Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PTPN11	9644	COSM6952316,	large_intestine	carcinoma	p.E110G	Substitution - Missense	12:112450509-112450509,	PATHOGENIC	0.99893	28481359
PTPN11	9644	COSM6919878,	upper_aerodigestive_tract	carcinoma	p.G483C	Substitution - Missense	12:112488510-112488510,	PATHOGENIC	0.99885	28481359
PTPN11	9644	COSM303867,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N308S	Substitution - Missense	12:112477720-112477720,	PATHOGENIC	0.99862	21680795
PTPN11	9644	COSM6912596,	central_nervous_system	glioma	p.G464A	Substitution - Missense	12:112488454-112488454,	PATHOGENIC	0.99859	28481359
PTPN11	9644	COSM6986171,	lung	carcinoma	p.G464C	Substitution - Missense	12:112488453-112488453,	PATHOGENIC	0.99853	28481359
PTPN11	9644	COSM6926209,	ovary	carcinoma	p.S404*	Substitution - Nonsense	12:112482192-112482192,	PATHOGENIC	0.99834	28481359
PTPN11	9644	COSM5945282,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G464D	Substitution - Missense	12:112488454-112488454,	PATHOGENIC	0.99833	27276561
PTPN11	9644	COSM13993,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T52S	Substitution - Missense	12:112450335-112450335,	PATHOGENIC	0.99819	15928039
PTPN11	9644	COSM13993,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T52S	Substitution - Missense	12:112450335-112450335,	PATHOGENIC	0.99819	15755284
PTPN11	9644	COSM5879377,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T52I	Substitution - Missense	12:112450335-112450335,	PATHOGENIC	0.99799	27288520
PTPN11	9644	COSM24612,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N308D	Substitution - Missense	12:112477719-112477719,	PATHOGENIC	0.9979	16533526
PTPN11	9644	COSM24612,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N308D	Substitution - Missense	12:112477719-112477719,	PATHOGENIC	0.9979	24030381
PTPN11	9644	COSM24612,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N308D	Substitution - Missense	12:112477719-112477719,	PATHOGENIC	0.9979	26648538
PTPN11	9644	COSM24612,	central_nervous_system	glioma	p.N308D	Substitution - Missense	12:112477719-112477719,	PATHOGENIC	0.9979	28481359
PTPN11	9644	COSM6291355,	kidney	carcinoma	p.N306S	Substitution - Missense	12:112477714-112477714,	PATHOGENIC	0.99783	28481359
PTPN11	9644	COSM6931944,	central_nervous_system	glioma	p.E176K	Substitution - Missense	12:112454564-112454564,	PATHOGENIC	0.99759	28481359
PTPN11	9644	COSM4641621,	pancreas	carcinoma	p.D180N	Substitution - Missense	12:112454576-112454576,	PATHOGENIC	0.99759	28481359
PTPN11	9644	COSM935282,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A461G	Substitution - Missense	12:112488445-112488445,	PATHOGENIC	0.99747	27276561
PTPN11	9644	COSM935282,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A461G	Substitution - Missense	12:112488445-112488445,	PATHOGENIC	0.99747	27276561
PTPN11	9644	COSM1287456,	skin	malignant_melanoma	p.A461T	Substitution - Missense	12:112488444-112488444,	PATHOGENIC	0.99744	26343386
PTPN11	9644	COSM1287456,	central_nervous_system	glioma	p.A461T	Substitution - Missense	12:112488444-112488444,	PATHOGENIC	0.99744	28481359
PTPN11	9644	COSM1287456,	central_nervous_system	glioma	p.A461T	Substitution - Missense	12:112488444-112488444,	PATHOGENIC	0.99744	28481359
PTPN11	9644	COSM170715,	large_intestine	carcinoma	p.T468M	Substitution - Missense	12:112488466-112488466,	PATHOGENIC	0.99731	28481359
PTPN11	9644	COSM170715,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T468M	Substitution - Missense	12:112488466-112488466,	PATHOGENIC	0.99731	23832011
PTPN11	9644	COSM5944168,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D106H	Substitution - Missense	12:112450496-112450496,	PATHOGENIC	0.99676	26124496
PTPN11	9644	COSM6931268,	lung	carcinoma	p.S321*	Substitution - Nonsense	12:112477885-112477885,	PATHOGENIC	0.99616	28481359
PTPN11	9644	COSM5610084,	skin	malignant_melanoma	p.T288I	Substitution - Missense	12:112477660-112477660,	PATHOGENIC	0.9956	26343386
PTPN11	9644	COSM13010,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60R	Substitution - Missense	12:112450358-112450358,	PATHOGENIC	0.99551	15928039
PTPN11	9644	COSM13010,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60R	Substitution - Missense	12:112450358-112450358,	PATHOGENIC	0.99551	27288520
PTPN11	9644	COSM13010,	lung	carcinoma	p.G60R	Substitution - Missense	12:112450358-112450358,	PATHOGENIC	0.99551	28481359
PTPN11	9644	COSM13010,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60R	Substitution - Missense	12:112450358-112450358,	PATHOGENIC	0.99551	23832011
PTPN11	9644	COSM13010,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G60R	Substitution - Missense	12:112450358-112450358,	PATHOGENIC	0.99551	19776760
PTPN11	9644	COSM13010,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60R	Substitution - Missense	12:112450358-112450358,	PATHOGENIC	0.99551	14644997
PTPN11	9644	COSM6955166,	large_intestine	carcinoma	p.W248*	Substitution - Nonsense	12:112456050-112456050,	PATHOGENIC	0.99512	28481359
PTPN11	9644	COSM6984753,	lung	carcinoma	p.E176V	Substitution - Missense	12:112454565-112454565,	PATHOGENIC	0.9949	28481359
PTPN11	9644	COSM5945280,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M311V	Substitution - Missense	12:112477728-112477728,	PATHOGENIC	0.99467	27276561
PTPN11	9644	COSM6978084,	lung	carcinoma	p.M355I	Substitution - Missense	12:112477988-112477988,	PATHOGENIC	0.99465	28481359
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	16358218
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	22238327
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	27276561
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	27288520
PTPN11	9644	COSM13016,	lung	carcinoma	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	28481359
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	15385933
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	19047918
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	16358218
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	14982869
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	16518851
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	14644997
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	19773259
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	24496301
PTPN11	9644	COSM13016,	soft_tissue	rhabdomyosarcoma	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	22142829
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	19776760
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	14982869
PTPN11	9644	COSM13016,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99423	17972951
PTPN11	9644	COSM4774836,	breast	carcinoma	p.D425H	Substitution - Missense	12:112486523-112486523,	PATHOGENIC	0.99418	24185512
PTPN11	9644	COSM20900,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61H	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99416	27276561
PTPN11	9644	COSM20900,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61H	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99416	19773259
PTPN11	9644	COSM20900,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61H	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99416	27276561
PTPN11	9644	COSM13037,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60A	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99416	27288520
PTPN11	9644	COSM13037,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60A	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99416	14644997
PTPN11	9644	COSM13037,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60A	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99416	27288520
PTPN11	9644	COSM20900,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61H	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99416	27276561
PTPN11	9644	COSM20900,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61H	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99416	15842656
PTPN11	9644	COSM20900,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61H	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99416	27276561
PTPN11	9644	COSM13037,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60A	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99416	27288520
PTPN11	9644	COSM20900,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61H	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99416	27276561
PTPN11	9644	COSM20900,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61H	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99416	19776760
PTPN11	9644	COSM13037,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60A	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99416	27276561
PTPN11	9644	COSM383114,	lung	carcinoma	p.D425Y	Substitution - Missense	12:112486523-112486523,	PATHOGENIC	0.99359	28481359
PTPN11	9644	COSM13032,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N58Y	Substitution - Missense	12:112450352-112450352,	PATHOGENIC	0.99358	23832011
PTPN11	9644	COSM13032,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N58Y	Substitution - Missense	12:112450352-112450352,	PATHOGENIC	0.99358	27288520
PTPN11	9644	COSM13032,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N58Y	Substitution - Missense	12:112450352-112450352,	PATHOGENIC	0.99358	14982869
PTPN11	9644	COSM13032,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N58Y	Substitution - Missense	12:112450352-112450352,	PATHOGENIC	0.99358	27276561
PTPN11	9644	COSM13032,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N58Y	Substitution - Missense	12:112450352-112450352,	PATHOGENIC	0.99358	27288520
PTPN11	9644	COSM13032,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N58Y	Substitution - Missense	12:112450352-112450352,	PATHOGENIC	0.99358	16533526
PTPN11	9644	COSM13032,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N58Y	Substitution - Missense	12:112450352-112450352,	PATHOGENIC	0.99358	23832011
PTPN11	9644	COSM13032,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N58Y	Substitution - Missense	12:112450352-112450352,	PATHOGENIC	0.99358	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	23832011
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	12717436
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	14982869
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	19776760
