Interacting Partner Detection_method PPI_type Lit_support PPI_score Source_databases ACTB anti bait coimmunoprecipitation association 25687571 0.35 IntAct AGAP2 anti tag coimmunoprecipitation, pull down physical association 21720388 0.52 IntAct, MINT AHSG Reconstituted Complex physical 7906861 NA BioGRID ARF6 anti bait coimmunoprecipitation association 17167487 0.35 IntAct ARRB2 Affinity Capture-Western, anti bait coimmunoprecipitation direct interaction, physical, physical association 19122674 0.54 BioGRID, IntAct ATIC Affinity Capture-Western, anti bait coimmunoprecipitation association, physical 25687571 0.35 BioGRID, IntAct CAV1 Affinity Capture-Western physical 10598578 NA BioGRID CLEC3A Affinity Capture-MS physical 28514442 NA BioGRID CRK two hybrid physical association 15522217 0.37 IntAct CRKL two hybrid physical association 15522217 0.37 IntAct CSK Two-hybrid physical 10026153 NA BioGRID CYTH2 anti bait coimmunoprecipitation association 17167487 0.35 IntAct CYTH3 anti bait coimmunoprecipitation association 17167487 0.35 IntAct DCN enzyme linked immunosorbent assay direct interaction 24389353 0.44 IntAct DNASE1L2 Affinity Capture-MS physical 28514442 NA BioGRID DOK1 Biochemical Activity physical 11551902 NA BioGRID DUSP18 Affinity Capture-Western, Two-hybrid physical 28065597 NA BioGRID DUSP19 Two-hybrid physical 28065597 NA BioGRID EBI-4399559 anti tag coimmunoprecipitation physical association 23354051 0.40 IntAct ENPP1 Affinity Capture-Western, Reconstituted Complex, anti bait coimmunoprecipitation, enzyme linked immunosorbent assay physical, physical association 10615944, 11289049 0.52 BioGRID, IntAct FAM19A3 Affinity Capture-MS physical 28514442 NA BioGRID FAM19A4 Affinity Capture-MS physical 28514442 NA BioGRID FRS2 Biochemical Activity physical 10650943 NA BioGRID GRB10 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, protein three hybrid, pull down, two hybrid direct interaction, physical, physical association 10871840, 15664450, 19648926, 7479769, 8621530, 9006901, 9506989 0.40, 0.58 BioGRID, IntAct, MINT GRB14 Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, bioluminescence resonance energy transfer physical, physical association 11726652, 16582879, 19648926, 24535599 0.40 BioGRID, IntAct, MINT GRB2 Affinity Capture-Western physical 9083103 NA BioGRID GRB7 Reconstituted Complex, Two-hybrid physical 10803466 NA BioGRID HACD3 Affinity Capture-Western physical 25687571 NA BioGRID HACD3 anti bait coimmunoprecipitation association 25687571 0.35 IntAct HGS Affinity Capture-Western physical 17445799 NA BioGRID HNRNPL Affinity Capture-RNA physical 28611215 NA BioGRID HRAS Biochemical Activity physical 3109943 NA BioGRID IGF1 competition binding, x-ray crystallography direct interaction, physical association 26027733, 8452530 0.40, 0.44 IntAct INPPL1 Affinity Capture-Western physical 12504111, 17620296 NA BioGRID INS x-ray crystallography direct interaction 23302862 0.44 IntAct INSL5 Affinity Capture-MS physical 28514442 NA BioGRID INSR Biochemical Activity, Reconstituted Complex, molecular sieving, protein kinase assay, x-ray crystallography direct interaction, phosphorylation reaction, physical 16957736, 18278056, 2033070, 23302862, 26853939 0.44, 0.73 BioGRID, IntAct INSRR Affinity Capture-Western physical 8916919 NA BioGRID IRF7 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct IRS1 Affinity Capture-Western, Biochemical Activity, Reconstituted Complex, Two-hybrid, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, pull down, two hybrid association, direct interaction, physical, physical association 11606564, 11781100, 16582879, 17167487, 25667086, 7499194, 7935368, 8626379, 8662806 0.35, 0.70 BioGRID, IntAct, MINT IRS2 Two-hybrid, pull down, two hybrid direct interaction, physical, physical association 8626379, 8662806 0.53 BioGRID, IntAct, MINT JAK1 Affinity Capture-Western physical 12456798 NA BioGRID JAK2 Affinity Capture-Western physical 12456798, 8912646 NA BioGRID KHDRBS1 Affinity Capture-Western physical 11604231 NA BioGRID KIF5A Affinity Capture-Western, anti bait coimmunoprecipitation association, physical 25687571 0.35 BioGRID, IntAct KRT31 Two-hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid physical, physical association 25416956 0.56 BioGRID, IntAct MAD2L1 imaging technique, two hybrid, two hybrid array, two hybrid prey pooling approach physical association 9092546, 0.46, 0.49 IntAct, MINT MAPK1 Affinity Capture-Western physical 11409918 NA BioGRID MAPK3 Affinity Capture-Western physical 11409918 NA BioGRID MARCH1 Affinity Capture-Western, Biochemical Activity physical 27577745 NA BioGRID MOK Affinity Capture-MS physical 23602568 NA BioGRID MPZL2 Affinity Capture-Western physical 28065597 NA BioGRID NTRK1 Affinity Capture-MS physical 25921289 NA BioGRID PIK3R1 fluorescent