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Collapse Statistics
226 human active and 11 inactive phosphatases in total;
194 phosphatases have substrate data;
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305 protein substrates;
89 non-protein substrates;
1114 dephosphorylation interactions;
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213 KEGG pathways;
206 NCI Nature PID pathways
560 Reactome pathways;
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last update: 18 Feb, 2016

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KEGG Pathway - Fructose and mannose metabolism

Phosphatases known in this pathway

NameSynonymsUniProt ACDephosphorylate substrates:
FBP2 (QuickGO)FBPase 2O00757D-fructose 1,6-bisphosphate
PFKFB2 (QuickGO)PFK/FBPase 2O60825beta-D-fructose 2,6-bisphosphate
FBP1 (QuickGO)FBPase 1P09467D-fructose 1,6-bisphosphate
PFKFB1 (QuickGO)PFK/FBPase 1P16118beta-D-fructose 2,6-bisphosphate
MTMR1 (QuickGO)MTMR1Q13613PtdIns(3,5)P2 PtdIns(3)P
MTMR2 (QuickGO)MTMR2Q13614Ins(1,3)P2 PtdIns(3,5)P2 PtdIns(3)P
PFKFB3 (QuickGO)PFK/FBPase 3Q16875beta-D-fructose 2,6-bisphosphate
PFKFB4 (QuickGO)PFK/FBPase 4Q16877beta-D-fructose 2,6-bisphosphate
PMM1 (QuickGO)PMM 1Q92871glucose 1,6-bisphosphate
C12orf5 (QuickGO)TIGARQ9NQ88beta-D-fructose 2,6-bisphosphate D-fructose 1,6-bisphosphate
PHPT1 (QuickGO)PHPT1Q9NRX4ACL GNB1 HIST1H1C Histone H4 KCa3.1 poly(lysine) polymer
MTMR7 (QuickGO)MTMR7Q9Y216Ins(1,3)P2 PtdIns(3,5)P2 PtdIns(3)P
MTMR6 (QuickGO)MTMR6Q9Y217PtdIns(3,5)P2 PtdIns(3)P

Substrates known in this pathway

NameSynonymsUniProt ACDephosphorylated by phosphatases:
beta-D-fructose 2,6-bisphosphate2,6-di-O-phosphono--D-fructofuranose; D-Fructose 2,6-bisphosphate; FRUCTOSE-2,6-DIPHOSPHATE; beta-D-fructose 2,6-bisphosphate; FDPN/APFK/FBPase 1 PFK/FBPase 2 PFK/FBPase 3 PFK/FBPase 4 TIGAR
D-fructose 1-phosphate1-O-phosphono-D-fructose; D-Fructose 1-phosphateN/AIMP 1

Sorry, no phosphatase/substrate known in this pathway here!

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