,	PATHOGENIC	0.9949	28481359
INPP4A	6074	COSM6982048,	lung	carcinoma	p.G134S	Substitution - Missense	2:98536141-98536141,	PATHOGENIC	0.99479	28481359
INPP4A	6074	COSM6977144,	urinary_tract	carcinoma	p.V770M	Substitution - Missense	2:98566042-98566042,	PATHOGENIC	0.9945	28481359
INPP4A	6074	COSM6942329,	lung	carcinoma	p.E730*	Substitution - Nonsense	2:98565660-98565660,	PATHOGENIC	0.99433	28481359
INPP4A	6074	COSM6933558,	breast	carcinoma	p.D146G	Substitution - Missense	2:98536178-98536178,	PATHOGENIC	0.99396	28481359
INPP4A	6074	COSM6967645,	skin	carcinoma	p.R342K	Substitution - Missense	2:98546044-98546044,	PATHOGENIC	0.99384	28481359
INPP4A	6074	COSM245035,	upper_aerodigestive_tract	carcinoma	p.A713S	Substitution - Missense	2:98564733-98564733,	PATHOGENIC	0.9938	25056374
INPP4A	6074	COSM6930741,	breast	carcinoma	p.D199N	Substitution - Missense	2:98538906-98538906,	PATHOGENIC	0.99366	28481359
INPP4A	6074	COSM6979395,	NS	carcinoma	p.D218N	Substitution - Missense	2:98538963-98538963,	PATHOGENIC	0.99366	28481359
INPP4A	6074	COSM6930168,	lung	carcinoma	p.K387R	Substitution - Missense	2:98546691-98546691,	PATHOGENIC	0.99337	28481359
INPP4A	6074	COSM6921572,	endometrium	carcinoma	p.I166T	Substitution - Missense	2:98537892-98537892,	PATHOGENIC	0.99333	28481359
INPP4A	6074	COSM4962736,	urinary_tract	carcinoma	p.A362V	Substitution - Missense	2:98546616-98546616,	PATHOGENIC	0.99328	28481359
INPP4A	6074	COSM6955467,	urinary_tract	carcinoma	p.?	Unknown	2:98545967-98545967,	PATHOGENIC	0.99311	28481359
INPP4A	6074	COSM6933440,	endometrium	carcinoma	p.R291Q	Substitution - Missense	2:98543930-98543930,	PATHOGENIC	0.99303	28481359
INPP4A	6074	COSM6976188,	lung	carcinoma	p.?	Unknown	2:98555809-98555809,	PATHOGENIC	0.99288	28481359
INPP4A	6074	COSM6952584,	lung	carcinoma	p.R829L	Substitution - Missense	2:98568621-98568621,	PATHOGENIC	0.99274	28481359
INPP4A	6074	COSM6962197,	oesophagus	carcinoma	p.F678V	Substitution - Missense	2:98563626-98563626,	PATHOGENIC	0.99264	28481359
INPP4A	6074	COSM4603978,	upper_aerodigestive_tract	carcinoma	p.P335A	Substitution - Missense	2:98546022-98546022,	PATHOGENIC	0.99205	25056374
INPP4A	6074	COSM4644474,	stomach	carcinoma	p.R244Q	Substitution - Missense	2:98539588-98539588,	PATHOGENIC	0.99158	28481359
INPP4A	6074	COSM6914898,	endometrium	carcinoma	p.A250T	Substitution - Missense	2:98539605-98539605,	PATHOGENIC	0.99158	28481359
INPP4A	6074	COSM6979917,	thyroid	carcinoma	p.?	Unknown	2:98559496-98559496,	PATHOGENIC	0.99133	28481359
INPP4A	6074	COSM6981677,	bone	osteosarcoma	p.E940Q	Substitution - Missense	2:98587492-98587492,	PATHOGENIC	0.99123	28481359
INPP4A	6074	COSM6918398,	skin	malignant_melanoma	p.E525K	Substitution - Missense	2:98554481-98554481,	PATHOGENIC	0.99075	28481359
INPP4A	6074	COSM6984327,	endometrium	carcinoma	p.R125I	Substitution - Missense	2:98535832-98535832,	PATHOGENIC	0.99061	28481359
INPP4A	6074	COSM6954931,	large_intestine	carcinoma	p.N873T	Substitution - Missense	2:98572899-98572899,	PATHOGENIC	0.99018	28481359
