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Collapse Statistics
226 human active and 11 inactive phosphatases in total;
194 phosphatases have substrate data;
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305 protein substrates;
89 non-protein substrates;
1114 dephosphorylation interactions;
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213 KEGG pathways;
206 NCI Nature PID pathways
560 Reactome pathways;
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last update: 18 Feb, 2016

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NT5DC3

Gene Name NT5DC3 (QuickGO)SynonymsNT5DC3 GNN TU12B1-TY
Protein Name5'-nucleotidase domain-containing protein 3
Alternative name(s)
5'-nucleotidase domain-containing protein 3 (EC 3.1.3.-) (GRP94-neighboring nucleotidase)
Ensembl Gene IDENSG00000111696EntrezGene ID51559
UniProt AC (Human)Q86UY8 (protein sequence)Enzyme ClassEC 3.1.3.- (BRENDA )
Molecular Weight63420Protein Length548
Phosphatase activityactive
Protein DomainInterPro | Pfam3D Structure * PDB | PDBe | DrugPort
* ModBase | SwissModel
Structure-based FamilyFamily 7 (CATH: 3.40.50.1000)Historical Class5'(3')-deoxyribonucleotidase
Localization N/A
Catalytic SiteCatalytic Site Atlas Target by Small MoleculesN/A
Gene ExpressionGene Expression Atlas

The Human Protein Atlas

Function and DiseaseOMIM
Protein-protein Interaction Database STRING | IntAct | MINT
Kinase Database Phospho.ELM | PhosphoSite | NetworKIN
Function (UniProt annotation)
N/A
Catalytic Activity (UniProt annotation)
N/A
Protein Sequence
MTMAAAAVVA RGAGARAATA AALRGGCGTA ARGRPCAGPA RPLCTAPGTA PDMKRYLWER YREAKRSTEE LVPSIMSNLL NPDAIFSNNE MSLSDIEIYG FDYDYTLVFY SKHLHTLIFN AARDLLINEH RYPAEIRKYE YDPNFAIRGL HYDVQRAVLM KIDAFHYIQL GTVYRGLSVV PDEEVIEMYE GSHVPLEQMS DFYGKSSHGN TMKQFMDIFS LPEMTLLSCV NEYFLKNNID YEPVHLYKDV KDSIRDVHIK GIMYRAIEAD IEKYICYAEQ TRAVLAKLAD HGKKMFLITN SPSSFVDKGM SYIVGKDWRD LFDVVIVQAE KPNFFNDKRR PFRKMNEKGV LLWDKIHKLQ KGQIYKQGNL YEFLKLTGWR GSRVLYFGDH IYSDLADLTL KHGWRTGAII PELRSELKIM NTEQYIQTMT WLQTLTGLLE QMQVHRDAES QLVLQEWKKE RKEMREMTKS FFNAQFGSLF RTDQNPTYFL RRLSRFADIY MASLSCLLNY DVSHTFYPRR TPLQHELPAW SERPPTFGTP LLQEAQAK
ELM motif
N/A
Gene Ontology
GO:0016787hydrolase activity
GO:0046872metal ion binding

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