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27276561
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15755284
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	12717436
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27683039
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	12717436
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27276561
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27276561
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	23832011
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	19047918
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27276561
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15755284
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27276561
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27359055
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	12717436
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	14644997
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	16358218
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	26980726
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	16518851
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	19874312
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27276561
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	14644997
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27881874
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	16533526
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	19776760
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	19047918
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	19773259
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	25616283
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	16358218
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	17910045
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	19773259
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	16358218
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15842656
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27276561
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	12717436
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	19047918
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	central_nervous_system	glioma	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	28481359
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	19047918
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	26980726
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	25616283
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	23832011
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	19776760
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	16358218
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	23832011
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	21680795
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	19047918
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	18925961
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	12717436
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27276561
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	central_nervous_system	glioma	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	28481359
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	15928039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	19047918
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	21680795
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27288520
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27881874
PTPN11	9644	COSM13011,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	27683039
PTPN11	9644	COSM13028,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G60V	Substitution - Missense	12:112450359-112450359,	PATHOGENIC	0.99353	27881874
PTPN11	9644	COSM13011,	skin	carcinoma	p.D61Y	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.99353	28984303
PTPN11	9644	COSM1948742,	genital_tract	germ_cell_tumour	p.N58S	Substitution - Missense	12:112450353-112450353,	PATHOGENIC	0.99344	28481359
PTPN11	9644	COSM1948742,	breast	carcinoma	p.N58S	Substitution - Missense	12:112450353-112450353,	PATHOGENIC	0.99344	25695693
PTPN11	9644	COSM1948742,	prostate	carcinoma	p.N58S	Substitution - Missense	12:112450353-112450353,	PATHOGENIC	0.99344	20579941
PTPN11	9644	COSM4384772,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99326	24030381
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	27288520
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	24496301
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	16358218
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	27288520
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	15928039
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	21901340
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	15928039
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	17972951
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	27276561
PTPN11	9644	COSM4384772,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99326	27288520
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	23832011
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	15928039
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	15928039
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	24496301
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	27276561
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	27288520
PTPN11	9644	COSM4384772,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99326	27288520
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	12717436
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	17972951
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	19047918
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	27276561
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	19047918
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	15928039
PTPN11	9644	COSM13027,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G503A	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99326	27683039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	12717436
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	21901340
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15385933
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14982869
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16533526
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16358218
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14644997
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM1579785,	skin	adnexal_tumour	p.V78I	Substitution - Missense	12:112450412-112450412,	PATHOGENIC	0.99278	27311873
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16358218
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14982869
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15009076
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27288520
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	21901340
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	21901340
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16358218
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15842656
PTPN11	9644	COSM13000,	central_nervous_system	glioma	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	28481359
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27288520
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19874312
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	17972951
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	25616283
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	17972951
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14982869
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27683039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15755284
PTPN11	9644	COSM13000,	central_nervous_system	glioma	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	28481359
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27288520
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15385933
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27288520
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16518851
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15755284
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	12717436
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16518851
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19798502
PTPN11	9644	COSM13000,	central_nervous_system	glioma	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	28481359
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16358218
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16358218
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	12717436
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19047918
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19874312
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	21901340
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	20432758
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14982869
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	25616283
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27881874
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14982869
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27276561
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	21901340
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27288520
PTPN11	9644	COSM13000,	skin	malignant_melanoma	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	26343386
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14644997
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	16358218
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15755284
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14644997
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	27288520
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	23832011
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	12717436
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	14644997
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	12717436
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	19773259
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13000,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	12:112450406-112450406,	PATHOGENIC	0.99278	15928039
