Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PIK3R1	8979	COSM6946641,	lung	carcinoma	p.D421Y	Substitution - Missense	5:68293445-68293445,	PATHOGENIC	0.99883	28481359
PIK3R1	8979	COSM6958593,	pancreas	carcinoma	p.M1V	Substitution - Missense	5:68226676-68226676,	PATHOGENIC	0.99862	28481359
PIK3R1	8979	COSM41124,	central_nervous_system	glioma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99851	18772396
PIK3R1	8979	COSM41124,	skin	malignant_melanoma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99851	28481359
PIK3R1	8979	COSM6937346,	stomach	carcinoma	p.R724*	Substitution - Nonsense	5:68297596-68297596,	PATHOGENIC	0.99849	28481359
PIK3R1	8979	COSM6935759,	large_intestine	carcinoma	p.W583*	Substitution - Nonsense	5:68295423-68295423,	PATHOGENIC	0.99831	28481359
PIK3R1	8979	COSM5760562,	central_nervous_system	glioma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99823	26919320
PIK3R1	8979	COSM5760562,	central_nervous_system	glioma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99823	28481359
PIK3R1	8979	COSM5760562,	endometrium	carcinoma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99823	28481359
PIK3R1	8979	COSM5760562,	prostate	carcinoma	p.?	Unknown	5:68295419-68295419,	PATHOGENIC	0.99823	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	18772396
PIK3R1	8979	COSM35827,	large_intestine	carcinoma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	lung	carcinoma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	18772396
PIK3R1	8979	COSM35827,	central_nervous_system	glioma	p.G376R	Substitution - Missense	5:68293310-68293310,	PATHOGENIC	0.99822	28481359
PIK3R1	8979	COSM6956942,	skin	carcinoma	p.K587I	Substitution - Missense	5:68295434-68295434,	PATHOGENIC	0.99818	28481359
PIK3R1	8979	COSM85889,	kidney	carcinoma	p.?	Unknown	5:68295418-68295418,	PATHOGENIC	0.99809	28481359
PIK3R1	8979	COSM2155617,	soft_tissue	liposarcoma	p.K379E	Substitution - Missense	5:68293319-68293319,	PATHOGENIC	0.99801	28481359
PIK3R1	8979	COSM6984406,	endometrium	carcinoma	p.V437L	Substitution - Missense	5:68293718-68293718,	PATHOGENIC	0.99791	28481359
PIK3R1	8979	COSM6978024,	skin	malignant_melanoma	p.Q432*	Substitution - Nonsense	5:68293478-68293478,	PATHOGENIC	0.9978	28481359
PIK3R1	8979	COSM6957994,	central_nervous_system	glioma	p.?	Unknown	5:68293835-68293835,	PATHOGENIC	0.99769	28481359
PIK3R1	8979	COSM6969580,	lung	carcinoma	p.H407R	Substitution - Missense	5:68293404-68293404,	PATHOGENIC	0.99764	28481359
PIK3R1	8979	COSM249900,	ovary	carcinoma	p.?	Unknown	5:68293835-68293835,	PATHOGENIC	0.99757	22214849
PIK3R1	8979	COSM3856086,	prostate	carcinoma	p.?	Unknown	5:68293835-68293835,	PATHOGENIC	0.99726	28481359
PIK3R1	8979	COSM6947171,	prostate	carcinoma	p.E596*	Substitution - Nonsense	5:68295460-68295460,	PATHOGENIC	0.9972	28481359
PIK3R1	8979	COSM6979196,	kidney	carcinoma	p.Q586*	Substitution - Nonsense	5:68295430-68295430,	PATHOGENIC	0.99719	28481359
PIK3R1	8979	COSM6979196,	kidney	carcinoma	p.Q586*	Substitution - Nonsense	5:68295430-68295430,	PATHOGENIC	0.99719	28481359
PIK3R1	8979	COSM4877550,	skin	carcinoma	p.A360V	Substitution - Missense	5:68293160-68293160,	PATHOGENIC	0.99718	28481359
PIK3R1	8979	COSM87220,	large_intestine	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	28481359
PIK3R1	8979	COSM87220,	endometrium	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	21478295
PIK3R1	8979	COSM87220,	large_intestine	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	28481359
PIK3R1	8979	COSM87220,	large_intestine	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	28481359
PIK3R1	8979	COSM87220,	large_intestine	carcinoma	p.R358*	Substitution - Nonsense	5:68293153-68293153,	PATHOGENIC	0.99714	23700467
PIK3R1	8979	COSM6920262,	breast	carcinoma	p.?	Unknown	5:68293708-68293708,	PATHOGENIC	0.99705	28481359
PIK3R1	8979	COSM6945963,	prostate	carcinoma	p.?	Unknown	5:68293707-68293707,	PATHOGENIC	0.99686	28481359
PIK3R1	8979	COSM6951607,	ovary	carcinoma	p.?	Unknown	5:68293707-68293707,	PATHOGENIC	0.99671	28481359
PIK3R1	8979	COSM6951607,	central_nervous_system	glioma	p.?	Unknown	5:68293707-68293707,	PATHOGENIC	0.99671	28481359
PIK3R1	8979	COSM5609855,	skin	malignant_melanoma	p.Q591L	Substitution - Missense	5:68295446-68295446,	PATHOGENIC	0.99644	26343386
PIK3R1	8979	COSM6935288,	endometrium	carcinoma	p.N441H	Substitution - Missense	5:68293730-68293730,	PATHOGENIC	0.99602	28481359
PIK3R1	8979	COSM6971814,	large_intestine	carcinoma	p.E218*	Substitution - Nonsense	5:68280545-68280545,	PATHOGENIC	0.99558	28481359
