Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases AMPH Affinity Capture-Western physical 12558988 NA BioGRID ANGPTL4 anti bait coimmunoprecipitation association 21397862 0.35 IntAct APC Co-localization physical 25241761 NA BioGRID APC proximity ligation assay physical association 25241761 0.40 IntAct APP Reconstituted Complex physical 21832049 NA BioGRID ARHGAP26 Reconstituted Complex physical 8649427 NA BioGRID ASAP1 Affinity Capture-Western physical 17893324 NA BioGRID ATG12 Two-hybrid physical 16189514 NA BioGRID BBS10 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT BCAR1 Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, filter binding physical, physical association 10753828, 11577104, 11839772, 12135674, 12615911, 15673687, 21034468, 21855630, 8649427, 8810278, 9285683 0.59 BioGRID, IntAct, MINT BIN1 Affinity Capture-Western physical 12558988 NA BioGRID BMX Affinity Capture-Western, Reconstituted Complex physical 11331870 NA BioGRID CBL Affinity Capture-Western, Co-localization physical 12771190, 17675501, 22203672 NA BioGRID CCNA1 Co-localization, anti bait coimmunoprecipitation, proximity ligation assay physical, physical association 17353931, 25241761 0.59 BioGRID, IntAct CCR5 Affinity Capture-Western physical 10384144 NA BioGRID CD36 pull down association 20037584 0.35 IntAct CDH5 Affinity Capture-Western physical 22720799 NA BioGRID CIB1 Affinity Capture-Western physical 12881299 NA BioGRID CRK Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, two hybrid array, validated two hybrid physical, physical association 10085298, 12615911, 25814554, 7561682 0.63 BioGRID, IntAct CRKL proximity ligation assay physical association 23397142 0.40 IntAct CSK Affinity Capture-Western physical 7529872 NA BioGRID CTTN Affinity Capture-Western physical 17893324 NA BioGRID CXCR4 Affinity Capture-Western physical 11668182 NA BioGRID DAG1 Affinity Capture-Western physical 18341635 NA BioGRID DCC Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation association, physical 15494733, 20434207 0.35 BioGRID, IntAct DDX39A Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT DEF6 Two-hybrid physical 25416956 NA BioGRID DOCK1 Affinity Capture-Western physical 12615911 NA BioGRID DOK4 Two-hybrid, two hybrid array, validated two hybrid physical, physical association 25814554 0.49 BioGRID, IntAct DVL1 anti bait coimmunoprecipitation association 20224554 0.35 IntAct, MINT DVL1P1 anti bait coimmunoprecipitation association 20224554 0.35 IntAct, MINT EEF1G Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT EGFR Affinity Capture-Western, PCA, Two-hybrid, anti bait coimmunoprecipitation, ubiquitin reconstruction association, physical, physical association 10806474, 15657067, 24658140, 25402006 0.55 BioGRID, IntAct ELAVL1 Affinity Capture-RNA physical 19322201 NA BioGRID EPHA2 Affinity Capture-Western, anti bait coimmunoprecipitation, fluorescence microscopy physical, physical association 10655584 0.49 BioGRID, IntAct EPS8L2 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT ERBB2 Affinity Capture-Western, Co-localization, coimmunoprecipitation, proximity ligation assay physical, physical association 12600989, 21034468, 25241761 0.59 BioGRID, IntAct EZR Reconstituted Complex physical 11468295 NA BioGRID F13A1 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT FBP1 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT FGR Affinity Capture-Western physical 12387730 NA BioGRID FLT1 proximity ligation assay physical association 23397142 0.40 IntAct FYN Affinity Capture-Western, Co-crystal Structure physical 11278857, 12558988 NA BioGRID GAPDH Co-fractionation physical 18206965 NA BioGRID GIT1 Affinity Capture-Western, Reconstituted Complex physical 10938112, 12473661, 12629171 NA BioGRID GNB1 Affinity Capture-Western physical 19917775 NA BioGRID GNG2 Affinity Capture-Western physical 19917775 NA BioGRID GRB2 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, pull down, two hybrid association, physical, physical association 10085298, 10806474, 12005431, 12558988, 21900206, 7597091, 8649427 0.55 BioGRID, IntAct, MINT GRB7 Affinity Capture-Luminescence, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, luminescence based mammalian interactome mapping, two hybrid array, validated two hybrid physical, physical association 10446223, 11119718, 25814554 0.57 BioGRID, IntAct