PTPN11	9644	COSM13012,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.9927	14644997
PTPN11	9644	COSM13012,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.9927	15842656
PTPN11	9644	COSM13012,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.9927	27288520
PTPN11	9644	COSM13012,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.9927	27276561
PTPN11	9644	COSM13012,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.9927	27276561
PTPN11	9644	COSM13012,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.9927	27288520
PTPN11	9644	COSM6931943,	central_nervous_system	glioma	p.?	Unknown	12:112446399-112446399,	PATHOGENIC	0.9927	28481359
PTPN11	9644	COSM13012,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.9927	27288520
PTPN11	9644	COSM13012,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N	Substitution - Missense	12:112450361-112450361,	PATHOGENIC	0.9927	27881874
PTPN11	9644	COSM546362,	large_intestine	carcinoma	p.V428M	Substitution - Missense	12:112486532-112486532,	PATHOGENIC	0.99269	28481359
PTPN11	9644	COSM1706297,	skin	malignant_melanoma	p.D425N	Substitution - Missense	12:112486523-112486523,	PATHOGENIC	0.99269	28481359
PTPN11	9644	COSM546362,	urinary_tract	carcinoma	p.V428M	Substitution - Missense	12:112486532-112486532,	PATHOGENIC	0.99269	28481359
PTPN11	9644	COSM546362,	biliary_tract	carcinoma	p.V428M	Substitution - Missense	12:112486532-112486532,	PATHOGENIC	0.99269	29360550
PTPN11	9644	COSM6920652,	NS	carcinoma	p.G133C	Substitution - Missense	12:112453259-112453259,	PATHOGENIC	0.99268	28481359
PTPN11	9644	COSM6984534,	endometrium	carcinoma	p.A16T	Substitution - Missense	12:112446307-112446307,	PATHOGENIC	0.99253	28481359
PTPN11	9644	COSM5945283,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503W	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99247	27276561
PTPN11	9644	COSM14271,	biliary_tract	carcinoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	29360550
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27276561
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27276561
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27276561
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27288520
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27288520
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	23832011
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	15928039
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	15928039
PTPN11	9644	COSM14271,	soft_tissue	rhabdomyosarcoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	26822237
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27288520
PTPN11	9644	COSM14271,	urinary_tract	carcinoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	28481359
PTPN11	9644	COSM14271,	breast	carcinoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	25850943
PTPN11	9644	COSM14271,	stomach	carcinoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	25656989
PTPN11	9644	COSM14271,	biliary_tract	carcinoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	29360550
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	19776760
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	15928039
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27276561
PTPN11	9644	COSM14271,	small_intestine	carcinoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	24797764
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	15928039
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	25616283
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	15834506
PTPN11	9644	COSM14271,	NS	malignant_melanoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	25148578
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27276561
PTPN11	9644	COSM14271,	lung	carcinoma	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	18948947
PTPN11	9644	COSM14271,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503V	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99247	27276561
PTPN11	9644	COSM5991633,	skin	adnexal_tumour	p.D64N	Substitution - Missense	12:112450370-112450370,	PATHOGENIC	0.99243	27311873
PTPN11	9644	COSM5991633,	prostate	carcinoma	p.D64N	Substitution - Missense	12:112450370-112450370,	PATHOGENIC	0.99243	20579941
PTPN11	9644	COSM6006328,	skin	adnexal_tumour	p.E69Q	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.99234	27287813
PTPN11	9644	COSM6006459,	NS	malignant_melanoma	p.R498L	Substitution - Missense	12:112489069-112489069,	PATHOGENIC	0.99204	25148578
PTPN11	9644	COSM6006459,	lung	carcinoma	p.R498L	Substitution - Missense	12:112489069-112489069,	PATHOGENIC	0.99204	28481359
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	27288520
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	23832011
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	27276561
PTPN11	9644	COSM6917865,	skin	malignant_melanoma	p.A122T	Substitution - Missense	12:112453226-112453226,	PATHOGENIC	0.99171	28481359
PTPN11	9644	COSM5945278,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E139K	Substitution - Missense	12:112453277-112453277,	PATHOGENIC	0.99171	27276561
PTPN11	9644	COSM6985191,	endometrium	carcinoma	p.G133D	Substitution - Missense	12:112453260-112453260,	PATHOGENIC	0.99171	28481359
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	27288520
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	17330262
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	12717436
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	12717436
PTPN11	9644	COSM13026,	skin	malignant_melanoma	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	26343386
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	16358218
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	23832011
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	15755284
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	27276561
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	15085150
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	19798502
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	23832011
PTPN11	9644	COSM13026,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76A	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99171	27276561
PTPN11	9644	COSM6947166,	large_intestine	carcinoma	p.N37T	Substitution - Missense	12:112446371-112446371,	PATHOGENIC	0.99169	28481359
PTPN11	9644	COSM6976655,	central_nervous_system	glioma	p.G115E	Substitution - Missense	12:112453206-112453206,	PATHOGENIC	0.99165	28481359
PTPN11	9644	COSM5945275,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61A	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99161	27276561
PTPN11	9644	COSM5945275,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61A	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99161	29386642
PTPN11	9644	COSM14259,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99155	16358218
PTPN11	9644	COSM13021,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503E	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99155	15725481
PTPN11	9644	COSM14259,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99155	27276561
PTPN11	9644	COSM6006456,	NS	malignant_melanoma	p.V505I	Substitution - Missense	12:112489089-112489089,	PATHOGENIC	0.99155	25148578
PTPN11	9644	COSM14259,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99155	27276561
PTPN11	9644	COSM6006456,	large_intestine	carcinoma	p.V505I	Substitution - Missense	12:112489089-112489089,	PATHOGENIC	0.99155	28481359
PTPN11	9644	COSM14259,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99155	27276561
PTPN11	9644	COSM13021,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503E	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99155	16358218
PTPN11	9644	COSM5879379,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R501K	Substitution - Missense	12:112489078-112489078,	PATHOGENIC	0.99155	27288520
PTPN11	9644	COSM13021,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503E	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99155	27276561
PTPN11	9644	COSM13021,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503E	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99155	27486981
PTPN11	9644	COSM14259,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99155	27486981
PTPN11	9644	COSM13021,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503E	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99155	27486981
PTPN11	9644	COSM14259,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99155	24056718
PTPN11	9644	COSM13021,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503E	Substitution - Missense	12:112489084-112489084,	PATHOGENIC	0.99155	27288520
PTPN11	9644	COSM14259,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503R	Substitution - Missense	12:112489083-112489083,	PATHOGENIC	0.99155	27288520
PTPN11	9644	COSM1948744,	central_nervous_system	glioma	p.A72S	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.99143	28481359
PTPN11	9644	COSM1948744,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72S	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.99143	27359055
PTPN11	9644	COSM1948744,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72S	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.99143	25407606
PTPN11	9644	COSM6006457,	NS	malignant_melanoma	p.R498Q	Substitution - Missense	12:112489069-112489069,	PATHOGENIC	0.99107	25148578
PTPN11	9644	COSM6006457,	NS	malignant_melanoma	p.R498Q	Substitution - Missense	12:112489069-112489069,	PATHOGENIC	0.99107	25148578
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	16518851
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	15085150
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	12717436
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	19776760
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	27276561
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	16358218
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	27881874
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	19773259
PTPN11	9644	COSM13025,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76V	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99072	19776760
PTPN11	9644	COSM5879378,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q79R	Substitution - Missense	12:112450416-112450416,	PATHOGENIC	0.99067	27276561
