Name Function Pathway ID in source database Pathway name Pathway source database FBP2 Phosphatase REACT_1520 Gluconeogenesis Reactome Pathway PPAP2A Phosphatase REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway PPAP2B Phosphatase REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway CTDSP2 Phosphatase REACT_18273 XBP1(S) activates chaperone genes Reactome Pathway IMPA2 Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway PPEF1 Phosphatase REACT_163919 Inactivation, recovery and regulation of the phototransduction cascade Reactome Pathway SYNJ2 Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway INPP4B Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway INPP4B Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway INPP4B Phosphatase REACT_120756 Synthesis of PIPs at the early endosome membrane Reactome Pathway INPPL1 Phosphatase REACT_23891 Interleukin receptor SHC signaling Reactome Pathway INPPL1 Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway INPPL1 Phosphatase REACT_23891 Interleukin receptor SHC signaling Reactome Pathway INPPL1 Phosphatase REACT_150312 Synthesis of IP3 and IP4 in the cytosol Reactome Pathway SYNJ1 Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway SYNJ1 Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway SYNJ1 Phosphatase REACT_150312 Synthesis of IP3 and IP4 in the cytosol Reactome Pathway PPAP2C Phosphatase REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway PHLPP1 Phosphatase REACT_12447 Negative regulation of the PI3K/AKT network Reactome Pathway PFKFB2 Phosphatase REACT_1383 Glycolysis Reactome Pathway RNGTT Phosphatase REACT_1470 mRNA Capping Reactome Pathway RNGTT Phosphatase REACT_975 RNA Pol II CTD phosphorylation and interaction with CE Reactome Pathway RNGTT Phosphatase REACT_6237 RNA Pol II CTD phosphorylation and interaction with CE Reactome Pathway DNAJC6 Phosphatase REACT_19287 Lysosome Vesicle Biogenesis Reactome Pathway DNAJC6 Phosphatase REACT_19400 Golgi Associated Vesicle Biogenesis Reactome Pathway PPM1B Phosphatase REACT_115831 ISG15 antiviral mechanism Reactome Pathway EPM2A Phosphatase REACT_169208 Glycogen synthesis Reactome Pathway EPM2A Phosphatase REACT_200783 Myoclonic epilepsy of Lafora Reactome Pathway CTDNEP1 Phosphatase REACT_200828 Depolymerisation of the Nuclear Lamina Reactome Pathway BPNT1 Phosphatase REACT_6913 Cytosolic sulfonation of small molecules Reactome Pathway PTPRC Phosphatase REACT_12582 Phosphorylation of CD3 and TCR zeta chains Reactome Pathway PTPRC Phosphatase REACT_19200 Other semaphorin interactions Reactome Pathway FBP1 Phosphatase REACT_1520 Gluconeogenesis Reactome Pathway ACP5 Phosphatase REACT_11070 Vitamin B2 (riboflavin) metabolism Reactome Pathway PGAM2 Phosphatase REACT_1383 Glycolysis Reactome Pathway PGAM2 Phosphatase REACT_1520 Gluconeogenesis Reactome Pathway PFKFB1 Phosphatase REACT_1383 Glycolysis Reactome Pathway PFKFB1 Phosphatase REACT_1525 PKA-mediated phosphorylation of key metabolic factors Reactome Pathway PFKFB1 Phosphatase REACT_1520 Gluconeogenesis Reactome Pathway PFKFB1 Phosphatase REACT_705 PP2A-mediated dephosphorylation of key metabolic factors Reactome Pathway PPP3CB Phosphatase REACT_163834 FCERI mediated Ca+2 mobilization Reactome Pathway PPP3CB Phosphatase REACT_15334 DARPP-32 events Reactome Pathway PPP3CB Phosphatase REACT_172761 Ca2+ pathway Reactome Pathway PTPN2 Phosphatase REACT_24980 Regulation of IFNG signaling Reactome Pathway PTPN1 Phosphatase REACT_25216 Regulation of IFNA signaling Reactome Pathway PTPN1 Phosphatase REACT_15523 Integrin alphaIIb beta3 signaling Reactome Pathway PTPN1 Phosphatase REACT_111133 Growth hormone receptor signaling Reactome Pathway PTPN1 Phosphatase REACT_24980 Regulation of IFNG signaling Reactome Pathway PTPRA Phosphatase REACT_18334 NCAM signaling for neurite out-growth Reactome Pathway PGAM1 Phosphatase REACT_1383 Glycolysis Reactome Pathway PGAM1 Phosphatase REACT_1520 Gluconeogenesis Reactome Pathway NT5E Phosphatase REACT_1023 Pyrimidine catabolism Reactome Pathway NT5E Phosphatase REACT_2086 Purine catabolism Reactome Pathway IMPA1 Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway PTPN6 Phosphatase REACT_23891 Interleukin receptor SHC signaling Reactome Pathway PTPN6 Phosphatase REACT_25216 Regulation of IFNA signaling Reactome Pathway PTPN6 Phosphatase REACT_111225 Regulation of KIT signaling Reactome Pathway PTPN6 Phosphatase REACT_111133 Growth hormone receptor signaling Reactome Pathway PTPN6 Phosphatase REACT_23879 Platelet sensitization by LDL Reactome Pathway PTPN6 Phosphatase REACT_25162 Interferon alpha/beta signaling Reactome Pathway PTPN6 Phosphatase REACT_19344 Costimulation by the CD28 family Reactome Pathway PTPN6 Phosphatase REACT_24980 Regulation of IFNG signaling Reactome Pathway PTPN6 Phosphatase REACT_23916 Signal regulatory protein (SIRP) family interactions Reactome Pathway PTPN6 Phosphatase REACT_23891 Interleukin receptor SHC signaling Reactome Pathway PTPN6 Phosphatase REACT_19324 PD-1 signaling Reactome Pathway PTPN6 Phosphatase REACT_23837 Interleukin-3, 5 and GM-CSF signaling Reactome Pathway PTPN6 Phosphatase REACT_12519 PECAM1 interactions Reactome Pathway PTPN6 Phosphatase REACT_25078 Interferon gamma signaling Reactome Pathway CDC25A Phosphatase REACT_2101 Cyclin B2 mediated events Reactome Pathway CDC25A Phosphatase REACT_2160 p53-Independent DNA Damage Response Reactome Pathway CDC25A Phosphatase REACT_1006 Polo-like kinase mediated events Reactome Pathway CDC25A Phosphatase REACT_111214 G0 and Early G1 Reactome Pathway CDC25A Phosphatase REACT_6769 Activation of ATR in response to replication stress Reactome Pathway CDC25A Phosphatase REACT_1574 Cyclin E associated events during G1/S transition Reactome Pathway CDC25A Phosphatase REACT_683 G1/S-Specific Transcription Reactome Pathway CDC25A Phosphatase REACT_1857 Cyclin A/B1 associated events during G2/M transition Reactome Pathway CDC25A Phosphatase REACT_471 E2F mediated regulation of DNA replication Reactome Pathway CDC25A Phosphatase REACT_1614 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Reactome Pathway CDC25A Phosphatase REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Reactome Pathway CDC25A Phosphatase REACT_1321 E2F-enabled inhibition of pre-replication complex formation Reactome Pathway CDC25B Phosphatase REACT_2101 Cyclin B2 mediated events Reactome Pathway CDC25B Phosphatase REACT_1857 Cyclin A/B1 associated events during G2/M transition Reactome Pathway CDC25B Phosphatase REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Reactome Pathway CDC25C Phosphatase REACT_2101 Cyclin B2 mediated events Reactome Pathway CDC25C Phosphatase REACT_1006 Polo-like kinase mediated events Reactome Pathway CDC25C Phosphatase REACT_407 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Reactome Pathway CDC25C Phosphatase REACT_6769 Activation of ATR in response to replication stress Reactome Pathway CDC25C Phosphatase REACT_1857 Cyclin A/B1 associated events during G2/M transition Reactome Pathway INPP5B Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway INPP5B Phosphatase REACT_11051 Rho GTPase cycle Reactome Pathway INPP5B Phosphatase REACT_150312 Synthesis of IP3 and IP4 in the cytosol Reactome Pathway G6PC Phosphatase REACT_212 Glucose transport Reactome Pathway PPM1A Phosphatase REACT_21285 Regulation of AMPK activity via LKB1 Reactome Pathway PPM1A Phosphatase REACT_121111 Downregulation of SMAD2/3:SMAD4 transcriptional activity Reactome Pathway PPP1CC Phosphatase REACT_120727 Downregulation of TGF-beta receptor signaling Reactome Pathway PPP1CC Phosphatase REACT_494 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Reactome Pathway PPP1CC Phosphatase REACT_150425 Resolution of Sister Chromatid Cohesion Reactome Pathway PPP1CC Phosphatase REACT_150471 Separation of Sister Chromatids Reactome Pathway PPP1CC Phosphatase REACT_682 Mitotic Prometaphase Reactome Pathway PPP3CC Phosphatase REACT_549 Activation of BAD and translocation to mitochondria Reactome Pathway PPP3CC Phosphatase REACT_15334 DARPP-32 events Reactome Pathway INPP1 Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway NT5C2 Phosphatase REACT_121388 Abacavir metabolism Reactome Pathway NT5C2 Phosphatase REACT_2086 Purine catabolism Reactome Pathway DUSP3 Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway DUSP3 Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway TPTE Phosphatase REACT_120836 Synthesis of PIPs at the Golgi membrane Reactome Pathway PTEN Phosphatase REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway PTEN Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway PTEN Phosphatase REACT_12447 Negative regulation of the PI3K/AKT network Reactome Pathway PTEN Phosphatase REACT_12555 Downstream TCR signaling Reactome Pathway PTEN Phosphatase REACT_75829 PIP3 activates AKT signaling Reactome Pathway PTEN Phosphatase REACT_150312 Synthesis of IP3 and IP4 in the cytosol Reactome Pathway PPP1CA Phosphatase REACT_120727 Downregulation of TGF-beta receptor signaling Reactome Pathway PPP1CA Phosphatase REACT_494 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Reactome Pathway PPP1CA Phosphatase REACT_15334 DARPP-32 events Reactome Pathway PPP1CB Phosphatase REACT_120727 Downregulation of TGF-beta receptor signaling Reactome Pathway PPP1CB Phosphatase REACT_160315 Regulation of PLK1 Activity at G2/M Transition Reactome Pathway PPP1CB Phosphatase REACT_494 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Reactome Pathway PPP2CB Phosphatase REACT_11065 Beta-catenin phosphorylation cascade Reactome Pathway PPP2CB Phosphatase REACT_150425 Resolution of Sister Chromatid Cohesion Reactome Pathway PPP2CB Phosphatase REACT_1383 Glycolysis Reactome Pathway PPP2CB Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway PPP2CB Phosphatase REACT_19405 CTLA4 inhibitory signaling Reactome Pathway PPP2CB Phosphatase REACT_23879 Platelet sensitization by LDL Reactome Pathway PPP2CB Phosphatase REACT_821 Cyclin D associated events in G1 Reactome Pathway PPP2CB Phosphatase REACT_12599 ERK/MAPK targets Reactome Pathway PPP2CB Phosphatase REACT_200610 disassembly of the destruction complex and recruitment of AXIN to the membrane Reactome Pathway PPP2CB Phosphatase REACT_329 Inhibition of replication initiation of damaged DNA by RB1/E2F1 Reactome Pathway PPP2CB Phosphatase REACT_150182 MASTL Facilitates Mitotic Progression Reactome Pathway PPP2CB Phosphatase REACT_1857 Cyclin A/B1 associated events during G2/M transition Reactome Pathway PPP2CB Phosphatase REACT_12599 ERK/MAPK targets Reactome Pathway PPP2CB Phosphatase REACT_11063 Degradation of beta-catenin by the destruction complex Reactome Pathway PPP2CB Phosphatase REACT_111080 Spry regulation of FGF signaling Reactome Pathway PPP2CB Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway PPP2CB Phosphatase REACT_1505 Integration of energy metabolism Reactome Pathway PPP2CB Phosphatase REACT_150471 Separation of Sister Chromatids Reactome Pathway PPP2CB Phosphatase REACT_705 PP2A-mediated dephosphorylation of key metabolic factors Reactome Pathway PPP2CB Phosphatase REACT_15334 DARPP-32 events Reactome Pathway PPP2CB Phosphatase REACT_682 Mitotic Prometaphase Reactome Pathway PPP2CA Phosphatase REACT_11065 Beta-catenin phosphorylation cascade Reactome Pathway PPP2CA Phosphatase REACT_150425 Resolution of Sister Chromatid Cohesion Reactome Pathway PPP2CA Phosphatase REACT_1383 Glycolysis Reactome Pathway PPP2CA Phosphatase REACT_160242 Initiation of Nuclear Envelope Reformation Reactome Pathway PPP2CA Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway PPP2CA Phosphatase REACT_19405 CTLA4 inhibitory signaling Reactome Pathway PPP2CA Phosphatase REACT_23879 Platelet sensitization by LDL Reactome Pathway PPP2CA Phosphatase REACT_821 Cyclin D associated events in G1 Reactome Pathway PPP2CA Phosphatase REACT_12599 ERK/MAPK targets Reactome Pathway PPP2CA Phosphatase REACT_200610 disassembly of the destruction complex and recruitment of AXIN to the membrane Reactome Pathway PPP2CA Phosphatase REACT_329 Inhibition of replication initiation of damaged DNA by RB1/E2F1 Reactome Pathway PPP2CA Phosphatase REACT_150182 MASTL Facilitates Mitotic Progression Reactome Pathway PPP2CA Phosphatase REACT_1857 Cyclin A/B1 associated events during G2/M transition Reactome Pathway PPP2CA Phosphatase REACT_12599 ERK/MAPK targets Reactome Pathway PPP2CA Phosphatase REACT_11063 Degradation of beta-catenin by the destruction complex Reactome Pathway PPP2CA Phosphatase REACT_111080 Spry regulation of FGF signaling Reactome Pathway PPP2CA Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway PPP2CA Phosphatase REACT_1505 Integration of energy metabolism Reactome Pathway PPP2CA Phosphatase REACT_150471 Separation of Sister Chromatids Reactome Pathway PPP2CA Phosphatase REACT_75822 Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Reactome Pathway PPP2CA Phosphatase REACT_705 PP2A-mediated dephosphorylation of key metabolic factors Reactome Pathway PPP2CA Phosphatase REACT_15334 DARPP-32 events Reactome Pathway PPP2CA Phosphatase REACT_682 Mitotic Prometaphase Reactome Pathway PSPH Phosphatase REACT_115789 Serine biosynthesis Reactome Pathway OCRL Phosphatase REACT_19400 Golgi Associated Vesicle Biogenesis Reactome Pathway OCRL Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway OCRL Phosphatase REACT_11051 Rho GTPase cycle Reactome Pathway OCRL Phosphatase REACT_120836 Synthesis of PIPs at the Golgi membrane Reactome Pathway OCRL Phosphatase REACT_150312 Synthesis of IP3 and IP4 in the cytosol Reactome Pathway PTPN11 Phosphatase REACT_25216 Regulation of IFNA signaling Reactome Pathway PTPN11 Phosphatase REACT_17025 Downstream signal transduction Reactome Pathway PTPN11 Phosphatase REACT_169118 Signaling by Leptin Reactome Pathway PTPN11 Phosphatase REACT_111184 Negative regulation of FGFR signaling Reactome Pathway PTPN11 Phosphatase REACT_21247 FRS2-mediated cascade Reactome Pathway PTPN11 Phosphatase REACT_111080 Spry regulation of FGF signaling Reactome Pathway PTPN11 Phosphatase REACT_19324 PD-1 signaling Reactome Pathway PTPN11 Phosphatase REACT_12621 Tie2 Signaling Reactome Pathway PTPN11 Phosphatase REACT_75829 PIP3 activates AKT signaling Reactome Pathway PTPN11 Phosphatase REACT_22384 Netrin mediated repulsion signals Reactome Pathway PTPN11 Phosphatase REACT_12519 PECAM1 interactions Reactome Pathway PTPN11 Phosphatase REACT_976 PI3K Cascade Reactome Pathway PTPN11 Phosphatase REACT_19405 CTLA4 inhibitory signaling Reactome Pathway PTPN11 Phosphatase REACT_23879 Platelet sensitization by LDL Reactome Pathway PTPN11 Phosphatase REACT_111040 Signaling by SCF-KIT Reactome Pathway PTPN11 Phosphatase REACT_115697 Prolactin receptor signaling Reactome Pathway PTPN11 Phosphatase REACT_25162 Interferon alpha/beta signaling Reactome Pathway PTPN11 Phosphatase REACT_19344 Costimulation by the CD28 family Reactome Pathway PTPN11 Phosphatase REACT_24980 Regulation of IFNG signaling Reactome Pathway PTPN11 Phosphatase REACT_12578 GAB1 signalosome Reactome Pathway PTPN11 Phosphatase REACT_25148 Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon Reactome Pathway PTPN11 Phosphatase REACT_23916 Signal regulatory protein (SIRP) family interactions Reactome Pathway PTPN11 Phosphatase REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway PTPN11 Phosphatase REACT_976 PI3K Cascade Reactome Pathway PTPN11 Phosphatase REACT_23837 Interleukin-3, 5 and GM-CSF signaling Reactome Pathway PTPN11 Phosphatase REACT_27307 Interleukin-6 signaling Reactome Pathway PTPN11 Phosphatase REACT_21270 PI-3K cascade Reactome Pathway PPP3CA Phosphatase REACT_163834 FCERI mediated Ca+2 mobilization Reactome Pathway PPP3CA Phosphatase REACT_15334 DARPP-32 events Reactome Pathway PPP3CA Phosphatase REACT_172761 Ca2+ pathway Reactome Pathway DUSP4 Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway DUSP4 Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway PTPRS Phosphatase