PIK3R1	8979	COSM5945952,	skin	malignant_melanoma	p.D352G	Substitution - Missense	5:68293136-68293136,	PATHOGENIC	0.99558	26744134
PIK3R1	8979	COSM5868746,	NS	carcinoma	p.Q475*	Substitution - Nonsense	5:68293832-68293832,	PATHOGENIC	0.99545	28481359
PIK3R1	8979	COSM6947044,	central_nervous_system	glioma	p.W597G	Substitution - Missense	5:68295463-68295463,	PATHOGENIC	0.9954	28481359
PIK3R1	8979	COSM6951785,	central_nervous_system	glioma	p.E342K	Substitution - Missense	5:68293105-68293105,	PATHOGENIC	0.99537	28481359
PIK3R1	8979	COSM5868743,	pancreas	carcinoma	p.G353R	Substitution - Missense	5:68293138-68293138,	PATHOGENIC	0.99537	27203738
PIK3R1	8979	COSM6966414,	urinary_tract	carcinoma	p.E345K	Substitution - Missense	5:68293114-68293114,	PATHOGENIC	0.99537	28481359
PIK3R1	8979	COSM6995472,	ovary	germ_cell_tumour	p.D394H	Substitution - Missense	5:68293364-68293364,	PATHOGENIC	0.99505	28954785
PIK3R1	8979	COSM6940802,	prostate	carcinoma	p.M364I	Substitution - Missense	5:68293173-68293173,	PATHOGENIC	0.99502	28481359
PIK3R1	8979	COSM94999,	breast	carcinoma	p.A634P	Substitution - Missense	5:68296256-68296256,	PATHOGENIC	0.99466	20668451
PIK3R1	8979	COSM6919239,	large_intestine	carcinoma	p.K592N	Substitution - Missense	5:68295450-68295450,	PATHOGENIC	0.99418	28481359
PIK3R1	8979	COSM6945434,	breast	carcinoma	p.E635*	Substitution - Nonsense	5:68296259-68296259,	PATHOGENIC	0.99416	28481359
PIK3R1	8979	COSM6966391,	lung	carcinoma	p.D168G	Substitution - Missense	5:68279602-68279602,	PATHOGENIC	0.99412	28481359
PIK3R1	8979	COSM87544,	urinary_tract	carcinoma	p.R574T	Substitution - Missense	5:68295300-68295300,	PATHOGENIC	0.99369	21533174
PIK3R1	8979	COSM6920205,	lung	carcinoma	p.E403K	Substitution - Missense	5:68293391-68293391,	PATHOGENIC	0.99369	28481359
PIK3R1	8979	COSM87544,	breast	carcinoma	p.R574T	Substitution - Missense	5:68295300-68295300,	PATHOGENIC	0.99369	20668451
PIK3R1	8979	COSM6932411,	large_intestine	carcinoma	p.E683*	Substitution - Nonsense	5:68297473-68297473,	PATHOGENIC	0.99345	28481359
PIK3R1	8979	COSM85930,	large_intestine	carcinoma	p.R649Q	Substitution - Missense	5:68296302-68296302,	PATHOGENIC	0.99333	19962665
PIK3R1	8979	COSM1645452,	large_intestine	carcinoma	p.F268C	Substitution - Missense	5:68280696-68280696,	PATHOGENIC	0.99331	23700467
PIK3R1	8979	COSM85927,	large_intestine	carcinoma	p.R574I	Substitution - Missense	5:68295300-68295300,	PATHOGENIC	0.99311	23680147
PIK3R1	8979	COSM39583,	central_nervous_system	glioma	p.D464H	Substitution - Missense	5:68293799-68293799,	PATHOGENIC	0.99311	18772396
PIK3R1	8979	COSM85927,	large_intestine	carcinoma	p.R574I	Substitution - Missense	5:68295300-68295300,	PATHOGENIC	0.99311	19962665
PIK3R1	8979	COSM6975787,	skin	carcinoma	p.E284K	Substitution - Missense	5:68280940-68280940,	PATHOGENIC	0.99309	28481359
PIK3R1	8979	COSM6961148,	pancreas	carcinoma	p.R481M	Substitution - Missense	5:68294552-68294552,	PATHOGENIC	0.99308	28481359
PIK3R1	8979	COSM6940118,	large_intestine	carcinoma	p.E489*	Substitution - Nonsense	5:68294575-68294575,	PATHOGENIC	0.99308	28481359
PIK3R1	8979	COSM35765,	breast	carcinoma	p.D560Y	Substitution - Missense	5:68295257-68295257,	PATHOGENIC	0.99262	28481359
PIK3R1	8979	COSM35765,	large_intestine	carcinoma	p.D560Y	Substitution - Missense	5:68295257-68295257,	PATHOGENIC	0.99262	28481359
PIK3R1	8979	COSM35765,	breast	carcinoma	p.D560Y	Substitution - Missense	5:68295257-68295257,	PATHOGENIC	0.99262	22538770
PIK3R1	8979	COSM6950110,	skin	malignant_melanoma	p.E546*	Substitution - Nonsense	5:68295215-68295215,	PATHOGENIC	0.99262	28481359
PIK3R1	8979	COSM85932,	large_intestine	carcinoma	p.E666K	Substitution - Missense	5:68297422-68297422,	PATHOGENIC	0.99257	19962665
PIK3R1	8979	COSM6912658,	lung	carcinoma	p.E469*	Substitution - Nonsense	5:68293814-68293814,	PATHOGENIC	0.99257	28481359
PIK3R1	8979	COSM6968601,	endometrium	carcinoma	p.E468*	Substitution - Nonsense	5:68293811-68293811,	PATHOGENIC	0.99257	28481359
PIK3R1	8979	COSM6937072,	cervix	carcinoma	p.D620G	Substitution - Missense	5:68296215-68296215,	PATHOGENIC	0.9918	28481359
PIK3R1	8979	COSM6915545,	large_intestine	carcinoma	p.E507*	Substitution - Nonsense	5:68294629-68294629,	PATHOGENIC	0.99135	28481359
PIK3R1	8979	COSM87229,	endometrium	carcinoma	p.E495*	Substitution - Nonsense	5:68294593-68294593,	PATHOGENIC	0.99135	21478295
PIK3R1	8979	COSM6952611,	urinary_tract	carcinoma	p.E614K	Substitution - Missense	5:68296196-68296196,	PATHOGENIC	0.99116	28481359
PIK3R1	8979	COSM6944764,	central_nervous_system	glioma	p.T473P	Substitution - Missense	5:68293826-68293826,	PATHOGENIC	0.99109	28481359