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16518851
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	14644997
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	27288520
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16518851
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	12717436
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	15928039
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	15928039
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	15928039
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	27276561
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16358218
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16358218
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	27276561
PTPN11	9644	COSM13017,	central_nervous_system	glioma	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	28481359
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	27276561
PTPN11	9644	COSM5879378,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q79R	Substitution - Missense	12:112450416-112450416,	PATHOGENIC	0.99067	29386642
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	15385933
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	27276561
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	24338706
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	15928039
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	15928039
PTPN11	9644	COSM5879378,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q79R	Substitution - Missense	12:112450416-112450416,	PATHOGENIC	0.99067	27288520
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16518851
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	21901340
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	14982869
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	15928039
PTPN11	9644	COSM13017,	central_nervous_system	glioma	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	28481359
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	19047918
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16358218
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	27288520
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	19047918
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16518851
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	19047918
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16358218
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	27276561
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	14644997
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	16358218
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	23832011
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	24338706
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	23832011
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	15385933
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	14644997
PTPN11	9644	COSM5879378,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q79R	Substitution - Missense	12:112450416-112450416,	PATHOGENIC	0.99067	27276561
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	14982869
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	17972951
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	27276561
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	23832011
PTPN11	9644	COSM13017,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	12:112450407-112450407,	PATHOGENIC	0.99067	14644997
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27276561
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	19047918
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	21390130
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	16518851
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27288520
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	23832011
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27288520
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	15928039
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27683039
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	19047918
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	16358218
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27276561
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	15928039
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	14982869
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	16358218
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	16358218
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	15928039
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	16518851
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	12717436
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	14644997
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	12717436
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27276561
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	24496301
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27288520
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	16518851
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27881874
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	21390130
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27276561
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	29386642
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	26980726
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	23832011
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	19874312
PTPN11	9644	COSM4384770,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69V	Substitution - Missense	12:112450386-112450386,	PATHOGENIC	0.99061	24030381
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	17910045
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	15928039
PTPN11	9644	COSM6006458,	NS	malignant_melanoma	p.K70*	Substitution - Nonsense	12:112450388-112450388,	PATHOGENIC	0.99061	25148578
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	19047918
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	16518851
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	27276561
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	15725481
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	23832011
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	15928039
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	23832011
PTPN11	9644	COSM13022,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99061	15928039
PTPN11	9644	COSM14269,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61G	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99056	16533526
PTPN11	9644	COSM14269,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61G	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99056	27276561
PTPN11	9644	COSM14269,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61G	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99056	27288520
PTPN11	9644	COSM14269,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61G	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99056	27288520
PTPN11	9644	COSM14269,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61G	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99056	15928039
PTPN11	9644	COSM14269,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61G	Substitution - Missense	12:112450362-112450362,	PATHOGENIC	0.99056	26980726
PTPN11	9644	COSM1658770,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q506P	Substitution - Missense	12:112489093-112489093,	PATHOGENIC	0.9903	23702683
PTPN11	9644	COSM1658770,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q506P	Substitution - Missense	12:112489093-112489093,	PATHOGENIC	0.9903	27288520
PTPN11	9644	COSM13038,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Y63C	Substitution - Missense	12:112450368-112450368,	PATHOGENIC	0.99015	27288520
PTPN11	9644	COSM13038,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Y63C	Substitution - Missense	12:112450368-112450368,	PATHOGENIC	0.99015	14644997
PTPN11	9644	COSM5351681,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D556Y	Substitution - Missense	12:112502210-112502210,	PATHOGENIC	0.99001	25381129
PTPN11	9644	COSM6937145,	central_nervous_system	glioma	p.R289G	Substitution - Missense	12:112477662-112477662,	PATHOGENIC	0.98987	28481359
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27288520
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	17972951
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	17330262
PTPN11	9644	COSM13014,	central_nervous_system	glioma	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	17972951
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	21680795
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27288520
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	24056718
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	19047918
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	17972951
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	12717436
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	17910045
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27683039
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	12717436
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	22658276
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	14644997
PTPN11	9644	COSM13013,	oesophagus	carcinoma	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	20237506
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	14982869
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	29386642
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	14644997
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	14982869
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27288520
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27288520
PTPN11	9644	COSM13013,	breast	carcinoma	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27288520
PTPN11	9644	COSM13013,	soft_tissue	rhabdomyosarcoma	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	19681119
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	12717436
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	14982869
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	21680795
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	24030381