INPP4A	6074	COSM6929362,	NS	malignant_melanoma	p.S751F	Substitution - Missense	2:98565724-98565724,	PATHOGENIC	0.99011	28481359
INPP4A	6074	COSM6928323,	soft_tissue	other	p.P773S	Substitution - Missense	2:98566051-98566051,	PATHOGENIC	0.99005	28481359
INPP4A	6074	COSM6928323,	central_nervous_system	glioma	p.P773S	Substitution - Missense	2:98566051-98566051,	PATHOGENIC	0.99005	28481359
INPP4A	6074	COSM6972366,	small_intestine	carcinoma	p.P775L	Substitution - Missense	2:98566058-98566058,	PATHOGENIC	0.99005	28481359
INPP4A	6074	COSM6958756,	large_intestine	carcinoma	p.S645C	Substitution - Missense	2:98563527-98563527,	PATHOGENIC	0.98987	28481359
INPP4A	6074	COSM6950864,	lung	carcinoma	p.R515L	Substitution - Missense	2:98554452-98554452,	PATHOGENIC	0.98985	28481359
INPP4A	6074	COSM4853082,	oesophagus	carcinoma	p.R793Q	Substitution - Missense	2:98566112-98566112,	PATHOGENIC	0.98979	28481359
INPP4A	6074	COSM6929857,	lung	carcinoma	p.A436G	Substitution - Missense	2:98552914-98552914,	PATHOGENIC	0.98932	28481359
INPP4A	6074	COSM6923563,	soft_tissue	leiomyosarcoma	p.V119M	Substitution - Missense	2:98535813-98535813,	PATHOGENIC	0.98929	28481359
INPP4A	6074	COSM6946546,	lung	carcinoma	p.T683S	Substitution - Missense	2:98564643-98564643,	PATHOGENIC	0.98924	28481359
INPP4A	6074	COSM1024259,	endometrium	carcinoma	p.R938Q	Substitution - Missense	2:98587487-98587487,	PATHOGENIC	0.98906	28481359
INPP4A	6074	COSM199182,	breast	carcinoma	p.E969K	Substitution - Missense	2:98587579-98587579,	PATHOGENIC	0.98906	22722193
INPP4A	6074	COSM1024259,	endometrium	carcinoma	p.R938Q	Substitution - Missense	2:98587487-98587487,	PATHOGENIC	0.98906	28481359
INPP4A	6074	COSM6984323,	endometrium	carcinoma	p.R62Q	Substitution - Missense	2:98533410-98533410,	PATHOGENIC	0.98873	28481359
INPP4A	6074	COSM6929695,	skin	carcinoma	p.D561N	Substitution - Missense	2:98555652-98555652,	PATHOGENIC	0.98809	28481359
INPP4A	6074	COSM5901144,	NS	malignant_melanoma	p.P285S	Substitution - Missense	2:98543911-98543911,	PATHOGENIC	0.98784	28481359
INPP4A	6074	COSM6928142,	breast	carcinoma	p.Q787R	Substitution - Missense	2:98566094-98566094,	PATHOGENIC	0.98755	28481359
INPP4A	6074	COSM6914813,	small_intestine	carcinoma	p.E552G	Substitution - Missense	2:98555626-98555626,	PATHOGENIC	0.9874	28481359
INPP4A	6074	COSM6954456,	breast	carcinoma	p.Q353K	Substitution - Missense	2:98546588-98546588,	PATHOGENIC	0.98692	28481359
INPP4A	6074	COSM6968793,	breast	carcinoma	p.S100C	Substitution - Missense	2:98535756-98535756,	PATHOGENIC	0.98673	28481359
INPP4A	6074	COSM6980102,	lung	carcinoma	p.G207A	Substitution - Missense	2:98538931-98538931,	PATHOGENIC	0.98615	28481359
INPP4A	6074	COSM6927820,	lung	carcinoma	p.V195F	Substitution - Missense	2:98538894-98538894,	PATHOGENIC	0.98598	28481359
INPP4A	6074	COSM6914243,	skin	carcinoma	p.A661V	Substitution - Missense	2:98563576-98563576,	PATHOGENIC	0.98461	28481359