REACT_163906 ECM proteoglycans Reactome Pathway MTM1 Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway MTM1 Phosphatase REACT_120756 Synthesis of PIPs at the early endosome membrane Reactome Pathway MTM1 Phosphatase REACT_120918 Synthesis of PIPs at the late endosome membrane Reactome Pathway MTMR1 Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway MTMR2 Phosphatase REACT_120756 Synthesis of PIPs at the early endosome membrane Reactome Pathway MTMR2 Phosphatase REACT_120918 Synthesis of PIPs at the late endosome membrane Reactome Pathway MTMR3 Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway INPP5A Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway LPIN1 Phosphatase REACT_120919 Synthesis of PE Reactome Pathway LPIN1 Phosphatase REACT_200828 Depolymerisation of the Nuclear Lamina Reactome Pathway LPIN1 Phosphatase REACT_121238 Synthesis of PC Reactome Pathway LPIN1 Phosphatase REACT_1190 Triglyceride Biosynthesis Reactome Pathway INPP5J Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway INPP5J Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway INPP5J Phosphatase REACT_150312 Synthesis of IP3 and IP4 in the cytosol Reactome Pathway DUSP6 Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway DUSP6 Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway DUSP7 Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway DUSP7 Phosphatase REACT_12436 ERKs are inactivated Reactome Pathway PFKFB3 Phosphatase REACT_1383 Glycolysis Reactome Pathway PFKFB4 Phosphatase REACT_1383 Glycolysis Reactome Pathway PPM1L Phosphatase REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway PPAPDC1A Phosphatase REACT_160158 Role of phospholipids in phagocytosis Reactome Pathway TPTE2 Phosphatase REACT_120836 Synthesis of PIPs at the Golgi membrane Reactome Pathway PHLPP2 Phosphatase REACT_12447 Negative regulation of the PI3K/AKT network Reactome Pathway SGPP2 Phosphatase REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway MTMR14 Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway PPAPDC1B Phosphatase REACT_160158 Role of phospholipids in phagocytosis Reactome Pathway NANP Phosphatase REACT_200874 Sialic acid metabolism Reactome Pathway NT5C Phosphatase REACT_1023 Pyrimidine catabolism Reactome Pathway NT5C Phosphatase REACT_2086 Purine catabolism Reactome Pathway PHOSPHO1 Phosphatase REACT_120919 Synthesis of PE Reactome Pathway PHOSPHO1 Phosphatase REACT_121238 Synthesis of PC Reactome Pathway PTPMT1 Phosphatase REACT_121280 Synthesis of PG Reactome Pathway LPIN2 Phosphatase REACT_120919 Synthesis of PE Reactome Pathway LPIN2 Phosphatase REACT_200828 Depolymerisation of the Nuclear Lamina Reactome Pathway LPIN2 Phosphatase REACT_121238 Synthesis of PC Reactome Pathway LPIN2 Phosphatase REACT_1190 Triglyceride Biosynthesis Reactome Pathway FIG4 Phosphatase REACT_120756 Synthesis of PIPs at the early endosome membrane Reactome Pathway FIG4 Phosphatase REACT_120918 Synthesis of PIPs at the late endosome membrane Reactome Pathway FIG4 Phosphatase REACT_120836 Synthesis of PIPs at the Golgi membrane Reactome Pathway PTPRU Phosphatase REACT_111040 Signaling by SCF-KIT Reactome Pathway INPP5D Phosphatase REACT_23891 Interleukin receptor SHC signaling Reactome Pathway INPP5D Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway INPP5D Phosphatase REACT_23891 Interleukin receptor SHC signaling Reactome Pathway INPP5D Phosphatase REACT_12555 Downstream TCR signaling Reactome Pathway INPP5D Phosphatase REACT_12519 PECAM1 interactions Reactome Pathway INPP5D Phosphatase REACT_150312 Synthesis of IP3 and IP4 in the cytosol Reactome Pathway NT5C1B Phosphatase REACT_2086 Purine catabolism Reactome Pathway INPP4A Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway INPP4A Phosphatase REACT_150352 Synthesis of IP2, IP, and Ins in the cytosol Reactome Pathway INPP4A Phosphatase REACT_120756 Synthesis of PIPs at the early endosome membrane Reactome Pathway LPIN3 Phosphatase REACT_120919 Synthesis of PE Reactome Pathway LPIN3 Phosphatase REACT_200828 Depolymerisation of the Nuclear Lamina Reactome Pathway LPIN3 Phosphatase REACT_121238 Synthesis of PC Reactome Pathway LPIN3 Phosphatase REACT_1190 Triglyceride Biosynthesis Reactome Pathway INPP5K Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway G6PC3 Phosphatase REACT_212 Glucose transport Reactome Pathway SGPP1 Phosphatase REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway NT5C1A Phosphatase REACT_1023 Pyrimidine catabolism Reactome Pathway NT5C1A Phosphatase REACT_2086 Purine catabolism Reactome Pathway NT5M Phosphatase REACT_1023 Pyrimidine catabolism Reactome Pathway G6PC2 Phosphatase REACT_212 Glucose transport Reactome Pathway INPP5E Phosphatase REACT_120836 Synthesis of PIPs at the Golgi membrane Reactome Pathway SACM1L Phosphatase REACT_121168 Synthesis of PIPs at the ER membrane Reactome Pathway SACM1L Phosphatase REACT_120836 Synthesis of PIPs at the Golgi membrane Reactome Pathway MTMR4 Phosphatase REACT_120727 Downregulation of TGF-beta receptor signaling Reactome Pathway MTMR4 Phosphatase REACT_120756 Synthesis of PIPs at the early endosome membrane Reactome Pathway MTMR4 Phosphatase REACT_120918 Synthesis of PIPs at the late endosome membrane Reactome Pathway PDP1 Phosphatase REACT_12528 Regulation of pyruvate dehydrogenase (PDH) complex Reactome Pathway PDP2 Phosphatase REACT_12528 Regulation of pyruvate dehydrogenase (PDH) complex Reactome Pathway VPS29 Phosphatase REACT_163710 WNT ligand biogenesis and trafficking Reactome Pathway ENOPH1 Phosphatase REACT_75881 Methionine salvage pathway Reactome Pathway CDC14A Phosphatase REACT_6867 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Reactome Pathway MINPP1 Phosphatase REACT_150253 Synthesis of IPs in the ER lumen Reactome Pathway MTMR7 Phosphatase REACT_120918 Synthesis of PIPs at the late endosome membrane Reactome Pathway MTMR6 Phosphatase REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway CTDP1 Phosphatase REACT_22107 RNA Polymerase II Pre-transcription Events Reactome Pathway CTDP1 Phosphatase REACT_6143 Pausing and recovery of Tat-mediated HIV elongation Reactome Pathway CTDP1 Phosphatase REACT_22201 Formation of HIV elongation complex in the absence of HIV Tat Reactome Pathway CTDP1 Phosphatase REACT_6344 Tat-mediated HIV elongation arrest and recovery Reactome Pathway CTDP1 Phosphatase REACT_6261 Abortive elongation of HIV-1 transcript in the absence of Tat Reactome Pathway CTDP1 Phosphatase REACT_6162 Tat-mediated elongation of the HIV-1 transcript Reactome Pathway CTDP1 Phosphatase REACT_846 Formation of the Early Elongation Complex Reactome Pathway CTDP1 Phosphatase REACT_6259 HIV elongation arrest and recovery Reactome Pathway CTDP1 Phosphatase REACT_1845 Formation of RNA Pol II elongation complex Reactome Pathway CTDP1 Phosphatase REACT_6244 Pausing and recovery of HIV elongation Reactome Pathway CTDP1 Phosphatase REACT_833 RNA Polymerase II Transcription Elongation Reactome Pathway CTDP1 Phosphatase REACT_6346 Formation of HIV-1 elongation complex containing HIV-1 Tat Reactome Pathway CTDP1 Phosphatase REACT_6319 Formation of the HIV-1 Early Elongation Complex Reactome Pathway PMM1 Phosphatase REACT_22423 Synthesis of GDP-mannose Reactome Pathway EPHX2 Phosphatase REACT_150417 Synthesis of epoxy (EET) and dihydroxyeicosatrienoic acids (DHET) Reactome Pathway WASL protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway WASL protein substrate REACT_12541 NOSTRIN mediated eNOS trafficking Reactome Pathway WASL protein substrate REACT_23832 Nephrin interactions Reactome Pathway WASL protein substrate REACT_22351 DCC mediated attractive signaling Reactome Pathway DNM1L protein substrate REACT_995 Apoptotic execution phase Reactome Pathway CHEK1 protein substrate REACT_897 G2/M DNA damage checkpoint Reactome Pathway CHEK1 protein substrate REACT_407 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Reactome Pathway CHEK1 protein substrate REACT_6769 Activation of ATR in response to replication stress Reactome Pathway CHEK1 protein substrate REACT_1614 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Reactome Pathway CHEK1 protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway IKBKB protein substrate REACT_24918 IRAK1 recruits IKK complex Reactome Pathway IKBKB protein substrate REACT_25374 IKK complex recruitment mediated by RIP1 Reactome Pathway IKBKB protein substrate REACT_21281 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Reactome Pathway IKBKB protein substrate REACT_13415 p75NTR recruits signalling complexes Reactome Pathway IKBKB protein substrate REACT_118656 Activation of NF-kappaB in B cells Reactome Pathway IKBKB protein substrate REACT_25039 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Reactome Pathway IKBKB protein substrate REACT_24969 TRAF6 mediated NF-kB activation Reactome Pathway IKBKB protein substrate REACT_22442 Interleukin-1 signaling Reactome Pathway IKBKB protein substrate REACT_118563 RIP-mediated NFkB activation via ZBP1 Reactome Pathway IKBKB protein substrate REACT_25354 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Reactome Pathway IKBKB protein substrate REACT_12555 Downstream TCR signaling Reactome Pathway IKBKB protein substrate REACT_163994 FCERI mediated NF-kB activation Reactome Pathway IKBKB protein substrate REACT_24918 IRAK1 recruits IKK complex Reactome Pathway IKBKB protein substrate REACT_13696 NF-kB is activated and signals survival Reactome Pathway IKBKB protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway AURKA protein substrate REACT_160315 Regulation of PLK1 Activity at G2/M Transition Reactome Pathway AURKA protein substrate REACT_6761 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Reactome Pathway CHUK protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway CHUK protein substrate REACT_24918 IRAK1 recruits IKK complex Reactome Pathway CHUK protein substrate REACT_25374 IKK complex recruitment mediated by RIP1 Reactome Pathway CHUK protein substrate REACT_21281 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Reactome Pathway CHUK protein substrate REACT_118656 Activation of NF-kappaB in B cells Reactome Pathway CHUK protein substrate REACT_25039 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Reactome Pathway CHUK protein substrate REACT_24969 TRAF6 mediated NF-kB activation Reactome Pathway CHUK protein substrate REACT_22442 Interleukin-1 signaling Reactome Pathway CHUK protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway CHUK protein substrate REACT_118563 RIP-mediated NFkB activation via ZBP1 Reactome Pathway CHUK protein substrate REACT_25354 IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation Reactome Pathway CHUK protein substrate REACT_12555 Downstream TCR signaling Reactome Pathway CHUK protein substrate REACT_163994 FCERI mediated NF-kB activation Reactome Pathway CHUK protein substrate REACT_24918 IRAK1 recruits IKK complex Reactome Pathway CHUK protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway AXIN1 protein substrate REACT_200610 disassembly of the destruction complex and recruitment of AXIN to the membrane Reactome Pathway AXIN1 protein substrate REACT_200777 TCF dependent signaling in response to WNT Reactome Pathway AXIN1 protein substrate REACT_11063 Degradation of beta-catenin by the destruction complex Reactome Pathway AXIN1 protein substrate REACT_11065 Beta-catenin phosphorylation cascade Reactome Pathway AXIN1 protein substrate REACT_200766 degradation of AXIN Reactome Pathway HDAC3 protein substrate REACT_27161 Transcriptional regulation of white adipocyte differentiation Reactome Pathway HDAC3 protein substrate REACT_160254 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome Pathway HDAC3 protein substrate REACT_116145 PPARA activates gene expression Reactome Pathway HDAC3 protein substrate REACT_118789 REV-ERBA represses gene expression Reactome Pathway HDAC3 protein substrate REACT_118780 NOTCH1 Intracellular Domain Regulates Transcription Reactome Pathway HDAC3 protein substrate REACT_200608 Transcriptional activation of mitochondrial biogenesis Reactome Pathway HDAC3 protein substrate REACT_19241 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Reactome Pathway HDAC3 protein substrate REACT_111118 BMAL1:CLOCK,NPAS2 activates circadian gene expression Reactome Pathway HDAC3 protein substrate REACT_13695 p75NTR negatively regulates cell cycle via SC1 Reactome Pathway HDAC3 protein substrate REACT_24941 Circadian Clock Reactome Pathway HDAC3 protein substrate REACT_118659 RORA activates circadian gene expression Reactome Pathway HDAC3 protein substrate REACT_160243 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome Pathway KCNN4 protein substrate REACT_75896 Ca2+ activated K+ channels Reactome Pathway MAP3K7 protein substrate REACT_25351 TRAF6 mediated induction of TAK1 complex Reactome Pathway MAP3K7 protein substrate REACT_25018 IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation Reactome Pathway MAP3K7 protein substrate REACT_21368 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Reactome Pathway MAP3K7 protein substrate REACT_21281 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Reactome Pathway MAP3K7 protein substrate REACT_25380 IRAK2 mediated activation of TAK1 complex Reactome Pathway MAP3K7 protein substrate REACT_118656 Activation of NF-kappaB in B cells Reactome Pathway MAP3K7 protein substrate REACT_22442 Interleukin-1 signaling Reactome Pathway MAP3K7 protein substrate REACT_25380 IRAK2 mediated activation of TAK1 complex Reactome Pathway MAP3K7 protein substrate REACT_12555 Downstream TCR signaling Reactome Pathway MAP3K7 protein substrate REACT_163994 FCERI mediated NF-kB activation Reactome Pathway MAP3K7 protein substrate REACT_21399 activated TAK1 mediates p38 MAPK activation Reactome Pathway MAP3K7 protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway MAP3K7 protein substrate REACT_172761 Ca2+ pathway Reactome Pathway LAT protein substrate REACT_1695 GPVI-mediated activation cascade Reactome Pathway LAT protein substrate REACT_12623 Generation of second messenger molecules Reactome Pathway PSTPIP1 protein substrate REACT_75808 The NLRP3 inflammasome Reactome Pathway SPRY1 protein substrate REACT_12484 EGFR downregulation Reactome Pathway JAK2 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway JAK2 protein substrate REACT_169118 Signaling by Leptin Reactome Pathway JAK2 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway JAK2 protein substrate REACT_24970 Factors involved in megakaryocyte development and platelet production Reactome Pathway JAK2 protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway JAK2 protein substrate REACT_23837 Interleukin-3, 5 and GM-CSF signaling Reactome Pathway JAK2 protein substrate REACT_27307 Interleukin-6 signaling Reactome Pathway JAK2 protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway JAK2 protein substrate REACT_115697 Prolactin receptor signaling Reactome Pathway JAK2 protein substrate REACT_25078 Interferon gamma signaling Reactome Pathway JAK2 protein substrate REACT_24980 Regulation of IFNG signaling Reactome Pathway CTNND1 protein substrate REACT_19195 Adherens junctions interactions Reactome Pathway NCOR1 protein substrate REACT_27161 Transcriptional regulation of white adipocyte differentiation Reactome Pathway NCOR1 protein substrate REACT_116145 PPARA activates gene expression Reactome Pathway NCOR1 protein substrate REACT_118780 NOTCH1 Intracellular Domain Regulates Transcription Reactome Pathway NCOR1 protein substrate REACT_116022 Nuclear signaling by ERBB4 Reactome Pathway NCOR1 protein substrate REACT_200608 Transcriptional activation of mitochondrial biogenesis Reactome Pathway NCOR1 protein substrate REACT_19241 Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) Reactome Pathway NCOR1 protein substrate REACT_160254 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome Pathway NCOR1 protein substrate REACT_118789 REV-ERBA represses gene