PIK3R1	8979	COSM5766196,	central_nervous_system	glioma	p.E518*	Substitution - Nonsense	5:68294662-68294662,	PATHOGENIC	0.99106	26919320
PIK3R1	8979	COSM6960758,	stomach	carcinoma	p.N488D	Substitution - Missense	5:68294572-68294572,	PATHOGENIC	0.99071	28481359
PIK3R1	8979	COSM6960758,	stomach	carcinoma	p.N488D	Substitution - Missense	5:68294572-68294572,	PATHOGENIC	0.99071	28481359
PIK3R1	8979	COSM5609852,	skin	malignant_melanoma	p.H385Y	Substitution - Missense	5:68293337-68293337,	PATHOGENIC	0.99056	26343386
PIK3R1	8979	COSM5609852,	NS	malignant_melanoma	p.H385Y	Substitution - Missense	5:68293337-68293337,	PATHOGENIC	0.99056	28481359
PIK3R1	8979	COSM1069611,	large_intestine	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	salivary_gland	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	27334835
PIK3R1	8979	COSM1069611,	endometrium	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	endometrium	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28485815
PIK3R1	8979	COSM1069611,	large_intestine	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	upper_aerodigestive_tract	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	25056374
PIK3R1	8979	COSM1069611,	endometrium	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	large_intestine	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM6954716,	lung	carcinoma	p.D569G	Substitution - Missense	5:68295285-68295285,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	large_intestine	carcinoma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM1069611,	central_nervous_system	glioma	p.K567E	Substitution - Missense	5:68295278-68295278,	PATHOGENIC	0.99051	28481359
PIK3R1	8979	COSM6913413,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q241*	Substitution - Nonsense	5:68280614-68280614,	PATHOGENIC	0.99047	28481359
PIK3R1	8979	COSM6913413,	urinary_tract	carcinoma	p.Q241*	Substitution - Nonsense	5:68280614-68280614,	PATHOGENIC	0.99047	28481359
PIK3R1	8979	COSM6919242,	large_intestine	carcinoma	p.S709Y	Substitution - Missense	5:68297552-68297552,	PATHOGENIC	0.9904	28481359
PIK3R1	8979	COSM42912,	central_nervous_system	glioma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	central_nervous_system	glioma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	salivary_gland	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	27334835
PIK3R1	8979	COSM42912,	soft_tissue	synovial_sarcoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	central_nervous_system	glioma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	central_nervous_system	glioma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	large_intestine	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	19962665
PIK3R1	8979	COSM42912,	endometrium	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28485815
PIK3R1	8979	COSM42912,	large_intestine	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	stomach	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	26489445
PIK3R1	8979	COSM42912,	lung	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	endometrium	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	21478295
PIK3R1	8979	COSM42912,	endometrium	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	large_intestine	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM42912,	large_intestine	carcinoma	p.N564D	Substitution - Missense	5:68295269-68295269,	PATHOGENIC	0.99037	28481359
PIK3R1	8979	COSM39403,	central_nervous_system	glioma	p.K459E	Substitution - Missense	5:68293784-68293784,	PATHOGENIC	0.99034	18772396
PIK3R1	8979	COSM6927471,	central_nervous_system	glioma	p.E510K	Substitution - Missense	5:68294638-68294638,	PATHOGENIC	0.99026	28481359
PIK3R1	8979	COSM6937429,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	5:68280730-68280730,	PATHOGENIC	0.98964	28481359
PIK3R1	8979	COSM6941357,	large_intestine	carcinoma	p.N527D	Substitution - Missense	5:68295158-68295158,	PATHOGENIC	0.98948	28481359
PIK3R1	8979	COSM1438323,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D560G	Substitution - Missense	5:68295258-68295258,	PATHOGENIC	0.98948	28481359
PIK3R1	8979	COSM87235,	endometrium	carcinoma	p.D548G	Substitution - Missense	5:68295222-68295222,	PATHOGENIC	0.98948	21478295
PIK3R1	8979	COSM6969915,	liver	carcinoma	p.R523K	Substitution - Missense	5:68294678-68294678,	PATHOGENIC	0.98908	28481359
PIK3R1	8979	COSM327132,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q455K	Substitution - Missense	5:68293772-68293772,	PATHOGENIC	0.98818	22675565
