Gene Name | HGNC ID | COSMIC_MutID | Primary site | Primary histology | AA-Mutation | Mutation Type | Genomic Position | FATHMM prediction | FATHMM score | Literature evidence |
PTPN14 | 9647 | COSM5025510, | breast | carcinoma | p.S158F | Substitution - Missense | 1:214411721-214411721, | PATHOGENIC | 0.98905 | 22722193 |
PTPN14 | 9647 | COSM314579, | lung | carcinoma | p.A763V | Substitution - Missense | 1:214383567-214383567, | PATHOGENIC | 0.98769 | 22941188 |
PTPN14 | 9647 | COSM32483, | breast | carcinoma | p.Q159E | Substitution - Missense | 1:214411719-214411719, | PATHOGENIC | 0.98472 | 16959974 |
PTPN14 | 9647 | COSM1581553, | haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm | p.P1115L | Substitution - Missense | 1:214364603-214364603, | PATHOGENIC | 0.98025 | 23292937 |
PTPN14 | 9647 | COSM1581553, | haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm | p.P1115L | Substitution - Missense | 1:214364603-214364603, | PATHOGENIC | 0.98025 | 23292937 |
PTPN14 | 9647 | COSM1581553, | haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm | p.P1115L | Substitution - Missense | 1:214364603-214364603, | PATHOGENIC | 0.98025 | 23292937 |
PTPN14 | 9647 | COSM32454, | breast | carcinoma | p.H360P | Substitution - Missense | 1:214384776-214384776, | PATHOGENIC | 0.89548 | 16959974 |
PTPN14 | 9647 | COSM1581554, | haematopoietic_and_lymphoid_tissue | lymphoid_neoplasm | p.V759M | Substitution - Missense | 1:214383580-214383580, | NEUTRAL | 0.26631 | 23292937 |
PTPN14 | 9647 | COSM1658952, | salivary_gland | carcinoma | p.P797L | Substitution - Missense | 1:214383465-214383465, | NEUTRAL | 0.19556 | 23778141 |