expression Reactome Pathway NCOR1 protein substrate REACT_111118 BMAL1:CLOCK,NPAS2 activates circadian gene expression Reactome Pathway NCOR1 protein substrate REACT_160243 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome Pathway NCOR1 protein substrate REACT_118659 RORA activates circadian gene expression Reactome Pathway NCOR1 protein substrate REACT_121111 Downregulation of SMAD2/3:SMAD4 transcriptional activity Reactome Pathway NCOR1 protein substrate REACT_24941 Circadian Clock Reactome Pathway STAM2 protein substrate REACT_12484 EGFR downregulation Reactome Pathway STAM2 protein substrate REACT_27258 Endosomal Sorting Complex Required For Transport (ESCRT) Reactome Pathway CHEK2 protein substrate REACT_897 G2/M DNA damage checkpoint Reactome Pathway CHEK2 protein substrate REACT_1614 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Reactome Pathway ABL1 protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway ABL1 protein substrate REACT_24970 Factors involved in megakaryocyte development and platelet production Reactome Pathway ABL1 protein substrate REACT_21402 CDO in myogenesis Reactome Pathway ABL1 protein substrate REACT_19230 Role of Abl in Robo-Slit signaling Reactome Pathway EGFR protein substrate REACT_12579 SHC1 events in EGFR signaling Reactome Pathway EGFR protein substrate REACT_115720 PLCG1 events in ERBB2 signaling Reactome Pathway EGFR protein substrate REACT_9417 Signaling by EGFR Reactome Pathway EGFR protein substrate REACT_12484 EGFR downregulation Reactome Pathway EGFR protein substrate REACT_12478 EGFR interacts with phospholipase C-gamma Reactome Pathway EGFR protein substrate REACT_115596 Signaling by ERBB4 Reactome Pathway EGFR protein substrate REACT_12606 GRB2 events in EGFR signaling Reactome Pathway EGFR protein substrate REACT_115854 GRB2 events in ERBB2 signaling Reactome Pathway EGFR protein substrate REACT_116008 PI3K events in ERBB2 signaling Reactome Pathway EGFR protein substrate REACT_12578 GAB1 signalosome Reactome Pathway EGFR protein substrate REACT_22272 Signal transduction by L1 Reactome Pathway EGFR protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway EGFR protein substrate REACT_121096 EGFR Transactivation by Gastrin Reactome Pathway EGFR protein substrate REACT_115852 Signaling by constitutively active EGFR Reactome Pathway EGFR protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway EGFR protein substrate REACT_115993 SHC1 events in ERBB2 signaling Reactome Pathway EGFR protein substrate REACT_115755 Signaling by ERBB2 Reactome Pathway MYC protein substrate REACT_160254 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome Pathway MYC protein substrate REACT_118780 NOTCH1 Intracellular Domain Regulates Transcription Reactome Pathway MYC protein substrate REACT_1574 Cyclin E associated events during G1/S transition Reactome Pathway MYC protein substrate REACT_200799 binding of TCF/LEF:CTNNB1 to target gene promoters Reactome Pathway MYC protein substrate REACT_120734 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome Pathway MYC protein substrate REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Reactome Pathway MYC protein substrate REACT_160243 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome Pathway SLC4A1 protein substrate REACT_19298 Bicarbonate transporters Reactome Pathway SLC4A1 protein substrate REACT_121380 Erythrocytes take up oxygen and release carbon dioxide Reactome Pathway SLC4A1 protein substrate REACT_121329 Erythrocytes take up carbon dioxide and release oxygen Reactome Pathway ESR1 protein substrate REACT_116022 Nuclear signaling by ERBB4 Reactome Pathway ESR1 protein substrate REACT_15525 Nuclear Receptor transcription pathway Reactome Pathway RAF1 protein substrate REACT_160189 Stimuli-sensing channels Reactome Pathway RAF1 protein substrate REACT_23847 GP1b-IX-V activation signalling Reactome Pathway RAF1 protein substrate REACT_962 MEK activation Reactome Pathway RAF1 protein substrate REACT_614 RAF phosphorylates MEK Reactome Pathway RAF1 protein substrate REACT_20568 CREB phosphorylation through the activation of Ras Reactome Pathway RAF1 protein substrate REACT_23898 Rap1 signalling Reactome Pathway RAF1 protein substrate REACT_2077 RAF activation Reactome Pathway NR3C1 protein substrate REACT_15525 Nuclear Receptor transcription pathway Reactome Pathway NR3C1 protein substrate REACT_111118 BMAL1:CLOCK,NPAS2 activates circadian gene expression Reactome Pathway ERBB2 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway ERBB2 protein substrate REACT_115720 PLCG1 events in ERBB2 signaling Reactome Pathway ERBB2 protein substrate REACT_115662 Downregulation of ERBB2:ERBB3 signaling Reactome Pathway ERBB2 protein substrate REACT_115896 GRB7 events in ERBB2 signaling Reactome Pathway ERBB2 protein substrate REACT_115854 GRB2 events in ERBB2 signaling Reactome Pathway ERBB2 protein substrate REACT_116008 PI3K events in ERBB2 signaling Reactome Pathway ERBB2 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway ERBB2 protein substrate REACT_115993 SHC1 events in ERBB2 signaling Reactome Pathway ERBB2 protein substrate REACT_19277 Sema4D induced cell migration and growth-cone collapse Reactome Pathway ERBB2 protein substrate REACT_115755 Signaling by ERBB2 Reactome Pathway NTRK1 protein substrate REACT_12464 PI3K/AKT activation Reactome Pathway NTRK1 protein substrate REACT_12079 PLC-gamma1 signalling Reactome Pathway NTRK1 protein substrate REACT_12435 Retrograde neurotrophin signalling Reactome Pathway NTRK1 protein substrate REACT_11046 NGF-independant TRKA activation Reactome Pathway NTRK1 protein substrate REACT_12002 ARMS-mediated activation Reactome Pathway NTRK1 protein substrate REACT_12077 Signalling to p38 via RIT and RIN Reactome Pathway NTRK1 protein substrate REACT_12076 Frs2-mediated activation Reactome Pathway NTRK1 protein substrate REACT_12033 Signalling to RAS Reactome Pathway NTRK1 protein substrate REACT_12049 Signalling to STAT3 Reactome Pathway NTRK1 protein substrate REACT_11060 TRKA activation by NGF Reactome Pathway TP53 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway TP53 protein substrate REACT_118568 Pre-NOTCH Transcription and Translation Reactome Pathway TP53 protein substrate REACT_24970 Factors involved in megakaryocyte development and platelet production Reactome Pathway TP53 protein substrate REACT_121 Activation of PUMA and translocation to mitochondria Reactome Pathway TP53 protein substrate REACT_309 Stabilization of p53 Reactome Pathway TP53 protein substrate REACT_169121 Formation of Senescence-Associated Heterochromatin Foci (SAHF) Reactome Pathway TP53 protein substrate REACT_169325 Oncogene Induced Senescence Reactome Pathway TP53 protein substrate REACT_20549 Autodegradation of the E3 ubiquitin ligase COP1 Reactome Pathway TP53 protein substrate REACT_346 Transcriptional activation of cell cycle inhibitor p21 Reactome Pathway TP53 protein substrate REACT_169185 DNA Damage/Telomere Stress Induced Senescence Reactome Pathway TP53 protein substrate REACT_1194 Activation of NOXA and translocation to mitochondria Reactome Pathway HSPB1 protein substrate REACT_25325 AUF1 (hnRNP D0) destabilizes mRNA Reactome Pathway EIF2S1 protein substrate REACT_931 Ribosomal scanning and start codon recognition Reactome Pathway EIF2S1 protein substrate REACT_1979 Translation initiation complex formation Reactome Pathway EIF2S1 protein substrate REACT_2085 GTP hydrolysis and joining of the 60S ribosomal subunit Reactome Pathway EIF2S1 protein substrate REACT_1079 Formation of the ternary complex, and subsequently, the 43S complex Reactome Pathway EIF2S1 protein substrate REACT_1815 Recycling of eIF2:GDP Reactome Pathway EIF2S1 protein substrate REACT_18277 PERK regulates gene expression Reactome Pathway EIF2S1 protein substrate REACT_79 L13a-mediated translational silencing of Ceruloplasmin expression Reactome Pathway JUN protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway JUN protein substrate REACT_118568 Pre-NOTCH Transcription and Translation Reactome Pathway JUN protein substrate REACT_21326 Activation of the AP-1 family of transcription factors Reactome Pathway JUN protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway JUN protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway ITGB1 protein substrate REACT_20617 Localization of the PINCH-ILK-PARVIN complex to focal adhesions Reactome Pathway ITGB1 protein substrate REACT_160131 Fibronectin matrix formation Reactome Pathway ITGB1 protein substrate REACT_1230 Platelet Adhesion to exposed collagen Reactome Pathway ITGB1 protein substrate REACT_12051 Cell surface interactions at the vascular wall Reactome Pathway ITGB1 protein substrate REACT_150366 Elastic fibre formation Reactome Pathway ITGB1 protein substrate REACT_163942 Syndecan interactions Reactome Pathway ITGB1 protein substrate REACT_169262 Laminin interactions Reactome Pathway ITGB1 protein substrate REACT_22272 Signal transduction by L1 Reactome Pathway ITGB1 protein substrate REACT_22292 CHL1 interactions Reactome Pathway ITGB1 protein substrate REACT_11152 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Reactome Pathway ITGB1 protein substrate REACT_13552 Integrin cell surface interactions Reactome Pathway ITGB1 protein substrate REACT_150331 Molecules associated with elastic fibres Reactome Pathway ITGB1 protein substrate REACT_12560 Basigin interactions Reactome Pathway ITGB1 protein substrate REACT_19200 Other semaphorin interactions Reactome Pathway ITGB1 protein substrate REACT_163906 ECM proteoglycans Reactome Pathway PRKCB protein substrate REACT_172599 WNT5A-dependent internalization of FZD4 Reactome Pathway PRKCB protein substrate REACT_200828 Depolymerisation of the Nuclear Lamina Reactome Pathway PRKCB protein substrate REACT_1280 Response to elevated platelet cytosolic Ca2+ Reactome Pathway PRKCB protein substrate REACT_19333 G alpha (z) signalling events Reactome Pathway PRKCB protein substrate REACT_118656 Activation of NF-kappaB in B cells Reactome Pathway PRKCB protein substrate REACT_1178 Disinhibition of SNARE formation Reactome Pathway PRKCB protein substrate REACT_18422 Trafficking of GluR2-containing AMPA receptors Reactome Pathway CSN2 protein substrate REACT_116022 Nuclear signaling by ERBB4 Reactome Pathway INSR protein substrate REACT_1661 SHC activation Reactome Pathway INSR protein substrate REACT_1109 Insulin receptor recycling Reactome Pathway INSR protein substrate REACT_498 Signaling by Insulin receptor Reactome Pathway INSR protein substrate REACT_508 Signal attenuation Reactome Pathway INSR protein substrate REACT_570 IRS activation Reactome Pathway LCK protein substrate REACT_111225 Regulation of KIT signaling Reactome Pathway LCK protein substrate REACT_1695 GPVI-mediated activation cascade Reactome Pathway LCK protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway LCK protein substrate REACT_12596 Translocation of ZAP-70 to Immunological synapse Reactome Pathway LCK protein substrate REACT_19238 CD28 dependent Vav1 pathway Reactome Pathway LCK protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway LCK protein substrate REACT_19183 CD28 co-stimulation Reactome Pathway LCK protein substrate REACT_19358 CD28 dependent PI3K/Akt signaling Reactome Pathway LCK protein substrate REACT_12623 Generation of second messenger molecules Reactome Pathway LCK protein substrate REACT_11068 Nef and signal transduction Reactome Pathway LCK protein substrate REACT_11166 Nef Mediated CD4 Down-regulation Reactome Pathway LCK protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway LCK protein substrate REACT_12555 Downstream TCR signaling Reactome Pathway LCK protein substrate REACT_12582 Phosphorylation of CD3 and TCR zeta chains Reactome Pathway LCK protein substrate REACT_19324 PD-1 signaling Reactome Pathway LCK protein substrate REACT_27283 Interleukin-2 signaling Reactome Pathway LCK protein substrate REACT_12519 PECAM1 interactions Reactome Pathway LCK protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway LCK protein substrate REACT_147814 DAP12 signaling Reactome Pathway FYN protein substrate REACT_1230 Platelet Adhesion to exposed collagen Reactome Pathway FYN protein substrate REACT_12051 Cell surface interactions at the vascular wall Reactome Pathway FYN protein substrate REACT_19238 CD28 dependent Vav1 pathway Reactome Pathway FYN protein substrate REACT_118700 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Reactome Pathway FYN protein substrate REACT_19183 CD28 co-stimulation Reactome Pathway FYN protein substrate REACT_18334 NCAM signaling for neurite out-growth Reactome Pathway FYN protein substrate REACT_19358 CD28 dependent PI3K/Akt signaling Reactome Pathway FYN protein substrate REACT_163769 Role of LAT2/NTAL/LAB on calcium mobilization Reactome Pathway FYN protein substrate REACT_160274 FCGR activation Reactome Pathway FYN protein substrate REACT_23832 Nephrin interactions Reactome Pathway FYN protein substrate REACT_22351 DCC mediated attractive signaling Reactome Pathway FYN protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway FYN protein substrate REACT_22384 Netrin mediated repulsion signals Reactome Pathway FYN protein substrate REACT_12519 PECAM1 interactions Reactome Pathway FYN protein substrate REACT_111225 Regulation of KIT signaling Reactome Pathway FYN protein substrate REACT_1695 GPVI-mediated activation cascade Reactome Pathway FYN protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway FYN protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway FYN protein substrate REACT_11068 Nef and signal transduction Reactome Pathway FYN protein substrate REACT_19199 CRMPs in Sema3A signaling Reactome Pathway FYN protein substrate REACT_19279 SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion Reactome Pathway FYN protein substrate REACT_23787 Regulation of signaling by CBL Reactome Pathway FYN protein substrate REACT_19236 Sema3A PAK dependent Axon repulsion Reactome Pathway FYN protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway FYN protein substrate REACT_115755 Signaling by ERBB2 Reactome Pathway FYN protein substrate REACT_147814 DAP12 signaling Reactome Pathway RB1 protein substrate REACT_308 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes Reactome Pathway RB1 protein substrate REACT_1574 Cyclin E associated events during G1/S transition Reactome Pathway RB1 protein substrate REACT_329 Inhibition of replication initiation of damaged DNA by RB1/E2F1 Reactome Pathway RB1 protein substrate REACT_172744 Condensation of Prophase Chromosomes Reactome Pathway RB1 protein substrate REACT_1156 Orc1 removal from chromatin Reactome Pathway RB1 protein substrate REACT_1156 Orc1 removal from chromatin Reactome Pathway RB1 protein substrate REACT_169121 Formation of Senescence-Associated Heterochromatin Foci (SAHF) Reactome Pathway RB1 protein substrate REACT_821 Cyclin D associated events in G1 Reactome Pathway RB1 protein substrate REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Reactome Pathway CDK1 protein substrate REACT_407 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex Reactome Pathway CDK1 protein substrate REACT_111214 G0 and Early G1 Reactome Pathway CDK1 protein substrate REACT_683 G1/S-Specific Transcription Reactome Pathway CDK1 protein substrate REACT_1391 ERK1 activation Reactome Pathway CDK1 protein substrate REACT_172744 Condensation of Prophase Chromosomes Reactome Pathway CDK1 protein substrate REACT_160122 Activation of NIMA Kinases NEK9, NEK6, NEK7 Reactome Pathway CDK1 protein substrate REACT_163931 Nuclear Pore Complex (NPC) Disassembly Reactome Pathway CDK1 protein substrate REACT_2101 Cyclin B2 mediated events Reactome Pathway CDK1 protein substrate REACT_6362 Phosphorylation of proteins involved in the G2/M transition by Cyclin A:Cdc2 complexes Reactome Pathway CDK1 protein substrate REACT_6820 APC/C:Cdc20 mediated degradation of Cyclin B Reactome Pathway CDK1 protein