Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
BMPR1A	1076	COSM6930447,	lung	carcinoma	p.A379P	Substitution - Missense	10:86919438-86919438,	PATHOGENIC	0.99879	28481359
BMPR1A	1076	COSM5049681,	oesophagus	carcinoma	p.?	Unknown	10:86919470-86919470,	PATHOGENIC	0.99836	24686850
BMPR1A	1076	COSM20560,	stomach	carcinoma	p.R486Q	Substitution - Missense	10:86923490-86923490,	PATHOGENIC	0.99594	Info_not_available
BMPR1A	1076	COSM20479,	large_intestine	carcinoma	p.W487*	Substitution - Nonsense	10:86923493-86923493,	PATHOGENIC	0.99594	Info_not_available
BMPR1A	1076	COSM20479,	large_intestine	carcinoma	p.W487*	Substitution - Nonsense	10:86923493-86923493,	PATHOGENIC	0.99594	Info_not_available
BMPR1A	1076	COSM20560,	stomach	carcinoma	p.R486Q	Substitution - Missense	10:86923490-86923490,	PATHOGENIC	0.99594	Info_not_available
BMPR1A	1076	COSM1580604,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q304K	Substitution - Missense	10:86919213-86919213,	PATHOGENIC	0.99545	23292937
BMPR1A	1076	COSM1603818,	liver	carcinoma	p.Y453F	Substitution - Missense	10:86923391-86923391,	PATHOGENIC	0.99486	Info_not_available
BMPR1A	1076	COSM6929844,	prostate	carcinoma	p.E468K	Substitution - Missense	10:86923435-86923435,	PATHOGENIC	0.9946	28481359
BMPR1A	1076	COSM4382532,	large_intestine	carcinoma	p.R480Q	Substitution - Missense	10:86923472-86923472,	PATHOGENIC	0.9946	28481359
BMPR1A	1076	COSM6984497,	endometrium	carcinoma	p.P397A	Substitution - Missense	10:86921542-86921542,	PATHOGENIC	0.99423	28481359
BMPR1A	1076	COSM921000,	large_intestine	carcinoma	p.D208Y	Substitution - Missense	10:86912331-86912331,	PATHOGENIC	0.99306	28481359
BMPR1A	1076	COSM6960636,	upper_aerodigestive_tract	carcinoma	p.I288V	Substitution - Missense	10:86917320-86917320,	PATHOGENIC	0.99253	28481359
BMPR1A	1076	COSM6960636,	upper_aerodigestive_tract	carcinoma	p.I288V	Substitution - Missense	10:86917320-86917320,	PATHOGENIC	0.99253	28481359
BMPR1A	1076	COSM93968,	breast	carcinoma	p.A357T	Substitution - Missense	10:86919372-86919372,	PATHOGENIC	0.9923	20668451
BMPR1A	1076	COSM93968,	central_nervous_system	glioma	p.A357T	Substitution - Missense	10:86919372-86919372,	PATHOGENIC	0.9923	26487540
BMPR1A	1076	COSM48256,	lung	carcinoma	p.T520M	Substitution - Missense	10:86923679-86923679,	PATHOGENIC	0.99205	18948947
BMPR1A	1076	COSM6931869,	central_nervous_system	glioma	p.S510F	Substitution - Missense	10:86923649-86923649,	PATHOGENIC	0.99204	28481359
BMPR1A	1076	COSM6960097,	lung	carcinoma	p.G217D	Substitution - Missense	10:86912359-86912359,	PATHOGENIC	0.99193	28481359
BMPR1A	1076	COSM6930332,	urinary_tract	carcinoma	p.E313*	Substitution - Nonsense	10:86919240-86919240,	PATHOGENIC	0.99193	28481359
BMPR1A	1076	COSM6975998,	endometrium	carcinoma	p.A505T	Substitution - Missense	10:86923633-86923633,	PATHOGENIC	0.99096	28481359
BMPR1A	1076	COSM95696,	lung	carcinoma	p.?	Unknown	10:86890225-86890225,	PATHOGENIC	0.99044	20668451
BMPR1A	1076	COSM6914793,	prostate	carcinoma	p.E439G	Substitution - Missense	10:86921669-86921669,	PATHOGENIC	0.99005	28481359