PIK3R1	8979	COSM6969395,	endometrium	carcinoma	p.P717S	Substitution - Missense	5:68297575-68297575,	PATHOGENIC	0.98758	28481359
PIK3R1	8979	COSM6965407,	endometrium	carcinoma	p.Q721*	Substitution - Nonsense	5:68297587-68297587,	PATHOGENIC	0.98758	28481359
PIK3R1	8979	COSM6932328,	large_intestine	carcinoma	p.H697Y	Substitution - Missense	5:68297515-68297515,	PATHOGENIC	0.9875	28481359
PIK3R1	8979	COSM6928921,	central_nervous_system	glioma	p.E601K	Substitution - Missense	5:68295475-68295475,	PATHOGENIC	0.98717	28481359
PIK3R1	8979	COSM257732,	skin	malignant_melanoma	p.R386*	Substitution - Nonsense	5:68293340-68293340,	PATHOGENIC	0.98695	28481359
PIK3R1	8979	COSM6941886,	breast	carcinoma	p.L647V	Substitution - Missense	5:68296295-68296295,	PATHOGENIC	0.98682	28481359
PIK3R1	8979	COSM5609858,	skin	malignant_melanoma	p.L570H	Substitution - Missense	5:68295288-68295288,	PATHOGENIC	0.9865	26343386
PIK3R1	8979	COSM6911220,	endometrium	carcinoma	p.Y580N	Substitution - Missense	5:68295317-68295317,	PATHOGENIC	0.9865	28481359
PIK3R1	8979	COSM5766197,	central_nervous_system	glioma	p.L449*	Substitution - Nonsense	5:68293755-68293755,	PATHOGENIC	0.98643	26919320
PIK3R1	8979	COSM6913486,	skin	carcinoma	p.Q478*	Substitution - Nonsense	5:68294542-68294542,	PATHOGENIC	0.986	28481359
PIK3R1	8979	COSM85933,	large_intestine	carcinoma	p.A682V	Substitution - Missense	5:68297471-68297471,	PATHOGENIC	0.98589	19962665
PIK3R1	8979	COSM6951151,	cervix	carcinoma	p.S690F	Substitution - Missense	5:68297495-68297495,	PATHOGENIC	0.98589	28481359
PIK3R1	8979	COSM6957358,	penis	carcinoma	p.R590W	Substitution - Missense	5:68295442-68295442,	PATHOGENIC	0.98557	28481359
PIK3R1	8979	COSM40940,	endometrium	carcinoma	p.L570P	Substitution - Missense	5:68295288-68295288,	PATHOGENIC	0.98459	28481359
PIK3R1	8979	COSM40940,	central_nervous_system	glioma	p.L570P	Substitution - Missense	5:68295288-68295288,	PATHOGENIC	0.98459	28481359
PIK3R1	8979	COSM40940,	central_nervous_system	glioma	p.L570P	Substitution - Missense	5:68295288-68295288,	PATHOGENIC	0.98459	18772396
PIK3R1	8979	COSM1069619,	endometrium	carcinoma	p.L573P	Substitution - Missense	5:68295297-68295297,	PATHOGENIC	0.98459	28485815
PIK3R1	8979	COSM1069619,	large_intestine	carcinoma	p.L573P	Substitution - Missense	5:68295297-68295297,	PATHOGENIC	0.98459	28481359
PIK3R1	8979	COSM6980078,	large_intestine	carcinoma	p.A331V	Substitution - Missense	5:68292334-68292334,	PATHOGENIC	0.98451	28481359
PIK3R1	8979	COSM6957987,	endometrium	carcinoma	p.L584F	Substitution - Missense	5:68295426-68295426,	PATHOGENIC	0.98444	28481359
PIK3R1	8979	COSM6952187,	large_intestine	carcinoma	p.D615Y	Substitution - Missense	5:68296199-68296199,	PATHOGENIC	0.98404	28481359
PIK3R1	8979	COSM87232,	endometrium	carcinoma	p.Y334*	Substitution - Nonsense	5:68292344-68292344,	PATHOGENIC	0.98389	21478295
PIK3R1	8979	COSM85936,	breast	carcinoma	p.L449S	Substitution - Missense	5:68293755-68293755,	PATHOGENIC	0.98363	19962665
PIK3R1	8979	COSM6971168,	lung	carcinoma	p.W333R	Substitution - Missense	5:68292339-68292339,	PATHOGENIC	0.98324	28481359
PIK3R1	8979	COSM1645453,	large_intestine	carcinoma	p.F268L	Substitution - Missense	5:68280697-68280697,	PATHOGENIC	0.9797	23700467
PIK3R1	8979	COSM1717421,	breast	carcinoma	p.R642L	Substitution - Missense	5:68296281-68296281,	PATHOGENIC	0.97875	24229379
PIK3R1	8979	COSM6930170,	urinary_tract	carcinoma	p.E140K	Substitution - Missense	5:68273473-68273473,	PATHOGENIC	0.97578	28481359
PIK3R1	8979	COSM6930170,	lung	carcinoma	p.E140K	Substitution - Missense	5:68273473-68273473,	PATHOGENIC	0.97578	28481359
PIK3R1	8979	COSM5945951,	skin	malignant_melanoma	p.E137G	Substitution - Missense	5:68273465-68273465,	PATHOGENIC	0.97521	26744134
PIK3R1	8979	COSM6935287,	endometrium	carcinoma	p.S229L	Substitution - Missense	5:68280579-68280579,	PATHOGENIC	0.97187	28481359
PIK3R1	8979	COSM6955995,	breast	carcinoma	p.R562P	Substitution - Missense	5:68295264-68295264,	PATHOGENIC	0.97111	28481359
PIK3R1	8979	COSM1581456,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A210D	Substitution - Missense	5:68279728-68279728,	PATHOGENIC	0.96987	23292937
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	19962665
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	28481359
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	19962665
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	28481359
PIK3R1	8979	COSM85926,	skin	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	25589618
PIK3R1	8979	COSM85926,	large_intestine	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	23680147