substrate REACT_200828 Depolymerisation of the Nuclear Lamina Reactome Pathway CDK1 protein substrate REACT_1391 ERK1 activation Reactome Pathway CDK1 protein substrate REACT_6875 Phosphorylation of Emi1 Reactome Pathway CDK1 protein substrate REACT_15510 Recruitment of NuMA to mitotic centrosomes Reactome Pathway CDK1 protein substrate REACT_1100 Golgi Cisternae Pericentriolar Stack Reorganization Reactome Pathway CDK1 protein substrate REACT_6904 Phosphorylation of the APC/C Reactome Pathway CDK1 protein substrate REACT_6837 Regulation of APC/C activators between G1/S and early anaphase Reactome Pathway CDK1 protein substrate REACT_1846 G2/M DNA replication checkpoint Reactome Pathway CDK1 protein substrate REACT_150260 Condensation of Prometaphase Chromosomes Reactome Pathway CDK1 protein substrate REACT_15364 Loss of Nlp from mitotic centrosomes Reactome Pathway CDK1 protein substrate REACT_150425 Resolution of Sister Chromatid Cohesion Reactome Pathway CDK1 protein substrate REACT_15296 Recruitment of mitotic centrosome proteins and complexes Reactome Pathway CDK1 protein substrate REACT_160315 Regulation of PLK1 Activity at G2/M Transition Reactome Pathway CDK1 protein substrate REACT_150182 MASTL Facilitates Mitotic Progression Reactome Pathway CDK1 protein substrate REACT_1857 Cyclin A/B1 associated events during G2/M transition Reactome Pathway CDK1 protein substrate REACT_471 E2F mediated regulation of DNA replication Reactome Pathway CDK1 protein substrate REACT_1321 E2F-enabled inhibition of pre-replication complex formation Reactome Pathway CDK1 protein substrate REACT_15451 Loss of proteins required for interphase microtubule organization from the centrosome Reactome Pathway YES1 protein substrate REACT_160274 FCGR activation Reactome Pathway YES1 protein substrate REACT_23787 Regulation of signaling by CBL Reactome Pathway YES1 protein substrate REACT_111225 Regulation of KIT signaling Reactome Pathway YES1 protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway YES1 protein substrate REACT_12519 PECAM1 interactions Reactome Pathway YES1 protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway YES1 protein substrate REACT_19183 CD28 co-stimulation Reactome Pathway YES1 protein substrate REACT_115755 Signaling by ERBB2 Reactome Pathway LYN protein substrate REACT_111225 Regulation of KIT signaling Reactome Pathway LYN protein substrate REACT_1695 GPVI-mediated activation cascade Reactome Pathway LYN protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway LYN protein substrate REACT_1230 Platelet Adhesion to exposed collagen Reactome Pathway LYN protein substrate REACT_12051 Cell surface interactions at the vascular wall Reactome Pathway LYN protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway LYN protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway LYN protein substrate REACT_118700 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Reactome Pathway LYN protein substrate REACT_19183 CD28 co-stimulation Reactome Pathway LYN protein substrate REACT_163936 Fc epsilon receptor (FCERI) signaling Reactome Pathway LYN protein substrate REACT_163769 Role of LAT2/NTAL/LAB on calcium mobilization Reactome Pathway LYN protein substrate REACT_160274 FCGR activation Reactome Pathway LYN protein substrate REACT_23787 Regulation of signaling by CBL Reactome Pathway LYN protein substrate REACT_163834 FCERI mediated Ca+2 mobilization Reactome Pathway LYN protein substrate REACT_163994 FCERI mediated NF-kB activation Reactome Pathway LYN protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway LYN protein substrate REACT_12519 PECAM1 interactions Reactome Pathway IGF1R protein substrate REACT_150203 IRS-related events triggered by IGF1R Reactome Pathway IGF1R protein substrate REACT_150359 Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) Reactome Pathway IGF1R protein substrate REACT_150139 SHC-related events triggered by IGF1R Reactome Pathway RHO protein substrate REACT_163932 Activation of the phototransduction cascade Reactome Pathway RHO protein substrate REACT_19231 G alpha (i) signalling events Reactome Pathway RHO protein substrate REACT_160156 The canonical retinoid cycle in rods (twilight vision) Reactome Pathway RHO protein substrate REACT_18426 Opsins Reactome Pathway RHO protein substrate REACT_163919 Inactivation, recovery and regulation of the phototransduction cascade Reactome Pathway PDHA1 protein substrate REACT_12528 Regulation of pyruvate dehydrogenase (PDH) complex Reactome Pathway PDHA1 protein substrate REACT_2071 Pyruvate metabolism Reactome Pathway MET protein substrate REACT_19266 Sema4D mediated inhibition of cell attachment and migration Reactome Pathway VIM protein substrate REACT_13541 Caspase-mediated cleavage of cytoskeletal proteins Reactome Pathway VIM protein substrate REACT_16969 Striated Muscle Contraction Reactome Pathway PDGFRB protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway PDGFRB protein substrate REACT_16888 Signaling by PDGF Reactome Pathway PDGFRB protein substrate REACT_17025 Downstream signal transduction Reactome Pathway PDGFRB protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway HIST1H2AG, HIST1H2AI, HIST1H2AK, HIST1H2AL, HIST1H2AM protein substrate REACT_172610 HATs acetylate histones Reactome Pathway BCL2 protein substrate REACT_75927 The NLRP1 inflammasome Reactome Pathway BCL2 protein substrate REACT_330 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Reactome Pathway BCL2 protein substrate REACT_549 Activation of BAD and translocation to mitochondria Reactome Pathway MAPT protein substrate REACT_13541 Caspase-mediated cleavage of cytoskeletal proteins Reactome Pathway KIT protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway KIT protein substrate REACT_111225 Regulation of KIT signaling Reactome Pathway KIT protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway KIT protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway GHR protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway GHR protein substrate REACT_115697 Prolactin receptor signaling Reactome Pathway CDK4 protein substrate REACT_27161 Transcriptional regulation of white adipocyte differentiation Reactome Pathway CDK4 protein substrate REACT_27271 Meiotic recombination Reactome Pathway CDK4 protein substrate REACT_4 Ubiquitin-dependent degradation of Cyclin D1 Reactome Pathway CDK4 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway CDK4 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway CDK4 protein substrate REACT_169325 Oncogene Induced Senescence Reactome Pathway CDK4 protein substrate REACT_821 Cyclin D associated events in G1 Reactome Pathway FCGR2A protein substrate REACT_160274 FCGR activation Reactome Pathway FCGR2A protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway FCGR2A protein substrate REACT_160158 Role of phospholipids in phagocytosis Reactome Pathway BCKDHA protein substrate REACT_197 Branched-chain amino acid catabolism Reactome Pathway ACTN1 protein substrate REACT_20580 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components Reactome Pathway ACTN1 protein substrate REACT_318 Platelet degranulation Reactome Pathway ACTN1 protein substrate REACT_23832 Nephrin interactions Reactome Pathway ACTN1 protein substrate REACT_163942 Syndecan interactions Reactome Pathway CDH1 protein substrate REACT_19195 Adherens junctions interactions Reactome Pathway CDH1 protein substrate REACT_11152 Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Reactome Pathway CDH1 protein substrate REACT_118572 Degradation of the extracellular matrix Reactome Pathway CDH1 protein substrate REACT_13552 Integrin cell surface interactions Reactome Pathway CDH1 protein substrate REACT_13579 Apoptotic cleavage of cell adhesion proteins Reactome Pathway SRC protein substrate REACT_111225 Regulation of KIT signaling Reactome Pathway SRC protein substrate REACT_9417 Signaling by EGFR Reactome Pathway SRC protein substrate REACT_15523 Integrin alphaIIb beta3 signaling Reactome Pathway SRC protein substrate REACT_11043 c-src mediated regulation of Cx43 function and closure of gap junctions Reactome Pathway SRC protein substrate REACT_17025 Downstream signal transduction Reactome Pathway SRC protein substrate REACT_15443 GRB2:SOS provides linkage to MAPK signaling for Integrins Reactome Pathway SRC protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway SRC protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway SRC protein substrate REACT_19183 CD28 co-stimulation Reactome Pathway SRC protein substrate REACT_18334 NCAM signaling for neurite out-growth Reactome Pathway SRC protein substrate REACT_12578 GAB1 signalosome Reactome Pathway SRC protein substrate REACT_160274 FCGR activation Reactome Pathway SRC protein substrate REACT_23916 Signal regulatory protein (SIRP) family interactions Reactome Pathway SRC protein substrate REACT_21384 Thrombin signalling through proteinase activated receptors (PARs) Reactome Pathway SRC protein substrate REACT_12065 p38MAPK events Reactome Pathway SRC protein substrate REACT_19140 ADP signalling through P2Y purinoceptor 1 Reactome Pathway SRC protein substrate REACT_111080 Spry regulation of FGF signaling Reactome Pathway SRC protein substrate REACT_23847 GP1b-IX-V activation signalling Reactome Pathway SRC protein substrate REACT_22351 DCC mediated attractive signaling Reactome Pathway SRC protein substrate REACT_22384 Netrin mediated repulsion signals Reactome Pathway SRC protein substrate REACT_12519 PECAM1 interactions Reactome Pathway SRC protein substrate REACT_15381 p130Cas linkage to MAPK signaling for integrins Reactome Pathway SRC protein substrate REACT_22365 Recycling pathway of L1 Reactome Pathway SRC protein substrate REACT_115755 Signaling by ERBB2 Reactome Pathway EEF2 protein substrate REACT_1404 Peptide chain elongation Reactome Pathway PRKAR2A protein substrate REACT_24970 Factors involved in megakaryocyte development and platelet production Reactome Pathway PRKAR2A protein substrate REACT_18274 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Reactome Pathway PRKAR2A protein substrate REACT_15530 PKA activation Reactome Pathway PRKAR2A protein substrate REACT_15530 PKA activation Reactome Pathway PRKAR2A protein substrate REACT_24023 Regulation of water balance by renal Aquaporins Reactome Pathway PRKAR2A protein substrate REACT_1946 PKA activation in glucagon signalling Reactome Pathway PRKAR2A protein substrate REACT_15334 DARPP-32 events Reactome Pathway FABP4 protein substrate REACT_27161 Transcriptional regulation of white adipocyte differentiation Reactome Pathway FABP4 protein substrate REACT_494 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Reactome Pathway ARSA protein substrate REACT_116105 Glycosphingolipid metabolism Reactome Pathway ARSA protein substrate REACT_121036 The activation of arylsulfatases Reactome Pathway EZR protein substrate REACT_22237 Netrin-1 signaling Reactome Pathway EZR protein substrate REACT_22365 Recycling pathway of L1 Reactome Pathway RPA2 protein substrate REACT_1993 Repair synthesis for gap-filling by DNA polymerase in TC-NER Reactome Pathway RPA2 protein substrate REACT_27271 Meiotic recombination Reactome Pathway RPA2 protein substrate REACT_200744 HSF1 activation Reactome Pathway RPA2 protein substrate REACT_1095 Activation of the pre-replicative complex Reactome Pathway RPA2 protein substrate REACT_378 Repair synthesis of patch ~27-30 bases long by DNA polymerase Reactome Pathway RPA2 protein substrate REACT_1095 Activation of the pre-replicative complex Reactome Pathway RPA2 protein substrate REACT_70 Removal of the Flap Intermediate Reactome Pathway RPA2 protein substrate REACT_311 Dual incision reaction in GG-NER Reactome Pathway RPA2 protein substrate REACT_2141 Assembly of the RAD51-ssDNA nucleoprotein complex Reactome Pathway RPA2 protein substrate REACT_200780 Regulation of HSF1-mediated heat shock response Reactome Pathway RPA2 protein substrate REACT_6769 Activation of ATR in response to replication stress Reactome Pathway RPA2 protein substrate REACT_2055 Processing of DNA double-strand break ends Reactome Pathway RPA2 protein substrate REACT_257 Formation of incision complex in GG-NER Reactome Pathway RPA2 protein substrate REACT_7999 Removal of the Flap Intermediate from the C-strand Reactome Pathway RPA2 protein substrate REACT_408 Presynaptic phase of homologous DNA pairing and strand exchange Reactome Pathway H2AFX protein substrate REACT_27271 Meiotic recombination Reactome Pathway H2AFX protein substrate REACT_1884 MRN complex relocalizes to nuclear foci Reactome Pathway H2AFX protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway H2AFX protein substrate REACT_97 Recruitment of repair and signaling proteins to double-strand breaks Reactome Pathway H2AFX protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway H2AFX protein substrate REACT_172744 Condensation of Prophase Chromosomes Reactome Pathway H2AFX protein substrate REACT_1924 ATM mediated phosphorylation of repair proteins Reactome Pathway H2AFX protein substrate REACT_2232 RNA Polymerase I Promoter Opening Reactome Pathway H2AFX protein substrate REACT_22186 Deposition of new CENPA-containing nucleosomes at the centromere Reactome Pathway H2AFX protein substrate REACT_75925 Amyloids Reactome Pathway H2AFX protein substrate REACT_7963 Packaging Of Telomere Ends Reactome Pathway H2AFX protein substrate REACT_2204 RNA Polymerase I Chain Elongation Reactome Pathway H2AFX protein substrate REACT_200827 SIRT1 negatively regulates rRNA Expression Reactome Pathway H2AFX protein substrate REACT_75792 Meiotic synapsis Reactome Pathway H2AFX protein substrate REACT_200856 NoRC negatively regulates rRNA expression Reactome Pathway H2AFX protein substrate REACT_486 Assembly of the RAD50-MRE11-NBS1 complex at DNA double-strand breaks Reactome Pathway H2AFX protein substrate REACT_200753 formation of the beta-catenin:TCF transactivating complex Reactome Pathway H2AFX protein substrate REACT_200808 PRC2 methylates histones and DNA Reactome Pathway H2AFX protein substrate REACT_169185 DNA Damage/Telomere Stress Induced Senescence Reactome Pathway CREB1 protein substrate REACT_20625 CREB phosphorylation through the activation of Adenylate Cyclase Reactome Pathway CREB1 protein substrate REACT_20661 CREB phosphorylation through the activation of CaMKK Reactome Pathway CREB1 protein substrate REACT_12524 CREB phosphorylation Reactome Pathway CREB1 protein substrate REACT_200608 Transcriptional activation of mitochondrial biogenesis Reactome Pathway CREB1 protein substrate REACT_163910 NOTCH2 intracellular domain regulates transcription Reactome Pathway CREB1 protein substrate REACT_18334 NCAM signaling for neurite out-growth Reactome Pathway CREB1 protein substrate REACT_15497 PKA-mediated phosphorylation of CREB Reactome Pathway CREB1 protein substrate REACT_12524 CREB phosphorylation Reactome Pathway CREB1 protein substrate REACT_15502 CaMK IV-mediated phosphorylation of CREB Reactome Pathway CREB1 protein substrate REACT_20568 CREB phosphorylation through the activation of Ras Reactome Pathway CREB1 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway CREB1 protein substrate REACT_120966 Gastrin-CREB signalling pathway via PKC and MAPK Reactome Pathway CREB1 protein substrate REACT_12442 AKT phosphorylates targets in the nucleus Reactome Pathway CREB1 protein substrate REACT_20642 CREB phosphorylation through the activation of CaMKII Reactome Pathway CREB1 protein substrate REACT_15502 CaMK IV-mediated phosphorylation of CREB Reactome Pathway CREB1 protein substrate REACT_15497 PKA-mediated phosphorylation of CREB Reactome Pathway CREB1 protein substrate REACT_24941 Circadian Clock Reactome Pathway SELE protein substrate REACT_12051 Cell surface interactions at the vascular wall Reactome Pathway PRKCA protein substrate REACT_111225 Regulation of KIT signaling Reactome Pathway PRKCA protein substrate REACT_1280 