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	21901340
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	12717436
PTPN11	9644	COSM13014,	central_nervous_system	glioma	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	21390130
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	16358218
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	15385933
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	15928039
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	16533526
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	12717436
PTPN11	9644	COSM13013,	breast	carcinoma	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27284958
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	23832011
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	17330262
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27288520
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	16358218
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13013,	autonomic_ganglia	neuroblastoma	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	19874312
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27288520
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	15928039
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27881874
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	15842656
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	23832011
PTPN11	9644	COSM13014,	small_intestine	carcinoma	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	24797764
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	16358218
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13014,	soft_tissue	rhabdomyosarcoma	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	16518851
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27683039
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	15928039
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27288520
PTPN11	9644	COSM13013,	skin	adnexal_tumour	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	27311873
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27276561
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	16358218
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	25407606
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	15928039
PTPN11	9644	COSM13013,	central_nervous_system	glioma	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13013,	central_nervous_system	glioma	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27534895
PTPN11	9644	COSM13013,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	12717436
PTPN11	9644	COSM13014,	breast	carcinoma	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13013,	central_nervous_system	glioma	p.E69K	Substitution - Missense	12:112450385-112450385,	PATHOGENIC	0.98978	28481359
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	14644997
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	27534895
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	15928039
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	24030381
PTPN11	9644	COSM13014,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T	Substitution - Missense	12:112450394-112450394,	PATHOGENIC	0.98978	17972951
PTPN11	9644	COSM5424306,	central_nervous_system	glioma	p.F285S	Substitution - Missense	12:112477651-112477651,	PATHOGENIC	0.9894	28481359
PTPN11	9644	COSM5424306,	central_nervous_system	glioma	p.F285S	Substitution - Missense	12:112477651-112477651,	PATHOGENIC	0.9894	28481359
PTPN11	9644	COSM5424306,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F285S	Substitution - Missense	12:112477651-112477651,	PATHOGENIC	0.9894	27534895
PTPN11	9644	COSM5424306,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F285S	Substitution - Missense	12:112477651-112477651,	PATHOGENIC	0.9894	27276561
PTPN11	9644	COSM5424306,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F285S	Substitution - Missense	12:112477651-112477651,	PATHOGENIC	0.9894	27276561
PTPN11	9644	COSM1318059,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510L	Substitution - Missense	12:112489105-112489105,	PATHOGENIC	0.98912	27288520
PTPN11	9644	COSM1318059,	central_nervous_system	glioma	p.Q510L	Substitution - Missense	12:112489105-112489105,	PATHOGENIC	0.98912	28481359
PTPN11	9644	COSM1318059,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510L	Substitution - Missense	12:112489105-112489105,	PATHOGENIC	0.98912	27359055
PTPN11	9644	COSM4603683,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.M504V	Substitution - Missense	12:112489086-112489086,	PATHOGENIC	0.98905	25407606
PTPN11	9644	COSM6962773,	central_nervous_system	glioma	p.G539E	Substitution - Missense	12:112502160-112502160,	PATHOGENIC	0.98859	28481359
PTPN11	9644	COSM6974755,	large_intestine	carcinoma	p.T356A	Substitution - Missense	12:112477989-112477989,	PATHOGENIC	0.98855	28481359
PTPN11	9644	COSM6956180,	lung	carcinoma	p.D485G	Substitution - Missense	12:112489030-112489030,	PATHOGENIC	0.98844	28481359
PTPN11	9644	COSM6978973,	ovary	germ_cell_tumour	p.Q500E	Substitution - Missense	12:112489074-112489074,	PATHOGENIC	0.98775	28954785
PTPN11	9644	COSM6978973,	lung	carcinoma	p.Q500E	Substitution - Missense	12:112489074-112489074,	PATHOGENIC	0.98775	28481359
PTPN11	9644	COSM5945276,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Y62D	Substitution - Missense	12:112450364-112450364,	PATHOGENIC	0.98766	27276561
PTPN11	9644	COSM13036,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T507K	Substitution - Missense	12:112489096-112489096,	PATHOGENIC	0.98763	27276561
PTPN11	9644	COSM13036,	central_nervous_system	glioma	p.T507K	Substitution - Missense	12:112489096-112489096,	PATHOGENIC	0.98763	28481359
PTPN11	9644	COSM13036,	salivary_gland	carcinoma	p.T507K	Substitution - Missense	12:112489096-112489096,	PATHOGENIC	0.98763	26053092
PTPN11	9644	COSM13036,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T507K	Substitution - Missense	12:112489096-112489096,	PATHOGENIC	0.98763	14982869
PTPN11	9644	COSM13031,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q510K	Substitution - Missense	12:112489104-112489104,	PATHOGENIC	0.98763	14982869
PTPN11	9644	COSM13036,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T507K	Substitution - Missense	12:112489096-112489096,	PATHOGENIC	0.98763	27288520
PTPN11	9644	COSM13031,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.Q510K	Substitution - Missense	12:112489104-112489104,	PATHOGENIC	0.98763	19776760
PTPN11	9644	COSM5945277,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72G	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98687	27276561
PTPN11	9644	COSM5945277,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72G	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98687	27276561
PTPN11	9644	COSM6438174,	large_intestine	carcinoma	p.Q79H	Substitution - Missense	12:112450417-112450417,	PATHOGENIC	0.98687	27756406
PTPN11	9644	COSM5945277,	central_nervous_system	glioma	p.A72G	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98687	28481359
PTPN11	9644	COSM5945277,	central_nervous_system	glioma	p.A72G	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98687	28481359
PTPN11	9644	COSM6978832,	large_intestine	carcinoma	p.P454S	Substitution - Missense	12:112486610-112486610,	PATHOGENIC	0.98649	28481359
PTPN11	9644	COSM6922858,	NS	malignant_melanoma	p.H426Y	Substitution - Missense	12:112486526-112486526,	PATHOGENIC	0.98649	28481359
PTPN11	9644	COSM6975660,	lung	carcinoma	p.H419Y	Substitution - Missense	12:112486505-112486505,	PATHOGENIC	0.98649	28481359
PTPN11	9644	COSM4514583,	NS	malignant_melanoma	p.P33S	Substitution - Missense	12:112446358-112446358,	PATHOGENIC	0.98609	28481359
PTPN11	9644	COSM5610086,	skin	malignant_melanoma	p.S44F	Substitution - Missense	12:112446392-112446392,	PATHOGENIC	0.98609	26343386
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	27276561
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	20237506
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	23832011
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	15009076
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	15725481
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	15385933
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	27276561
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	17972951
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	27276561
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	27276561
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	17910045
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	22237106
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	22658276
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	17910045
PTPN11	9644	COSM13019,	skin	carcinoma	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	28984303
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	16358218
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	23832011
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	27276561
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	16358218
PTPN11	9644	COSM13019,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T73I	Substitution - Missense	12:112450398-112450398,	PATHOGENIC	0.98608	27276561
PTPN11	9644	COSM13035,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72D	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98595	27276561
PTPN11	9644	COSM13035,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72D	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98595	14982869
PTPN11	9644	COSM13035,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72D	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98595	16518851
PTPN11	9644	COSM13035,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72D	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98595	16518851
PTPN11	9644	COSM13035,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72D	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98595	27276561
PTPN11	9644	COSM13035,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72D	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98595	24056718
PTPN11	9644	COSM6981058,	NS	carcinoma	p.P101S	Substitution - Missense	12:112450481-112450481,	PATHOGENIC	0.9859	28481359
PTPN11	9644	COSM20901,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502A	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98586	26648538
