Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
CHUK	1974	COSM4989885,	skin	carcinoma	p.P190L	Substitution - Missense	10:100219128-100219128,	PATHOGENIC	0.998	25589618
CHUK	1974	COSM6164,	breast	carcinoma	p.?	Unknown	10:100207333-100207333,	PATHOGENIC	0.9974	15908952
CHUK	1974	COSM4989884,	skin	carcinoma	p.S266N	Substitution - Missense	10:100218718-100218718,	PATHOGENIC	0.99298	25589618
CHUK	1974	COSM20985,	central_nervous_system	glioma	p.?	Unknown	10:100202087-100202087,	PATHOGENIC	0.98603	Info_not_available
CHUK	1974	COSM20985,	central_nervous_system	glioma	p.?	Unknown	10:100202087-100202087,	PATHOGENIC	0.98603	Info_not_available
CHUK	1974	COSM4989887,	skin	carcinoma	p.?	Unknown	10:100222981-100222981,	PATHOGENIC	0.97984	25589618
CHUK	1974	COSM13312,	central_nervous_system	glioma	p.R133*	Substitution - Nonsense	10:100220665-100220665,	PATHOGENIC	0.97771	16618716
CHUK	1974	COSM13312,	large_intestine	carcinoma	p.R133*	Substitution - Nonsense	10:100220665-100220665,	PATHOGENIC	0.97771	Info_not_available
CHUK	1974	COSM13312,	central_nervous_system	glioma	p.R133*	Substitution - Nonsense	10:100220665-100220665,	PATHOGENIC	0.97771	16618716
CHUK	1974	COSM13312,	large_intestine	carcinoma	p.R133*	Substitution - Nonsense	10:100220665-100220665,	PATHOGENIC	0.97771	Info_not_available
CHUK	1974	COSM3751488,	soft_tissue	haemangioblastoma	p.S486S	Substitution - coding silent	10:100204555-100204555,	PATHOGENIC	0.94889	25589003
CHUK	1974	COSM3751488,	soft_tissue	haemangioblastoma	p.S486S	Substitution - coding silent	10:100204555-100204555,	PATHOGENIC	0.94889	25589003
CHUK	1974	COSM5703421,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q260*	Substitution - Nonsense	10:100218737-100218737,	PATHOGENIC	0.94437	26437031
CHUK	1974	COSM4989886,	skin	carcinoma	p.L152F	Substitution - Missense	10:100220608-100220608,	PATHOGENIC	0.93547	25589618
CHUK	1974	COSM3433515,	skin	carcinoma	p.S336L	Substitution - Missense	10:100209716-100209716,	PATHOGENIC	0.92668	25589618
CHUK	1974	COSM4989883,	skin	carcinoma	p.Q285*	Substitution - Nonsense	10:100218075-100218075,	PATHOGENIC	0.91687	25589618
CHUK	1974	COSM304613,	salivary_gland	carcinoma	p.R104*	Substitution - Nonsense	10:100222871-100222871,	PATHOGENIC	0.91389	27334835
CHUK	1974	COSM304613,	large_intestine	carcinoma	p.R104*	Substitution - Nonsense	10:100222871-100222871,	PATHOGENIC	0.91389	21892161
CHUK	1974	COSM4989882,	skin	carcinoma	p.I470I	Substitution - coding silent	10:100204603-100204603,	PATHOGENIC	0.91072	25589618
CHUK	1974	COSM147026,	soft_tissue	haemangioblastoma	p.V155A	Substitution - Missense	10:100220598-100220598,	PATHOGENIC	0.90637	25589003
CHUK	1974	COSM2057796,	central_nervous_system	glioma	p.R646fs*22	Deletion - Frameshift	10:100194022-100194022,	Info_not_available	Info_not_available	26487540
CHUK	1974	COSM5967328,	salivary_gland	carcinoma	p.C178fs*16	Deletion - Frameshift	10:100219301-100219302,	Info_not_available	Info_not_available	27334835