Response to elevated platelet cytosolic Ca2+ Reactome Pathway PRKCA protein substrate REACT_19333 G alpha (z) signalling events Reactome Pathway PRKCA protein substrate REACT_1178 Disinhibition of SNARE formation Reactome Pathway PRKCA protein substrate REACT_163942 Syndecan interactions Reactome Pathway PRKCA protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway PRKCA protein substrate REACT_9000 Calmodulin induced events Reactome Pathway PRKCA protein substrate REACT_25218 HuR stabilizes mRNA Reactome Pathway PRKCA protein substrate REACT_200828 Depolymerisation of the Nuclear Lamina Reactome Pathway PRKCA protein substrate REACT_121096 EGFR Transactivation by Gastrin Reactome Pathway PRKCA protein substrate REACT_172599 WNT5A-dependent internalization of FZD4 Reactome Pathway PRKCA protein substrate REACT_18405 Acetylcholine regulates insulin secretion Reactome Pathway PRKCA protein substrate REACT_163919 Inactivation, recovery and regulation of the phototransduction cascade Reactome Pathway PRKCA protein substrate REACT_9000 Calmodulin induced events Reactome Pathway PRKCA protein substrate REACT_18422 Trafficking of GluR2-containing AMPA receptors Reactome Pathway PRKCA protein substrate REACT_172761 Ca2+ pathway Reactome Pathway PRKACA protein substrate REACT_20625 CREB phosphorylation through the activation of Adenylate Cyclase Reactome Pathway PRKACA protein substrate REACT_494 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Reactome Pathway PRKACA protein substrate REACT_18325 Regulation of insulin secretion Reactome Pathway PRKACA protein substrate REACT_18274 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Reactome Pathway PRKACA protein substrate REACT_15530 PKA activation Reactome Pathway PRKACA protein substrate REACT_15364 Loss of Nlp from mitotic centrosomes Reactome Pathway PRKACA protein substrate REACT_1525 PKA-mediated phosphorylation of key metabolic factors Reactome Pathway PRKACA protein substrate REACT_15497 PKA-mediated phosphorylation of CREB Reactome Pathway PRKACA protein substrate REACT_15296 Recruitment of mitotic centrosome proteins and complexes Reactome Pathway PRKACA protein substrate REACT_23898 Rap1 signalling Reactome Pathway PRKACA protein substrate REACT_160315 Regulation of PLK1 Activity at G2/M Transition Reactome Pathway PRKACA protein substrate REACT_24970 Factors involved in megakaryocyte development and platelet production Reactome Pathway PRKACA protein substrate REACT_23837 Interleukin-3, 5 and GM-CSF signaling Reactome Pathway PRKACA protein substrate REACT_15530 PKA activation Reactome Pathway PRKACA protein substrate REACT_24023 Regulation of water balance by renal Aquaporins Reactome Pathway PRKACA protein substrate REACT_1946 PKA activation in glucagon signalling Reactome Pathway PRKACA protein substrate REACT_1520 Gluconeogenesis Reactome Pathway PRKACA protein substrate REACT_15451 Loss of proteins required for interphase microtubule organization from the centrosome Reactome Pathway PRKACA protein substrate REACT_15334 DARPP-32 events Reactome Pathway PRKACA protein substrate REACT_15497 PKA-mediated phosphorylation of CREB Reactome Pathway PLCG1 protein substrate REACT_121398 Signaling by FGFR mutants Reactome Pathway PLCG1 protein substrate REACT_115720 PLCG1 events in ERBB2 signaling Reactome Pathway PLCG1 protein substrate REACT_12079 PLC-gamma1 signalling Reactome Pathway PLCG1 protein substrate REACT_12478 EGFR interacts with phospholipase C-gamma Reactome Pathway PLCG1 protein substrate REACT_17025 Downstream signal transduction Reactome Pathway PLCG1 protein substrate REACT_118700 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Reactome Pathway PLCG1 protein substrate REACT_12623 Generation of second messenger molecules Reactome Pathway PLCG1 protein substrate REACT_121141 Signaling by FGFR1 fusion mutants Reactome Pathway PLCG1 protein substrate REACT_115831 ISG15 antiviral mechanism Reactome Pathway PLCG1 protein substrate REACT_111064 DAG and IP3 signaling Reactome Pathway PLCG1 protein substrate REACT_160158 Role of phospholipids in phagocytosis Reactome Pathway PLCG1 protein substrate REACT_163834 FCERI mediated Ca+2 mobilization Reactome Pathway PLCG1 protein substrate REACT_115852 Signaling by constitutively active EGFR Reactome Pathway PLCG1 protein substrate REACT_22228 Role of second messengers in netrin-1 signaling Reactome Pathway PLCG1 protein substrate REACT_21310 Phospholipase C-mediated cascade Reactome Pathway PLCG1 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway PLCG1 protein substrate REACT_12076 Frs2-mediated activation Reactome Pathway PLCG1 protein substrate REACT_12519 PECAM1 interactions Reactome Pathway PLCG1 protein substrate REACT_150312 Synthesis of IP3 and IP4 in the cytosol Reactome Pathway PLCG1 protein substrate REACT_147814 DAP12 signaling Reactome Pathway ELK1 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway ELK1 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway TNNI3 protein substrate REACT_16969 Striated Muscle Contraction Reactome Pathway EIF2AK2 protein substrate REACT_115831 ISG15 antiviral mechanism Reactome Pathway EIF2AK2 protein substrate REACT_6350 Inhibition of PKR Reactome Pathway FLNA protein substrate REACT_318 Platelet degranulation Reactome Pathway FLNA protein substrate REACT_20649 Cell-extracellular matrix interactions Reactome Pathway FLNA protein substrate REACT_23847 GP1b-IX-V activation signalling Reactome Pathway FGFR2 protein substrate REACT_121398 Signaling by FGFR mutants Reactome Pathway FGFR2 protein substrate REACT_976 PI3K Cascade Reactome Pathway FGFR2 protein substrate REACT_111184 Negative regulation of FGFR signaling Reactome Pathway FGFR2 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway FGFR2 protein substrate REACT_120863 Activated point mutants of FGFR2 Reactome Pathway FGFR2 protein substrate REACT_976 PI3K Cascade Reactome Pathway FGFR2 protein substrate REACT_9416 FGFR2b ligand binding and activation Reactome Pathway FGFR2 protein substrate REACT_21374 SHC-mediated cascade Reactome Pathway FGFR2 protein substrate REACT_121255 Signaling by FGFR2 amplification mutants Reactome Pathway FGFR2 protein substrate REACT_9413 FGFR2c ligand binding and activation Reactome Pathway FGFR2 protein substrate REACT_21247 FRS2-mediated cascade Reactome Pathway FGFR2 protein substrate REACT_21310 Phospholipase C-mediated cascade Reactome Pathway FGFR2 protein substrate REACT_21270 PI-3K cascade Reactome Pathway FGFR2 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway RYR1 protein substrate REACT_160189 Stimuli-sensing channels Reactome Pathway CBL protein substrate REACT_23787 Regulation of signaling by CBL Reactome Pathway CBL protein substrate REACT_120850 TGF-beta receptor signaling activates SMADs Reactome Pathway CBL protein substrate REACT_111184 Negative regulation of FGFR signaling Reactome Pathway CBL protein substrate REACT_111225 Regulation of KIT signaling Reactome Pathway CBL protein substrate REACT_12484 EGFR downregulation Reactome Pathway CBL protein substrate REACT_111080 Spry regulation of FGF signaling Reactome Pathway CBL protein substrate REACT_115852 Signaling by constitutively active EGFR Reactome Pathway CBL protein substrate REACT_27307 Interleukin-6 signaling Reactome Pathway CBL protein substrate REACT_118700 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Reactome Pathway RPS6KB1 protein substrate REACT_6754 S6K1-mediated signalling Reactome Pathway RPS6KB1 protein substrate REACT_6754 S6K1-mediated signalling Reactome Pathway RPS6KB1 protein substrate REACT_6772 S6K1 signalling Reactome Pathway RPS6KB1 protein substrate REACT_6772 S6K1 signalling Reactome Pathway JAK1 protein substrate REACT_115831 ISG15 antiviral mechanism Reactome Pathway JAK1 protein substrate REACT_25216 Regulation of IFNA signaling Reactome Pathway JAK1 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway JAK1 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway JAK1 protein substrate REACT_115529 Interleukin-7 signaling Reactome Pathway JAK1 protein substrate REACT_27307 Interleukin-6 signaling Reactome Pathway JAK1 protein substrate REACT_27283 Interleukin-2 signaling Reactome Pathway JAK1 protein substrate REACT_25162 Interferon alpha/beta signaling Reactome Pathway JAK1 protein substrate REACT_25078 Interferon gamma signaling Reactome Pathway JAK1 protein substrate REACT_24980 Regulation of IFNG signaling Reactome Pathway CFL1 protein substrate REACT_318 Platelet degranulation Reactome Pathway CFL1 protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway CFL1 protein substrate REACT_19236 Sema3A PAK dependent Axon repulsion Reactome Pathway POLR2A protein substrate REACT_2222 Dual incision reaction in TC-NER Reactome Pathway POLR2A protein substrate REACT_125 Processing of Capped Intron-Containing Pre-mRNA Reactome Pathway POLR2A protein substrate REACT_22107 RNA Polymerase II Pre-transcription Events Reactome Pathway POLR2A protein substrate REACT_2089 RNA Polymerase II Promoter Escape Reactome Pathway POLR2A protein substrate REACT_1941 Formation of transcription-coupled NER (TC-NER) repair complex Reactome Pathway POLR2A protein substrate REACT_6143 Pausing and recovery of Tat-mediated HIV elongation Reactome Pathway POLR2A protein substrate REACT_6233 Transcription of the HIV genome Reactome Pathway POLR2A protein substrate REACT_6344 Tat-mediated HIV elongation arrest and recovery Reactome Pathway POLR2A protein substrate REACT_6261 Abortive elongation of HIV-1 transcript in the absence of Tat Reactome Pathway POLR2A protein substrate REACT_975 RNA Pol II CTD phosphorylation and interaction with CE Reactome Pathway POLR2A protein substrate REACT_846 Formation of the Early Elongation Complex Reactome Pathway POLR2A protein substrate REACT_6162 Tat-mediated elongation of the HIV-1 transcript Reactome Pathway POLR2A protein substrate REACT_1655 RNA Polymerase II Transcription Pre-Initiation And Promoter Opening Reactome Pathway POLR2A protein substrate REACT_1470 mRNA Capping Reactome Pathway POLR2A protein substrate REACT_12417 MicroRNA (miRNA) biogenesis Reactome Pathway POLR2A protein substrate REACT_6346 Formation of HIV-1 elongation complex containing HIV-1 Tat Reactome Pathway POLR2A protein substrate REACT_834 RNA Polymerase II Transcription Initiation And Promoter Clearance Reactome Pathway POLR2A protein substrate REACT_22201 Formation of HIV elongation complex in the absence of HIV Tat Reactome Pathway POLR2A protein substrate REACT_1753 mRNA Splicing - Minor Pathway Reactome Pathway POLR2A protein substrate REACT_6259 HIV elongation arrest and recovery Reactome Pathway POLR2A protein substrate REACT_6244 Pausing and recovery of HIV elongation Reactome Pathway POLR2A protein substrate REACT_1845 Formation of RNA Pol II elongation complex Reactome Pathway POLR2A protein substrate REACT_1628 Transcription-coupled NER (TC-NER) Reactome Pathway POLR2A protein substrate REACT_833 RNA Polymerase II Transcription Elongation Reactome Pathway POLR2A protein substrate REACT_467 mRNA Splicing - Major Pathway Reactome Pathway POLR2A protein substrate REACT_1851 RNA Polymerase II Transcription Initiation Reactome Pathway POLR2A protein substrate REACT_6319 Formation of the HIV-1 Early Elongation Complex Reactome Pathway POLR2A protein substrate REACT_6354 Viral Messenger RNA Synthesis Reactome Pathway POLR2A protein substrate REACT_6253 RNA Polymerase II HIV Promoter Escape Reactome Pathway POLR2A protein substrate REACT_6332 HIV Transcription Initiation Reactome Pathway POLR2A protein substrate REACT_6237 RNA Pol II CTD phosphorylation and interaction with CE Reactome Pathway CDK2 protein substrate REACT_27271 Meiotic recombination Reactome Pathway CDK2 protein substrate REACT_308 Phosphorylation of proteins involved in G1/S transition by active Cyclin E:Cdk2 complexes Reactome Pathway CDK2 protein substrate REACT_111214 G0 and Early G1 Reactome Pathway CDK2 protein substrate REACT_1574 Cyclin E associated events during G1/S transition Reactome Pathway CDK2 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway CDK2 protein substrate REACT_1095 Activation of the pre-replicative complex Reactome Pathway CDK2 protein substrate REACT_1156 Orc1 removal from chromatin Reactome Pathway CDK2 protein substrate REACT_1221 CDK-mediated phosphorylation and removal of Cdc6 Reactome Pathway CDK2 protein substrate REACT_1095 Activation of the pre-replicative complex Reactome Pathway CDK2 protein substrate REACT_9003 SCF(Skp2)-mediated degradation of p27/p21 Reactome Pathway CDK2 protein substrate REACT_9003 SCF(Skp2)-mediated degradation of p27/p21 Reactome Pathway CDK2 protein substrate REACT_1625 p53-Dependent G1 DNA Damage Response Reactome Pathway CDK2 protein substrate REACT_6769 Activation of ATR in response to replication stress Reactome Pathway CDK2 protein substrate REACT_24970 Factors involved in megakaryocyte development and platelet production Reactome Pathway CDK2 protein substrate REACT_1857 Cyclin A/B1 associated events during G2/M transition Reactome Pathway CDK2 protein substrate REACT_1915 G2 Phase Reactome Pathway CDK2 protein substrate REACT_1156 Orc1 removal from chromatin Reactome Pathway CDK2 protein substrate REACT_1221 CDK-mediated phosphorylation and removal of Cdc6 Reactome Pathway CDK2 protein substrate REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Reactome Pathway CDK2 protein substrate REACT_6837 Regulation of APC/C activators between G1/S and early anaphase Reactome Pathway CDK2 protein substrate REACT_169185 DNA Damage/Telomere Stress Induced Senescence Reactome Pathway NFKBIA protein substrate REACT_118563 RIP-mediated NFkB activation via ZBP1 Reactome Pathway NFKBIA protein substrate REACT_12555 Downstream TCR signaling Reactome Pathway NFKBIA protein substrate REACT_163994 FCERI mediated NF-kB activation Reactome Pathway NFKBIA protein substrate REACT_13696 NF-kB is activated and signals survival Reactome Pathway NFKBIA protein substrate REACT_21281 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Reactome Pathway NFKBIA protein substrate REACT_118656 Activation of NF-kappaB in B cells Reactome Pathway NFKBIA protein substrate REACT_24969 TRAF6 mediated NF-kB activation Reactome Pathway MSN protein substrate REACT_22365 Recycling pathway of L1 Reactome Pathway MAPK3 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAPK3 protein substrate REACT_21326 Activation of the AP-1 family of transcription factors Reactome Pathway MAPK3 protein substrate REACT_1391 ERK1 activation Reactome Pathway MAPK3 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway MAPK3 protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway MAPK3 protein substrate REACT_2232 RNA Polymerase I Promoter Opening Reactome Pathway MAPK3 protein substrate REACT_12436 ERKs are inactivated Reactome Pathway MAPK3 protein substrate REACT_508 Signal attenuation Reactome Pathway MAPK3 protein substrate REACT_18334 NCAM signaling for neurite out-growth Reactome Pathway MAPK3 protein substrate REACT_25195 Advanced glycosylation endproduct receptor signaling Reactome Pathway MAPK3 protein substrate REACT_22272 Signal transduction by L1 Reactome Pathway MAPK3 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway MAPK3 protein substrate REACT_115831 ISG15 antiviral mechanism Reactome Pathway MAPK3 protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway MAPK3 protein substrate REACT_111184 Negative regulation of FGFR signaling Reactome Pathway MAPK3 protein substrate REACT_21384 Thrombin signalling through proteinase activated receptors (PARs) Reactome Pathway MAPK3 protein substrate REACT_200780 Regulation of HSF1-mediated heat shock response Reactome Pathway MAPK3 protein substrate REACT_1391 ERK1 activation Reactome Pathway MAPK3 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway MAPK3 protein substrate REACT_12436 ERKs are inactivated Reactome Pathway MAPK3 protein substrate REACT_120966 Gastrin-CREB