Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
EPHA4	3388	COSM32815,	large_intestine	carcinoma	p.Q948*	Substitution - Nonsense	2:221426468-221426468,	PATHOGENIC	0.99802	16959974
EPHA4	3388	COSM4991699,	skin	carcinoma	p.G705V	Substitution - Missense	2:221437083-221437083,	PATHOGENIC	0.99195	25589618
EPHA4	3388	COSM3782129,	oesophagus	carcinoma	p.R357L	Substitution - Missense	2:221482600-221482600,	PATHOGENIC	0.99154	24686850
EPHA4	3388	COSM94197,	lung	carcinoma	p.A748S	Substitution - Missense	2:221436503-221436503,	PATHOGENIC	0.98728	20668451
EPHA4	3388	COSM3045954,	oesophagus	carcinoma	p.A291D	Substitution - Missense	2:221501124-221501124,	PATHOGENIC	0.98683	24686850
EPHA4	3388	COSM94198,	lung	carcinoma	p.N82I	Substitution - Missense	2:221564309-221564309,	PATHOGENIC	0.98514	20668451
EPHA4	3388	COSM4991701,	skin	carcinoma	p.E647K	Substitution - Missense	2:221442964-221442964,	PATHOGENIC	0.98337	25589618
EPHA4	3388	COSM4991703,	skin	carcinoma	p.R198C	Substitution - Missense	2:221563962-221563962,	PATHOGENIC	0.97509	25589618
EPHA4	3388	COSM4991705,	skin	carcinoma	p.I89I	Substitution - coding silent	2:221564287-221564287,	PATHOGENIC	0.92854	25589618
EPHA4	3388	COSM48332,	lung	carcinoma	p.E670D	Substitution - Missense	2:221442893-221442893,	PATHOGENIC	0.91917	18948947
EPHA4	3388	COSM5048809,	oesophagus	carcinoma	p.L335F	Substitution - Missense	2:221482665-221482665,	PATHOGENIC	0.8681	24686850
EPHA4	3388	COSM3045978,	skin	carcinoma	p.V197V	Substitution - coding silent	2:221563963-221563963,	PATHOGENIC	0.76953	25589618
EPHA4	3388	COSM95850,	lung	carcinoma	p.P824P	Substitution - coding silent	2:221434166-221434166,	NEUTRAL	0.41635	20668451
EPHA4	3388	COSM1129305,	soft_tissue	haemangioblastoma	p.T960T	Substitution - coding silent	2:221426109-221426109,	NEUTRAL	0.05341	25589003
EPHA4	3388	COSM1129305,	soft_tissue	haemangioblastoma	p.T960T	Substitution - coding silent	2:221426109-221426109,	NEUTRAL	0.05341	25589003
EPHA4	3388	COSM1129305,	soft_tissue	haemangioblastoma	p.T960T	Substitution - coding silent	2:221426109-221426109,	NEUTRAL	0.05341	25589003
EPHA4	3388	COSM1129305,	soft_tissue	haemangioblastoma	p.T960T	Substitution - coding silent	2:221426109-221426109,	NEUTRAL	0.05341	25589003
EPHA4	3388	COSM20493,	large_intestine	carcinoma	p.T893T	Substitution - coding silent	2:221429969-221429969,	NEUTRAL	0.03737	Info_not_available
EPHA4	3388	COSM20493,	large_intestine	carcinoma	p.T893T	Substitution - coding silent	2:221429969-221429969,	NEUTRAL	0.03737	Info_not_available
EPHA4	3388	COSM5977592,	central_nervous_system	glioma	p.N606fs*22	Deletion - Frameshift	2:221443566-221443566,	Info_not_available	Info_not_available	26487540