Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
JAK1	6190	COSM6962484,	prostate	carcinoma	p.?	Unknown	1:64867209-64867209,	PATHOGENIC	0.99814	28481359
JAK1	6190	COSM6962484,	prostate	carcinoma	p.?	Unknown	1:64867209-64867209,	PATHOGENIC	0.99814	28481359
JAK1	6190	COSM6957256,	penis	carcinoma	p.A1049V	Substitution - Missense	1:64836210-64836210,	PATHOGENIC	0.99796	28481359
JAK1	6190	COSM6946071,	large_intestine	carcinoma	p.?	Unknown	1:64869310-64869310,	PATHOGENIC	0.99771	28481359
JAK1	6190	COSM4771395,	breast	carcinoma	p.S295*	Substitution - Nonsense	1:64866972-64866972,	PATHOGENIC	0.99767	24185512
JAK1	6190	COSM5415929,	endometrium	carcinoma	p.E284*	Substitution - Nonsense	1:64867006-64867006,	PATHOGENIC	0.99767	25233892
JAK1	6190	COSM6127283,	cervix	carcinoma	p.E284K	Substitution - Missense	1:64867006-64867006,	PATHOGENIC	0.99748	28481359
JAK1	6190	COSM6959386,	central_nervous_system	glioma	p.?	Unknown	1:64835507-64835507,	PATHOGENIC	0.99698	28481359
JAK1	6190	COSM6975753,	skin	carcinoma	p.E210K	Substitution - Missense	1:64869330-64869330,	PATHOGENIC	0.99679	28481359
JAK1	6190	COSM6920852,	breast	carcinoma	p.W1047*	Substitution - Nonsense	1:64836215-64836215,	PATHOGENIC	0.99659	28481359
JAK1	6190	COSM6974034,	biliary_tract	carcinoma	p.E883*	Substitution - Nonsense	1:64841247-64841247,	PATHOGENIC	0.99578	28481359
JAK1	6190	COSM4943283,	breast	carcinoma	p.S154*	Substitution - Nonsense	1:64873392-64873392,	PATHOGENIC	0.99578	24185512
JAK1	6190	COSM5609179,	skin	malignant_melanoma	p.P148T	Substitution - Missense	1:64873411-64873411,	PATHOGENIC	0.99561	26343386
JAK1	6190	COSM5448879,	large_intestine	carcinoma	p.P148H	Substitution - Missense	1:64873410-64873410,	PATHOGENIC	0.99561	28481359
JAK1	6190	COSM41774,	prostate	carcinoma	p.T593M	Substitution - Missense	1:64847653-64847653,	PATHOGENIC	0.99555	28481359
JAK1	6190	COSM41774,	large_intestine	carcinoma	p.T593M	Substitution - Missense	1:64847653-64847653,	PATHOGENIC	0.99555	19900094
JAK1	6190	COSM5609184,	skin	malignant_melanoma	p.P222S	Substitution - Missense	1:64867192-64867192,	PATHOGENIC	0.99536	26343386
JAK1	6190	COSM5609184,	NS	malignant_melanoma	p.P222S	Substitution - Missense	1:64867192-64867192,	PATHOGENIC	0.99536	28481359
JAK1	6190	COSM5566982,	thyroid	carcinoma	p.R873H	Substitution - Missense	1:64841276-64841276,	PATHOGENIC	0.99522	28481359
JAK1	6190	COSM6933817,	lung	carcinoma	p.C1131F	Substitution - Missense	1:64834635-64834635,	PATHOGENIC	0.9948	28481359
JAK1	6190	COSM6974527,	testis	germ_cell_tumour	p.G600E	Substitution - Missense	1:64847632-64847632,	PATHOGENIC	0.99474	28481359
JAK1	6190	COSM6948081,	prostate	carcinoma	p.D121N	Substitution - Missense	1:64873492-64873492,	PATHOGENIC	0.99473	28481359
JAK1	6190	COSM6948081,	large_intestine	carcinoma	p.D121N	Substitution - Missense	1:64873492-64873492,	PATHOGENIC	0.99473	28481359
JAK1	6190	COSM6948081,	prostate	carcinoma	p.D121N	Substitution - Missense	1:64873492-64873492,	PATHOGENIC	0.99473	28481359
JAK1	6190	COSM6906682,	stomach	carcinoma	p.H117R	Substitution - Missense	1:64873503-64873503,	PATHOGENIC	0.99457	29420467
JAK1	6190	COSM6920851,	breast	carcinoma	p.S1066C	Substitution - Missense	1:64836159-64836159,	PATHOGENIC	0.99455	28481359
JAK1	6190	COSM6909689,	breast	carcinoma	p.S1062C	Substitution - Missense	1:64836171-64836171,	PATHOGENIC	0.99455	28481359
JAK1	6190	COSM4818990,	endometrium	carcinoma	p.E314K	Substitution - Missense	1:64866916-64866916,	PATHOGENIC	0.99446	27159395
JAK1	6190	COSM6937580,	urinary_tract	carcinoma	p.T1070N	Substitution - Missense	1:64836147-64836147,	PATHOGENIC	0.9941	28481359
JAK1	6190	COSM4606336,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T901R	Substitution - Missense	1:64839743-64839743,	PATHOGENIC	0.99403	22237106
JAK1	6190	COSM6941322,	breast	carcinoma	p.H628P	Substitution - Missense	1:64847548-64847548,	PATHOGENIC	0.99398	28481359
JAK1	6190	COSM6921484,	lung	carcinoma	p.V194F	Substitution - Missense	1:64869378-64869378,	PATHOGENIC	0.99373	28481359
JAK1	6190	COSM6916975,	breast	carcinoma	p.M192I	Substitution - Missense	1:64869382-64869382,	PATHOGENIC	0.99373	28481359
JAK1	6190	COSM6924985,	thyroid	carcinoma	p.S1062F	Substitution - Missense	1:64836171-64836171,	PATHOGENIC	0.99318	28481359
JAK1	6190	COSM6973448,	upper_aerodigestive_tract	carcinoma	p.P836S	Substitution - Missense	1:64841499-64841499,	PATHOGENIC	0.99254	28481359
JAK1	6190	COSM6909143,	breast	carcinoma	p.L1010R	Substitution - Missense	1:64838043-64838043,	PATHOGENIC	0.99252	28481359
JAK1	6190	COSM6909143,	breast	carcinoma	p.L1010R	Substitution - Missense	1:64838043-64838043,	PATHOGENIC	0.99252	28481359
JAK1	6190	COSM6924117,	breast	carcinoma	p.E864*	Substitution - Nonsense	1:64841304-64841304,	PATHOGENIC	0.9925	28481359
JAK1	6190	COSM6967874,	lung	carcinoma	p.H934Y	Substitution - Missense	1:64839645-64839645,	PATHOGENIC	0.99238	28481359
JAK1	6190	COSM240269,	thyroid	carcinoma	p.E188K	Substitution - Missense	1:64869396-64869396,	PATHOGENIC	0.99237	28481359
JAK1	6190	COSM6984305,	endometrium	carcinoma	p.E587K	Substitution - Missense	1:64847672-64847672,	PATHOGENIC	0.99232	28481359
JAK1	6190	COSM6970130,	lung	carcinoma	p.?	Unknown	1:64836096-64836096,	PATHOGENIC	0.99223	28481359
JAK1	6190	COSM6914980,	lung	carcinoma	p.P861T	Substitution - Missense	1:64841313-64841313,	PATHOGENIC	0.99174	28481359
JAK1	6190	COSM6962551,	lung	carcinoma	p.N187S	Substitution - Missense	1:64869398-64869398,	PATHOGENIC	0.99162	28481359
JAK1	6190	COSM6976968,	lung	carcinoma	p.D1003H	Substitution - Missense	1:64838065-64838065,	PATHOGENIC	0.99161	28481359
JAK1	6190	COSM1602623,	liver	carcinoma	p.L910P	Substitution - Missense	1:64839716-64839716,	PATHOGENIC	0.99154	28481359
JAK1	6190	COSM4169978,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G1097D	Substitution - Missense	1:64835475-64835475,	PATHOGENIC	0.99095	27369867
JAK1	6190	COSM4169978,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G1097D	Substitution - Missense	1:64835475-64835475,	PATHOGENIC	0.99095	24345752
JAK1	6190	COSM6849677,	breast	carcinoma	p.S1043I	Substitution - Missense	1:64837944-64837944,	PATHOGENIC	0.99091	28270497
JAK1	6190	COSM6920853,	breast	carcinoma	p.R1007T	Substitution - Missense	1:64838052-64838052,	PATHOGENIC	0.99062	28481359