GSK3B Affinity Capture-Western physical 11809746 NA BioGRID GSN Affinity Capture-Western physical 11577104 NA BioGRID HCK Affinity Capture-Luminescence, Two-hybrid, luminescence based mammalian interactome mapping, two hybrid array physical, physical association 25814554 0.51 BioGRID, IntAct HES1 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT HNRNPL Affinity Capture-RNA physical 28611215 NA BioGRID HSP90AA1 Affinity Capture-Luminescence physical 22939624 NA BioGRID HSP90AB1 luminescence based mammalian interactome mapping physical association 22939624 0.40 IntAct IGF1R Affinity Capture-Western physical 10082579 NA BioGRID IQGAP1 Affinity Capture-Western physical 24639526 NA BioGRID IRS1 Affinity Capture-Western, Two-hybrid physical 9822703 NA BioGRID ITGA4 Affinity Capture-Western physical 11919182 NA BioGRID ITGAV Affinity Capture-Western physical 12844492, 19889638 NA BioGRID ITGAV proximity ligation assay physical association 23397142 0.40 IntAct ITGB1 Affinity Capture-Western, Co-localization physical 19889638, 25792870, 26992741 NA BioGRID ITGB3 Affinity Capture-Western, Reconstituted Complex physical 11927607, 19889638, 9169439 NA BioGRID ITGB4 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical association 27178753 0.52 IntAct, MINT ITGB5 Affinity Capture-Western, Reconstituted Complex physical 11927607, 15673687 NA BioGRID JAK2 Affinity Capture-Western physical 10925297, 9553131 NA BioGRID LPXN Affinity Capture-MS, Two-hybrid, two hybrid physical, physical association 21900206, 28514442 0.37 BioGRID, IntAct, MINT LYN Affinity Capture-Western, Two-hybrid, coimmunoprecipitation, two hybrid array physical, physical association 11389892, 25814554, 9169439 0.57 BioGRID, IntAct, MINT MAL anti bait coimmunoprecipitation association 22366891 0.35 IntAct MAPK8IP3 Affinity Capture-Western physical 12226752 NA BioGRID MDM2 Reconstituted Complex physical 18206965 NA BioGRID NACAD Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT NASP Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT NCK1 Affinity Capture-Western, Reconstituted Complex physical 11950595, 8879209 NA BioGRID NCK2 Affinity Capture-Western, Reconstituted Complex physical 11950595 NA BioGRID NEDD9 Affinity Capture-Western, Two-hybrid physical 8668148 NA BioGRID NEO1 Affinity Capture-Western, Two-hybrid physical 15494733 NA BioGRID NTRK1 Affinity Capture-MS physical 25921289 NA BioGRID OTUD6B Co-fractionation physical 26344197 NA BioGRID PARP1 Co-fractionation physical 18206965 NA BioGRID PDCD6IP Affinity Capture-Western physical 12771190 NA BioGRID PIAS1 Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct PIK3CA anti bait coimmunoprecipitation association 22402981 0.35 IntAct PIK3R1 Affinity Capture-Western, Far Western physical 10973983, 11119718, 19889638, 7537275 NA BioGRID PIK3R2 anti bait coimmunoprecipitation association 22402981 0.35 IntAct PIK3R3 Affinity Capture-Luminescence, Two-hybrid, anti bait coimmunoprecipitation, luminescence based mammalian interactome mapping, two hybrid array association, physical, physical association 22402981, 25814554 0.63 BioGRID, IntAct PKD1 Affinity Capture-Western physical 11113628 NA BioGRID PKM protein kinase assay phosphorylation reaction 24606918 0.44 IntAct PLCG1 Affinity Capture-Western, proximity ligation assay physical, physical association 10430888, 23397142 0.40 BioGRID, IntAct PPP1CA Affinity Capture-Western physical 17274640 NA BioGRID PPP1CB Affinity Capture-Western physical 11513739, 17274640 NA BioGRID PRKG1 Affinity Capture-MS physical 28514442 NA BioGRID PTAFR Affinity Capture-Western physical 20576130 NA BioGRID PTEN Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, proximity ligation assay physical, physical association 10400703, 11857088, 15717329, 23397142, 9927060 0.40 BioGRID, IntAct PTK2 Co-crystal Structure, x-ray crystallography direct interaction, physical 12005431, 24480479 0.44 BioGRID, IntAct, MINT PTPN11 Affinity Capture-Western physical 10082579, 21726809 NA BioGRID PTPN23 anti bait coimmunoprecipitation, fluorescence technology, protein kinase assay, pull down colocalization, direct interaction, phosphorylation reaction, physical association 18835089 0.64 IntAct, MINT PTPN6 Affinity Capture-Luminescence, Two-hybrid, luminescence based mammalian interactome mapping, two hybrid array, validated two hybrid physical, physical