signalling pathway via PKC and MAPK Reactome Pathway MAPK3 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway MAPK3 protein substrate REACT_9470 Signaling by FGFR Reactome Pathway MAPK3 protein substrate REACT_169325 Oncogene Induced Senescence Reactome Pathway CAD protein substrate REACT_21376 Pyrimidine biosynthesis Reactome Pathway CANX protein substrate REACT_121399 MHC class II antigen presentation Reactome Pathway CANX protein substrate REACT_6277 Assembly of Viral Components at the Budding Site Reactome Pathway CANX protein substrate REACT_23810 Calnexin/calreticulin cycle Reactome Pathway CANX protein substrate REACT_75795 Antigen Presentation: Folding, assembly and peptide loading of class I MHC Reactome Pathway PIK3R1 protein substrate REACT_121398 Signaling by FGFR mutants Reactome Pathway PIK3R1 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway PIK3R1 protein substrate REACT_17025 Downstream signal transduction Reactome Pathway PIK3R1 protein substrate REACT_116008 PI3K events in ERBB2 signaling Reactome Pathway PIK3R1 protein substrate REACT_118700 Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Reactome Pathway PIK3R1 protein substrate REACT_19358 CD28 dependent PI3K/Akt signaling Reactome Pathway PIK3R1 protein substrate REACT_121141 Signaling by FGFR1 fusion mutants Reactome Pathway PIK3R1 protein substrate REACT_163769 Role of LAT2/NTAL/LAB on calcium mobilization Reactome Pathway PIK3R1 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway PIK3R1 protein substrate REACT_160158 Role of phospholipids in phagocytosis Reactome Pathway PIK3R1 protein substrate REACT_12555 Downstream TCR signaling Reactome Pathway PIK3R1 protein substrate REACT_23847 GP1b-IX-V activation signalling Reactome Pathway PIK3R1 protein substrate REACT_23832 Nephrin interactions Reactome Pathway PIK3R1 protein substrate REACT_12621 Tie2 Signaling Reactome Pathway PIK3R1 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway PIK3R1 protein substrate REACT_121025 Synthesis of PIPs at the plasma membrane Reactome Pathway PIK3R1 protein substrate REACT_1695 GPVI-mediated activation cascade Reactome Pathway PIK3R1 protein substrate REACT_18407 G alpha (12/13) signalling events Reactome Pathway PIK3R1 protein substrate REACT_18283 G alpha (q) signalling events Reactome Pathway PIK3R1 protein substrate REACT_976 PI3K Cascade Reactome Pathway PIK3R1 protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway PIK3R1 protein substrate REACT_19344 Costimulation by the CD28 family Reactome Pathway PIK3R1 protein substrate REACT_12578 GAB1 signalosome Reactome Pathway PIK3R1 protein substrate REACT_18283 G alpha (q) signalling events Reactome Pathway PIK3R1 protein substrate REACT_23787 Regulation of signaling by CBL Reactome Pathway PIK3R1 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway PIK3R1 protein substrate REACT_976 PI3K Cascade Reactome Pathway PIK3R1 protein substrate REACT_12464 PI3K/AKT activation Reactome Pathway PIK3R1 protein substrate REACT_115852 Signaling by constitutively active EGFR Reactome Pathway PIK3R1 protein substrate REACT_23837 Interleukin-3, 5 and GM-CSF signaling Reactome Pathway PIK3R1 protein substrate REACT_21270 PI-3K cascade Reactome Pathway PIK3R1 protein substrate REACT_115529 Interleukin-7 signaling Reactome Pathway PIK3R1 protein substrate REACT_115961 PI3K events in ERBB4 signaling Reactome Pathway PIK3R1 protein substrate REACT_147814 DAP12 signaling Reactome Pathway MAPK1 protein substrate REACT_21326 Activation of the AP-1 family of transcription factors Reactome Pathway MAPK1 protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway MAPK1 protein substrate REACT_12436 ERKs are inactivated Reactome Pathway MAPK1 protein substrate REACT_508 Signal attenuation Reactome Pathway MAPK1 protein substrate REACT_25195 Advanced glycosylation endproduct receptor signaling Reactome Pathway MAPK1 protein substrate REACT_18334 NCAM signaling for neurite out-growth Reactome Pathway MAPK1 protein substrate REACT_111184 Negative regulation of FGFR signaling Reactome Pathway MAPK1 protein substrate REACT_21384 Thrombin signalling through proteinase activated receptors (PARs) Reactome Pathway MAPK1 protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway MAPK1 protein substrate REACT_20510 RSK activation Reactome Pathway MAPK1 protein substrate REACT_12436 ERKs are inactivated Reactome Pathway MAPK1 protein substrate REACT_1100 Golgi Cisternae Pericentriolar Stack Reorganization Reactome Pathway MAPK1 protein substrate REACT_120966 Gastrin-CREB signalling pathway via PKC and MAPK Reactome Pathway MAPK1 protein substrate REACT_169325 Oncogene Induced Senescence Reactome Pathway MAPK1 protein substrate REACT_9470 Signaling by FGFR Reactome Pathway MAPK1 protein substrate REACT_22365 Recycling pathway of L1 Reactome Pathway MAPK1 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAPK1 protein substrate REACT_1183 ERK2 activation Reactome Pathway MAPK1 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway MAPK1 protein substrate REACT_15466 phospho-PLA2 pathway Reactome Pathway MAPK1 protein substrate REACT_1183 ERK2 activation Reactome Pathway MAPK1 protein substrate REACT_20568 CREB phosphorylation through the activation of Ras Reactome Pathway MAPK1 protein substrate REACT_22272 Signal transduction by L1 Reactome Pathway MAPK1 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway MAPK1 protein substrate REACT_200780 Regulation of HSF1-mediated heat shock response Reactome Pathway MAPK1 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway MAPK1 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway RBL1 protein substrate REACT_111214 G0 and Early G1 Reactome Pathway RBL1 protein substrate REACT_821 Cyclin D associated events in G1 Reactome Pathway RBL1 protein substrate REACT_120734 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome Pathway EPHB2 protein substrate REACT_22205 L1CAM interactions Reactome Pathway SHC1 protein substrate REACT_12579 SHC1 events in EGFR signaling Reactome Pathway SHC1 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway SHC1 protein substrate REACT_15523 Integrin alphaIIb beta3 signaling Reactome Pathway SHC1 protein substrate REACT_661 SHC-mediated signalling Reactome Pathway SHC1 protein substrate REACT_508 Signal attenuation Reactome Pathway SHC1 protein substrate REACT_661 SHC-mediated signalling Reactome Pathway SHC1 protein substrate REACT_18273 XBP1(S) activates chaperone genes Reactome Pathway SHC1 protein substrate REACT_116005 SHC1 events in ERBB4 signaling Reactome Pathway SHC1 protein substrate REACT_1661 SHC activation Reactome Pathway SHC1 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway SHC1 protein substrate REACT_115852 Signaling by constitutively active EGFR Reactome Pathway SHC1 protein substrate REACT_12621 Tie2 Signaling Reactome Pathway SHC1 protein substrate REACT_23837 Interleukin-3, 5 and GM-CSF signaling Reactome Pathway SHC1 protein substrate REACT_27283 Interleukin-2 signaling Reactome Pathway SHC1 protein substrate REACT_12033 Signalling to RAS Reactome Pathway SHC1 protein substrate REACT_115993 SHC1 events in ERBB2 signaling Reactome Pathway NOS3 protein substrate REACT_12541 NOSTRIN mediated eNOS trafficking Reactome Pathway NOS3 protein substrate REACT_23862 Nitric oxide stimulates guanylate cyclase Reactome Pathway NOS3 protein substrate REACT_12510 NOSIP mediated eNOS trafficking Reactome Pathway NOS3 protein substrate REACT_121256 Phagosomal maturation (early endosomal stage) Reactome Pathway NOS3 protein substrate REACT_12477 eNOS activation Reactome Pathway NOS3 protein substrate REACT_111176 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Reactome Pathway NOS1 protein substrate REACT_23862 Nitric oxide stimulates guanylate cyclase Reactome Pathway NOS1 protein substrate REACT_121256 Phagosomal maturation (early endosomal stage) Reactome Pathway TYK2 protein substrate REACT_25216 Regulation of IFNA signaling Reactome Pathway TYK2 protein substrate REACT_27307 Interleukin-6 signaling Reactome Pathway TYK2 protein substrate REACT_25162 Interferon alpha/beta signaling Reactome Pathway AKT1 protein substrate REACT_115662 Downregulation of ERBB2:ERBB3 signaling Reactome Pathway AKT1 protein substrate REACT_12447 Negative regulation of the PI3K/AKT network Reactome Pathway AKT1 protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway AKT1 protein substrate REACT_1695 GPVI-mediated activation cascade Reactome Pathway AKT1 protein substrate REACT_15523 Integrin alphaIIb beta3 signaling Reactome Pathway AKT1 protein substrate REACT_25042 KSRP destabilizes mRNA Reactome Pathway AKT1 protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway AKT1 protein substrate REACT_19290 G beta:gamma signalling through PI3Kgamma Reactome Pathway AKT1 protein substrate REACT_19358 CD28 dependent PI3K/Akt signaling Reactome Pathway AKT1 protein substrate REACT_24915 Butyrate Response Factor 1 (BRF1) destabilizes mRNA Reactome Pathway AKT1 protein substrate REACT_111176 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation Reactome Pathway AKT1 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway AKT1 protein substrate REACT_200731 deactivation of the beta-catenin transactivating complex Reactome Pathway AKT1 protein substrate REACT_13655 AKT-mediated inactivation of FOXO1A Reactome Pathway AKT1 protein substrate REACT_147867 Translocation of GLUT4 to the plasma membrane Reactome Pathway AKT1 protein substrate REACT_12442 AKT phosphorylates targets in the nucleus Reactome Pathway AKT1 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway AKT1 protein substrate REACT_12477 eNOS activation Reactome Pathway AKT1 protein substrate REACT_549 Activation of BAD and translocation to mitochondria Reactome Pathway AKT2 protein substrate REACT_115662 Downregulation of ERBB2:ERBB3 signaling Reactome Pathway AKT2 protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway AKT2 protein substrate REACT_12447 Negative regulation of the PI3K/AKT network Reactome Pathway AKT2 protein substrate REACT_1695 GPVI-mediated activation cascade Reactome Pathway AKT2 protein substrate REACT_6743 Inhibition of TSC complex formation by PKB Reactome Pathway AKT2 protein substrate REACT_6743 Inhibition of TSC complex formation by PKB Reactome Pathway AKT2 protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway AKT2 protein substrate REACT_19290 G beta:gamma signalling through PI3Kgamma Reactome Pathway AKT2 protein substrate REACT_1451 PDE3B signalling Reactome Pathway AKT2 protein substrate REACT_19358 CD28 dependent PI3K/Akt signaling Reactome Pathway AKT2 protein substrate REACT_790 Activation of PKB Reactome Pathway AKT2 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway AKT2 protein substrate REACT_200731 deactivation of the beta-catenin transactivating complex Reactome Pathway AKT2 protein substrate REACT_13655 AKT-mediated inactivation of FOXO1A Reactome Pathway AKT2 protein substrate REACT_147867 Translocation of GLUT4 to the plasma membrane Reactome Pathway AKT2 protein substrate REACT_12442 AKT phosphorylates targets in the nucleus Reactome Pathway AKT2 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway AKT2 protein substrate REACT_790 Activation of PKB Reactome Pathway AKT2 protein substrate REACT_549 Activation of BAD and translocation to mitochondria Reactome Pathway AKT2 protein substrate REACT_1451 PDE3B signalling Reactome Pathway CTNNB1 protein substrate REACT_163743 LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production Reactome Pathway CTNNB1 protein substrate REACT_200610 disassembly of the destruction complex and recruitment of AXIN to the membrane Reactome Pathway CTNNB1 protein substrate REACT_200777 TCF dependent signaling in response to WNT Reactome Pathway CTNNB1 protein substrate REACT_200731 deactivation of the beta-catenin transactivating complex Reactome Pathway CTNNB1 protein substrate REACT_200799 binding of TCF/LEF:CTNNB1 to target gene promoters Reactome Pathway CTNNB1 protein substrate REACT_21402 CDO in myogenesis Reactome Pathway CTNNB1 protein substrate REACT_200753 formation of the beta-catenin:TCF transactivating complex Reactome Pathway CTNNB1 protein substrate REACT_172761 Ca2+ pathway Reactome Pathway GCK protein substrate REACT_6804 Regulation of Glucokinase by Glucokinase Regulatory Protein Reactome Pathway GCK protein substrate REACT_212 Glucose transport Reactome Pathway GCK protein substrate REACT_13819 Regulation of gene expression in beta cells Reactome Pathway IRS1 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway IRS1 protein substrate REACT_169118 Signaling by Leptin Reactome Pathway IRS1 protein substrate REACT_12464 PI3K/AKT activation Reactome Pathway IRS1 protein substrate REACT_976 PI3K Cascade Reactome Pathway IRS1 protein substrate REACT_150203 IRS-related events triggered by IGF1R Reactome Pathway IRS1 protein substrate REACT_976 PI3K Cascade Reactome Pathway IRS1 protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway IRS1 protein substrate REACT_508 Signal attenuation Reactome Pathway IRS1 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway IRS1 protein substrate REACT_524 SOS-mediated signalling Reactome Pathway IRS1 protein substrate REACT_524 SOS-mediated signalling Reactome Pathway IRS1 protein substrate REACT_570 IRS activation Reactome Pathway KDR protein substrate REACT_13552 Integrin cell surface interactions Reactome Pathway KDR protein substrate REACT_12473 Neurophilin interactions with VEGF and VEGFR Reactome Pathway KDR protein substrate REACT_12583 VEGF binds to VEGFR leading to receptor dimerization Reactome Pathway BMPR1A protein substrate REACT_12034 Signaling by BMP Reactome Pathway SNCA protein substrate REACT_75925 Amyloids Reactome Pathway BRCA1 protein substrate REACT_27271 Meiotic recombination Reactome Pathway BRCA1 protein substrate REACT_97 Recruitment of repair and signaling proteins to double-strand breaks Reactome Pathway BRCA1 protein substrate REACT_1924 ATM mediated phosphorylation of repair proteins Reactome Pathway BRCA1 protein substrate REACT_75792 Meiotic synapsis Reactome Pathway BRCA1 protein substrate REACT_18410 Fanconi Anemia pathway Reactome Pathway CUX1 protein substrate REACT_121141 Signaling by FGFR1 fusion mutants Reactome Pathway IL6ST protein substrate REACT_27307 Interleukin-6 signaling Reactome Pathway STAT3 protein substrate REACT_200759 POU5F1 (OCT4), SOX2, NANOG activate genes related to proliferation Reactome Pathway STAT3 protein substrate REACT_169118 Signaling by Leptin Reactome Pathway STAT3 protein substrate REACT_200812 Transcriptional regulation of pluripotent stem cells Reactome Pathway STAT3 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway STAT3 protein substrate REACT_17025 Downstream signal transduction Reactome Pathway STAT3 protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway STAT3 protein substrate REACT_27307 Interleukin-6 signaling Reactome Pathway STAT3 protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway STAT3 protein substrate REACT_12049 Signalling to STAT3 Reactome Pathway STAT3 protein substrate REACT_121141 Signaling by FGFR1 fusion mutants Reactome Pathway CETN2 protein substrate REACT_160315 Regulation of PLK1 Activity at G2/M Transition Reactome Pathway CETN2 protein substrate REACT_15364 Loss of Nlp from mitotic centrosomes Reactome Pathway CETN2 protein substrate REACT_15296 Recruitment of mitotic centrosome proteins and complexes Reactome Pathway CETN2 protein substrate REACT_15451 Loss of proteins required for interphase microtubule organization from the centrosome Reactome Pathway PRKCI protein substrate REACT_13415 p75NTR recruits signalling complexes Reactome Pathway PRKCI protein substrate REACT_19373 Tight junction interactions Reactome Pathway STAT1 protein substrate REACT_115831 ISG15 antiviral mechanism Reactome Pathway STAT1 protein substrate REACT_25216 Regulation of IFNA