JAK1	6190	COSM6935151,	endometrium	carcinoma	p.D844Y	Substitution - Missense	1:64841475-64841475,	PATHOGENIC	0.99	28481359
JAK1	6190	COSM6926101,	breast	carcinoma	p.R843I	Substitution - Missense	1:64841477-64841477,	PATHOGENIC	0.99	28481359
JAK1	6190	COSM6921717,	central_nervous_system	glioma	p.N241Y	Substitution - Missense	1:64867135-64867135,	PATHOGENIC	0.98983	28481359
JAK1	6190	COSM6911938,	large_intestine	carcinoma	p.E609*	Substitution - Nonsense	1:64847606-64847606,	PATHOGENIC	0.98916	28481359
JAK1	6190	COSM6957906,	upper_aerodigestive_tract	carcinoma	p.L820Q	Substitution - Missense	1:64841546-64841546,	PATHOGENIC	0.98905	28481359
JAK1	6190	COSM6979549,	large_intestine	carcinoma	p.R1002Q	Substitution - Missense	1:64838067-64838067,	PATHOGENIC	0.98881	28481359
JAK1	6190	COSM4990582,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P960S	Substitution - Missense	1:64838554-64838554,	PATHOGENIC	0.98873	28410228
JAK1	6190	COSM4990582,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P960S	Substitution - Missense	1:64838554-64838554,	PATHOGENIC	0.98873	24056718
JAK1	6190	COSM4990581,	skin	carcinoma	p.P960L	Substitution - Missense	1:64838553-64838553,	PATHOGENIC	0.98873	25589618
JAK1	6190	COSM4990582,	skin	carcinoma	p.P960S	Substitution - Missense	1:64838554-64838554,	PATHOGENIC	0.98873	25589618
JAK1	6190	COSM6917601,	skin	malignant_melanoma	p.Y967H	Substitution - Missense	1:64838533-64838533,	PATHOGENIC	0.9879	28481359
JAK1	6190	COSM6907136,	urinary_tract	carcinoma	p.E287Q	Substitution - Missense	1:64866997-64866997,	PATHOGENIC	0.98781	29420467
JAK1	6190	COSM6947308,	prostate	carcinoma	p.Q1143*	Substitution - Nonsense	1:64834600-64834600,	PATHOGENIC	0.98774	28481359
JAK1	6190	COSM6946070,	large_intestine	carcinoma	p.?	Unknown	1:64850911-64850911,	PATHOGENIC	0.9877	28481359
JAK1	6190	COSM6946068,	large_intestine	carcinoma	p.G1148*	Substitution - Nonsense	1:64834585-64834585,	PATHOGENIC	0.98739	28481359
JAK1	6190	COSM6935150,	endometrium	carcinoma	p.I928F	Substitution - Missense	1:64839663-64839663,	PATHOGENIC	0.98709	28481359
JAK1	6190	COSM6942878,	lung	carcinoma	p.E662Q	Substitution - Missense	1:64846652-64846652,	PATHOGENIC	0.98705	28481359
JAK1	6190	COSM6958244,	lung	carcinoma	p.E913K	Substitution - Missense	1:64839708-64839708,	PATHOGENIC	0.98699	28481359
JAK1	6190	COSM6981889,	endometrium	carcinoma	p.E1133*	Substitution - Nonsense	1:64834630-64834630,	PATHOGENIC	0.9868	28481359
JAK1	6190	COSM2239136,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y654F	Substitution - Missense	1:64846675-64846675,	PATHOGENIC	0.98661	26415585
JAK1	6190	COSM6919715,	soft_tissue	leiomyosarcoma	p.?	Unknown	1:64838105-64838105,	PATHOGENIC	0.98616	28481359
JAK1	6190	COSM6954161,	large_intestine	carcinoma	p.K267E	Substitution - Missense	1:64867057-64867057,	PATHOGENIC	0.98611	28481359
JAK1	6190	COSM5705527,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T901A	Substitution - Missense	1:64839744-64839744,	PATHOGENIC	0.98589	26437031
JAK1	6190	COSM6944124,	urinary_tract	carcinoma	p.S1080L	Substitution - Missense	1:64836117-64836117,	PATHOGENIC	0.9854	28481359
JAK1	6190	COSM6944124,	urinary_tract	carcinoma	p.S1080L	Substitution - Missense	1:64836117-64836117,	PATHOGENIC	0.9854	28481359
JAK1	6190	COSM6948223,	central_nervous_system	glioma	p.E850K	Substitution - Missense	1:64841457-64841457,	PATHOGENIC	0.98504	28481359
JAK1	6190	COSM133112,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D604Y	Substitution - Missense	1:64847621-64847621,	PATHOGENIC	0.9847	21880637
JAK1	6190	COSM6444841,	endometrium	carcinoma	p.E447*	Substitution - Nonsense	1:64857775-64857775,	PATHOGENIC	0.9847	27159395
JAK1	6190	COSM911558,	endometrium	carcinoma	p.E668*	Substitution - Nonsense	1:64845626-64845626,	PATHOGENIC	0.98466	27159395
JAK1	6190	COSM6938433,	large_intestine	carcinoma	p.E706K	Substitution - Missense	1:64844889-64844889,	PATHOGENIC	0.98418	28481359
JAK1	6190	COSM6953254,	urinary_tract	carcinoma	p.E849K	Substitution - Missense	1:64841460-64841460,	PATHOGENIC	0.98371	28481359
JAK1	6190	COSM1343910,	large_intestine	carcinoma	p.A449T	Substitution - Missense	1:64857769-64857769,	PATHOGENIC	0.98342	28481359
JAK1	6190	COSM6196690,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A639G	Substitution - Missense	1:64846720-64846720,	PATHOGENIC	0.98342	28410228
JAK1	6190	COSM6933526,	lung	carcinoma	p.?	Unknown	1:64844217-64844217,	PATHOGENIC	0.98327	28481359
JAK1	6190	COSM48448,	lung	carcinoma	p.M828I	Substitution - Missense	1:64841521-64841521,	PATHOGENIC	0.98321	18948947
JAK1	6190	COSM6917248,	breast	carcinoma	p.Q986*	Substitution - Nonsense	1:64838476-64838476,	PATHOGENIC	0.98228	28481359
JAK1	6190	COSM6944304,	NS	carcinoma	p.T558A	Substitution - Missense	1:64850887-64850887,	PATHOGENIC	0.98196	28481359
JAK1	6190	COSM4606338,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1012G	Substitution - Missense	1:64838037-64838037,	PATHOGENIC	0.98194	25430085
JAK1	6190	COSM4606338,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1012G	Substitution - Missense	1:64838037-64838037,	PATHOGENIC	0.98194	22237106
JAK1	6190	COSM6196689,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S646P	Substitution - Missense	1:64846700-64846700,	PATHOGENIC	0.98155	28410228
JAK1	6190	COSM6196689,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S646P	Substitution - Missense	1:64846700-64846700,	PATHOGENIC	0.98155	28410228
JAK1	6190	COSM6196689,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S646P	Substitution - Missense	1:64846700-64846700,	PATHOGENIC	0.98155	28410228
JAK1	6190	COSM41754,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R879C	Substitution - Missense	1:64841259-64841259,	PATHOGENIC	0.98147	25595890
JAK1	6190	COSM41754,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R879C	Substitution - Missense	1:64841259-64841259,	PATHOGENIC	0.98147	18362173
JAK1	6190	COSM6960756,	stomach	carcinoma	p.V746A	Substitution - Missense	1:64844768-64844768,	PATHOGENIC	0.9803	28481359
JAK1	6190	COSM6960756,	stomach	carcinoma	p.V746A	Substitution - Missense	1:64844768-64844768,	PATHOGENIC	0.9803	28481359
JAK1	6190	COSM6946069,	large_intestine	carcinoma	p.D728N	Substitution - Missense	1:64844823-64844823,	PATHOGENIC	0.98003	28481359