PIK3R1	8979	COSM85926,	endometrium	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	21478295
PIK3R1	8979	COSM85926,	endometrium	carcinoma	p.R348*	Substitution - Nonsense	5:68293123-68293123,	PATHOGENIC	0.9674	21478295
PIK3R1	8979	COSM85937,	large_intestine	carcinoma	p.R543I	Substitution - Missense	5:68295207-68295207,	PATHOGENIC	0.96364	19962665
PIK3R1	8979	COSM4413604,	endometrium	carcinoma	p.Y698*	Substitution - Nonsense	5:68297520-68297520,	PATHOGENIC	0.96096	25308272
PIK3R1	8979	COSM6971613,	skin	carcinoma	p.Y203C	Substitution - Missense	5:68279707-68279707,	PATHOGENIC	0.95924	28481359
PIK3R1	8979	COSM6909497,	urinary_tract	carcinoma	p.A277P	Substitution - Missense	5:68280722-68280722,	PATHOGENIC	0.95676	28481359
PIK3R1	8979	COSM6904275,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R523S	Substitution - Missense	5:68295148-68295148,	PATHOGENIC	0.95103	27248180
PIK3R1	8979	COSM6930387,	lung	carcinoma	p.D126Y	Substitution - Missense	5:68273431-68273431,	PATHOGENIC	0.94932	28481359
PIK3R1	8979	COSM6974678,	large_intestine	carcinoma	p.F247L	Substitution - Missense	5:68280634-68280634,	PATHOGENIC	0.9493	28481359
PIK3R1	8979	COSM6975487,	large_intestine	carcinoma	p.L449I	Substitution - Missense	5:68293754-68293754,	PATHOGENIC	0.94803	28481359
PIK3R1	8979	COSM6946640,	lung	carcinoma	p.R262G	Substitution - Missense	5:68280677-68280677,	PATHOGENIC	0.94489	28481359
PIK3R1	8979	COSM3727824,	upper_aerodigestive_tract	carcinoma	p.M326I	Substitution - Missense	5:68292320-68292320,	PATHOGENIC	0.94368	24667986
PIK3R1	8979	COSM3727824,	breast	carcinoma	p.M326I	Substitution - Missense	5:68292320-68292320,	PATHOGENIC	0.94368	28270497
PIK3R1	8979	COSM3071985,	prostate	carcinoma	p.R639*	Substitution - Nonsense	5:68296271-68296271,	PATHOGENIC	0.94286	20579941
PIK3R1	8979	COSM3071985,	prostate	carcinoma	p.R639*	Substitution - Nonsense	5:68296271-68296271,	PATHOGENIC	0.94286	20579941
PIK3R1	8979	COSM3071985,	prostate	carcinoma	p.R639*	Substitution - Nonsense	5:68296271-68296271,	PATHOGENIC	0.94286	20579941
PIK3R1	8979	COSM3071985,	large_intestine	carcinoma	p.R639*	Substitution - Nonsense	5:68296271-68296271,	PATHOGENIC	0.94286	28481359
PIK3R1	8979	COSM3975610,	breast	carcinoma	p.A185T	Substitution - Missense	5:68279652-68279652,	PATHOGENIC	0.93885	28270497
PIK3R1	8979	COSM3617617,	central_nervous_system	glioma	p.Y463*	Substitution - Nonsense	5:68293798-68293798,	PATHOGENIC	0.93637	28481359
PIK3R1	8979	COSM87233,	endometrium	carcinoma	p.R301*	Substitution - Nonsense	5:68280991-68280991,	PATHOGENIC	0.9352	21478295
PIK3R1	8979	COSM6980330,	kidney	carcinoma	p.T148I	Substitution - Missense	5:68273954-68273954,	PATHOGENIC	0.93007	28481359
PIK3R1	8979	COSM6966307,	breast	carcinoma	p.R465*	Substitution - Nonsense	5:68293802-68293802,	PATHOGENIC	0.92919	28481359
PIK3R1	8979	COSM6912989,	lung	carcinoma	p.Q214L	Substitution - Missense	5:68280534-68280534,	PATHOGENIC	0.92742	28481359
PIK3R1	8979	COSM5836057,	central_nervous_system	glioma	p.P116T	Substitution - Missense	5:68273401-68273401,	PATHOGENIC	0.92466	26919320
PIK3R1	8979	COSM3429594,	large_intestine	carcinoma	p.S208Y	Substitution - Missense	5:68279722-68279722,	PATHOGENIC	0.92236	28481359
PIK3R1	8979	COSM3429594,	endometrium	carcinoma	p.S208Y	Substitution - Missense	5:68279722-68279722,	PATHOGENIC	0.92236	28481359
PIK3R1	8979	COSM6949112,	skin	carcinoma	p.S254F	Substitution - Missense	5:68280654-68280654,	PATHOGENIC	0.91712	28481359
PIK3R1	8979	COSM6968479,	central_nervous_system	glioma	p.T283I	Substitution - Missense	5:68280938-68280938,	PATHOGENIC	0.91494	28481359
PIK3R1	8979	COSM5356390,	endometrium	carcinoma	p.R503W	Substitution - Missense	5:68294617-68294617,	PATHOGENIC	0.9145	28481359
PIK3R1	8979	COSM85931,	large_intestine	carcinoma	p.R642*	Substitution - Nonsense	5:68296280-68296280,	PATHOGENIC	0.91404	19962665
PIK3R1	8979	COSM85931,	skin	carcinoma	p.R642*	Substitution - Nonsense	5:68296280-68296280,	PATHOGENIC	0.91404	28481359
PIK3R1	8979	COSM5609861,	skin	malignant_melanoma	p.S147L	Substitution - Missense	5:68273951-68273951,	PATHOGENIC	0.90457	26343386
PIK3R1	8979	COSM85928,	large_intestine	carcinoma	p.N527K	Substitution - Missense	5:68295160-68295160,	PATHOGENIC	0.90016	19962665
PIK3R1	8979	COSM6921639,	prostate	carcinoma	p.N157H	Substitution - Missense	5:68273980-68273980,	PATHOGENIC	0.89157	28481359
PIK3R1	8979	COSM6965694,	endometrium	carcinoma	p.F646L	Substitution - Missense	5:68296294-68296294,	PATHOGENIC	0.88975	28481359
PIK3R1	8979	COSM1695845,	central_nervous_system	glioma	p.R557*	Substitution - Nonsense	5:68295248-68295248,	PATHOGENIC	0.88855	28481359
