Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
FLNA	3754	COSM5730432,	breast	other	p.G1578C	Substitution - Missense	23:154358222-154358222,	PATHOGENIC	0.99024	26437033
FLNA	3754	COSM50267,	breast	carcinoma	p.D2581H	Substitution - Missense	23:154349377-154349377,	PATHOGENIC	0.98949	17932254
FLNA	3754	COSM5531313,	breast	other	p.P1244S	Substitution - Missense	23:154360065-154360065,	PATHOGENIC	0.98466	26437033
FLNA	3754	COSM5730741,	breast	other	p.G1236A	Substitution - Missense	23:154360088-154360088,	PATHOGENIC	0.98378	26437033
FLNA	3754	COSM5985501,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G2234E	Substitution - Missense	23:154352249-154352249,	PATHOGENIC	0.97425	26438511
FLNA	3754	COSM5985505,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P323L	Substitution - Missense	23:154366751-154366751,	PATHOGENIC	0.97408	26438511
FLNA	3754	COSM5985505,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P323L	Substitution - Missense	23:154366751-154366751,	PATHOGENIC	0.97408	26438511
FLNA	3754	COSM5730430,	breast	other	p.A1191T	Substitution - Missense	23:154360224-154360224,	PATHOGENIC	0.96834	26437033
FLNA	3754	COSM5730430,	breast	other	p.A1191T	Substitution - Missense	23:154360224-154360224,	PATHOGENIC	0.96834	26437033
FLNA	3754	COSM5730733,	breast	other	p.A1188T	Substitution - Missense	23:154360233-154360233,	PATHOGENIC	0.9664	26437033
FLNA	3754	COSM5730745,	breast	other	p.S1148F	Substitution - Missense	23:154360352-154360352,	PATHOGENIC	0.96263	26437033
FLNA	3754	COSM5730727,	breast	other	p.S1186W	Substitution - Missense	23:154360238-154360238,	PATHOGENIC	0.96023	26437033
FLNA	3754	COSM5730731,	breast	other	p.S1199L	Substitution - Missense	23:154360199-154360199,	PATHOGENIC	0.95878	26437033
FLNA	3754	COSM5730731,	breast	other	p.S1199L	Substitution - Missense	23:154360199-154360199,	PATHOGENIC	0.95878	26437033
FLNA	3754	COSM5730731,	breast	other	p.S1199L	Substitution - Missense	23:154360199-154360199,	PATHOGENIC	0.95878	26437033
FLNA	3754	COSM5730725,	breast	other	p.H1840L	Substitution - Missense	23:154354189-154354189,	PATHOGENIC	0.94127	26437033
FLNA	3754	COSM5730743,	breast	other	p.F264S	Substitution - Missense	23:154367474-154367474,	PATHOGENIC	0.93891	26437033
FLNA	3754	COSM50268,	breast	carcinoma	p.G2218D	Substitution - Missense	23:154352297-154352297,	PATHOGENIC	0.93314	17932254
FLNA	3754	COSM50269,	breast	carcinoma	p.G603W	Substitution - Missense	23:154364842-154364842,	PATHOGENIC	0.9157	17932254
FLNA	3754	COSM4993518,	skin	carcinoma	p.L1564L	Substitution - coding silent	23:154358264-154358264,	PATHOGENIC	0.88094	25589618
FLNA	3754	COSM5730739,	breast	other	p.K676R	Substitution - Missense	23:154364368-154364368,	PATHOGENIC	0.84185	26437033
FLNA	3754	COSM51115,	breast	carcinoma	p.G1408G	Substitution - coding silent	23:154359325-154359325,	PATHOGENIC	0.79296	17932254
FLNA	3754	COSM5730729,	breast	other	p.M424V	Substitution - Missense	23:154366183-154366183,	NEUTRAL	0.0185	26437033
FLNA	3754	COSM51116,	breast	carcinoma	p.A666A	Substitution - coding silent	23:154364550-154364550,	NEUTRAL	0.01055	17932254
FLNA	3754	COSM5731047,	breast	other	p.A1607delA, p.C1686fs*2, p.C1723delC, p.D1544delD, p.D1692fs*47, p.G783_K785delGLK, p.I1136_N1137insQL, p.P1085delP, p.T1687delT, p.T1821_K1824delTDNK	Deletion - Frameshift, Deletion - In frame, Insertion - In frame	23:154362709-154362717,	Info_not_available	Info_not_available	26437033
FLNA	3754	COSM5990059,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.V21_D22insV	Insertion - In frame	23:154371181-154371182,	Info_not_available	Info_not_available	26648538
FLNA	3754	COSM4993520,	skin	carcinoma	p.A163A	Substitution - coding silent	23:154367975-154367975,	Info_not_available	0.69345	25589618
FLNA	3754	COSM51117,	breast	carcinoma	p.K282K	Substitution - coding silent	23:154367419-154367419,	Info_not_available	0.62578	17932254
FLNA	3754	COSM1117963,	breast	carcinoma	p.V591I	Substitution - Missense	23:154364878-154364878,	Info_not_available	0.54742	22722193