PTPN11	9644	COSM20901,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502A	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98586	27276561
PTPN11	9644	COSM20901,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502A	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98586	15842656
PTPN11	9644	COSM20901,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502A	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98586	27276561
PTPN11	9644	COSM20901,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502A	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98586	27276561
PTPN11	9644	COSM20901,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502A	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98586	27288520
PTPN11	9644	COSM20901,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502A	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98586	27276561
PTPN11	9644	COSM6968448,	ovary	carcinoma	p.A16V	Substitution - Missense	12:112446308-112446308,	PATHOGENIC	0.98577	28481359
PTPN11	9644	COSM13039,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450391-112450391,	PATHOGENIC	0.98514	14644997
PTPN11	9644	COSM13039,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450391-112450391,	PATHOGENIC	0.98514	27276561
PTPN11	9644	COSM13039,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450391-112450391,	PATHOGENIC	0.98514	27288520
PTPN11	9644	COSM13039,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450391-112450391,	PATHOGENIC	0.98514	26980726
PTPN11	9644	COSM13039,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450391-112450391,	PATHOGENIC	0.98514	26124496
PTPN11	9644	COSM13039,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450391-112450391,	PATHOGENIC	0.98514	17972951
PTPN11	9644	COSM13039,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450391-112450391,	PATHOGENIC	0.98514	26980726
PTPN11	9644	COSM13039,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.F71L	Substitution - Missense	12:112450391-112450391,	PATHOGENIC	0.98514	27683039
PTPN11	9644	COSM14258,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502T	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98501	16358218
PTPN11	9644	COSM4498618,	breast	carcinoma	p.Q175*	Substitution - Nonsense	12:112453385-112453385,	PATHOGENIC	0.98383	28481359
PTPN11	9644	COSM5610080,	skin	malignant_melanoma	p.P38H	Substitution - Missense	12:112446374-112446374,	PATHOGENIC	0.98377	26343386
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27288520
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	19776760
PTPN11	9644	COSM13023,	salivary_gland	carcinoma	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	28481359
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	24030381
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	26980726
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27276561
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27276561
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27276561
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27881874
PTPN11	9644	COSM13023,	breast	carcinoma	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27284958
PTPN11	9644	COSM13023,	stomach	carcinoma	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	28481359
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27276561
PTPN11	9644	COSM13023,	lung	carcinoma	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	18948947
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	15385933
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27534895
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27276561
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27276561
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27288520
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	17910045
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27276561
PTPN11	9644	COSM13023,	skin	adnexal_tumour	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27311873
PTPN11	9644	COSM13023,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502L	Substitution - Missense	12:112489081-112489081,	PATHOGENIC	0.98376	27288520
PTPN11	9644	COSM6935843,	central_nervous_system	glioma	p.H196Y	Substitution - Missense	12:112454624-112454624,	PATHOGENIC	0.98308	28481359
PTPN11	9644	COSM4990202,	skin	carcinoma	p.Q211*	Substitution - Nonsense	12:112454669-112454669,	PATHOGENIC	0.98308	25589618
PTPN11	9644	COSM6951923,	salivary_gland	carcinoma	p.P201S	Substitution - Missense	12:112454639-112454639,	PATHOGENIC	0.98308	28481359
PTPN11	9644	COSM13020,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	19776760
PTPN11	9644	COSM13020,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	15725481
PTPN11	9644	COSM13020,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	21901340
PTPN11	9644	COSM13020,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	27276561
PTPN11	9644	COSM13020,	genital_tract	germ_cell_tumour	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	28481359
PTPN11	9644	COSM13020,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	14982869
PTPN11	9644	COSM13020,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	17330262
PTPN11	9644	COSM13020,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	27683039
PTPN11	9644	COSM13020,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.S502P	Substitution - Missense	12:112489080-112489080,	PATHOGENIC	0.98301	27276561
PTPN11	9644	COSM13034,	skin	malignant_melanoma	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	25769001
PTPN11	9644	COSM13034,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	14982869
PTPN11	9644	COSM13034,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	27276561
PTPN11	9644	COSM13034,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	27276561
PTPN11	9644	COSM13033,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P491S	Substitution - Missense	12:112489047-112489047,	PATHOGENIC	0.98286	27276561
PTPN11	9644	COSM13033,	central_nervous_system	glioma	p.P491S	Substitution - Missense	12:112489047-112489047,	PATHOGENIC	0.98286	28481359
PTPN11	9644	COSM13034,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	14982869
PTPN11	9644	COSM13034,	central_nervous_system	glioma	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	28481359
PTPN11	9644	COSM13034,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	26124496
PTPN11	9644	COSM13034,	skin	malignant_melanoma	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	25769001
PTPN11	9644	COSM13034,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	27276561
PTPN11	9644	COSM13034,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.P491L	Substitution - Missense	12:112489048-112489048,	PATHOGENIC	0.98286	27276561
PTPN11	9644	COSM13033,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.P491S	Substitution - Missense	12:112489047-112489047,	PATHOGENIC	0.98286	14982869
PTPN11	9644	COSM13033,	oesophagus	carcinoma	p.P491S	Substitution - Missense	12:112489047-112489047,	PATHOGENIC	0.98286	24686850
PTPN11	9644	COSM6944223,	lung	carcinoma	p.V25I	Substitution - Missense	12:112446334-112446334,	PATHOGENIC	0.98252	28481359
PTPN11	9644	COSM6914153,	soft_tissue	malignant_fibrous_histiocytoma-pleomorphic_sarcoma	p.V490A	Substitution - Missense	12:112489045-112489045,	PATHOGENIC	0.98206	28481359
PTPN11	9644	COSM6438175,	large_intestine	carcinoma	p.H85Y	Substitution - Missense	12:112450433-112450433,	PATHOGENIC	0.98036	27756406
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	21901340
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27534895
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	19047918
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	19047918
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	15928039
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	23832011
PTPN11	9644	COSM13015,	central_nervous_system	glioma	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	28481359
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14644997
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	15928039
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	26980726
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	15928039
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	21680795
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14644997
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	17910045
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	15755284
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	20237506
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	23832011
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14644997
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	15385933
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	16358218
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	21680795
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	24030381
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27288520
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14982869
PTPN11	9644	COSM13015,	large_intestine	carcinoma	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27756406
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	19047918
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27881874
PTPN11	9644	COSM13015,	central_nervous_system	glioma	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	28481359
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	large_intestine	carcinoma	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27756406
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	21901340
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	16358218
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	20237506
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27683039
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27462774
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27288520
PTPN11	9644	COSM13015,	central_nervous_system	glioma	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	28481359
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27359055
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27288520
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27683039
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14982869