PIK3R1	8979	COSM1695845,	skin	malignant_melanoma	p.R557*	Substitution - Nonsense	5:68295248-68295248,	PATHOGENIC	0.88855	26343386
PIK3R1	8979	COSM1695845,	large_intestine	carcinoma	p.R557*	Substitution - Nonsense	5:68295248-68295248,	PATHOGENIC	0.88855	28481359
PIK3R1	8979	COSM6932327,	large_intestine	carcinoma	p.A183T	Substitution - Missense	5:68279646-68279646,	PATHOGENIC	0.88778	28481359
PIK3R1	8979	COSM6937716,	urinary_tract	carcinoma	p.E120D	Substitution - Missense	5:68273415-68273415,	PATHOGENIC	0.88043	28481359
PIK3R1	8979	COSM87226,	endometrium	carcinoma	p.C498*	Substitution - Nonsense	5:68294604-68294604,	PATHOGENIC	0.87361	21478295
PIK3R1	8979	COSM6982684,	endometrium	carcinoma	p.L616V	Substitution - Missense	5:68296202-68296202,	PATHOGENIC	0.87005	28481359
PIK3R1	8979	COSM87241,	endometrium	carcinoma	p.D434_Q475del	Deletion - In frame	5:68293836-68293836,	PATHOGENIC	0.86427	21478295
PIK3R1	8979	COSM87241,	skin	malignant_melanoma	p.D434_Q475del	Deletion - In frame	5:68293836-68293836,	PATHOGENIC	0.86427	28481359
PIK3R1	8979	COSM6980936,	lung	carcinoma	p.L209F	Substitution - Missense	5:68279726-68279726,	PATHOGENIC	0.86402	28481359
PIK3R1	8979	COSM6980936,	lung	carcinoma	p.L209F	Substitution - Missense	5:68279726-68279726,	PATHOGENIC	0.86402	28481359
PIK3R1	8979	COSM6986093,	breast	carcinoma	p.I133M	Substitution - Missense	5:68273454-68273454,	PATHOGENIC	0.8511	28481359
PIK3R1	8979	COSM327131,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T454I	Substitution - Missense	5:68293770-68293770,	PATHOGENIC	0.84329	22675565
PIK3R1	8979	COSM5019326,	soft_tissue	haemangioblastoma	p.I207I	Substitution - coding silent	5:68279720-68279720,	PATHOGENIC	0.82709	25589003
PIK3R1	8979	COSM5019326,	soft_tissue	haemangioblastoma	p.I207I	Substitution - coding silent	5:68279720-68279720,	PATHOGENIC	0.82709	25589003
PIK3R1	8979	COSM85934,	large_intestine	carcinoma	p.R162*	Substitution - Nonsense	5:68273995-68273995,	PATHOGENIC	0.79909	19962665
PIK3R1	8979	COSM87237,	endometrium	carcinoma	p.Q475_E476>IMLQ	Complex - insertion inframe	5:68294523-68294523,	PATHOGENIC	0.7737	21478295
PIK3R1	8979	COSM43181,	large_intestine	carcinoma	p.R461*	Substitution - Nonsense	5:68293790-68293790,	PATHOGENIC	0.72335	28481359
PIK3R1	8979	COSM5609849,	skin	malignant_melanoma	p.R649R	Substitution - coding silent	5:68296303-68296303,	NEUTRAL	0.47115	26343386
PIK3R1	8979	COSM6444825,	endometrium	carcinoma	p.I220T	Substitution - Missense	5:68280552-68280552,	NEUTRAL	0.44253	27159395
PIK3R1	8979	COSM6444825,	endometrium	carcinoma	p.I220T	Substitution - Missense	5:68280552-68280552,	NEUTRAL	0.44253	27159395
PIK3R1	8979	COSM87242,	endometrium	carcinoma	p.?	Unknown	5:68294515-68294515,	NEUTRAL	0.20149	21478295
PIK3R1	8979	COSM85925,	large_intestine	carcinoma	p.N285H	Substitution - Missense	5:68280943-68280943,	NEUTRAL	0.19591	19962665
PIK3R1	8979	COSM6933741,	lung	carcinoma	p.T169A	Substitution - Missense	5:68279604-68279604,	NEUTRAL	0.03541	28481359
PIK3R1	8979	COSM4604513,	upper_aerodigestive_tract	carcinoma	p.T576T	Substitution - coding silent	5:68295307-68295307,	NEUTRAL	0.03347	25056374
PIK3R1	8979	COSM87243,	endometrium	carcinoma	p.?	Unknown	5:68293278-68293278,	NEUTRAL	0.03288	21478295
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	breast	carcinoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	28270497
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM4407349,	soft_tissue	haemangioblastoma	p.Y73Y	Substitution - coding silent	5:68226894-68226894,	NEUTRAL	0.02949	25589003
PIK3R1	8979	COSM6849505,	ovary	carcinoma	p.S295*, p.V445E	Substitution - Missense, Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	28125452
PIK3R1	8979	COSM5991643,	breast	carcinoma	p.Y580fs*19	Frameshift	Info_not_available	Info_not_available	Info_not_available	25927147
PIK3R1	8979	COSM6024551,	NS	carcinoma	p.G599fs*63, p.K448fs*32, p.N564D	Frameshift, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26182302
PIK3R1	8979	COSM5977617,	central_nervous_system	glioma	p.?	Unknown	5:68295324-68295325,	Info_not_available	Info_not_available	26487540
PIK3R1	8979	COSM5352304,	endometrium	carcinoma	p.?fs*?, p.A277T, p.L637M	Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	26492180
PIK3R1	8979	COSM132926,	breast	hyperplasia	p.K567E	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26718977
PIK3R1	8979	COSM5878513,	central_nervous_system	glioma	p.?, p.?_?del	Deletion - In frame, Unknown	Info_not_available	Info_not_available	Info_not_available	26919320
