spacer
Collapse Statistics
226 human active and 11 inactive phosphatases in total;
194 phosphatases have substrate data;
--------------------------------
305 protein substrates;
89 non-protein substrates;
1114 dephosphorylation interactions;
--------------------------------
213 KEGG pathways;
206 NCI Nature PID pathways
560 Reactome pathways;
--------------------------------
last update: 18 Feb, 2016

spacer

MTMR7

Gene Name MTMR7 (QuickGO)SynonymsMTMR7
Protein NameMyotubularin-related protein 7
Alternative name(s)
Myotubularin-related protein 7 (EC 3.1.3.-)
Ensembl Gene IDENSG00000003987EntrezGene ID9108
UniProt AC (Human)Q9Y216 (protein sequence)Enzyme ClassEC 3.1.3.- (BRENDA )
Molecular Weight75833Protein Length660
Phosphatase activityactive
Protein DomainInterPro | Pfam3D Structure * PDB | PDBe | DrugPort
* ModBase | SwissModel
Structure-based FamilyFamily 1 (CATH: 3.90.190.10)Historical ClassPTPs >> Class I Cys-based PTPs >> VH1-like or dual-specificity phosphatases (DSPs) >> Myotubularins
Localization cytoplasm (PubMed: 16787938 | Europe PMC)
Catalytic SiteCatalytic Site Atlas Target by Small MoleculesN/A
Gene ExpressionGene Expression Atlas

The Human Protein Atlas

Function and DiseaseOMIM
Protein-protein Interaction Database STRING | IntAct | MINT
Kinase Database Phospho.ELM | PhosphoSite | NetworKIN
Function (UniProt annotation)
FUNCTION: Phosphatase that acts on lipids with a phosphoinositol headgroup (Probable).
Catalytic Activity (UniProt annotation)
N/A
Protein Sequence
MEHIRTPKVE NVRLVDRVSP KKAALGTLYL TATHVIFVEN SPDPRKETWI LHSQISTIEK QATTATGCPL LIRCKNFQII QLIIPQERDC HDVYISLIRL ARPVKYEELY CFSFNPMLDK EEREQGWVLI DLSEEYTRMG LPNHYWQLSD VNRDYRVCDS YPTELYVPKS ATAHIIVGSS KFRSRRRFPV LSYYYKDNHA SICRSSQPLS GFSARCLEDE QMLQAIRKAN PGSDFVYVVD TRPKLNAMAN RAAGKGYENE DNYSNIKFQF IGIENIHVMR NSLQKMLEVC ELKSPSMSDF LWGLENSGWL RHIKAIMDAG IFIAKAVSEE GASVLVHCSD GWDRTAQVCS VASLLLDPHY RTLKGFMVLI EKDWISFGHK FNHRYGNLDG DPKEISPVID QFIECVWQLM EQFPCAFEFN ERFLIHIQHH IYSCQFGNFL CNSQKERREL KIQERTYSLW AHLWKNRADY LNPLFRADHS QTQGTLHLPT TPCNFMYKFW SGMYNRFEKG MQPRQSVTDY LMAVKEETQQ LEEELEALEE RLEKIQKVQL NCTKVKSKQS EPSKHSGFST SDNSIANTPQ DYSGNMKSFP SRSPSQGDED SALILTQDNL KSSDPDLSAN SDQESGVEDL SCRSPSGGEH APSEDSGKDR DSDEAVFLTA
ELM motif
N/A
Gene Ontology
GO:0004725protein tyrosine phosphatase activity

spacer
spacer