Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ARAF Reconstituted Complex, coimmunoprecipitation, phage display, pull down direct interaction, physical, physical association 10967104, 11812000 0.61 BioGRID, IntAct, MINT AXL Affinity Capture-Western, Biochemical Activity, coimmunoprecipitation, far western blotting association, physical 18346204, 9178760 0.46 BioGRID, IntAct, MINT CBL Affinity Capture-MS, Affinity Capture-Western, Biochemical Activity, Far Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection, far western blotting, pull down, tandem affinity purification, two hybrid, two hybrid array, validated two hybrid association, physical, physical association 10025673, 10358153, 10620516, 10918571, 11030146, 11042121, 11087752, 11157475, 11418612, 11944898, 11994282, 14530346, 15107835, 15556646, 15581361, 16135792, 16219545, 16289966, 16982329, 17237826, 18374639, 19190244, 19380743, 19861161, 21203488, 24113870, 25814554, 7642581, 7791764, 8612729, 8621719, 8662998, 8695807, 8702998, 8896416, 8941725, 8995243, 9092538, 9160881, 9174058, 9259313, 9414268, 9461587, 9541596, 9890943, 9890970, 9918857, 9988765 0.49, 0.94 BioGRID, IntAct, MINT CD19 coimmunoprecipitation association 7684160 0.35 IntAct, MINT CD28 Affinity Capture-Western, Protein-peptide, coimmunoprecipitation, competition binding, pull down association, physical 10820259, 11526404, 19190244, 7568038, 7584133, 7807015, 8146197, 8183372, 8621607, 9417079 0.89 BioGRID, IntAct, MINT CD5 pull down, surface plasmon resonance association 9079809 0.46 IntAct, MINT CD7 Affinity Capture-Western, Reconstituted Complex, competition binding association, physical 12594831, 8918688 0.35 BioGRID, IntAct, MINT CDC42 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, experimental interaction detection, pull down association, direct interaction, physical association 25284480, 7629060, 8034624 0.79 IntAct, MINT CMIP Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical, physical association 20018188 0.52 BioGRID, IntAct, MINT CRKL Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, proximity ligation assay physical, physical association 11418612, 16135792, 16982329, 23397142, 9461587 0.59 BioGRID, IntAct, MINT CSF2RB anti bait coimmunoprecipitation, pull down association 16437163 0.46 IntAct, MINT CTLA4 coimmunoprecipitation, pull down association 7807015, 9398332, 9813138 0.64 IntAct, MINT EGFR Affinity Capture-MS, Affinity Capture-Western, Co-localization, Protein-peptide, coimmunoprecipitation, competition binding, protein array, proximity ligation assay association, direct interaction, physical, physical association 16273093, 19531499, 21701776, 25241761, 7797556, 8662998 0.78 BioGRID, IntAct, MINT ERBB2 Affinity Capture-Western, Protein-peptide, anti bait coimmunoprecipitation, protein array, pull down association, direct interaction, physical 16273093, 16843263, 21075308, 9756944 0.69 BioGRID, IntAct, MINT ERBB3 Affinity Capture-MS, Affinity Capture-Western, Protein-peptide, anti bait coimmunoprecipitation, protein array, tandem affinity purification association, direct interaction, physical, physical association 10383151, 10572067, 11546794, 11694521, 15812817, 16273093, 18803287, 20007781, 20227043, 21075308, 21278786, 22439932, 24189400, 9130710, 9756944 0.92 BioGRID, IntAct, MINT EZR Affinity Capture-Western, Reconstituted Complex, pull down association, physical 10377409 0.35 BioGRID, IntAct, MINT FGFR1 Co-localization, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, proximity ligation assay, pull down association, physical, physical association 15117958, 18412956, 25241761, 8321198 0.62 BioGRID, IntAct, MINT FLT1 Affinity Capture-Western, coimmunoprecipitation, proximity ligation assay association, physical, physical association 20805333, 23397142, 7657594 0.56 BioGRID, IntAct, MINT FLT3 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 16982329 0.40 BioGRID, IntAct, MINT GAB1 Affinity Capture-Western, Far Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, fluorescence polarization spectroscopy, pull down, two hybrid association, direct interaction, physical, physical association 10978177, 16638574, 23612964, 24728074, 8596638, 9658397, 9804835, 9891995 0.80 BioGRID, IntAct, MINT GAB2 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti tag coimmunoprecipitation, pull down association, physical, physical association 10871282, 11334882, 11782427, 14530346, 16135792, 16219545, 16253990 0.56 BioGRID, IntAct, MINT GRB10 Affinity Capture-Western, anti bait coimmunoprecipitation physical, physical association 12783867, 23246379 0.40 BioGRID, IntAct, MINT GRB2 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, mammalian protein protein interaction trap, pull down, tandem affinity purification, two hybrid pooling approach association, physical, physical association 11418612, 16219545, 18346204, 19380743, 20936779, 21706016, 25416956, 7642581, 7737969, 7759531, 9174058, 9541596, 9886492 0.86 BioGRID, IntAct, MINT HCK pull down physical association 12029088 0.40 IntAct, MINT IGF1R Co-localization, coimmunoprecipitation, proximity ligation assay, pull down, two hybrid association, physical, physical association 25241761, 7589433, 7642582, 8603569 0.75 BioGRID, IntAct, MINT INSR fluorescent resonance energy transfer, pull down association, physical association 10500481, 11796522, 9593725 0.69 IntAct, MINT IRS1 Affinity Capture-Luminescence, Affinity Capture-Western, Far