Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
TRAF2	12032	COSM6984084,	large_intestine	carcinoma	p.V288I	Substitution - Missense	9:136920417-136920417,	PATHOGENIC	0.99809	28481359
TRAF2	12032	COSM6956468,	skin	malignant_melanoma	p.Q311*	Substitution - Nonsense	9:136920486-136920486,	PATHOGENIC	0.99511	28481359
TRAF2	12032	COSM3216712,	endometrium	carcinoma	p.A302V	Substitution - Missense	9:136920460-136920460,	PATHOGENIC	0.9943	28481359
TRAF2	12032	COSM6986772,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.H51R	Substitution - Missense	9:136898892-136898892,	PATHOGENIC	0.98769	28481359
TRAF2	12032	COSM6983558,	liver	carcinoma	p.L396Q	Substitution - Missense	9:136923900-136923900,	PATHOGENIC	0.98684	28481359
TRAF2	12032	COSM3216692,	lung	carcinoma	p.E236K	Substitution - Missense	9:136920261-136920261,	PATHOGENIC	0.98683	28481359
TRAF2	12032	COSM6961736,	stomach	carcinoma	p.C192Y	Substitution - Missense	9:136909966-136909966,	PATHOGENIC	0.98558	28481359
TRAF2	12032	COSM6949068,	kidney	carcinoma	p.?	Unknown	9:136916616-136916616,	PATHOGENIC	0.98515	28481359
TRAF2	12032	COSM6973703,	large_intestine	carcinoma	p.R97H	Substitution - Missense	9:136900444-136900444,	PATHOGENIC	0.98378	28481359
TRAF2	12032	COSM6930006,	kidney	carcinoma	p.H307L	Substitution - Missense	9:136920475-136920475,	PATHOGENIC	0.98349	28481359
TRAF2	12032	COSM6973476,	upper_aerodigestive_tract	carcinoma	p.A2T	Substitution - Missense	9:136898744-136898744,	PATHOGENIC	0.98242	28481359
TRAF2	12032	COSM6955726,	pancreas	carcinoma	p.E292D	Substitution - Missense	9:136920431-136920431,	PATHOGENIC	0.9809	28481359
TRAF2	12032	COSM6953514,	skin	carcinoma	p.P44L	Substitution - Missense	9:136898871-136898871,	PATHOGENIC	0.98086	28481359
TRAF2	12032	COSM6983222,	endometrium	carcinoma	p.R440Q	Substitution - Missense	9:136925714-136925714,	PATHOGENIC	0.97826	28481359
TRAF2	12032	COSM6975364,	breast	carcinoma	p.E242Q	Substitution - Missense	9:136920279-136920279,	PATHOGENIC	0.96317	28481359
TRAF2	12032	COSM6940970,	urinary_tract	carcinoma	p.D462N	Substitution - Missense	9:136925779-136925779,	PATHOGENIC	0.95479	28481359
TRAF2	12032	COSM6939354,	skin	malignant_melanoma	p.R308Q	Substitution - Missense	9:136920478-136920478,	PATHOGENIC	0.95291	28481359
TRAF2	12032	COSM4993292,	skin	carcinoma	p.S476F	Substitution - Missense	9:136925822-136925822,	PATHOGENIC	0.95229	25589618
TRAF2	12032	COSM6977339,	endometrium	carcinoma	p.P449S	Substitution - Missense	9:136925740-136925740,	PATHOGENIC	0.95177	28481359
TRAF2	12032	COSM6928980,	central_nervous_system	glioma	p.P449L	Substitution - Missense	9:136925741-136925741,	PATHOGENIC	0.94776	28481359
TRAF2	12032	COSM6807199,	upper_aerodigestive_tract	carcinoma	p.R393C	Substitution - Missense	9:136923890-136923890,	PATHOGENIC	0.92576	28481359
TRAF2	12032	COSM6964181,	skin	malignant_melanoma	p.M345I	Substitution - Missense	9:136921112-136921112,	PATHOGENIC	0.92356	28481359
TRAF2	12032	COSM6941160,	NS	carcinoma	p.S483F	Substitution - Missense	9:136925843-136925843,	PATHOGENIC	0.92247	28481359