INPP4A	6074	COSM6912894,	skin	carcinoma	p.S255F	Substitution - Missense	2:98539621-98539621,	PATHOGENIC	0.98414	28481359
INPP4A	6074	COSM6954787,	large_intestine	carcinoma	p.?	Unknown	2:98568670-98568670,	PATHOGENIC	0.98393	28481359
INPP4A	6074	COSM6937617,	urinary_tract	carcinoma	p.P564T	Substitution - Missense	2:98555661-98555661,	PATHOGENIC	0.98232	28481359
INPP4A	6074	COSM6935686,	lung	carcinoma	p.V274A	Substitution - Missense	2:98543879-98543879,	PATHOGENIC	0.98157	28481359
INPP4A	6074	COSM4970415,	endometrium	carcinoma	p.A416T	Substitution - Missense	2:98552853-98552853,	PATHOGENIC	0.98151	28481359
INPP4A	6074	COSM6952451,	skin	malignant_melanoma	p.Q787*	Substitution - Nonsense	2:98566093-98566093,	PATHOGENIC	0.98125	28481359
INPP4A	6074	COSM6976755,	central_nervous_system	glioma	p.P783S	Substitution - Missense	2:98566081-98566081,	PATHOGENIC	0.98125	28481359
INPP4A	6074	COSM6967055,	prostate	carcinoma	p.T336K	Substitution - Missense	2:98546026-98546026,	PATHOGENIC	0.9811	28481359
INPP4A	6074	COSM6918443,	large_intestine	carcinoma	p.T86M	Substitution - Missense	2:98533482-98533482,	PATHOGENIC	0.97866	28481359
INPP4A	6074	COSM6918443,	urinary_tract	carcinoma	p.T86M	Substitution - Missense	2:98533482-98533482,	PATHOGENIC	0.97866	28481359
INPP4A	6074	COSM6973455,	upper_aerodigestive_tract	carcinoma	p.T81M	Substitution - Missense	2:98533467-98533467,	PATHOGENIC	0.97866	28481359
INPP4A	6074	COSM6970250,	lung	carcinoma	p.M232I	Substitution - Missense	2:98539553-98539553,	PATHOGENIC	0.97766	28481359
INPP4A	6074	COSM6956661,	large_intestine	carcinoma	p.G973R	Substitution - Missense	2:98587591-98587591,	PATHOGENIC	0.97506	28481359
INPP4A	6074	COSM6983674,	large_intestine	carcinoma	p.R949H	Substitution - Missense	2:98587520-98587520,	PATHOGENIC	0.97506	28481359
INPP4A	6074	COSM6956661,	large_intestine	carcinoma	p.G973R	Substitution - Missense	2:98587591-98587591,	PATHOGENIC	0.97506	28481359
INPP4A	6074	COSM6956661,	stomach	carcinoma	p.G973R	Substitution - Missense	2:98587591-98587591,	PATHOGENIC	0.97506	28481359
INPP4A	6074	COSM6982913,	skin	carcinoma	p.G136E	Substitution - Missense	2:98536148-98536148,	PATHOGENIC	0.97348	28481359
INPP4A	6074	COSM6960047,	large_intestine	carcinoma	p.R216Q	Substitution - Missense	2:98538958-98538958,	PATHOGENIC	0.97322	28481359
INPP4A	6074	COSM6913604,	central_nervous_system	glioma	p.P405S	Substitution - Missense	2:98552820-98552820,	PATHOGENIC	0.97146	28481359
INPP4A	6074	COSM6948700,	skin	malignant_melanoma	p.P564S	Substitution - Missense	2:98555661-98555661,	PATHOGENIC	0.96839	28481359
INPP4A	6074	COSM6949479,	large_intestine	carcinoma	p.C614Y	Substitution - Missense	2:98559466-98559466,	PATHOGENIC	0.96779	28481359
INPP4A	6074	COSM6973413,	skin	malignant_melanoma	p.S395L	Substitution - Missense	2:98552791-98552791,	PATHOGENIC	0.96758	28481359
INPP4A	6074	COSM6974602,	lung	carcinoma	p.C931F	Substitution - Missense	2:98577134-98577134,	PATHOGENIC	0.96643	28481359