Western, Protein-peptide, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, coimmunoprecipitation, cross-linking study, enzymatic study, luminescence based mammalian interactome mapping, nuclear magnetic resonance, pull down, surface plasmon resonance, two hybrid, two hybrid array, validated two hybrid association, physical, physical association 11403293, 11416002, 12107746, 12173038, 12730242, 1381348, 14511371, 14632132, 15514089, 16150444, 16230374, 16354680, 17640984, 19561084, 22974441, 23439647, 23643389, 25814554, 7680095, 7680644, 8175658, 8382612, 8628286, 9564850 0.57, 0.92 BioGRID, IntAct, MINT IRS2 Affinity Capture-MS, Affinity Capture-Western, Far Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical, physical association 12107746, 15514089, 19561084, 21241768, 23439647, 23617393, 26496610, 8910607, 9334184, 9852124 0.69 BioGRID, IntAct, MINT KIR2DL1 lex-a dimerization assay, two hybrid physical association 9751747 0.49 IntAct, MINT KIT Affinity Capture-Western, Co-localization, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, fluorescence polarization spectroscopy, proximity ligation assay association, direct interaction, physical, physical association 10022833, 11071635, 1382595, 17452978, 24728074, 25241761, 7509796, 7537096, 9233773 0.77 BioGRID, IntAct, MINT LAT Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, pull down association, physical 10811803, 11368773 0.46 BioGRID, IntAct, MINT LCK Reconstituted Complex, pull down physical, physical association 8246987, 8294442 0.40 BioGRID, IntAct, MINT LCP2 Affinity Capture-Western, Two-hybrid, pull down physical, physical association 15388330, 15929943 0.40 BioGRID, IntAct, MINT LTK Affinity Capture-Western, coimmunoprecipitation association, physical 8084603, 9223670 0.35 BioGRID, IntAct, MINT MAPK8 anti bait coimmunoprecipitation, anti tag coimmunoprecipitation association, physical association 16982329, 25284480 0.62 IntAct, MINT MED28 Affinity Capture-Western, peptide array physical, physical association 16964398 0.40 BioGRID, IntAct, MINT MYO16 anti tag coimmunoprecipitation physical association 21946561 0.40 IntAct, MINT NFKBIA Reconstituted Complex, coimmunoprecipitation, competition binding association, physical 9892650 0.46 BioGRID, IntAct, MINT NTRK1 Affinity Capture-MS, coimmunoprecipitation, competition binding association, physical 25921289, 8226808 0.46 BioGRID, IntAct, MINT PDGFRB Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, biophysical, circular dichroism, classical fluorescence spectroscopy, coimmunoprecipitation, cross-linking study, isothermal titration calorimetry, nuclear magnetic resonance, proximity ligation assay, pull down, surface plasmon resonance, two hybrid association, physical, physical association 10697503, 10752619, 11710529, 11896612, 1314164, 1330535, 15377662, 16135792, 19864249, 28514442, 7536927, 7680644, 7692233, 8382612, 8564419, 8670861, 9153411 0.95 BioGRID, IntAct, MINT PIK3CA Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, phosphotransferase assay, pull down, x-ray crystallography association, direct interaction, phosphorylation reaction, physical, physical association 11526404, 15377662, 16043515, 16135792, 19117013, 19574958, 19805105, 20018188, 20713702, 22402981, 23643389, 25253337, 26496610, 7929193 0.96 BioGRID, IntAct, MINT PIK3R1 Reconstituted Complex, coimmunoprecipitation association, physical 11337495, 8294442 0.35 BioGRID, IntAct, MINT PLCG1 pull down physical association 9020117 0.40 IntAct, MINT PTPN6 Two-hybrid, coimmunoprecipitation, pull down association, physical 10488096, 11160222 0.46 BioGRID, IntAct, MINT SEPT2 anti bait coimmunoprecipitation physical association 17024187 0.40 IntAct, MINT SHC1 Affinity Capture-MS, Affinity Capture-Western, Reconstituted Complex, coimmunoprecipitation, proximity ligation assay, pull down, tandem affinity purification association, physical, physical association 16135792, 16219545, 19380743, 19889638, 23397142, 7537361, 8621719, 8662998, 9541596 0.83 BioGRID, IntAct, MINT SRC Affinity Capture-Western, Co-localization, anti bait coimmunoprecipitation, proximity ligation assay association, physical, physical association 10487518, 19861161, 19903481, 23065768, 23397142, 24498420, 25241761 0.82 BioGRID, IntAct, MINT SSTR2 anti bait coimmunoprecipitation, pull down, surface plasmon resonance direct interaction, physical association 16917505 0.64 IntAct, MINT SYK Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, pull down, two hybrid physical, physical association 15536084, 16921024 0.58 BioGRID, IntAct, MINT TIRAP anti tag coimmunoprecipitation, fluorescence microscopy colocalization, physical association 19574958 0.46 IntAct, MINT TLR2 fluorescent resonance energy transfer physical association 23247210 0.40 IntAct, MINT TLR3 Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation physical, physical association 15502848, 16858407 0.52 BioGRID, IntAct, MINT VAV1 Affinity Capture-Western, Reconstituted Complex, pull down association, physical 17050525, 9162069, 9891995 0.35 BioGRID, IntAct, MINT VAV3 anti bait coimmunoprecipitation physical association 16982329 0.40 IntAct, MINT WASF1 anti bait coimmunoprecipitation physical association 21946561 0.40 IntAct, MINT YWHAG Affinity Capture-MS, anti bait coimmunoprecipitation, coimmunoprecipitation physical, physical association 15324660, 17353931 0.59 BioGRID, IntAct, MINT YWHAZ pull down association 10887121 0.35 IntAct, MINT