Interacting Partner	Detection_method	PPI_type	Lit_support	PPI_score	Source_databases
AGAP2	anti tag coimmunoprecipitation, pull down	physical association	21720388	0.52	IntAct, MINT
ARF6 	anti bait coimmunoprecipitation	association	17167487	0.35	IntAct
ARRB2	Affinity Capture-Western, anti bait coimmunoprecipitation	direct interaction, physical, physical association	19122674	0.54	BioGRID, IntAct
ATIC	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical	25687571	0.35	BioGRID, IntAct
CRK	two hybrid	physical association	15522217	0.37	IntAct
CRKL	two hybrid	physical association	15522217	0.37	IntAct
CYTH2 	anti bait coimmunoprecipitation	association	17167487	0.35	IntAct
CYTH3 	anti bait coimmunoprecipitation	association	17167487	0.35	IntAct
DCN	enzyme linked immunosorbent assay	direct interaction	24389353	0.44	IntAct
EBI-4399559	anti tag coimmunoprecipitation	physical association	23354051	0.40	IntAct
ENPP1	Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, enzyme linked immunosorbent assay	physical, physical association	10615944, 11289049	0.52	BioGRID, IntAct
GRB10	Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, protein three hybrid, pull down, two hybrid	direct interaction, physical, physical association	10871840, 15664450, 19648926, 7479769, 8621530, 9006901, 9506989	0.40, 0.58	BioGRID, IntAct, MINT
GRB14	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, bioluminescence resonance energy transfer	physical, physical association	11726652, 16582879, 19648926, 24535599	0.40	BioGRID, IntAct, MINT
HACD3 	anti bait coimmunoprecipitation	association	25687571	0.35	IntAct
IGF1	competition binding, x-ray crystallography	direct interaction, physical association	26027733, 8452530	0.40, 0.44	IntAct
INS	x-ray crystallography	direct interaction	23302862	0.44	IntAct
INSR	Biochemical Activity, Reconstituted Complex, molecular sieving, protein kinase assay, x-ray crystallography	direct interaction, phosphorylation reaction, physical	16957736, 18278056, 2033070, 23302862, 26853939	0.44, 0.73	BioGRID, IntAct
IRF7	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
IRS1	Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, two hybrid	association, direct interaction, physical, physical association	11606564, 11781100, 16582879, 17167487, 25667086, 7499194, 7935368, 8626379, 8662806	0.35, 0.70	BioGRID, IntAct, MINT
IRS2	Two-hybrid, pull down, two hybrid	direct interaction, physical, physical association	8626379, 8662806	0.53	BioGRID, IntAct, MINT
KIF5A	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical	25687571	0.35	BioGRID, IntAct
KRT31	Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid	physical, physical association	25416956	0.56	BioGRID, IntAct
MAD2L1	imaging technique, two hybrid, two hybrid array, two hybrid prey pooling approach	physical association	9092546, 	0.46, 0.49	IntAct, MINT
PIK3R1	fluorescent resonance energy transfer, pull down	association, physical association	10500481, 11796522, 9593725	0.69	IntAct, MINT
PLCG1	Protein-peptide, coimmunoprecipitation, cross-linking study, fluorescence microscopy, pull down	colocalization, direct interaction, physical, physical association	11796522, 14568990, 22974441, 9593725	0.80	BioGRID, IntAct, MINT
PRKAA2	Affinity Capture-Western, anti bait coimmunoprecipitation	association, physical	25687571	0.35	BioGRID, IntAct
PTPN1	Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, bimolecular fluorescence complementation, bioluminescence resonance energy transfer, coimmunoprecipitation, filter binding, fluorescent resonance energy transfer, genetic interference, phosphatase assay, protein kinase assay, pull down, x-ray crystallography	association, colocalization, dephosphorylation reaction, direct interaction, phosphorylation reaction, physical, physical association	11163213, 11506178, 11579209, 11726652, 12237455, 12634852, 14722096, 15588987, 16271887, 16582879, 16926280, 17092689, 17159996, 17481567, 19029027, 21806020, 8702689, 8999839	0.44, 0.98	BioGRID, IntAct, MINT
PTPN11	Affinity Capture-Western, Reconstituted Complex, pull down	association, physical, physical association	7493946, 8135823, 9593725	0.56	BioGRID, IntAct, MINT
PTPN12	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPN2	anti bait coimmunoprecipitation	physical association	15192089	0.40	IntAct, MINT
PTPN3	phosphatase assay	dephosphorylation reaction	25728925	0.44	IntAct
PTPRB	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRC 	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRG	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRJ	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
PTPRK	Affinity Capture-MS, phosphatase assay	dephosphorylation reaction, physical	19167335, 26186194, 28514442	0.44	BioGRID, IntAct
PTPRO	phosphatase assay	dephosphorylation reaction	19167335	0.44	IntAct
RASA1	Affinity Capture-Western, pull down	physical, physical association	1331107, 9593725	0.40	BioGRID, IntAct, MINT
RHOB	fluorescence microscopy	colocalization	14722096	0.27	IntAct, MINT
SH2B1	Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, two hybrid	association, physical, physical association	10594240, 15767667, 9742218	0.48	BioGRID, IntAct, MINT
SHC1	Reconstituted Complex, Two-hybrid, pull down, two hybrid	physical, physical association	10803466, 15629149, 7499194, 9593725	0.57	BioGRID, IntAct, MINT
SORBS1 	anti bait coimmunoprecipitation	physical association	11374898	0.40	IntAct
STAT5B	Affinity Capture-Western, two hybrid	physical, physical association	12456798, 9428692	0.37	BioGRID, IntAct, MINT
TEAD1	Two-hybrid, two hybrid array	physical, physical association	21988832	0.37	BioGRID, IntAct
TMEM17	Proximity Label-MS, proximity-dependent biotin identification	association, physical	26638075	0.35	BioGRID, IntAct
YWHAB	two hybrid	physical association	15629149	0.37	IntAct