JAK1	6190	COSM6974834,	large_intestine	carcinoma	p.M477T	Substitution - Missense	1:64857684-64857684,	PATHOGENIC	0.97983	28481359
JAK1	6190	COSM6930206,	skin	malignant_melanoma	p.I444V	Substitution - Missense	1:64860109-64860109,	PATHOGENIC	0.97959	28481359
JAK1	6190	COSM96541,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703T	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97928	21390130
JAK1	6190	COSM96541,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703T	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97928	21390130
JAK1	6190	COSM6958530,	skin	malignant_melanoma	p.?	Unknown	1:64845512-64845512,	PATHOGENIC	0.97882	28481359
JAK1	6190	COSM305942,	liver	carcinoma	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	28481359
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	26437031
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	22237106
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	27288520
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	26437031
JAK1	6190	COSM305942,	liver	carcinoma	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	28481359
JAK1	6190	COSM305942,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S703I	Substitution - Missense	1:64845520-64845520,	PATHOGENIC	0.97872	23733339
JAK1	6190	COSM6974430,	upper_aerodigestive_tract	carcinoma	p.E637Q	Substitution - Missense	1:64846727-64846727,	PATHOGENIC	0.97812	28481359
JAK1	6190	COSM6907429,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M824L	Substitution - Missense	1:64841535-64841535,	PATHOGENIC	0.97667	24056718
JAK1	6190	COSM6995445,	ovary	germ_cell_tumour	p.K580E	Substitution - Missense	1:64850821-64850821,	PATHOGENIC	0.97638	28954785
JAK1	6190	COSM41757,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.V658F	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.97549	21680795
JAK1	6190	COSM41757,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.V658F	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.97549	18559588
JAK1	6190	COSM41757,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.V658F	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.97549	18559588
JAK1	6190	COSM41757,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.V658F	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.97549	18559588
JAK1	6190	COSM312102,	lung	carcinoma	p.K140*	Substitution - Nonsense	1:64873435-64873435,	PATHOGENIC	0.97521	22941188
JAK1	6190	COSM94556,	penis	carcinoma	p.E637K	Substitution - Missense	1:64846727-64846727,	PATHOGENIC	0.97454	28481359
JAK1	6190	COSM94556,	breast	carcinoma	p.E637K	Substitution - Missense	1:64846727-64846727,	PATHOGENIC	0.97454	20668451
JAK1	6190	COSM6920980,	prostate	carcinoma	p.R826C	Substitution - Missense	1:64841529-64841529,	PATHOGENIC	0.97419	28481359
JAK1	6190	COSM6920980,	prostate	carcinoma	p.R826C	Substitution - Missense	1:64841529-64841529,	PATHOGENIC	0.97419	28481359
JAK1	6190	COSM5989716,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M679L	Substitution - Missense	1:64845593-64845593,	PATHOGENIC	0.97378	26648538
JAK1	6190	COSM6973687,	prostate	carcinoma	p.C424F	Substitution - Missense	1:64860168-64860168,	PATHOGENIC	0.97377	28481359
JAK1	6190	COSM5047136,	oesophagus	carcinoma	p.W363R	Substitution - Missense	1:64864876-64864876,	PATHOGENIC	0.97357	24686850
JAK1	6190	COSM2239144,	breast	carcinoma	p.A428P	Substitution - Missense	1:64860157-64860157,	PATHOGENIC	0.97355	28481359
JAK1	6190	COSM6494356,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L1053V	Substitution - Missense	1:64836199-64836199,	PATHOGENIC	0.97193	27534895
JAK1	6190	COSM6494356,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L1053V	Substitution - Missense	1:64836199-64836199,	PATHOGENIC	0.97193	27534895
JAK1	6190	COSM7002460,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.V658I	Substitution - Missense	1:64846664-64846664,	PATHOGENIC	0.9713	28550193
JAK1	6190	COSM6910406,	testis	germ_cell_tumour	p.T478A	Substitution - Missense	1:64857682-64857682,	PATHOGENIC	0.97103	28481359
JAK1	6190	COSM5762889,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I597M	Substitution - Missense	1:64847640-64847640,	PATHOGENIC	0.97036	27127180
JAK1	6190	COSM6928863,	central_nervous_system	glioma	p.V1011I	Substitution - Missense	1:64838041-64838041,	PATHOGENIC	0.96941	28481359
JAK1	6190	COSM6934408,	urinary_tract	carcinoma	p.R414Q	Substitution - Missense	1:64860198-64860198,	PATHOGENIC	0.9693	28481359
JAK1	6190	COSM911571,	skin	carcinoma	p.R174*	Substitution - Nonsense	1:64869438-64869438,	PATHOGENIC	0.96928	28481359
JAK1	6190	COSM911571,	endometrium	carcinoma	p.R174*	Substitution - Nonsense	1:64869438-64869438,	PATHOGENIC	0.96928	25233892
JAK1	6190	COSM911571,	oesophagus	carcinoma	p.R174*	Substitution - Nonsense	1:64869438-64869438,	PATHOGENIC	0.96928	28481359
JAK1	6190	COSM911571,	breast	carcinoma	p.R174*	Substitution - Nonsense	1:64869438-64869438,	PATHOGENIC	0.96928	28481359
JAK1	6190	COSM6948457,	urinary_tract	carcinoma	p.V1124I	Substitution - Missense	1:64834657-64834657,	PATHOGENIC	0.96902	28481359
JAK1	6190	COSM6962781,	central_nervous_system	glioma	p.D410N	Substitution - Missense	1:64860211-64860211,	PATHOGENIC	0.96868	28481359
JAK1	6190	COSM6930134,	prostate	carcinoma	p.V651M	Substitution - Missense	1:64846685-64846685,	PATHOGENIC	0.96804	28481359
JAK1	6190	COSM133113,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.F734L	Substitution - Missense	1:64844803-64844803,	PATHOGENIC	0.96757	21880637
JAK1	6190	COSM5990834,	liver	other	p.A723D	Substitution - Missense	1:64844837-64844837,	PATHOGENIC	0.96745	24735922
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	22425895
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	18362173
JAK1	6190	COSM41751,	urinary_tract	carcinoma	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	28481359
JAK1	6190	COSM41751,	endometrium	carcinoma	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	28481359
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	22425895
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	25854815
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	18362173
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	22425895