PIK3R1	8979	COSM5881435,	endometrium	carcinoma	p.?fs*?, p.Q579Y	Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	27170661
PIK3R1	8979	COSM6865942,	breast	carcinoma	p.E451_Y452>G, p.I571_Q572del, p.S460fs*5	Complex - deletion inframe, Deletion - In frame, Insertion - Frameshift	5:68295290-68295295,	Info_not_available	Info_not_available	27284958
PIK3R1	8979	COSM5967130,	salivary_gland	carcinoma	p.?	Unknown	5:68295325-68295326,	Info_not_available	Info_not_available	27334835
PIK3R1	8979	COSM5967250,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M582T	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27449473
PIK3R1	8979	COSM6023859,	upper_aerodigestive_tract	carcinoma	p.?, p.D569_L570insPD	Insertion - In frame, Unknown	5:68295287-68295288,	Info_not_available	Info_not_available	25850957
PIK3R1	8979	COSM318378,	breast	carcinoma	p.E462_R465delEYDR	Deletion - In frame	5:68293791-68293802,	Info_not_available	Info_not_available	28270497
PIK3R1	8979	COSM43200,	kidney	Wilms_tumour	p.R557_K561>Q	Complex - deletion inframe	5:68295249-68295260,	Info_not_available	Info_not_available	28326956
PIK3R1	8979	COSM6842056,	large_intestine	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	28465371
PIK3R1	8979	COSM6904348,	endometrium	carcinoma	p.A444_L449del, p.L380fs*16, p.N453_Q455del	Deletion - Frameshift, Deletion - In frame	5:68293766-68293774,	Info_not_available	Info_not_available	28485815
PIK3R1	8979	COSM6444623,	breast	other	p.L347del	Deletion - In frame	5:68293121-68293123,	Info_not_available	Info_not_available	28513873
PIK3R1	8979	COSM6908609,	upper_aerodigestive_tract	carcinoma	p.L637fs*25	Deletion - Frameshift	5:68296265-68296265,	Info_not_available	Info_not_available	28581676
PIK3R1	8979	COSM5752295,	breast	carcinoma	p.?	Unknown	5:68295317-68295326,	Info_not_available	Info_not_available	28685160
PIK3R1	8979	COSM5945733,	breast	carcinoma	p.E451_Y452del	Deletion - In frame	Info_not_available	Info_not_available	Info_not_available	28921573
PIK3R1	8979	COSM6906745,	breast, endometrium, large_intestine	carcinoma	p.L449_H450>Y, p.P568_T576delPDLIQLRKT, p.S460delS, p.V436fs*8	Complex - deletion inframe, Deletion - Frameshift, Deletion - In frame	5:68295282-68295308,	Info_not_available	Info_not_available	29420467
PIK3R1	8979	COSM54575,	breast, central_nervous_system	carcinoma, glioma	p.453_454insN, p.L380del	Deletion - In frame, Insertion - In frame	5:68293767-68293768,	Info_not_available	Info_not_available	Info_not_available
PIK3R1	8979	COSM249901,	ovary	carcinoma	p.?, p.E403_I405>D, p.N564fs*?	Complex - deletion inframe, Unknown	5:68294534-68294535,	Info_not_available	Info_not_available	22214849
PIK3R1	8979	COSM85888,	large_intestine, ovary	carcinoma	p.?, p.L570_D578del, p.L570_Q572del, p.M582_D605>I	Complex - deletion inframe, Deletion - In frame, Unknown	5:68295488-68295491,	Info_not_available	Info_not_available	11606375
PIK3R1	8979	COSM85939,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N636fs*26	Deletion - Frameshift	5:68296263-68296263,	Info_not_available	Info_not_available	11986952
PIK3R1	8979	COSM85883,	central_nervous_system	glioma	p.Y580fs*1	Deletion - Frameshift	5:68295319-68295599,	Info_not_available	Info_not_available	15605984
PIK3R1	8979	COSM33546,	breast	carcinoma	p.N453_T454insN	Insertion - In frame	5:68293767-68293768,	Info_not_available	Info_not_available	16959974
PIK3R1	8979	COSM43347,	skin	carcinoma	p.Q579fs*23	Insertion - Frameshift	5:68295314-68295315,	Info_not_available	Info_not_available	19634059
PIK3R1	8979	COSM85938,	large_intestine, pancreas	carcinoma	p.I381fs*15, p.K668_H669insLK	Deletion - Frameshift, Insertion - In frame	5:68297431-68297432,	Info_not_available	Info_not_available	19962665
PIK3R1	8979	COSM87240,	endometrium	carcinoma	p.?, p.D434_Q475del, p.D464fs*2, p.E451_Y452del, p.F456_R461>S, p.F456_R461del, p.H450_E451del, p.K459del, p.K511fs*2, p.Q457_R461del, p.Q475_E476>VLQ, p.R542del, p.R574_T576del, p.R577_M582>K, p.S460fs*5, p.S702fs*26, p.T454_D464del, p.Y463_L466del, p.Y463fs*1	Complex - deletion inframe, Complex - insertion inframe, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Unknown	5:68297529-68297530,	Info_not_available	Info_not_available	21478295
PIK3R1	8979	COSM132929,	endometrium	carcinoma	p.G376R, p.K567E, p.L570P, p.N260S, p.R386G, p.R557_D560del, p.R639*, p.S460fs*?, p.T473S, p.Y467_E468insGEYDRLYE	Deletion - In frame, Frameshift, Insertion - In frame, Substitution - Missense, Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	21984976