BMPR1A	1076	COSM6915375,	upper_aerodigestive_tract	carcinoma	p.A294P	Substitution - Missense	10:86919183-86919183,	PATHOGENIC	0.9897	28481359
BMPR1A	1076	COSM6924662,	breast	carcinoma	p.D90N	Substitution - Missense	10:86892164-86892164,	PATHOGENIC	0.98769	28481359
BMPR1A	1076	COSM6936508,	lung	carcinoma	p.L225W	Substitution - Missense	10:86912383-86912383,	PATHOGENIC	0.98744	28481359
BMPR1A	1076	COSM6914095,	oesophagus	carcinoma	p.N73D	Substitution - Missense	10:86890211-86890211,	PATHOGENIC	0.98714	28481359
BMPR1A	1076	COSM6925888,	large_intestine	carcinoma	p.V402L	Substitution - Missense	10:86921557-86921557,	PATHOGENIC	0.98667	28481359
BMPR1A	1076	COSM197910,	large_intestine	carcinoma	p.R494*	Substitution - Nonsense	10:86923600-86923600,	PATHOGENIC	0.98459	23700467
BMPR1A	1076	COSM6945916,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	10:86890226-86890226,	PATHOGENIC	0.9814	28481359
BMPR1A	1076	COSM6911291,	upper_aerodigestive_tract	carcinoma	p.?	Unknown	10:86899793-86899793,	PATHOGENIC	0.97857	28481359
BMPR1A	1076	COSM6939370,	lung	carcinoma	p.?	Unknown	10:86899793-86899793,	PATHOGENIC	0.9762	28481359
BMPR1A	1076	COSM6978232,	endometrium	carcinoma	p.L59*	Substitution - Nonsense	10:86890170-86890170,	PATHOGENIC	0.97567	28481359
BMPR1A	1076	COSM6971971,	small_intestine	carcinoma	p.R120P	Substitution - Missense	10:86899819-86899819,	PATHOGENIC	0.97419	28481359
BMPR1A	1076	COSM6969890,	lung	carcinoma	p.E123Q	Substitution - Missense	10:86899827-86899827,	PATHOGENIC	0.9741	28481359
BMPR1A	1076	COSM6954486,	large_intestine	carcinoma	p.R244*	Substitution - Nonsense	10:86917188-86917188,	PATHOGENIC	0.97191	28481359
BMPR1A	1076	COSM20748,	kidney	carcinoma	p.F58Y	Substitution - Missense	10:86890167-86890167,	PATHOGENIC	0.97017	20054297
BMPR1A	1076	COSM20748,	kidney	carcinoma	p.F58Y	Substitution - Missense	10:86890167-86890167,	PATHOGENIC	0.97017	20054297
BMPR1A	1076	COSM5019036,	soft_tissue	haemangioblastoma	p.D380D	Substitution - coding silent	10:86919443-86919443,	PATHOGENIC	0.97015	25589003
BMPR1A	1076	COSM5019036,	soft_tissue	haemangioblastoma	p.D380D	Substitution - coding silent	10:86919443-86919443,	PATHOGENIC	0.97015	25589003
BMPR1A	1076	COSM3441228,	large_intestine	carcinoma	p.R191C	Substitution - Missense	10:86912280-86912280,	PATHOGENIC	0.96616	28481359
BMPR1A	1076	COSM6959326,	large_intestine	carcinoma	p.T33I	Substitution - Missense	10:86890092-86890092,	PATHOGENIC	0.96505	28481359
BMPR1A	1076	COSM5977661,	central_nervous_system	glioma	p.P140T	Substitution - Missense	10:86899878-86899878,	PATHOGENIC	0.96449	26487540
BMPR1A	1076	COSM5977661,	central_nervous_system	glioma	p.P140T	Substitution - Missense	10:86899878-86899878,	PATHOGENIC	0.96449	26487540
BMPR1A	1076	COSM6939124,	lung	carcinoma	p.D148N	Substitution - Missense	10:86900038-86900038,	PATHOGENIC	0.96184	28481359
BMPR1A	1076	COSM6971642,	lung	carcinoma	p.H31Y	Substitution - Missense	10:86890085-86890085,	PATHOGENIC	0.95932	28481359