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	25595890
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	18362173
JAK1	6190	COSM41751,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H	Substitution - Missense	1:64844834-64844834,	PATHOGENIC	0.96737	18362173
JAK1	6190	COSM4990585,	skin	carcinoma	p.T470I	Substitution - Missense	1:64857705-64857705,	PATHOGENIC	0.96605	25589618
JAK1	6190	COSM303855,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S646F	Substitution - Missense	1:64846699-64846699,	PATHOGENIC	0.96601	21680795
JAK1	6190	COSM6986431,	lung	carcinoma	p.K218N	Substitution - Missense	1:64867202-64867202,	PATHOGENIC	0.96558	28481359
JAK1	6190	COSM464865,	endometrium	carcinoma	p.A984V	Substitution - Missense	1:64838481-64838481,	PATHOGENIC	0.96393	28481359
JAK1	6190	COSM1717657,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.I377K	Substitution - Missense	1:64864833-64864833,	PATHOGENIC	0.96352	23603912
JAK1	6190	COSM6977897,	large_intestine	carcinoma	p.T745M	Substitution - Missense	1:64844771-64844771,	PATHOGENIC	0.96303	28481359
JAK1	6190	COSM6936372,	lung	carcinoma	p.R804T	Substitution - Missense	1:64841594-64841594,	PATHOGENIC	0.95963	28481359
JAK1	6190	COSM5609183,	skin	malignant_melanoma	p.P131L	Substitution - Missense	1:64873461-64873461,	PATHOGENIC	0.95943	26343386
JAK1	6190	COSM95619,	breast	carcinoma	p.W467*	Substitution - Nonsense	1:64857713-64857713,	PATHOGENIC	0.95846	20668451
JAK1	6190	COSM41759,	lung	carcinoma	p.T782M	Substitution - Missense	1:64844122-64844122,	PATHOGENIC	0.95841	18559588
JAK1	6190	COSM5609180,	skin	malignant_melanoma	p.L150F	Substitution - Missense	1:64873405-64873405,	PATHOGENIC	0.95839	26343386
JAK1	6190	COSM6936858,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L403W	Substitution - Missense	1:64860231-64860231,	PATHOGENIC	0.95676	28481359
JAK1	6190	COSM5415928,	large_intestine	carcinoma	p.V427M	Substitution - Missense	1:64860160-64860160,	PATHOGENIC	0.95621	28481359
JAK1	6190	COSM5415928,	endometrium	carcinoma	p.V427M	Substitution - Missense	1:64860160-64860160,	PATHOGENIC	0.95621	25233892
JAK1	6190	COSM5095534,	thymus	thymic_carcinoma	p.?	Unknown	1:64883276-64883276,	PATHOGENIC	0.95506	24974848
JAK1	6190	COSM5745651,	large_intestine	carcinoma	p.R1113C	Substitution - Missense	1:64835428-64835428,	PATHOGENIC	0.95315	28481359
JAK1	6190	COSM4990583,	skin	carcinoma	p.E751K	Substitution - Missense	1:64844754-64844754,	PATHOGENIC	0.95268	25589618
JAK1	6190	COSM6928864,	central_nervous_system	glioma	p.S574N	Substitution - Missense	1:64850838-64850838,	PATHOGENIC	0.95225	28481359
JAK1	6190	COSM6924118,	lung	carcinoma	p.W777C	Substitution - Missense	1:64844136-64844136,	PATHOGENIC	0.95174	28481359
JAK1	6190	COSM6924118,	breast	carcinoma	p.W777C	Substitution - Missense	1:64844136-64844136,	PATHOGENIC	0.95174	28481359
JAK1	6190	COSM911551,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.F958C	Substitution - Missense	1:64838559-64838559,	PATHOGENIC	0.95043	26437031
JAK1	6190	COSM3734693,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R659C	Substitution - Missense	1:64846661-64846661,	PATHOGENIC	0.95028	24497536
JAK1	6190	COSM6957258,	penis	carcinoma	p.N497H	Substitution - Missense	1:64855668-64855668,	PATHOGENIC	0.94991	28481359
JAK1	6190	COSM5945903,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y652N	Substitution - Missense	1:64846682-64846682,	PATHOGENIC	0.94983	26773734
JAK1	6190	COSM6981134,	endometrium	carcinoma	p.R873C	Substitution - Missense	1:64841277-64841277,	PATHOGENIC	0.94937	28481359
JAK1	6190	COSM6961253,	upper_aerodigestive_tract	carcinoma	p.I756F	Substitution - Missense	1:64844201-64844201,	PATHOGENIC	0.94935	28481359
JAK1	6190	COSM6910167,	lung	carcinoma	p.V261L	Substitution - Missense	1:64867075-64867075,	PATHOGENIC	0.94887	28481359
JAK1	6190	COSM6982246,	endometrium	carcinoma	p.C481*	Substitution - Nonsense	1:64857671-64857671,	PATHOGENIC	0.94838	28481359
JAK1	6190	COSM6978650,	breast	carcinoma	p.L235V	Substitution - Missense	1:64867153-64867153,	PATHOGENIC	0.94816	28481359
JAK1	6190	COSM6978491,	endometrium	carcinoma	p.V1101I	Substitution - Missense	1:64835464-64835464,	PATHOGENIC	0.94775	28481359
JAK1	6190	COSM911575,	large_intestine	carcinoma	p.?	Unknown	1:64883276-64883276,	PATHOGENIC	0.94766	28481359
JAK1	6190	COSM6938432,	large_intestine	carcinoma	p.D775N	Substitution - Missense	1:64844144-64844144,	PATHOGENIC	0.94761	28481359
JAK1	6190	COSM6909299,	lung	carcinoma	p.E58K	Substitution - Missense	1:64883310-64883310,	PATHOGENIC	0.94758	28481359
JAK1	6190	COSM6978873,	kidney	carcinoma	p.M462I	Substitution - Missense	1:64857728-64857728,	PATHOGENIC	0.9473	28481359
JAK1	6190	COSM6914226,	skin	carcinoma	p.R454W	Substitution - Missense	1:64857754-64857754,	PATHOGENIC	0.94625	28481359
JAK1	6190	COSM6915320,	skin	carcinoma	p.?	Unknown	1:64844216-64844216,	PATHOGENIC	0.94584	28481359
JAK1	6190	COSM6914547,	prostate	carcinoma	p.R128C	Substitution - Missense	1:64873471-64873471,	PATHOGENIC	0.9431	28481359
JAK1	6190	COSM6913928,	salivary_gland	carcinoma	p.L1104F	Substitution - Missense	1:64835455-64835455,	PATHOGENIC	0.94304	28481359
JAK1	6190	COSM911545,	endometrium	carcinoma	p.R1139W	Substitution - Missense	1:64834612-64834612,	PATHOGENIC	0.9422	28481359
JAK1	6190	COSM5609181,	skin	malignant_melanoma	p.Q1098Q	Substitution - coding silent	1:64835471-64835471,	PATHOGENIC	0.9415	26343386
JAK1	6190	COSM1667603,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E897K	Substitution - Missense	1:64839756-64839756,	PATHOGENIC	0.94138	25595890
JAK1	6190	COSM5047430,	oesophagus	carcinoma	p.E1123Q	Substitution - Missense	1:64835398-64835398,	PATHOGENIC	0.93831	24686850
JAK1	6190	COSM5415927,	large_intestine	carcinoma	p.E791K	Substitution - Missense	1:64844096-64844096,	PATHOGENIC	0.93761	28481359
JAK1	6190	COSM5415927,	endometrium	carcinoma	p.E791K	Substitution - Missense	1:64844096-64844096,	PATHOGENIC	0.93761	25233892
JAK1	6190	COSM41776,	liver	carcinoma	p.V645F	Substitution - Missense	1:64846703-64846703,	PATHOGENIC	0.93606	19239328
JAK1	6190	COSM6922191,	soft_tissue	gastrointestinal_stromal_tumour	p.R997Q	Substitution - Missense	1:64838082-64838082,	PATHOGENIC	0.93595	28481359