INPP4A	6074	COSM6980224,	large_intestine	carcinoma	p.R180W	Substitution - Missense	2:98537933-98537933,	PATHOGENIC	0.96572	28481359
INPP4A	6074	COSM4604888,	upper_aerodigestive_tract	carcinoma	p.R850H	Substitution - Missense	2:98572830-98572830,	PATHOGENIC	0.96328	25056374
INPP4A	6074	COSM6962749,	central_nervous_system	glioma	p.E930K	Substitution - Missense	2:98577130-98577130,	PATHOGENIC	0.96326	28481359
INPP4A	6074	COSM3660029,	lung	carcinoma	p.S894I	Substitution - Missense	2:98577023-98577023,	PATHOGENIC	0.96096	28481359
INPP4A	6074	COSM6934658,	breast	carcinoma	p.L739F	Substitution - Missense	2:98565689-98565689,	PATHOGENIC	0.95872	28481359
INPP4A	6074	COSM6921116,	large_intestine	carcinoma	p.R515*	Substitution - Nonsense	2:98554451-98554451,	PATHOGENIC	0.95793	28481359
INPP4A	6074	COSM1210696,	thyroid	carcinoma	p.R901H	Substitution - Missense	2:98577044-98577044,	PATHOGENIC	0.95756	28481359
INPP4A	6074	COSM6916517,	breast	carcinoma	p.R885H	Substitution - Missense	2:98576996-98576996,	PATHOGENIC	0.95556	28481359
INPP4A	6074	COSM6963442,	skin	carcinoma	p.D311N	Substitution - Missense	2:98543989-98543989,	PATHOGENIC	0.95547	28481359
INPP4A	6074	COSM6960851,	lung	carcinoma	p.Q172H	Substitution - Missense	2:98537911-98537911,	PATHOGENIC	0.94971	28481359
INPP4A	6074	COSM6946443,	large_intestine	carcinoma	p.V520M	Substitution - Missense	2:98554466-98554466,	PATHOGENIC	0.94863	28481359
INPP4A	6074	COSM6972362,	small_intestine	carcinoma	p.T460M	Substitution - Missense	2:98554287-98554287,	PATHOGENIC	0.94853	28481359
INPP4A	6074	COSM6973083,	central_nervous_system	glioma	p.T129I	Substitution - Missense	2:98535844-98535844,	PATHOGENIC	0.94813	28481359
INPP4A	6074	COSM2914177,	oesophagus	carcinoma	p.R544H	Substitution - Missense	2:98555602-98555602,	PATHOGENIC	0.94775	28481359
INPP4A	6074	COSM6956934,	skin	carcinoma	p.S754F	Substitution - Missense	2:98565733-98565733,	PATHOGENIC	0.94094	28481359
INPP4A	6074	COSM6986222,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.I541L	Substitution - Missense	2:98555592-98555592,	PATHOGENIC	0.94046	28481359
INPP4A	6074	COSM3840352,	prostate	carcinoma	p.A476T	Substitution - Missense	2:98554334-98554334,	PATHOGENIC	0.9395	28481359
INPP4A	6074	COSM6981102,	lung	carcinoma	p.Q806H	Substitution - Missense	2:98566152-98566152,	PATHOGENIC	0.93813	28481359
INPP4A	6074	COSM6910751,	central_nervous_system	glioma	p.P576S	Substitution - Missense	2:98555697-98555697,	PATHOGENIC	0.93659	28481359
INPP4A	6074	COSM2914123,	upper_aerodigestive_tract	carcinoma	p.V190I	Substitution - Missense	2:98537963-98537963,	PATHOGENIC	0.93593	25056374
INPP4A	6074	COSM6963386,	large_intestine	carcinoma	p.D766N	Substitution - Missense	2:98566030-98566030,	PATHOGENIC	0.93465	28481359
INPP4A	6074	COSM6968820,	lung	carcinoma	p.L266V	Substitution - Missense	2:98539653-98539653,	PATHOGENIC	0.93392	28481359
INPP4A	6074	COSM6966102,	skin	malignant_melanoma	p.R15L	Substitution - Missense	2:98520092-98520092,	PATHOGENIC	0.92412	28481359