association 25814554 0.57 BioGRID, IntAct PTRH2 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 21383007 0.40 BioGRID, IntAct PXN Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, confocal microscopy, far western blotting, fluorescence microscopy, pull down colocalization, physical, physical association 10330411, 10455189, 10753828, 10980697, 11514617, 11919182, 21034468, 21741599, 22270917, 7561682, 8922390, 9054445, 9422762, 9442086, 9756887 0.88 BioGRID, IntAct RAC1 Two-hybrid, two hybrid pooling approach physical, physical association 20936779 0.37 BioGRID, IntAct RB1CC1 Affinity Capture-Western, Reconstituted Complex physical 10769033 NA BioGRID RBSN Affinity Capture-Western physical 19931244 NA BioGRID RET Co-localization, proximity ligation assay physical, physical association 25241761 0.40 BioGRID, IntAct RHOU anti tag coimmunoprecipitation physical association 18086875 0.40 IntAct SAE1 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct SELE Reconstituted Complex physical 8609175 NA BioGRID SERPINB2 Affinity Capture-MS physical 28514442 NA BioGRID SH2D1A Two-hybrid, two hybrid array, validated two hybrid physical, physical association 25814554 0.49 BioGRID, IntAct SH2D1B Two-hybrid, two hybrid array physical, physical association 25814554 0.37 BioGRID, IntAct SH2D2A Affinity Capture-Luminescence, Two-hybrid, luminescence based mammalian interactome mapping, two hybrid array, validated two hybrid physical, physical association 25814554 0.57 BioGRID, IntAct SH3KBP1 Affinity Capture-Western physical 12771190 NA BioGRID SHC1 Affinity Capture-Western physical 11980671 NA BioGRID SOCS2 Two-hybrid physical 16189514 NA BioGRID SOCS3 Affinity Capture-Western, Two-hybrid physical 16007195, 18031698, 25416956 NA BioGRID SRC Affinity Capture-Western, Co-localization, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, proximity ligation assay, two hybrid array association, physical, physical association 10085298, 11119718, 11980671, 12387730, 12558988, 12615911, 16291744, 16966330, 17525734, 21034468, 21855630, 22402981, 23065768, 23242524, 25241761, 25814554, 9822703 0.92 BioGRID, IntAct, MINT SRPK1 Biochemical Activity physical 23602568 NA BioGRID SRPK1 protein kinase assay phosphorylation reaction 23602568 0.44 IntAct STAP2 Affinity Capture-Western physical 17675501 NA BioGRID STAT1 Affinity Capture-Western, Co-localization, Reconstituted Complex, proximity ligation assay physical, physical association 11278462, 20576130, 25241761 0.40 BioGRID, IntAct STAT3 Affinity Capture-Western, Co-localization physical 10925297, 25241761 NA BioGRID STAT3 proximity ligation assay physical association 25241761 0.40 IntAct STUB1 Affinity Capture-Western physical 22734001 NA BioGRID SYK Affinity Capture-Western physical 9169439, 9342235 NA BioGRID TEK Co-localization physical 25792870 NA BioGRID TGFB1I1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, two hybrid physical, physical association 11463817, 21900206, 9422762, 9756887, 9858471 0.57 BioGRID, IntAct, MINT TLN1 Affinity Capture-Western, Reconstituted Complex physical 7622520, 9442086 NA BioGRID TNS3 far western blotting, fluorescence microscopy, pull down colocalization, physical association 19732724 0.56 IntAct TP53 Affinity Capture-Western, Co-localization, Reconstituted Complex, anti bait coimmunoprecipitation, confocal microscopy, proximity ligation assay, pull down colocalization, direct interaction, physical, physical association 15855171, 18206965, 19857493, 25241761 0.76 BioGRID, IntAct, MINT TRIM15 PCA physical 25450970 NA BioGRID TRIM25 Affinity Capture-RNA physical 29117863 NA BioGRID TRIM72 Affinity Capture-Western physical 24344130 NA BioGRID TRIP6 Affinity Capture-Western physical 14688263 NA BioGRID TRMT6 Co-fractionation physical 26344197 NA BioGRID TSC1 Affinity Capture-Western physical 17043358 NA BioGRID TSC2 Affinity Capture-Western, Reconstituted Complex physical 17043358 NA BioGRID UBE2H Affinity Capture-Western physical 24344130 NA BioGRID VPS16 Affinity Capture-MS, anti tag coimmunoprecipitation association, physical 26496610 0.35 BioGRID, IntAct YES1 Affinity Capture-Western, Two-hybrid, proximity ligation assay physical, physical association 12558988, 23397142, 25416956 0.40 BioGRID, IntAct ZNF331 Two-hybrid, two hybrid physical, physical association 21900206 0.37 BioGRID, IntAct, MINT