JAK1	6190	COSM1579122,	lung	carcinoma	p.Q207L	Substitution - Missense	1:64869338-64869338,	PATHOGENIC	0.93504	28481359
JAK1	6190	COSM6952092,	large_intestine	carcinoma	p.D796Y	Substitution - Missense	1:64844081-64844081,	PATHOGENIC	0.93421	28481359
JAK1	6190	COSM6959923,	lung	carcinoma	p.D388N	Substitution - Missense	1:64864801-64864801,	PATHOGENIC	0.93105	28481359
JAK1	6190	COSM6919097,	endometrium	carcinoma	p.L702V	Substitution - Missense	1:64845524-64845524,	PATHOGENIC	0.93092	28481359
JAK1	6190	COSM6964229,	prostate	carcinoma	p.R549*	Substitution - Nonsense	1:64855512-64855512,	PATHOGENIC	0.92845	28481359
JAK1	6190	COSM6981475,	large_intestine	carcinoma	p.R659S	Substitution - Missense	1:64846661-64846661,	PATHOGENIC	0.92761	28481359
JAK1	6190	COSM6221446,	prostate	carcinoma	p.V656I	Substitution - Missense	1:64846670-64846670,	PATHOGENIC	0.92593	28481359
JAK1	6190	COSM6221446,	large_intestine	carcinoma	p.V656I	Substitution - Missense	1:64846670-64846670,	PATHOGENIC	0.92593	28481359
JAK1	6190	COSM6006332,	skin	adnexal_tumour	p.E1123K	Substitution - Missense	1:64835398-64835398,	PATHOGENIC	0.91943	27287813
JAK1	6190	COSM1645298,	large_intestine	carcinoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	23700467
JAK1	6190	COSM1645298,	soft_tissue	liposarcoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	28481359
JAK1	6190	COSM1645298,	oesophagus	carcinoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	28481359
JAK1	6190	COSM1645298,	large_intestine	carcinoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	23700467
JAK1	6190	COSM1645298,	soft_tissue	liposarcoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	29420467
JAK1	6190	COSM1645298,	large_intestine	carcinoma	p.R532H	Substitution - Missense	1:64855562-64855562,	PATHOGENIC	0.91845	28481359
JAK1	6190	COSM6949371,	central_nervous_system	glioma	p.E1029K	Substitution - Missense	1:64837987-64837987,	PATHOGENIC	0.91615	28481359
JAK1	6190	COSM6949371,	breast	carcinoma	p.E1029K	Substitution - Missense	1:64837987-64837987,	PATHOGENIC	0.91615	28481359
JAK1	6190	COSM5878734,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683T	Substitution - Missense	1:64845580-64845580,	PATHOGENIC	0.91342	27288520
JAK1	6190	COSM6964228,	prostate	carcinoma	p.R577W	Substitution - Missense	1:64850830-64850830,	PATHOGENIC	0.90962	28481359
JAK1	6190	COSM41758,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L783F	Substitution - Missense	1:64844120-64844120,	PATHOGENIC	0.90957	18559588
JAK1	6190	COSM6958243,	lung	carcinoma	p.G915E	Substitution - Missense	1:64839701-64839701,	PATHOGENIC	0.90925	28481359
JAK1	6190	COSM6957794,	large_intestine	carcinoma	p.K797R	Substitution - Missense	1:64844077-64844077,	PATHOGENIC	0.90854	28481359
JAK1	6190	COSM5574248,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L710V	Substitution - Missense	1:64844877-64844877,	PATHOGENIC	0.90792	26415585
JAK1	6190	COSM3741347,	upper_aerodigestive_tract	carcinoma	p.R724C	Substitution - Missense	1:64844835-64844835,	PATHOGENIC	0.90448	28581676
JAK1	6190	COSM6948224,	central_nervous_system	glioma	p.S518N	Substitution - Missense	1:64855604-64855604,	PATHOGENIC	0.90374	28481359
JAK1	6190	COSM4990586,	skin	carcinoma	p.K204N	Substitution - Missense	1:64869346-64869346,	PATHOGENIC	0.90302	25589618
JAK1	6190	COSM911557,	salivary_gland	carcinoma	p.R755*	Substitution - Nonsense	1:64844204-64844204,	PATHOGENIC	0.90015	28481359
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	soft_tissue	haemangioblastoma	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	25589003
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	soft_tissue	haemangioblastoma	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	25589003
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	soft_tissue	haemangioblastoma	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	25589003
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM5020680,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.K1032K	Substitution - coding silent	1:64837976-64837976,	PATHOGENIC	0.89988	27534895
JAK1	6190	COSM6951533,	breast	carcinoma	p.R237S	Substitution - Missense	1:64867145-64867145,	PATHOGENIC	0.89966	28481359
JAK1	6190	COSM6937352,	lung	carcinoma	p.H434Y	Substitution - Missense	1:64860139-64860139,	PATHOGENIC	0.89795	28481359
JAK1	6190	COSM41775,	liver	carcinoma	p.Q644H	Substitution - Missense	1:64846704-64846704,	PATHOGENIC	0.89517	19239328
JAK1	6190	COSM6918599,	skin	carcinoma	p.S367F	Substitution - Missense	1:64864863-64864863,	PATHOGENIC	0.89424	28481359
JAK1	6190	COSM5754489,	central_nervous_system	glioma	p.E337K	Substitution - Missense	1:64864954-64864954,	PATHOGENIC	0.89346	28481359
JAK1	6190	COSM6494363,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L4V	Substitution - Missense	1:64883472-64883472,	PATHOGENIC	0.88732	27534895
JAK1	6190	COSM6494363,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L4V	Substitution - Missense	1:64883472-64883472,	PATHOGENIC	0.88732	27534895
JAK1	6190	COSM6957257,	penis	carcinoma	p.S961L	Substitution - Missense	1:64838550-64838550,	PATHOGENIC	0.88641	28481359
JAK1	6190	COSM48449,	lung	carcinoma	p.D660H	Substitution - Missense	1:64846658-64846658,	PATHOGENIC	0.88497	18948947
JAK1	6190	COSM6948112,	urinary_tract	carcinoma	p.M202I	Substitution - Missense	1:64869352-64869352,	PATHOGENIC	0.88391	28481359
JAK1	6190	COSM5019856,	breast	carcinoma	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	28270497
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	soft_tissue	haemangioblastoma	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	25589003
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	soft_tissue	haemangioblastoma	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	25589003
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM5019856,	soft_tissue	haemangioblastoma	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	25589003
JAK1	6190	COSM5019856,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A699A	Substitution - coding silent	1:64845531-64845531,	PATHOGENIC	0.88371	27534895
JAK1	6190	COSM312103,	lung	carcinoma	p.E401D	Substitution - Missense	1:64860236-64860236,	PATHOGENIC	0.8834	22941188