INPP4A	6074	COSM6950274,	breast	carcinoma	p.L303V	Substitution - Missense	2:98543965-98543965,	PATHOGENIC	0.92387	28481359
INPP4A	6074	COSM6954928,	large_intestine	carcinoma	p.S594F	Substitution - Missense	2:98555752-98555752,	PATHOGENIC	0.92057	28481359
INPP4A	6074	COSM3910834,	lung	carcinoma	p.S490L	Substitution - Missense	2:98554377-98554377,	PATHOGENIC	0.91661	28481359
INPP4A	6074	COSM6981044,	NS	carcinoma	p.S578R	Substitution - Missense	2:98555705-98555705,	PATHOGENIC	0.91466	28481359
INPP4A	6074	COSM6982630,	endometrium	carcinoma	p.R9H	Substitution - Missense	2:98520074-98520074,	PATHOGENIC	0.91444	28481359
INPP4A	6074	COSM6960442,	skin	malignant_melanoma	p.G31S	Substitution - Missense	2:98520139-98520139,	PATHOGENIC	0.91444	28481359
INPP4A	6074	COSM6909464,	urinary_tract	carcinoma	p.S578T	Substitution - Missense	2:98555704-98555704,	PATHOGENIC	0.91265	28481359
INPP4A	6074	COSM6940290,	urinary_tract	carcinoma	p.R860W	Substitution - Missense	2:98572859-98572859,	PATHOGENIC	0.9118	28481359
INPP4A	6074	COSM1024246,	endometrium	carcinoma	p.R793*	Substitution - Nonsense	2:98566111-98566111,	PATHOGENIC	0.89281	28481359
INPP4A	6074	COSM6962679,	lung	carcinoma	p.D587G	Substitution - Missense	2:98555731-98555731,	PATHOGENIC	0.89004	28481359
INPP4A	6074	COSM6970876,	lung	carcinoma	p.S33C	Substitution - Missense	2:98520146-98520146,	PATHOGENIC	0.87661	28481359
INPP4A	6074	COSM6979399,	NS	carcinoma	p.R376C	Substitution - Missense	2:98546657-98546657,	PATHOGENIC	0.84747	28481359
INPP4A	6074	COSM6943965,	breast	carcinoma	p.R544C	Substitution - Missense	2:98555601-98555601,	PATHOGENIC	0.84567	28481359
INPP4A	6074	COSM6966082,	skin	malignant_melanoma	p.L830V	Substitution - Missense	2:98568623-98568623,	PATHOGENIC	0.83943	28481359
INPP4A	6074	COSM6938341,	lung	carcinoma	p.R15S	Substitution - Missense	2:98520091-98520091,	PATHOGENIC	0.83824	28481359
INPP4A	6074	COSM1024256,	endometrium	carcinoma	p.R933C	Substitution - Missense	2:98577139-98577139,	PATHOGENIC	0.83448	28481359
INPP4A	6074	COSM2914226,	endometrium	carcinoma	p.A753T	Substitution - Missense	2:98565729-98565729,	NEUTRAL	0.2706	28481359
INPP4A	6074	COSM2914226,	endometrium	carcinoma	p.A753T	Substitution - Missense	2:98565729-98565729,	NEUTRAL	0.2706	28481359
INPP4A	6074	COSM6926215,	skin	carcinoma	p.P777S	Substitution - Missense	2:98566063-98566063,	NEUTRAL	0.21061	28481359
INPP4A	6074	COSM6937621,	urinary_tract	carcinoma	p.A781T	Substitution - Missense	2:98566075-98566075,	NEUTRAL	0.20886	28481359
INPP4A	6074	COSM6941876,	large_intestine	carcinoma	p.T611A	Substitution - Missense	2:98555802-98555802,	NEUTRAL	0.14817	28481359
INPP4A	6074	COSM6932362,	central_nervous_system, large_intestine, lung, ovary, stomach, vulva	carcinoma, glioma	p.?, p.C590fs*21, p.E917fs*27, p.L108fs*13, p.P588S, p.Q550_L554delQKERL	Deletion - Frameshift, Deletion - In frame, Substitution - Missense, Unknown	2:98577091-98577091,	Info_not_available	0.64504, Info_not_available	28481359