TRAF2	12032	COSM6941160,	NS	carcinoma	p.S483F	Substitution - Missense	9:136925843-136925843,	PATHOGENIC	0.92247	28481359
TRAF2	12032	COSM6931860,	central_nervous_system	glioma	p.G10D	Substitution - Missense	9:136898769-136898769,	PATHOGENIC	0.91346	28481359
TRAF2	12032	COSM6961921,	pancreas	carcinoid-endocrine_tumour	p.G193D	Substitution - Missense	9:136909969-136909969,	PATHOGENIC	0.91077	28481359
TRAF2	12032	COSM3655875,	central_nervous_system	glioma	p.P130S	Substitution - Missense	9:136908091-136908091,	PATHOGENIC	0.8999	28481359
TRAF2	12032	COSM6950075,	large_intestine	carcinoma	p.R486W	Substitution - Missense	9:136925851-136925851,	PATHOGENIC	0.8883	28481359
TRAF2	12032	COSM6964183,	skin	malignant_melanoma	p.A347T	Substitution - Missense	9:136921116-136921116,	PATHOGENIC	0.88195	28481359
TRAF2	12032	COSM6960190,	skin	malignant_melanoma	p.A36S	Substitution - Missense	9:136898846-136898846,	PATHOGENIC	0.87919	28481359
TRAF2	12032	COSM6938198,	breast	carcinoma	p.S64C	Substitution - Missense	9:136899596-136899596,	PATHOGENIC	0.8496	28481359
TRAF2	12032	COSM6987401,	breast	carcinoma	p.L15V	Substitution - Missense	9:136898783-136898783,	PATHOGENIC	0.83308	28481359
TRAF2	12032	COSM6964727,	lung	carcinoma	p.M345L	Substitution - Missense	9:136921110-136921110,	PATHOGENIC	0.78854	28481359
TRAF2	12032	COSM6980162,	breast	carcinoma	p.I394M	Substitution - Missense	9:136923895-136923895,	NEUTRAL	0.3753	28481359
TRAF2	12032	COSM6965961,	skin	malignant_melanoma	p.A280T	Substitution - Missense	9:136920393-136920393,	NEUTRAL	0.30569	28481359
TRAF2	12032	COSM6971278,	prostate	carcinoma	p.E135K	Substitution - Missense	9:136908106-136908106,	NEUTRAL	0.29619	28481359
TRAF2	12032	COSM6967350,	skin	malignant_melanoma	p.R144C	Substitution - Missense	9:136908133-136908133,	NEUTRAL	0.25618	28481359
TRAF2	12032	COSM3216702,	endometrium	carcinoma	p.E273K	Substitution - Missense	9:136920372-136920372,	NEUTRAL	0.23935	28481359
TRAF2	12032	COSM5979821,	urinary_tract	carcinoma	p.V106I	Substitution - Missense	9:136900470-136900470,	NEUTRAL	0.10215	28481359
TRAF2	12032	COSM4993290,	skin	carcinoma	p.V214V	Substitution - coding silent	9:136916579-136916579,	NEUTRAL	0.09715	25589618
TRAF2	12032	COSM6963497,	skin	carcinoma	p.A173T	Substitution - Missense	9:136908220-136908220,	NEUTRAL	0.07883	28481359
TRAF2	12032	COSM6974386,	skin	carcinoma	p.S266P	Substitution - Missense	9:136920351-136920351,	NEUTRAL	0.02521	28481359
TRAF2	12032	COSM96249,	lung	carcinoma	p.P417P	Substitution - coding silent	9:136923964-136923964,	Info_not_available	0.6151	20668451
TRAF2	12032	COSM6959835,	biliary_tract, breast, central_nervous_system, large_intestine, lung, skin	carcinoma, glioma, malignant_melanoma	p.G10fs*70, p.K196delK, p.L317fs*1, p.P9fs*77, p.S348fs*71, p.S408_V412>IR, p.S5N	Complex - deletion inframe, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Substitution - Missense	9:136923934-136923948,	Info_not_available	0.57397, Info_not_available	28481359