JAK1	6190	COSM6951534,	breast	carcinoma	p.R232S	Substitution - Missense	1:64867160-64867160,	PATHOGENIC	0.87961	28481359
JAK1	6190	COSM6942686,	kidney	carcinoma	p.E765Q	Substitution - Missense	1:64844174-64844174,	PATHOGENIC	0.87667	28481359
JAK1	6190	COSM6935776,	central_nervous_system	glioma	p.M299I	Substitution - Missense	1:64866959-64866959,	PATHOGENIC	0.87046	28481359
JAK1	6190	COSM6977408,	NS	malignant_melanoma	p.L720F	Substitution - Missense	1:64844847-64844847,	PATHOGENIC	0.86774	28481359
JAK1	6190	COSM4605021,	upper_aerodigestive_tract	carcinoma	p.Q980H	Substitution - Missense	1:64838492-64838492,	PATHOGENIC	0.85671	25056374
JAK1	6190	COSM4990587,	skin	carcinoma	p.G53E	Substitution - Missense	1:64883324-64883324,	PATHOGENIC	0.85043	25589618
JAK1	6190	COSM6941120,	NS	carcinoma	p.S380F	Substitution - Missense	1:64864824-64864824,	PATHOGENIC	0.8445	28481359
JAK1	6190	COSM6941120,	NS	carcinoma	p.S380F	Substitution - Missense	1:64864824-64864824,	PATHOGENIC	0.8445	28481359
JAK1	6190	COSM6956513,	endometrium	carcinoma	p.R577Q	Substitution - Missense	1:64850829-64850829,	PATHOGENIC	0.84071	28481359
JAK1	6190	COSM1717658,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S71C	Substitution - Missense	1:64879142-64879142,	PATHOGENIC	0.84022	23603912
JAK1	6190	COSM6922928,	central_nervous_system	glioma	p.T263M	Substitution - Missense	1:64867068-64867068,	PATHOGENIC	0.83214	28481359
JAK1	6190	COSM1717659,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.W564C	Substitution - Missense	1:64850867-64850867,	PATHOGENIC	0.82757	23603912
JAK1	6190	COSM6961824,	pancreas	carcinoid-endocrine_tumour	p.V409I	Substitution - Missense	1:64860214-64860214,	PATHOGENIC	0.82433	28481359
JAK1	6190	COSM6981890,	endometrium	carcinoma	p.F78S	Substitution - Missense	1:64879121-64879121,	PATHOGENIC	0.81591	28481359
JAK1	6190	COSM6941119,	NS	carcinoma	p.E1150K	Substitution - Missense	1:64834579-64834579,	PATHOGENIC	0.81482	28481359
JAK1	6190	COSM6941119,	NS	carcinoma	p.E1150K	Substitution - Missense	1:64834579-64834579,	PATHOGENIC	0.81482	28481359
JAK1	6190	COSM6959073,	urinary_tract	carcinoma	p.E354K	Substitution - Missense	1:64864903-64864903,	PATHOGENIC	0.81069	28481359
JAK1	6190	COSM6969013,	thyroid	carcinoma	p.E54Q	Substitution - Missense	1:64883322-64883322,	PATHOGENIC	0.80859	28481359
JAK1	6190	COSM6959387,	central_nervous_system	glioma	p.D246N	Substitution - Missense	1:64867120-64867120,	PATHOGENIC	0.80319	28481359
JAK1	6190	COSM1645390,	large_intestine	carcinoma	p.S367C	Substitution - Missense	1:64864863-64864863,	PATHOGENIC	0.80307	23700467
JAK1	6190	COSM6945203,	autonomic_ganglia	neuroblastoma	p.F779L	Substitution - Missense	1:64844130-64844130,	PATHOGENIC	0.80144	28481359
JAK1	6190	COSM6938450,	large_intestine	carcinoma	p.T863N	Substitution - Missense	1:64841306-64841306,	PATHOGENIC	0.79251	28481359
JAK1	6190	COSM5019852,	skin	malignant_melanoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	26343386
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	soft_tissue	haemangioblastoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	25589003
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	breast	carcinoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	28270497
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	soft_tissue	haemangioblastoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	25589003
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	27534895
JAK1	6190	COSM5019852,	soft_tissue	haemangioblastoma	p.I530I	Substitution - coding silent	1:64855567-64855567,	PATHOGENIC	0.79168	25589003
JAK1	6190	COSM6923433,	large_intestine	carcinoma	p.R343W	Substitution - Missense	1:64864936-64864936,	PATHOGENIC	0.7879	28481359
JAK1	6190	COSM6923433,	central_nervous_system	glioma	p.R343W	Substitution - Missense	1:64864936-64864936,	PATHOGENIC	0.7879	28481359
JAK1	6190	COSM5415930,	endometrium	carcinoma	p.E54*	Substitution - Nonsense	1:64883322-64883322,	PATHOGENIC	0.76595	25233892
JAK1	6190	COSM6911729,	urinary_tract	carcinoma	p.E400K	Substitution - Missense	1:64860241-64860241,	PATHOGENIC	0.75386	28481359
JAK1	6190	COSM6936904,	skin	carcinoma	p.E54K	Substitution - Missense	1:64883322-64883322,	PATHOGENIC	0.74213	28481359
JAK1	6190	COSM96407,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.K648N	Substitution - Missense	1:64846692-64846692,	PATHOGENIC	0.73414	21551237
JAK1	6190	COSM6946968,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.E613K	Substitution - Missense	1:64847594-64847594,	PATHOGENIC	0.73371	28481359
JAK1	6190	COSM96408,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y652H	Substitution - Missense	1:64846682-64846682,	PATHOGENIC	0.71207	26773734
JAK1	6190	COSM96408,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Y652H	Substitution - Missense	1:64846682-64846682,	PATHOGENIC	0.71207	27288520
JAK1	6190	COSM96408,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y652H	Substitution - Missense	1:64846682-64846682,	PATHOGENIC	0.71207	21551237
JAK1	6190	COSM6930582,	skin	malignant_melanoma	p.R93C	Substitution - Missense	1:64879077-64879077,	NEUTRAL	0.46067	28481359
JAK1	6190	COSM6930582,	penis	carcinoma	p.R93C	Substitution - Missense	1:64879077-64879077,	NEUTRAL	0.46067	28481359
JAK1	6190	COSM6977127,	large_intestine	carcinoma	p.K606N	Substitution - Missense	1:64847613-64847613,	NEUTRAL	0.44893	28481359
JAK1	6190	COSM327049,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	1:64864978-64864978,	NEUTRAL	0.40938	22675565
JAK1	6190	COSM4604577,	upper_aerodigestive_tract	carcinoma	p.E614E	Substitution - coding silent	1:64847589-64847589,	NEUTRAL	0.39075	25056374
JAK1	6190	COSM5609182,	skin	malignant_melanoma	p.R577R	Substitution - coding silent	1:64850828-64850828,	NEUTRAL	0.36638	26343386
JAK1	6190	COSM1726762,	liver	carcinoma	p.S729C	Substitution - Missense	1:64844820-64844820,	NEUTRAL	0.33636	28481359
JAK1	6190	COSM1726762,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S729C	Substitution - Missense	1:64844820-64844820,	NEUTRAL	0.33636	25595890
JAK1	6190	COSM6494358,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R506H	Substitution - Missense	1:64855640-64855640,	NEUTRAL	0.33575	27534895
JAK1	6190	COSM6494358,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R506H	Substitution - Missense	1:64855640-64855640,	NEUTRAL	0.33575	27534895