PIK3R1	8979	COSM5025133,	breast	carcinoma	p.L380fs*16	Deletion - Frameshift	5:68293320-68293323,	Info_not_available	Info_not_available	25850943
PIK3R1	8979	COSM1155748,	skin	malignant_melanoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	22912864
PIK3R1	8979	COSM1716345,	endometrium	carcinoma	p.A331V, p.H180fs*?, p.K567E, p.L570P, p.N260S, p.Q586fs*?, p.R386G, p.R557_K561>Q, p.S460fs*?, p.Y467_E468insGEYDRLYE	Complex - deletion inframe, Frameshift, Insertion - In frame, Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	23674493
PIK3R1	8979	COSM3736943,	skin	malignant_melanoma	p.D464_E468>E	Complex - deletion inframe	5:68293801-68293812,	Info_not_available	Info_not_available	23851445
PIK3R1	8979	COSM3734746,	urinary_tract	carcinoma	p.I290fs*4	Frameshift	Info_not_available	Info_not_available	Info_not_available	24192927
PIK3R1	8979	COSM35737,	breast	carcinoma	p.E451_F456del, p.K575_R577del, p.L449del, p.M563_N564ins13, p.P568_T576del, p.R574_K575insMR, p.T576del, p.Y580_L581del	Deletion - In frame, Insertion - In frame	5:68295317-68295322,	Info_not_available	Info_not_available	24229379
PIK3R1	8979	COSM5415272,	endometrium	carcinoma	p.?fs*?, p.L570_I571insI, p.T576delT	Deletion - In frame, Insertion - In frame, Unknown	5:68295304-68295306,	Info_not_available	Info_not_available	25233892
PIK3R1	8979	COSM5945733,	central_nervous_system	glioma	p.E451_Y452del	Deletion - In frame	Info_not_available	Info_not_available	Info_not_available	25257301
PIK3R1	8979	COSM4766159,	central_nervous_system	glioma	p.E462fs*?, p.K567E	Frameshift, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25529192
PIK3R1	8979	COSM5574323,	skin	malignant_melanoma	p.R348*	Substitution - Nonsense	Info_not_available	Info_not_available	Info_not_available	25705882
PIK3R1	8979	COSM5033551,	central_nervous_system	glioma	p.?, p.E468del, p.E469_Y470ins12, p.I405del, p.K567E, p.L449del, p.R557_I559del, p.S412Y, p.S429Y	Deletion - In frame, Insertion - In frame, Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25740784
PIK3R1	8979	COSM40466,	central_nervous_system	glioma	p.H450_E451del, p.I571I	Deletion - In frame, Substitution - coding silent	5:68295292-68295292,	Info_not_available	0.58101, Info_not_available	18772396
PIK3R1	8979	COSM87228,	autonomic_ganglia, breast, central_nervous_system, cervix, endometrium, kidney, large_intestine, lung, ovary, prostate, salivary_gland, soft_tissue, stomach, thyroid, upper_aerodigestive_tract, urinary_tract	angiosarcoma, carcinoma, glioma, liposarcoma, neuroblastoma, other, solitary_fibrous_tumour	p.?, p.A486fs*6, p.D440_E451del12, p.D440_K448delDNIEAVGKK, p.D440delD, p.D464_R465ins12, p.D569_L581>E, p.D569fs*34, p.D578P, p.D578_M582>E, p.D578fs*23, p.D605fs*58, p.D708fs*8, p.E120_A123delEQFA, p.E403_L404>V, p.E451_Y452delEY, p.E451_Y452insHE, p.E458_K459delEK, p.E458delE, p.E462_R465delEYDR, p.E462_Y463>D, p.E462fs*2, p.E468_E469insDRLYE, p.E468_E469insGEYDRLYE, p.E468_E469insYDRLYE, p.E558_R562delEIDKR, p.E596fs*3, p.E650fs*8, p.F456_K459delFQEK, p.F456_Q457delFQ, p.F646_S652>LL, p.G100fs*15, p.G35fs*4, p.G446_L449>V, p.G588fs*7, p.G665fs*3, p.G678fs*9, p.H385fs*11, p.H450_E451delHE, p.H450_K459del10, p.H706fs*>20, p.I405_L420del16, p.I405delI, p.I442_N453del12, p.I442fs*30, p.I566_P568>T, p.I571_K575delIQLRK, p.I571_L581del11, p.I571_R574delIQLR, p.I571fs*31, p.I82fs*32, p.K447fs*31, p.K448_N453delKLHEYN, p.K448_Y452delKLHEY, p.K459del, p.K561fs*7, p.K567_I571delKPDLI, p.K567_L570delKPDL, p.K567delK, p.K575_L581>M, p.K575_R577delKTR, p.L356fs*17, p.L380delL, p.L380fs*1, p.L396fs*6, p.L449_H450insQ, p.L449_Y452>FH, p.L449delL, p.L449fs*3, p.L573_K575delLRK, p.L594V, p.L710fs*5, p.M326fs*6, p.M563fs*5, p.N282fs*3, p.N378delN, p.N441_T454del14, p.N453_Q455>K, p.N453_Q457delNTQFQ, p.N453_S460>K, p.N453delN, p.P568_L573delPDLIQL, p.P568fs*34, p.Q455_F456insHEYNTQ, p.Q572fs*33, p.R461_E462>Q, p.R465_L466insR, p.R557fs*6, p.R557fs*7, p.R574delR, p.R577_D578insKTR, p.R577_L581>SI, p.R577delR, p.R577fs*19, p.S155fs*23, p.S460_R461insQFQEKS, p.S460fs*20, p.S709_L710delSL, p.T576delT, p.T623fs*40, p.V401_H407delVVELINH, p.V402_L413del12, p.V661fs*3, p.V663fs*1, p.V671fs*15, p.Y334fs*6, p.Y390fs*6, p.Y452_N453insF, p.Y452_N453insY, p.Y452_Q457delYNTQFQ, p.Y463_D464insEKSREY, p.Y463_L466del, p.Y470_T471insDRLYEEY, p.Y580_L581>M	Complex - deletion inframe, Complex - frameshift, Deletion - Frameshift, Deletion - In frame, Insertion - Frameshift, Insertion - In frame, Substitution - Missense, Unknown	5:68297552-68297552,	Info_not_available	0.51672, Info_not_available	28481359