resonance energy transfer, pull down association, physical association 10500481, 11796522, 9593725 0.69 IntAct, MINT PLCG1 Protein-peptide, coimmunoprecipitation, cross-linking study, fluorescence microscopy, pull down colocalization, direct interaction, physical, physical association 11796522, 14568990, 22974441, 9593725 0.80 BioGRID, IntAct, MINT PON2 Affinity Capture-MS physical 26186194, 28514442 NA BioGRID PPM1A Affinity Capture-Western physical 28065597 NA BioGRID PPM1F Affinity Capture-Western physical 28065597 NA BioGRID PRKAA1 Affinity Capture-Western physical 25687571 NA BioGRID PRKAA2 Affinity Capture-Western, anti bait coimmunoprecipitation association, physical 25687571 0.35 BioGRID, IntAct PRKCD Affinity Capture-Western physical 11266508, 12031982 NA BioGRID PTPN1 Affinity Capture-Western, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation, bimolecular fluorescence complementation, bioluminescence resonance energy transfer, coimmunoprecipitation, filter binding, fluorescent resonance energy transfer, genetic interference, phosphatase assay, protein kinase assay, pull down, x-ray crystallography association, colocalization, dephosphorylation reaction, direct interaction, phosphorylation reaction, physical, physical association 11163213, 11506178, 11579209, 11726652, 12237455, 12634852, 14722096, 15588987, 16271887, 16582879, 16926280, 17092689, 17159996, 17481567, 19029027, 21806020, 8702689, 8999839 0.44, 0.98 BioGRID, IntAct, MINT PTPN11 Affinity Capture-Western, Reconstituted Complex, pull down association, physical, physical association 7493946, 8135823, 9593725 0.56 BioGRID, IntAct, MINT PTPN12 phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPN2 anti bait coimmunoprecipitation physical association 15192089 0.40 IntAct, MINT PTPN3 phosphatase assay dephosphorylation reaction 25728925 0.44 IntAct PTPN6 Affinity Capture-Western physical 7512963 NA BioGRID PTPRB phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRC phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRG phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRJ phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRK Affinity Capture-MS, phosphatase assay dephosphorylation reaction, physical 19167335, 26186194, 28514442 0.44 BioGRID, IntAct PTPRO phosphatase assay dephosphorylation reaction 19167335 0.44 IntAct PTPRR Affinity Capture-Western, Two-hybrid physical 28065597 NA BioGRID RASA1 Affinity Capture-Western, pull down physical, physical association 1331107, 9593725 0.40 BioGRID, IntAct, MINT RHOB fluorescence microscopy colocalization 14722096 0.27 IntAct, MINT SCGB1D1 Affinity Capture-MS physical 28514442 NA BioGRID SH2B1 Affinity Capture-Western, Reconstituted Complex, Two-hybrid, coimmunoprecipitation, two hybrid association, physical, physical association 10594240, 15767667, 9742218 0.48 BioGRID, IntAct, MINT SH2B2 Affinity Capture-Western, Two-hybrid physical 15031295, 17620296 NA BioGRID SHC1 Reconstituted Complex, Two-hybrid, pull down, two hybrid physical, physical association 10803466, 15629149, 7499194, 9593725 0.57 BioGRID, IntAct, MINT SMAD2 Affinity Capture-Western, Reconstituted Complex, Two-hybrid physical 9092546 NA BioGRID SNX1 Affinity Capture-Western physical 9819414 NA BioGRID SNX17 Affinity Capture-Western physical 23382219 NA BioGRID SNX2 Affinity Capture-Western physical 9819414 NA BioGRID SNX27 Affinity Capture-Western physical 23382219 NA BioGRID SNX4 Affinity Capture-Western physical 9819414 NA BioGRID SNX6 Affinity Capture-Western physical 11279102 NA BioGRID SOCS1 Affinity Capture-Western physical 11342531 NA BioGRID SOCS3 Affinity Capture-Western physical 12560330, 15514089 NA BioGRID SOCS6 Affinity Capture-Western physical 11342531 NA BioGRID SORBS1 Affinity Capture-Western physical 11374898 NA BioGRID SORBS1 anti bait coimmunoprecipitation physical association 11374898 0.40 IntAct SQSTM1 Affinity Capture-MS, Biochemical Activity physical 26043024, 9564850 NA BioGRID SSH1 Affinity Capture-Western physical 28065597 NA BioGRID STAT5A Affinity Capture-Western physical 12456798 NA BioGRID STAT5B Affinity Capture-Western, two hybrid physical, physical association 12456798, 9428692 0.37 BioGRID, IntAct, MINT STYX Two-hybrid physical 28065597 NA BioGRID SYNCRIP Biochemical Activity physical 11994298 NA BioGRID TEAD1 Two-hybrid, two hybrid array physical, physical association 21988832 0.37 BioGRID, IntAct TMEM17 Proximity Label-MS, proximity-dependent biotin identification association, physical 26638075 0.35 BioGRID, IntAct TRIM25 Affinity Capture-RNA physical 29117863 NA BioGRID UNC5CL Affinity Capture-MS physical 28514442 NA BioGRID VAV1 Reconstituted Complex physical 7535775 NA BioGRID VAV3 Affinity Capture-Western physical 11094073 NA BioGRID YWHAB two hybrid physical association 15629149 0.37 IntAct