JAK1	6190	COSM6929565,	testis	germ_cell_tumour	p.L105F	Substitution - Missense	1:64879041-64879041,	NEUTRAL	0.32996	28481359
JAK1	6190	COSM6973007,	large_intestine	carcinoma	p.R506S	Substitution - Missense	1:64855641-64855641,	NEUTRAL	0.31059	28481359
JAK1	6190	COSM6926296,	breast	carcinoma	p.G490A	Substitution - Missense	1:64855688-64855688,	NEUTRAL	0.30508	28481359
JAK1	6190	COSM6974196,	prostate	carcinoma	p.R69C	Substitution - Missense	1:64883277-64883277,	NEUTRAL	0.30447	28481359
JAK1	6190	COSM6946032,	breast	carcinoma	p.E83D	Substitution - Missense	1:64879105-64879105,	NEUTRAL	0.24838	28481359
JAK1	6190	COSM6005665,	prostate	carcinoma	p.L1108V	Substitution - Missense	1:64835443-64835443,	NEUTRAL	0.23588	20579941
JAK1	6190	COSM3491775,	skin	malignant_melanoma	p.S262S	Substitution - coding silent	1:64867070-64867070,	NEUTRAL	0.22978	26343386
JAK1	6190	COSM911565,	endometrium	carcinoma	p.S304L	Substitution - Missense	1:64866945-64866945,	NEUTRAL	0.21375	28481359
JAK1	6190	COSM911565,	urinary_tract	carcinoma	p.S304L	Substitution - Missense	1:64866945-64866945,	NEUTRAL	0.21375	28481359
JAK1	6190	COSM6920416,	large_intestine	carcinoma	p.V567I	Substitution - Missense	1:64850860-64850860,	NEUTRAL	0.20394	28481359
JAK1	6190	COSM6963786,	lung	carcinoma	p.G520V	Substitution - Missense	1:64855598-64855598,	NEUTRAL	0.13227	28481359
JAK1	6190	COSM6986310,	lung	carcinoma	p.R69H	Substitution - Missense	1:64879148-64879148,	NEUTRAL	0.12774	28481359
JAK1	6190	COSM6494360,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64869304-64869304,	NEUTRAL	0.11733	27534895
JAK1	6190	COSM6494360,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64869304-64869304,	NEUTRAL	0.11733	27534895
JAK1	6190	COSM6930065,	lung	carcinoma	p.Y568*	Substitution - Nonsense	1:64850855-64850855,	NEUTRAL	0.10206	28481359
JAK1	6190	COSM6986219,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.A862T	Substitution - Missense	1:64841310-64841310,	NEUTRAL	0.08403	28481359
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	soft_tissue	haemangioblastoma	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	25589003
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	soft_tissue	haemangioblastoma	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	25589003
JAK1	6190	COSM5020688,	soft_tissue	haemangioblastoma	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	25589003
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5020688,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A193A	Substitution - coding silent	1:64869379-64869379,	NEUTRAL	0.07827	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	soft_tissue	haemangioblastoma	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	25589003
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	soft_tissue	haemangioblastoma	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	25589003
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM5019756,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R659R	Substitution - coding silent	1:64846659-64846659,	NEUTRAL	0.07442	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751352,	soft_tissue	haemangioblastoma	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	25589003
JAK1	6190	COSM3751352,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S683S	Substitution - coding silent	1:64845579-64845579,	NEUTRAL	0.06602	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	breast	carcinoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	28270497
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	soft_tissue	haemangioblastoma	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	25589003
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM3751351,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P733P	Substitution - coding silent	1:64844806-64844806,	NEUTRAL	0.05995	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	breast	carcinoma	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	28270497
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	soft_tissue	haemangioblastoma	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	25589003
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	soft_tissue	haemangioblastoma	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	25589003
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5019905,	soft_tissue	haemangioblastoma	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	25589003
JAK1	6190	COSM5019905,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G182G	Substitution - coding silent	1:64869412-64869412,	NEUTRAL	0.04645	27534895
JAK1	6190	COSM5020590,	soft_tissue	haemangioblastoma	p.Y568Y	Substitution - coding silent	1:64850855-64850855,	NEUTRAL	0.044	25589003
JAK1	6190	COSM6494357,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T1036T	Substitution - coding silent	1:64837964-64837964,	NEUTRAL	0.02117	27534895
JAK1	6190	COSM6494357,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T1036T	Substitution - coding silent	1:64837964-64837964,	NEUTRAL	0.02117	27534895
JAK1	6190	COSM6494357,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T1036T	Substitution - coding silent	1:64837964-64837964,	NEUTRAL	0.02117	27534895
JAK1	6190	COSM4990584,	skin	carcinoma	p.P566P	Substitution - coding silent	1:64850861-64850861,	NEUTRAL	0.01125	25589618
JAK1	6190	COSM6494359,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S304S	Substitution - coding silent	1:64866944-64866944,	NEUTRAL	0.00972	27534895
JAK1	6190	COSM6494361,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T96T	Substitution - coding silent	1:64879066-64879066,	NEUTRAL	0.00358	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	breast	carcinoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	28270497
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	breast	carcinoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	28270497
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	soft_tissue	haemangioblastoma	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	25589003
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM5019821,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	1:64855705-64855705,	NEUTRAL	0.00342	27534895