signaling Reactome Pathway STAT1 protein substrate REACT_17025 Downstream signal transduction Reactome Pathway STAT1 protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway STAT1 protein substrate REACT_27307 Interleukin-6 signaling Reactome Pathway STAT1 protein substrate REACT_25162 Interferon alpha/beta signaling Reactome Pathway STAT1 protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway STAT1 protein substrate REACT_25078 Interferon gamma signaling Reactome Pathway STAT1 protein substrate REACT_24980 Regulation of IFNG signaling Reactome Pathway STAT1 protein substrate REACT_121141 Signaling by FGFR1 fusion mutants Reactome Pathway STAT6 protein substrate REACT_17025 Downstream signal transduction Reactome Pathway STAT6 protein substrate REACT_163734 STAT6-mediated induction of chemokines Reactome Pathway STAT5A protein substrate REACT_169118 Signaling by Leptin Reactome Pathway STAT5A protein substrate REACT_116022 Nuclear signaling by ERBB4 Reactome Pathway STAT5A protein substrate REACT_17025 Downstream signal transduction Reactome Pathway STAT5A protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway STAT5A protein substrate REACT_23837 Interleukin-3, 5 and GM-CSF signaling Reactome Pathway STAT5A protein substrate REACT_115529 Interleukin-7 signaling Reactome Pathway STAT5A protein substrate REACT_27283 Interleukin-2 signaling Reactome Pathway STAT5A protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway STAT5A protein substrate REACT_115697 Prolactin receptor signaling Reactome Pathway STAT5A protein substrate REACT_121141 Signaling by FGFR1 fusion mutants Reactome Pathway CASP3 protein substrate REACT_13532 Stimulation of the cell death response by PAK-2p34 Reactome Pathway CASP3 protein substrate REACT_13462 Activation of DNA fragmentation factor Reactome Pathway CASP3 protein substrate REACT_13541 Caspase-mediated cleavage of cytoskeletal proteins Reactome Pathway CASP3 protein substrate REACT_607 Activation of caspases through apoptosome-mediated cleavage Reactome Pathway CASP3 protein substrate REACT_118572 Degradation of the extracellular matrix Reactome Pathway CASP3 protein substrate REACT_13579 Apoptotic cleavage of cell adhesion proteins Reactome Pathway CASP3 protein substrate REACT_107 Apoptotic cleavage of cellular proteins Reactome Pathway CASP3 protein substrate REACT_13526 NADE modulates death signalling Reactome Pathway CASP3 protein substrate REACT_2190 SMAC binds to IAPs Reactome Pathway CASP3 protein substrate REACT_118607 Signaling by Hippo Reactome Pathway CASP3 protein substrate REACT_22128 Role of DCC in regulating apoptosis Reactome Pathway CASP3 protein substrate REACT_1767 SMAC-mediated dissociation of IAP:caspase complexes Reactome Pathway CASP2 protein substrate REACT_13526 NADE modulates death signalling Reactome Pathway CASP2 protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway WAS protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway WAS protein substrate REACT_12623 Generation of second messenger molecules Reactome Pathway ZAP70 protein substrate REACT_12596 Translocation of ZAP-70 to Immunological synapse Reactome Pathway ZAP70 protein substrate REACT_12623 Generation of second messenger molecules Reactome Pathway TNNT2 protein substrate REACT_16969 Striated Muscle Contraction Reactome Pathway MAPK8 protein substrate REACT_1650 Activation of BIM and translocation to mitochondria Reactome Pathway MAPK8 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAPK8 protein substrate REACT_21326 Activation of the AP-1 family of transcription factors Reactome Pathway MAPK8 protein substrate REACT_21368 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Reactome Pathway MAPK8 protein substrate REACT_13638 NRAGE signals death through JNK Reactome Pathway MAPK8 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway MAPK8 protein substrate REACT_25299 DSCAM interactions Reactome Pathway MAPK8 protein substrate REACT_2100 Activation of BMF and translocation to mitochondria Reactome Pathway MAPK8 protein substrate REACT_13643 NRIF signals cell death from the nucleus Reactome Pathway MAPK9 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAPK9 protein substrate REACT_21326 Activation of the AP-1 family of transcription factors Reactome Pathway MAPK9 protein substrate REACT_21368 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Reactome Pathway MAPK9 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway MAP2K4 protein substrate REACT_22442 Interleukin-1 signaling Reactome Pathway MAP2K4 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAP2K4 protein substrate REACT_21368 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Reactome Pathway MAP2K4 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway CRK protein substrate REACT_23787 Regulation of signaling by CBL Reactome Pathway CRK protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway CRK protein substrate REACT_17025 Downstream signal transduction Reactome Pathway CRK protein substrate REACT_12002 ARMS-mediated activation Reactome Pathway CRK protein substrate REACT_508 Signal attenuation Reactome Pathway CRK protein substrate REACT_15381 p130Cas linkage to MAPK signaling for integrins Reactome Pathway NSF protein substrate REACT_18422 Trafficking of GluR2-containing AMPA receptors Reactome Pathway CDKN1B protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway CDKN1B protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway CDKN1B protein substrate REACT_1574 Cyclin E associated events during G1/S transition Reactome Pathway CDKN1B protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway CDKN1B protein substrate REACT_1156 Orc1 removal from chromatin Reactome Pathway CDKN1B protein substrate REACT_1156 Orc1 removal from chromatin Reactome Pathway CDKN1B protein substrate REACT_9003 SCF(Skp2)-mediated degradation of p27/p21 Reactome Pathway CDKN1B protein substrate REACT_821 Cyclin D associated events in G1 Reactome Pathway CDKN1B protein substrate REACT_1625 p53-Dependent G1 DNA Damage Response Reactome Pathway CDKN1B protein substrate REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Reactome Pathway CDKN1B protein substrate REACT_9003 SCF(Skp2)-mediated degradation of p27/p21 Reactome Pathway CDKN1B protein substrate REACT_169185 DNA Damage/Telomere Stress Induced Senescence Reactome Pathway PXN protein substrate REACT_20617 Localization of the PINCH-ILK-PARVIN complex to focal adhesions Reactome Pathway PXN protein substrate REACT_20580 Regulation of cytoskeletal remodeling and cell spreading by IPP complex components Reactome Pathway PXN protein substrate REACT_20558 Smooth Muscle Contraction Reactome Pathway PXN protein substrate REACT_12578 GAB1 signalosome Reactome Pathway MAPKAPK2 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAPKAPK2 protein substrate REACT_200780 Regulation of HSF1-mediated heat shock response Reactome Pathway MAPKAPK2 protein substrate REACT_12065 p38MAPK events Reactome Pathway MAPKAPK2 protein substrate REACT_12524 CREB phosphorylation Reactome Pathway MAPKAPK2 protein substrate REACT_25064 Tristetraprolin (TTP) destabilizes mRNA Reactome Pathway MAPKAPK2 protein substrate REACT_21399 activated TAK1 mediates p38 MAPK activation Reactome Pathway MAPKAPK2 protein substrate REACT_12524 CREB phosphorylation Reactome Pathway MAPKAPK2 protein substrate REACT_24915 Butyrate Response Factor 1 (BRF1) destabilizes mRNA Reactome Pathway MAPKAPK2 protein substrate REACT_150420 Synthesis of Leukotrienes (LT) and Eoxins (EX) Reactome Pathway CSNK1E protein substrate REACT_160315 Regulation of PLK1 Activity at G2/M Transition Reactome Pathway CSNK1E protein substrate REACT_15364 Loss of Nlp from mitotic centrosomes Reactome Pathway CSNK1E protein substrate REACT_200668 WNT mediated activation of DVL Reactome Pathway CSNK1E protein substrate REACT_15296 Recruitment of mitotic centrosome proteins and complexes Reactome Pathway CSNK1E protein substrate REACT_15451 Loss of proteins required for interphase microtubule organization from the centrosome Reactome Pathway CSNK1E protein substrate REACT_24941 Circadian Clock Reactome Pathway GSK3B protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway GSK3B protein substrate REACT_200610 disassembly of the destruction complex and recruitment of AXIN to the membrane Reactome Pathway GSK3B protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway GSK3B protein substrate REACT_200780 Regulation of HSF1-mediated heat shock response Reactome Pathway GSK3B protein substrate REACT_11063 Degradation of beta-catenin by the destruction complex Reactome Pathway GSK3B protein substrate REACT_11065 Beta-catenin phosphorylation cascade Reactome Pathway GSK3B protein substrate REACT_19199 CRMPs in Sema3A signaling Reactome Pathway VASP protein substrate REACT_20649 Cell-extracellular matrix interactions Reactome Pathway VASP protein substrate REACT_19351 Signaling by Robo receptor Reactome Pathway VASP protein substrate REACT_12623 Generation of second messenger molecules Reactome Pathway DNM2 protein substrate REACT_11035 Gap junction degradation Reactome Pathway DNM2 protein substrate REACT_12541 NOSTRIN mediated eNOS trafficking Reactome Pathway DNM2 protein substrate REACT_121399 MHC class II antigen presentation Reactome Pathway DNM2 protein substrate REACT_19287 Lysosome Vesicle Biogenesis Reactome Pathway DNM2 protein substrate REACT_19400 Golgi Associated Vesicle Biogenesis Reactome Pathway DNM2 protein substrate REACT_12435 Retrograde neurotrophin signalling Reactome Pathway DNM2 protein substrate REACT_11049 Formation of annular gap junctions Reactome Pathway DNM2 protein substrate REACT_6894 Toll Like Receptor 4 (TLR4) Cascade Reactome Pathway DNM2 protein substrate REACT_22365 Recycling pathway of L1 Reactome Pathway CDK9 protein substrate REACT_6905 Interactions of Tat with host cellular proteins Reactome Pathway CDK9 protein substrate REACT_22107 RNA Polymerase II Pre-transcription Events Reactome Pathway CDK9 protein substrate REACT_6259 HIV elongation arrest and recovery Reactome Pathway CDK9 protein substrate REACT_6143 Pausing and recovery of Tat-mediated HIV elongation Reactome Pathway CDK9 protein substrate REACT_6244 Pausing and recovery of HIV elongation Reactome Pathway CDK9 protein substrate REACT_1845 Formation of RNA Pol II elongation complex Reactome Pathway CDK9 protein substrate REACT_6344 Tat-mediated HIV elongation arrest and recovery Reactome Pathway CDK9 protein substrate REACT_22201 Formation of HIV elongation complex in the absence of HIV Tat Reactome Pathway CDK9 protein substrate REACT_833 RNA Polymerase II Transcription Elongation Reactome Pathway CDK9 protein substrate REACT_6346 Formation of HIV-1 elongation complex containing HIV-1 Tat Reactome Pathway CDK9 protein substrate REACT_6162 Tat-mediated elongation of the HIV-1 transcript Reactome Pathway CDK9 protein substrate REACT_120734 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome Pathway STAT5B protein substrate REACT_169118 Signaling by Leptin Reactome Pathway STAT5B protein substrate REACT_17025 Downstream signal transduction Reactome Pathway STAT5B protein substrate REACT_111133 Growth hormone receptor signaling Reactome Pathway STAT5B protein substrate REACT_23837 Interleukin-3, 5 and GM-CSF signaling Reactome Pathway STAT5B protein substrate REACT_115529 Interleukin-7 signaling Reactome Pathway STAT5B protein substrate REACT_27283 Interleukin-2 signaling Reactome Pathway STAT5B protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway STAT5B protein substrate REACT_115697 Prolactin receptor signaling Reactome Pathway STAT5B protein substrate REACT_121141 Signaling by FGFR1 fusion mutants Reactome Pathway RPS6KA3 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway RPS6KA3 protein substrate REACT_20510 RSK activation Reactome Pathway RPS6KA3 protein substrate REACT_12524 CREB phosphorylation Reactome Pathway RPS6KA3 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway RPS6KA3 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway RPS6KA3 protein substrate REACT_120966 Gastrin-CREB signalling pathway via PKC and MAPK Reactome Pathway RPS6KA3 protein substrate REACT_22365 Recycling pathway of L1 Reactome Pathway RPS6KA3 protein substrate REACT_12524 CREB phosphorylation Reactome Pathway RPS6KA3 protein substrate REACT_20568 CREB phosphorylation through the activation of Ras Reactome Pathway JAK3 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway JAK3 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway JAK3 protein substrate REACT_115529 Interleukin-7 signaling Reactome Pathway JAK3 protein substrate REACT_27283 Interleukin-2 signaling Reactome Pathway MAP2K6 protein substrate REACT_22442 Interleukin-1 signaling Reactome Pathway MAP2K6 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAP2K6 protein substrate REACT_21402 CDO in myogenesis Reactome Pathway MAP2K6 protein substrate REACT_21399 activated TAK1 mediates p38 MAPK activation Reactome Pathway MAP2K6 protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway PLK1 protein substrate REACT_1006 Polo-like kinase mediated events Reactome Pathway PLK1 protein substrate REACT_172744 Condensation of Prophase Chromosomes Reactome Pathway PLK1 protein substrate REACT_160122 Activation of NIMA Kinases NEK9, NEK6, NEK7 Reactome Pathway PLK1 protein substrate REACT_15364 Loss of Nlp from mitotic centrosomes Reactome Pathway PLK1 protein substrate REACT_150425 Resolution of Sister Chromatid Cohesion Reactome Pathway PLK1 protein substrate REACT_6761 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Reactome Pathway PLK1 protein substrate REACT_1932 Mitotic Telophase/Cytokinesis Reactome Pathway PLK1 protein substrate REACT_15296 Recruitment of mitotic centrosome proteins and complexes Reactome Pathway PLK1 protein substrate REACT_160315 Regulation of PLK1 Activity at G2/M Transition Reactome Pathway PLK1 protein substrate REACT_1016 Mitotic Metaphase/Anaphase Transition Reactome Pathway PLK1 protein substrate REACT_1857 Cyclin A/B1 associated events during G2/M transition Reactome Pathway PLK1 protein substrate REACT_6875 Phosphorylation of Emi1 Reactome Pathway PLK1 protein substrate REACT_1100 Golgi Cisternae Pericentriolar Stack Reorganization Reactome Pathway PLK1 protein substrate REACT_150471 Separation of Sister Chromatids Reactome Pathway PLK1 protein substrate REACT_6904 Phosphorylation of the APC/C Reactome Pathway PLK1 protein substrate REACT_15451 Loss of proteins required for interphase microtubule organization from the centrosome Reactome Pathway PLK1 protein substrate REACT_682 Mitotic Prometaphase Reactome Pathway ACLY protein substrate REACT_2122 ChREBP activates metabolic gene expression Reactome Pathway ACLY protein substrate REACT_1319 Fatty Acyl-CoA Biosynthesis Reactome Pathway LIMK1 protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway LIMK1 protein substrate REACT_19236 Sema3A PAK dependent Axon repulsion Reactome Pathway LIMK1 protein substrate REACT_19277 Sema4D induced cell migration and growth-cone collapse Reactome Pathway MAPK12 protein substrate REACT_12065 p38MAPK events Reactome Pathway MAPK12 protein substrate REACT_21402 CDO in myogenesis Reactome Pathway MAPK12 protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway MAPK12 protein substrate REACT_25299 DSCAM interactions Reactome Pathway MAPK12 protein substrate REACT_200686 Activation of PPARGC1A (PGC-1alpha) by phosphorylation Reactome Pathway MAPK10 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAPK10 protein substrate REACT_21326 Activation of the AP-1 family of transcription factors Reactome Pathway MAPK10 protein substrate REACT_21368 JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 Reactome Pathway MAPK10 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway VCP protein substrate REACT_200744 HSF1 activation Reactome Pathway CASP9 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway CASP9 