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	19047918
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14982869
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	23832011
PTPN11	9644	COSM13015,	thyroid	carcinoma	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	26971368
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14982869
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	12717436
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	15928039
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	15385933
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14982869
PTPN11	9644	COSM13015,	central_nervous_system	glioma	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	28481359
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	14644997
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	23832011
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	16518851
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	19047918
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27534895
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27276561
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	17972951
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	17972951
PTPN11	9644	COSM13015,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72V	Substitution - Missense	12:112450395-112450395,	PATHOGENIC	0.98019	27683039
PTPN11	9644	COSM6916078,	NS	malignant_melanoma	p.P101L	Substitution - Missense	12:112450482-112450482,	PATHOGENIC	0.98017	28481359
PTPN11	9644	COSM935281,	endometrium	carcinoma	p.R384C	Substitution - Missense	12:112482131-112482131,	PATHOGENIC	0.97947	28481359
PTPN11	9644	COSM6978256,	endometrium	carcinoma	p.S548F	Substitution - Missense	12:112502187-112502187,	PATHOGENIC	0.9793	28481359
PTPN11	9644	COSM6914105,	prostate	carcinoma	p.R351Q	Substitution - Missense	12:112477975-112477975,	PATHOGENIC	0.97766	28481359
PTPN11	9644	COSM5480987,	lung	carcinoma	p.V382I	Substitution - Missense	12:112482125-112482125,	PATHOGENIC	0.97726	28481359
PTPN11	9644	COSM6925551,	skin	carcinoma	p.K590R	Substitution - Missense	12:112504751-112504751,	PATHOGENIC	0.97707	28481359
PTPN11	9644	COSM5576074,	stomach	carcinoma	p.R173H	Substitution - Missense	12:112453380-112453380,	PATHOGENIC	0.9761	26489445
PTPN11	9644	COSM5985343,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T42A	Substitution - Missense	12:112446385-112446385,	PATHOGENIC	0.97546	26438511
PTPN11	9644	COSM5985343,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.T42A	Substitution - Missense	12:112446385-112446385,	PATHOGENIC	0.97546	26438511
PTPN11	9644	COSM1645531,	large_intestine	carcinoma	p.R220C	Substitution - Missense	12:112455965-112455965,	PATHOGENIC	0.97463	23700467
PTPN11	9644	COSM6907822,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.N319N	Substitution - coding silent	12:112477880-112477880,	PATHOGENIC	0.97451	29386642
PTPN11	9644	COSM22468,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.R152H	Substitution - Missense	12:112453317-112453317,	PATHOGENIC	0.97221	16518851
PTPN11	9644	COSM1948768,	skin	adnexal_tumour	p.R527H	Substitution - Missense	12:112489156-112489156,	PATHOGENIC	0.97134	27311873
PTPN11	9644	COSM1948768,	breast	other	p.R527H	Substitution - Missense	12:112489156-112489156,	PATHOGENIC	0.97134	26832993
PTPN11	9644	COSM5945281,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D437N	Substitution - Missense	12:112486559-112486559,	PATHOGENIC	0.97006	27276561
PTPN11	9644	COSM5762918,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G268S	Substitution - Missense	12:112472989-112472989,	PATHOGENIC	0.96999	27127180
PTPN11	9644	COSM6946471,	large_intestine	carcinoma	p.R465W	Substitution - Missense	12:112488456-112488456,	PATHOGENIC	0.96921	28481359
PTPN11	9644	COSM6963617,	breast	carcinoma	p.E69D	Substitution - Missense	12:112450387-112450387,	PATHOGENIC	0.96777	28481359
PTPN11	9644	COSM1318058,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510H	Substitution - Missense	12:112489106-112489106,	PATHOGENIC	0.96639	27288520
PTPN11	9644	COSM1318058,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510H	Substitution - Missense	12:112489106-112489106,	PATHOGENIC	0.96639	27276561
PTPN11	9644	COSM1318058,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510H	Substitution - Missense	12:112489106-112489106,	PATHOGENIC	0.96639	27276561
PTPN11	9644	COSM6950327,	NS	carcinoma	p.I449F	Substitution - Missense	12:112486595-112486595,	PATHOGENIC	0.96636	28481359
PTPN11	9644	COSM6955165,	large_intestine	carcinoma	p.G163D	Substitution - Missense	12:112453350-112453350,	PATHOGENIC	0.9635	28481359
PTPN11	9644	COSM201196,	large_intestine	carcinoma	p.E123D	Substitution - Missense	12:112453231-112453231,	PATHOGENIC	0.96327	28481359
PTPN11	9644	COSM201196,	endometrium	carcinoma	p.E123D	Substitution - Missense	12:112453231-112453231,	PATHOGENIC	0.96327	28481359
PTPN11	9644	COSM201196,	penis	carcinoma	p.E123D	Substitution - Missense	12:112453231-112453231,	PATHOGENIC	0.96327	28481359
PTPN11	9644	COSM5945273,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N58K	Substitution - Missense	12:112450354-112450354,	PATHOGENIC	0.96297	27276561
PTPN11	9644	COSM1358901,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.R512Q	Substitution - Missense	12:112489111-112489111,	PATHOGENIC	0.96198	27288520
PTPN11	9644	COSM1358901,	penis	carcinoma	p.R512Q	Substitution - Missense	12:112489111-112489111,	PATHOGENIC	0.96198	28481359
PTPN11	9644	COSM13018,	central_nervous_system	glioma	p.E139D	Substitution - Missense	12:112453279-112453279,	PATHOGENIC	0.96131	28481359
PTPN11	9644	COSM13018,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E139D	Substitution - Missense	12:112453279-112453279,	PATHOGENIC	0.96131	23832011
PTPN11	9644	COSM13018,	central_nervous_system	glioma	p.E139D	Substitution - Missense	12:112453279-112453279,	PATHOGENIC	0.96131	28481359
PTPN11	9644	COSM13018,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E139D	Substitution - Missense	12:112453279-112453279,	PATHOGENIC	0.96131	14644997
PTPN11	9644	COSM13018,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E139D	Substitution - Missense	12:112453279-112453279,	PATHOGENIC	0.96131	27276561
PTPN11	9644	COSM13018,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E139D	Substitution - Missense	12:112453279-112453279,	PATHOGENIC	0.96131	21901340
PTPN11	9644	COSM6927188,	lung	carcinoma	p.I309M	Substitution - Missense	12:112477724-112477724,	PATHOGENIC	0.96115	28481359
PTPN11	9644	COSM1948766,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510H	Substitution - Missense	12:112489106-112489106,	PATHOGENIC	0.96084	27534895
PTPN11	9644	COSM1948766,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510H	Substitution - Missense	12:112489106-112489106,	PATHOGENIC	0.96084	27276561
PTPN11	9644	COSM1948766,	lung	carcinoma	p.Q510H	Substitution - Missense	12:112489106-112489106,	PATHOGENIC	0.96084	26317919
PTPN11	9644	COSM1948766,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510H	Substitution - Missense	12:112489106-112489106,	PATHOGENIC	0.96084	27534895
PTPN11	9644	COSM1948766,	central_nervous_system	glioma	p.Q510H	Substitution - Missense	12:112489106-112489106,	PATHOGENIC	0.96084	24695838
PTPN11	9644	COSM1358884,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.N58K	Substitution - Missense	12:112450354-112450354,	PATHOGENIC	0.96047	27276561
PTPN11	9644	COSM5575902,	stomach	carcinoma	p.L74F	Substitution - Missense	12:112450402-112450402,	PATHOGENIC	0.96043	26489445
PTPN11	9644	COSM5030959,	salivary_gland	carcinoma	p.V490I	Substitution - Missense	12:112489044-112489044,	PATHOGENIC	0.95991	26053092
PTPN11	9644	COSM6005587,	prostate	carcinoma	p.A392V	Substitution - Missense	12:112482156-112482156,	PATHOGENIC	0.95951	20579941
PTPN11	9644	COSM6919376,	central_nervous_system	glioma	p.I282V	Substitution - Missense	12:112473031-112473031,	PATHOGENIC	0.95652	28481359
PTPN11	9644	COSM5610083,	skin	malignant_melanoma	p.P561Q	Substitution - Missense	12:112502226-112502226,	PATHOGENIC	0.95112	26343386
PTPN11	9644	COSM6438173,	large_intestine	carcinoma	p.L98F	Substitution - Missense	12:112450472-112450472,	PATHOGENIC	0.95017	27756406
PTPN11	9644	COSM6919314,	large_intestine	carcinoma	p.K91N	Substitution - Missense	12:112450453-112450453,	PATHOGENIC	0.94959	28481359
PTPN11	9644	COSM327246,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.K322K	Substitution - coding silent	12:112477889-112477889,	PATHOGENIC	0.94811	22675565
PTPN11	9644	COSM48892,	lung	carcinoma	p.Y418*	Substitution - Nonsense	12:112486504-112486504,	PATHOGENIC	0.94319	18948947
PTPN11	9644	COSM6971710,	NS	malignant_melanoma	p.H443Y	Substitution - Missense	12:112486577-112486577,	PATHOGENIC	0.9428	28481359
PTPN11	9644	COSM5945279,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F285L	Substitution - Missense	12:112473040-112473040,	PATHOGENIC	0.94242	27276561
PTPN11	9644	COSM13024,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.94176	15385933
PTPN11	9644	COSM327245,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.M82T	Substitution - Missense	12:112450425-112450425,	PATHOGENIC	0.9402	22675565
PTPN11	9644	COSM1948758,	large_intestine	carcinoma	p.R351*	Substitution - Nonsense	12:112477974-112477974,	PATHOGENIC	0.93956	28481359
PTPN11	9644	COSM13029,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	27276561
PTPN11	9644	COSM13029,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	21680795
PTPN11	9644	COSM13029,	small_intestine	carcinoma	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	24797764
PTPN11	9644	COSM13029,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	12717436
PTPN11	9644	COSM13029,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	27276561
PTPN11	9644	COSM13029,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	27276561
PTPN11	9644	COSM13029,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	27288520
PTPN11	9644	COSM13029,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	21680795
PTPN11	9644	COSM13029,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71L	Substitution - Missense	12:112450393-112450393,	PATHOGENIC	0.93733	15842656
PTPN11	9644	COSM5610085,	skin	malignant_melanoma	p.S499F	Substitution - Missense	12:112489072-112489072,	PATHOGENIC	0.93004	26343386
