Gene Name	HGNC ID	COSMIC_MutID	Primary site	Primary histology	AA-Mutation	Mutation Type	Genomic Position	FATHMM prediction	FATHMM score	Literature evidence
PDHA2	8807	COSM2989186,	oesophagus	carcinoma	p.Q78E	Substitution - Missense	4:95840382-95840382,	PATHOGENIC	0.9759	24686850
PDHA2	8807	COSM5047481,	oesophagus	carcinoma	p.C92*	Substitution - Nonsense	4:95840426-95840426,	NEUTRAL	0.32807	24686850
PDHA2	8807	COSM39464,	central_nervous_system	glioma	p.E307K	Substitution - Missense	4:95841069-95841069,	NEUTRAL	0.0443	18772396