JAK1	6190	COSM41842,	prostate	carcinoma	p.K142fs*26, p.L431fs*22, p.P430fs*2	Deletion - Frameshift, Insertion - Frameshift	1:64860149-64860150,	Info_not_available	Info_not_available	16102578
JAK1	6190	COSM41839,	soft_tissue	leiomyoma	p.G882E, p.M642I, p.S771C, p.V1045K, p.W1047G, p.Y463S	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	16474838
JAK1	6190	COSM41728,	central_nervous_system	glioma	p.L698L	Substitution - coding silent	Info_not_available	Info_not_available	Info_not_available	16618716
JAK1	6190	COSM41833,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T478S, p.V623A	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	18160671
JAK1	6190	COSM41756,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A634D, p.K204M, p.L653F, p.R879H, p.R879S, p.S512L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	18362173
JAK1	6190	COSM41760,	breast	carcinoma	p.H647Y	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	18559588
JAK1	6190	COSM48932,	lung	carcinoma	p.A428fs*25	Insertion - Frameshift	1:64860157-64860158,	Info_not_available	Info_not_available	18948947
JAK1	6190	COSM41831,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E966V, p.E966_K989del, p.S216fs*3	Deletion - Frameshift, Deletion - In frame, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19176360
JAK1	6190	COSM41763,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L624_R629>W, p.S646F, p.V658F	Complex - deletion inframe, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19470474
JAK1	6190	COSM41767,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R724H, p.R724Q, p.S512L, p.Y652H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19764985
JAK1	6190	COSM41763,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.V658F	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	19838194
JAK1	6190	COSM6005666,	prostate	carcinoma	p.K860fs*16, p.P430fs*2	Deletion - Frameshift	1:64860150-64860150,	Info_not_available	Info_not_available	20579941
JAK1	6190	COSM303810,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L624_R629>W	Complex - deletion inframe	1:64847546-64847560,	Info_not_available	Info_not_available	21680795
JAK1	6190	COSM133114,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1012fs*2	Insertion - Frameshift	1:64838039-64838040,	Info_not_available	Info_not_available	21880637
JAK1	6190	COSM4606337,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E1012_S1013insK	Insertion - In frame	Info_not_available	Info_not_available	Info_not_available	22237106
JAK1	6190	COSM41765,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Y652H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	22438252
JAK1	6190	COSM5945950,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F635_F636>F, p.I952V, p.N714fs*?, p.S383G	Complex - deletion inframe, Frameshift, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	23153540
JAK1	6190	COSM1666870,	urinary_tract	carcinoma	p.D660H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	23887298
JAK1	6190	COSM41756,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.L653F, p.R629_D630del	Deletion - In frame, Substitution - Missense	1:64847542-64847547,	Info_not_available	Info_not_available	24048415
JAK1	6190	COSM5049732,	oesophagus	carcinoma	p.G916fs*4	Deletion - Frameshift	1:64839700-64839700,	Info_not_available	Info_not_available	24686850
JAK1	6190	COSM4989844,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.C787F, p.K1026E, p.S646F, p.V658F, p.V658I	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25207766
JAK1	6190	COSM5415931,	ovary	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	25233892
JAK1	6190	COSM5024893,	breast	carcinoma	p.E223fs*11	Deletion - Frameshift	1:64867166-64867187,	Info_not_available	Info_not_available	25850943
JAK1	6190	COSM5752029,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E668fs*41, p.H649fs*60, p.I62fs*21, p.R724fs*2, p.T901fs*8, p.V1045fs*13, p.V658fs*51, p.Y652fs*57	Complex - frameshift, Insertion - Frameshift	1:64883298-64883298,	Info_not_available	Info_not_available	26206799
JAK1	6190	COSM41755,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm, lymphoid_neoplasm	p.R879H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27997762
JAK1	6190	COSM6842521,	haematopoietic_and_lymphoid_tissue	other	p.V310I	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28241173
JAK1	6190	COSM6196692,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N973K, p.Y652H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28410228
JAK1	6190	COSM6904599,	breast	carcinoma	p.H106Y, p.K795E	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28921573
JAK1	6190	COSM41728,	central_nervous_system, stomach	carcinoma, glioma	p.L698L, p.N719fs*7	Insertion - Frameshift, Substitution - coding silent	Info_not_available	Info_not_available	Info_not_available	Info_not_available
JAK1	6190	COSM6995426,	ovary	germ_cell_tumour	p.R20R	Substitution - coding silent	1:64883422-64883422,	Info_not_available	0.61898	28954785
JAK1	6190	COSM5029115,	breast	carcinoma	p.F1134L	Substitution - Missense	1:64834625-64834625,	Info_not_available	0.61706	22722193
JAK1	6190	COSM6494362,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D1031D, p.L42L	Substitution - coding silent	1:64883356-64883356,	Info_not_available	0.55416, .69495	27534895
JAK1	6190	COSM6981076,	NS, biliary_tract, bone, breast, endometrium, kidney, large_intestine, liver, lung, prostate, skin, soft_tissue, stomach, upper_aerodigestive_tract, urinary_tract	carcinoid-endocrine_tumour, carcinoma, chondrosarcoma, gastrointestinal_stromal_tumour, leiomyosarcoma, malignant_melanoma	p.A1006*, p.E1147fs?, p.E83K, p.G673fs*30, p.I943fs*33, p.K142fs*26, p.K345fs*32, p.K616delK, p.K860fs*16, p.L346fs*4, p.L431fs*22, p.L910S, p.N136fs*32, p.N339fs*2, p.N339fs*3, p.N357fs*20, p.P131L, p.P430fs*2, p.P861fs*4, p.Q387fs*66, p.Q644fs*57, p.R104W, p.R343Q, p.R835fs*12, p.S333fs*2, p.S524fs*12, p.T1095I, p.T1100fs*6, p.T868fs*8, p.V36M, p.Y422fs*11, p.Y89S	Complex - frameshift, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Substitution - Missense, Substitution - Nonsense	1:64883376-64883376,	Info_not_available	0.55012, .61989, .64445, .68886, Info_not_available	28481359