BMPR1A	1076	COSM6967018,	large_intestine	carcinoma	p.?	Unknown	10:86919171-86919171,	PATHOGENIC	0.9592	28481359
BMPR1A	1076	COSM6915133,	lung	carcinoma	p.M1I	Substitution - Missense	10:86876021-86876021,	PATHOGENIC	0.95355	28481359
BMPR1A	1076	COSM6971581,	breast	carcinoma	p.L26V	Substitution - Missense	10:86890070-86890070,	PATHOGENIC	0.95017	28481359
BMPR1A	1076	COSM4990006,	skin	carcinoma	p.S416S	Substitution - coding silent	10:86921601-86921601,	PATHOGENIC	0.94544	25589618
BMPR1A	1076	COSM6960063,	large_intestine	carcinoma	p.C61*	Substitution - Nonsense	10:86890177-86890177,	PATHOGENIC	0.94475	28481359
BMPR1A	1076	COSM6937830,	urinary_tract	carcinoma	p.R442C	Substitution - Missense	10:86921677-86921677,	PATHOGENIC	0.94447	28481359
BMPR1A	1076	COSM4889316,	lung	carcinoma	p.M35I	Substitution - Missense	10:86890099-86890099,	PATHOGENIC	0.94136	28481359
BMPR1A	1076	COSM1349417,	endometrium	carcinoma	p.R486W	Substitution - Missense	10:86923489-86923489,	PATHOGENIC	0.92484	28481359
BMPR1A	1076	COSM1349417,	large_intestine	carcinoma	p.R486W	Substitution - Missense	10:86923489-86923489,	PATHOGENIC	0.92484	28481359
BMPR1A	1076	COSM1349417,	large_intestine	carcinoma	p.R486W	Substitution - Missense	10:86923489-86923489,	PATHOGENIC	0.92484	28481359
BMPR1A	1076	COSM6450475,	NS	carcinoma	p.R471C	Substitution - Missense	10:86923444-86923444,	PATHOGENIC	0.92387	28481359
BMPR1A	1076	COSM6928533,	breast	carcinoma	p.I436F	Substitution - Missense	10:86921659-86921659,	PATHOGENIC	0.92345	28481359
BMPR1A	1076	COSM6968424,	kidney	carcinoma	p.Q212H	Substitution - Missense	10:86912345-86912345,	PATHOGENIC	0.91985	28481359
BMPR1A	1076	COSM6916680,	lung	carcinoma	p.L369F	Substitution - Missense	10:86919408-86919408,	PATHOGENIC	0.9089	28481359
BMPR1A	1076	COSM1645447,	large_intestine	carcinoma	p.R273*	Substitution - Nonsense	10:86917275-86917275,	PATHOGENIC	0.89667	23700467
BMPR1A	1076	COSM1645447,	stomach	carcinoma	p.R273*	Substitution - Nonsense	10:86917275-86917275,	PATHOGENIC	0.89667	28481359
BMPR1A	1076	COSM93967,	lung	carcinoma	p.M167I	Substitution - Missense	10:86900097-86900097,	PATHOGENIC	0.89627	20668451
BMPR1A	1076	COSM6975391,	large_intestine	carcinoma	p.L59I	Substitution - Missense	10:86890169-86890169,	PATHOGENIC	0.86604	28481359
BMPR1A	1076	COSM6945648,	urinary_tract	carcinoma	p.S19C	Substitution - Missense	10:86876074-86876074,	PATHOGENIC	0.71309	28481359
BMPR1A	1076	COSM6983738,	pancreas	carcinoid-endocrine_tumour	p.F147L	Substitution - Missense	10:86900037-86900037,	NEUTRAL	0.44841	28481359
BMPR1A	1076	COSM6974388,	skin	carcinoma	p.R20H	Substitution - Missense	10:86876077-86876077,	NEUTRAL	0.01607	28481359
BMPR1A	1076	COSM6986485,	large_intestine, lung, pancreas, prostate, skin, urinary_tract	carcinoma, malignant_melanoma	p.C124fs*8, p.C125delC, p.F147fs*18, p.L307_I308ins*, p.L50fs*18, p.L59fs*1, p.M470fs*3, p.N367fs*32, p.P201L, p.P2S, p.V141fs*8, p.Y103fs*1	Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Insertion - In frame, Substitution - Missense	10:86923439-86923440,	Info_not_available	0.68307, Info_not_available	28481359