PTPN11	9644	COSM4384771,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H444Y	Substitution - Missense	12:112486580-112486580,	PATHOGENIC	0.91832	24030381
PTPN11	9644	COSM1948765,	biliary_tract	carcinoma	p.R498W	Substitution - Missense	12:112489068-112489068,	PATHOGENIC	0.91772	29360550
PTPN11	9644	COSM327247,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.T553M	Substitution - Missense	12:112502202-112502202,	PATHOGENIC	0.91037	22675565
PTPN11	9644	COSM6918469,	urinary_tract	carcinoma	p.T397M	Substitution - Missense	12:112482171-112482171,	PATHOGENIC	0.90072	28481359
PTPN11	9644	COSM14257,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L77V	Substitution - Missense	12:112450409-112450409,	PATHOGENIC	0.89378	16358218
PTPN11	9644	COSM5610082,	skin	malignant_melanoma	p.R186Q	Substitution - Missense	12:112454595-112454595,	PATHOGENIC	0.89207	26343386
PTPN11	9644	COSM147614,	upper_aerodigestive_tract	carcinoma	p.Y197*	Substitution - Nonsense	12:112454629-112454629,	PATHOGENIC	0.87047	28581676
PTPN11	9644	COSM5610081,	skin	malignant_melanoma	p.G119G	Substitution - coding silent	12:112453219-112453219,	PATHOGENIC	0.85541	26343386
PTPN11	9644	COSM5991632,	skin	adnexal_tumour	p.R512*	Substitution - Nonsense	12:112489110-112489110,	PATHOGENIC	0.85176	27311873
PTPN11	9644	COSM6944257,	lung	carcinoma	p.L126F	Substitution - Missense	12:112453240-112453240,	PATHOGENIC	0.83451	28481359
PTPN11	9644	COSM13001,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A16A	Substitution - coding silent	12:112446309-112446309,	PATHOGENIC	0.76366	15009076
PTPN11	9644	COSM26147,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.L74M	Substitution - Missense	12:112450400-112450400,	NEUTRAL	0.22428	17972951
PTPN11	9644	COSM5020449,	soft_tissue	haemangioblastoma	p.?	Unknown	12:112482065-112482065,	NEUTRAL	0.20771	25589003
PTPN11	9644	COSM5020449,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	12:112482065-112482065,	NEUTRAL	0.20771	27534895
PTPN11	9644	COSM5020449,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	12:112482065-112482065,	NEUTRAL	0.20771	27534895
PTPN11	9644	COSM5020449,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	12:112482065-112482065,	NEUTRAL	0.20771	27534895
PTPN11	9644	COSM26981,	kidney	carcinoma	p.G427G	Substitution - coding silent	12:112486531-112486531,	NEUTRAL	0.06548	20054297
PTPN11	9644	COSM5020320,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	27534895
PTPN11	9644	COSM5020320,	soft_tissue	haemangioblastoma	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	25589003
PTPN11	9644	COSM5020320,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	27534895
PTPN11	9644	COSM5020320,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	27534895
PTPN11	9644	COSM5020320,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	27534895
PTPN11	9644	COSM5020320,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	27534895
PTPN11	9644	COSM5020320,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	27534895
PTPN11	9644	COSM5020320,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	27534895
PTPN11	9644	COSM5020320,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.H85H	Substitution - coding silent	12:112450435-112450435,	NEUTRAL	0.02829	27534895
PTPN11	9644	COSM53222,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	26341754
PTPN11	9644	COSM133828,	skin	malignant_melanoma	p.Q510L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	28870692
PTPN11	9644	COSM13100,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E69V	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27884971
PTPN11	9644	COSM6438172,	large_intestine	carcinoma	p.A75fs*14	Deletion - Frameshift	12:112450402-112450402,	Info_not_available	Info_not_available	27756406
PTPN11	9644	COSM14261,	lung	carcinoma	p.A72V	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27528220
PTPN11	9644	COSM5945274,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61F	Substitution - Missense	12:112450361-112450362,	Info_not_available	Info_not_available	27276561
PTPN11	9644	COSM13104,	central_nervous_system	glioma	p.T507K	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27245685
PTPN11	9644	COSM13104,	central_nervous_system	other	p.T507K	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27061725
PTPN11	9644	COSM6506606,	breast	carcinoma	p.Q506H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	27034166
PTPN11	9644	COSM5611360,	skin	malignant_melanoma	p.A72V, p.G464N	Substitution - Missense	12:112488453-112488454,	Info_not_available	Info_not_available	26343386
PTPN11	9644	COSM14275,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T, p.D61V, p.G503A	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	24850867
PTPN11	9644	COSM5751340,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.D61fs*4	Insertion - Frameshift	12:112450361-112450362,	Info_not_available	Info_not_available	26206799
PTPN11	9644	COSM14261,	NS	carcinoma	p.A72V	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	26182302
PTPN11	9644	COSM13991,	breast	carcinoma	p.S502L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25927147
PTPN11	9644	COSM5881430,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61V, p.P491L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25516983
PTPN11	9644	COSM5945734,	central_nervous_system	glioma	p.E76fs*?	Frameshift	Info_not_available	Info_not_available	Info_not_available	25257301
PTPN11	9644	COSM4606329,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72A, p.A72V, p.D61>IPQP, p.D61H, p.E69K, p.E76K, p.G503A, p.G60V	Complex - insertion inframe, Substitution - Missense, Substitution - coding silent	Info_not_available	Info_not_available	Info_not_available	25253770
PTPN11	9644	COSM4989846,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.A72D, p.A72T, p.E76G, p.G60V, p.S502P	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25207766
PTPN11	9644	COSM4169700,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T, p.A72V, p.D61V, p.D61Y, p.E76A, p.E76G, p.E76K, p.E76Q, p.E76V, p.G503A, p.G60R	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	25097206
PTPN11	9644	COSM53222,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	25022553
PTPN11	9644	COSM13030,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.F71K	Substitution - Missense	12:112450391-112450393,	Info_not_available	Info_not_available	12717436
PTPN11	9644	COSM13106,	NS, autonomic_ganglia, haematopoietic_and_lymphoid_tissue, large_intestine, lung	carcinoma, haematopoietic_neoplasm, malignant_melanoma, neuroblastoma	p.D61Y, p.E69K, p.E69V, p.E76G, p.E76V, p.G503V, p.N58S, p.R138Q, p.R289G, p.T507K, p.V45L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	15604238
PTPN11	9644	COSM14261,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T, p.A72V, p.E76V, p.G503A	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	15667533
PTPN11	9644	COSM14273,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V, p.G60V, p.H53Q	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	15749679
PTPN11	9644	COSM14261,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72V	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	15834506
PTPN11	9644	COSM14270,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76M	Substitution - Missense	12:112450406-112450407,	Info_not_available	Info_not_available	15928039
PTPN11	9644	COSM14276,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.D61N, p.D61V, p.G503A, p.G60R	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	15951301
PTPN11	9644	COSM13992,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T, p.E69G, p.E76G, p.E76V, p.F71K, p.G503A, p.S502L, p.S502P, p.T73I	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	16115145
PTPN11	9644	COSM14260,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.G503L	Substitution - Missense	12:112489083-112489084,	Info_not_available	Info_not_available	16358218
PTPN11	9644	COSM13099,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76G	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	16424869
PTPN11	9644	COSM14272,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.G60V, p.T507K	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	18701506
PTPN11	9644	COSM28007,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.A72T, p.Q510H	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	18925961
PTPN11	9644	COSM53222,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	20693432
PTPN11	9644	COSM53222,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	20884804
PTPN11	9644	COSM133828,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.Q510L	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	22131879
PTPN11	9644	COSM53222,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	22237106
PTPN11	9644	COSM1570293,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76K	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	23620576
PTPN11	9644	COSM53222,	lung	carcinoma	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	23907151
PTPN11	9644	COSM4170216,	haematopoietic_and_lymphoid_tissue	lymphoid_neoplasm	p.?, p.E69K, p.F71Y	Substitution - Missense, Unknown	Info_not_available	Info_not_available	Info_not_available	24067137
PTPN11	9644	COSM53222,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.?	Unknown	Info_not_available	Info_not_available	Info_not_available	24117422
PTPN11	9644	COSM1570293,	ovary	carcinoma	p.E76K	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	24220311
PTPN11	9644	COSM4169325,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm	p.E76Q, p.G503V	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	24674452
PTPN11	9644	COSM3734700,	haematopoietic_and_lymphoid_tissue	haematopoietic_neoplasm, lymphoid_neoplasm	p.D61Y, p.N58Y	Substitution - Missense	Info_not_available	Info_not_available	Info_not_available	24771269
PTPN11	9644	COSM314578,	lung	carcinoma	p.L549L	Substitution - coding silent	12:112502189-112502189,	Info_not_available	0.6603	22941188
PTPN11	9644	COSM6986873,	genital_tract, lung, skin	carcinoma, germ_cell_tumour, malignant_melanoma	p.G434fs*38, p.I479delI, p.P107F, p.R46G	Deletion - Frameshift, Deletion - In frame, Substitution - Missense	12:112488494-112488496,	Info_not_available	0.62222, Info_not_available	28481359