protein substrate REACT_607 Activation of caspases through apoptosome-mediated cleavage Reactome Pathway CASP9 protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway CASP9 protein substrate REACT_89 Formation of apoptosome Reactome Pathway CASP9 protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway CASP9 protein substrate REACT_2190 SMAC binds to IAPs Reactome Pathway CASP9 protein substrate REACT_22128 Role of DCC in regulating apoptosis Reactome Pathway CASP9 protein substrate REACT_1767 SMAC-mediated dissociation of IAP:caspase complexes Reactome Pathway BCAR1 protein substrate REACT_17025 Downstream signal transduction Reactome Pathway BCAR1 protein substrate REACT_15381 p130Cas linkage to MAPK signaling for integrins Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_27271 Meiotic recombination Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_172610 HATs acetylate histones Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_172744 Condensation of Prophase Chromosomes Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_2232 RNA Polymerase I Promoter Opening Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_22186 Deposition of new CENPA-containing nucleosomes at the centromere Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_75925 Amyloids Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_7963 Packaging Of Telomere Ends Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_2204 RNA Polymerase I Chain Elongation Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_200827 SIRT1 negatively regulates rRNA Expression Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_200856 NoRC negatively regulates rRNA expression Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_200753 formation of the beta-catenin:TCF transactivating complex Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_75792 Meiotic synapsis Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_200808 PRC2 methylates histones and DNA Reactome Pathway HIST1H4A, HIST1H4B, HIST1H4C, HIST1H4D, HIST1H4E, HIST1H4F, HIST1H4H, HIST1H4I, HIST1H4J, HIST1H4K, HIST1H4L, HIST2H4A, HIST2H4B, HIST4H4 protein substrate REACT_169185 DNA Damage/Telomere Stress Induced Senescence Reactome Pathway GNB1 protein substrate REACT_18274 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Reactome Pathway GNB1 protein substrate REACT_19145 G beta:gamma signalling through PLC beta Reactome Pathway GNB1 protein substrate REACT_1665 Glucagon signaling in metabolic regulation Reactome Pathway GNB1 protein substrate REACT_163932 Activation of the phototransduction cascade Reactome Pathway GNB1 protein substrate REACT_20647 Thromboxane signalling through TP receptor Reactome Pathway GNB1 protein substrate REACT_19327 G alpha (s) signalling events Reactome Pathway GNB1 protein substrate REACT_21384 Thrombin signalling through proteinase activated receptors (PARs) Reactome Pathway GNB1 protein substrate REACT_20653 ADP signalling through P2Y purinoceptor 12 Reactome Pathway GNB1 protein substrate REACT_15457 G-protein activation Reactome Pathway GNB1 protein substrate REACT_24023 Regulation of water balance by renal Aquaporins Reactome Pathway GNB1 protein substrate REACT_163919 Inactivation, recovery and regulation of the phototransduction cascade Reactome Pathway GNB1 protein substrate REACT_18377 Glucagon-type ligand receptors Reactome Pathway GNB1 protein substrate REACT_18283 G alpha (q) signalling events Reactome Pathway GNB1 protein substrate REACT_18407 G alpha (12/13) signalling events Reactome Pathway GNB1 protein substrate REACT_19333 G alpha (z) signalling events Reactome Pathway GNB1 protein substrate REACT_23946 Prostacyclin signalling through prostacyclin receptor Reactome Pathway GNB1 protein substrate REACT_75831 Activation of G protein gated Potassium channels Reactome Pathway GNB1 protein substrate REACT_19290 G beta:gamma signalling through PI3Kgamma Reactome Pathway GNB1 protein substrate REACT_18283 G alpha (q) signalling events Reactome Pathway GNB1 protein substrate REACT_19140 ADP signalling through P2Y purinoceptor 1 Reactome Pathway GNB1 protein substrate REACT_18339 Adrenaline,noradrenaline inhibits insulin secretion Reactome Pathway GNB1 protein substrate REACT_25004 Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits Reactome Pathway GNB1 protein substrate REACT_19231 G alpha (i) signalling events Reactome Pathway GNB1 protein substrate REACT_21254 Presynaptic function of Kainate receptors Reactome Pathway GNB1 protein substrate REACT_172761 Ca2+ pathway Reactome Pathway GNB1 protein substrate REACT_15488 Olfactory Signaling Pathway Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_27271 Meiotic recombination Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_172610 HATs acetylate histones Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_172744 Condensation of Prophase Chromosomes Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_2232 RNA Polymerase I Promoter Opening Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_75925 Amyloids Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_24970 Factors involved in megakaryocyte development and platelet production Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_2204 RNA Polymerase I Chain Elongation Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_200827 SIRT1 negatively regulates rRNA Expression Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_200856 NoRC negatively regulates rRNA expression Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_200753 formation of the beta-catenin:TCF transactivating complex Reactome Pathway HIST1H3A, HIST1H3B, HIST1H3C, HIST1H3D, HIST1H3E, HIST1H3F, HIST1H3G, HIST1H3H, HIST1H3I, HIST1H3J protein substrate REACT_200808 PRC2 methylates histones and DNA Reactome Pathway SIRPA protein substrate REACT_23916 Signal regulatory protein (SIRP) family interactions Reactome Pathway SIRPA protein substrate REACT_12051 Cell surface interactions at the vascular wall Reactome Pathway PRKDC protein substrate REACT_1201 Processing of DNA ends prior to end rejoining Reactome Pathway PRKDC protein substrate REACT_118823 Cytosolic sensors of pathogen-associated DNA Reactome Pathway PRKDC protein substrate REACT_163993 IRF3-mediated induction of type I IFN Reactome Pathway PRKDC protein substrate REACT_1022 Nonhomologous End-joining (NHEJ) Reactome Pathway SMAD3 protein substrate REACT_120850 TGF-beta receptor signaling activates SMADs Reactome Pathway SMAD3 protein substrate REACT_169107 SMAD4 MH2 Domain Mutants in Cancer Reactome Pathway SMAD3 protein substrate REACT_120727 Downregulation of TGF-beta receptor signaling Reactome Pathway SMAD3 protein substrate REACT_111057 Signaling by NODAL Reactome Pathway SMAD3 protein substrate REACT_150238 Signaling by Activin Reactome Pathway SMAD3 protein substrate REACT_169103 SMAD2/3 Phosphorylation Motif Mutants in Cancer Reactome Pathway SMAD3 protein substrate REACT_120734 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome Pathway SMAD3 protein substrate REACT_169165 SMAD2/3 MH2 Domain Mutants in Cancer Reactome Pathway SMAD3 protein substrate REACT_169263 TGFBR1 KD Mutants in Cancer Reactome Pathway SMAD3 protein substrate REACT_121111 Downregulation of SMAD2/3:SMAD4 transcriptional activity Reactome Pathway CDK6 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway CDK6 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway CDK6 protein substrate REACT_169325 Oncogene Induced Senescence Reactome Pathway CDK6 protein substrate REACT_821 Cyclin D associated events in G1 Reactome Pathway MDM2 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway MDM2 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MDM2 protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway MDM2 protein substrate REACT_18307 Trafficking of AMPA receptors Reactome Pathway MDM2 protein substrate REACT_309 Stabilization of p53 Reactome Pathway MDM2 protein substrate REACT_169325 Oncogene Induced Senescence Reactome Pathway KIF23 protein substrate REACT_121399 MHC class II antigen presentation Reactome Pathway KIF23 protein substrate REACT_1932 Mitotic Telophase/Cytokinesis Reactome Pathway KIF23 protein substrate REACT_25201 Kinesins Reactome Pathway MAP2K1 protein substrate REACT_22442 Interleukin-1 signaling Reactome Pathway MAP2K1 protein substrate REACT_1391 ERK1 activation Reactome Pathway MAP2K1 protein substrate REACT_1391 ERK1 activation Reactome Pathway MAP2K1 protein substrate REACT_9470 Signaling by FGFR Reactome Pathway MAP2K1 protein substrate REACT_962 MEK activation Reactome Pathway MAP2K1 protein substrate REACT_614 RAF phosphorylates MEK Reactome Pathway MAP2K1 protein substrate REACT_22272 Signal transduction by L1 Reactome Pathway TEK protein substrate REACT_12621 Tie2 Signaling Reactome Pathway FKBP4 protein substrate REACT_200624 Attenuation phase Reactome Pathway CAV1 protein substrate REACT_12541 NOSTRIN mediated eNOS trafficking Reactome Pathway CAV1 protein substrate REACT_494 Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis Reactome Pathway CAV1 protein substrate REACT_12560 Basigin interactions Reactome Pathway CAV1 protein substrate REACT_12477 eNOS activation Reactome Pathway RELA protein substrate REACT_27161 Transcriptional regulation of white adipocyte differentiation Reactome Pathway RELA protein substrate REACT_118563 RIP-mediated NFkB activation via ZBP1 Reactome Pathway RELA protein substrate REACT_13443 Regulated proteolysis of p75NTR Reactome Pathway RELA protein substrate REACT_12555 Downstream TCR signaling Reactome Pathway RELA protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway RELA protein substrate REACT_163994 FCERI mediated NF-kB activation Reactome Pathway RELA protein substrate REACT_13696 NF-kB is activated and signals survival Reactome Pathway RELA protein substrate REACT_21281 TAK1 activates NFkB by phosphorylation and activation of IKKs complex Reactome Pathway RELA protein substrate REACT_118656 Activation of NF-kappaB in B cells Reactome Pathway RELA protein substrate REACT_24969 TRAF6 mediated NF-kB activation Reactome Pathway RELA protein substrate REACT_163773 DEx/H-box helicases activate type I IFN and inflammatory cytokines production Reactome Pathway RELA protein substrate REACT_23950 Interleukin-1 processing Reactome Pathway DNM1 protein substrate REACT_11035 Gap junction degradation Reactome Pathway DNM1 protein substrate REACT_121399 MHC class II antigen presentation Reactome Pathway DNM1 protein substrate REACT_12435 Retrograde neurotrophin signalling Reactome Pathway DNM1 protein substrate REACT_11049 Formation of annular gap junctions Reactome Pathway DNM1 protein substrate REACT_6894 Toll Like Receptor 4 (TLR4) Cascade Reactome Pathway DNM1 protein substrate REACT_22365 Recycling pathway of L1 Reactome Pathway GAD2 protein substrate REACT_24020 GABA synthesis Reactome Pathway GAD2 protein substrate REACT_23947 GABA synthesis, release, reuptake and degradation Reactome Pathway PTK2 protein substrate REACT_23916 Signal regulatory protein (SIRP) family interactions Reactome Pathway PTK2 protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway PTK2 protein substrate REACT_15523 Integrin alphaIIb beta3 signaling Reactome Pathway PTK2 protein substrate REACT_107 Apoptotic cleavage of cellular proteins Reactome Pathway PTK2 protein substrate REACT_22351 DCC mediated attractive signaling Reactome Pathway PTK2 protein substrate REACT_15443 GRB2:SOS provides linkage to MAPK signaling for Integrins Reactome Pathway PTK2 protein substrate REACT_22384 Netrin mediated repulsion signals Reactome Pathway PTK2 protein substrate REACT_15381 p130Cas linkage to MAPK signaling for integrins Reactome Pathway PTK2 protein substrate REACT_18334 NCAM signaling for neurite out-growth Reactome Pathway PRKCD protein substrate REACT_160158 Role of phospholipids in phagocytosis Reactome Pathway PRKCD protein substrate REACT_111064 DAG and IP3 signaling Reactome Pathway PRKCD protein substrate REACT_19333 G alpha (z) signalling events Reactome Pathway PRKCD protein substrate REACT_107 Apoptotic cleavage of cellular proteins Reactome Pathway PRKCD protein substrate REACT_2202 Effects of PIP2 hydrolysis Reactome Pathway PRKCD protein substrate REACT_9000 Calmodulin induced events Reactome Pathway PRKCD protein substrate REACT_25078 Interferon gamma signaling Reactome Pathway PRKCD protein substrate REACT_9000 Calmodulin induced events Reactome Pathway PRKCD protein substrate REACT_25218 HuR stabilizes mRNA Reactome Pathway TJP1 protein substrate REACT_13579 Apoptotic cleavage of cell adhesion proteins Reactome Pathway TJP1 protein substrate REACT_11043 c-src mediated regulation of Cx43 function and closure of gap junctions Reactome Pathway TJP1 protein substrate REACT_118607 Signaling by Hippo Reactome Pathway BAX protein substrate REACT_584 Activation, translocation and oligomerization of BAX Reactome Pathway GOLGA2 protein substrate REACT_1100 Golgi Cisternae Pericentriolar Stack Reorganization Reactome Pathway ARHGAP5 protein substrate REACT_11051 Rho GTPase cycle Reactome Pathway STK4 protein substrate REACT_118607 Signaling by Hippo Reactome Pathway PRKAA1 protein substrate REACT_21393 Regulation of Rheb GTPase activity by AMPK Reactome Pathway PRKAA1 protein substrate REACT_21285 Regulation of AMPK activity via LKB1 Reactome Pathway PAK1 protein substrate REACT_160086 Regulation of actin dynamics for phagocytic cup formation Reactome Pathway PAK1 protein substrate REACT_19236 Sema3A PAK dependent Axon repulsion Reactome Pathway PAK1 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway PAK1 protein substrate REACT_19226 Activation of Rac Reactome Pathway PAK1 protein substrate REACT_19238 CD28 dependent Vav1 pathway Reactome Pathway PAK1 protein substrate REACT_12623 Generation of second messenger molecules Reactome Pathway PAK1 protein substrate REACT_25299 DSCAM interactions Reactome Pathway PAK1 protein substrate REACT_22272 Signal transduction by L1 Reactome Pathway MAPK7 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway MAPK7 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway MAPK7 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway MAPK7 protein substrate REACT_12436 ERKs are inactivated Reactome Pathway MAPK7 protein substrate REACT_12436 ERKs are inactivated Reactome Pathway MAPK7 protein substrate REACT_120966 Gastrin-CREB signalling pathway via PKC and MAPK Reactome Pathway MAPK7 protein substrate REACT_12020 Signalling to ERK5 Reactome Pathway PAK2 protein substrate REACT_13532 Stimulation of the cell death response by PAK-2p34 Reactome Pathway PAK2 protein substrate REACT_19236 Sema3A PAK dependent Axon repulsion Reactome Pathway PAK2 protein substrate REACT_163701 FCERI mediated MAPK activation Reactome Pathway PAK2 protein substrate REACT_19226 Activation of Rac Reactome Pathway PAK2 protein substrate REACT_19238 CD28 dependent Vav1 pathway Reactome Pathway PAK2 protein substrate REACT_13528 Regulation of PAK-2p34 activity by PS-GAP/RHG10 Reactome Pathway PAK2 protein substrate REACT_11068 Nef and signal transduction Reactome Pathway PAK2 protein substrate REACT_12623 Generation of second messenger molecules Reactome Pathway PAK2 protein substrate REACT_13464 Regulation of activated PAK-2p34 by proteasome mediated degradation Reactome Pathway SKP2 protein substrate REACT_75842 Antigen processing: Ubiquitination & Proteasome degradation Reactome Pathway SKP2 protein substrate REACT_6761 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Reactome Pathway SKP2 protein substrate REACT_9003 SCF(Skp2)-mediated degradation of p27/p21 Reactome Pathway SKP2 protein substrate REACT_821 Cyclin D associated events in G1 Reactome Pathway SKP2 protein substrate REACT_9003 SCF(Skp2)-mediated degradation of p27/p21 Reactome Pathway ATM protein substrate REACT_27271 Meiotic recombination Reactome Pathway ATM protein substrate REACT_97 Recruitment of repair and signaling proteins to double-strand breaks Reactome Pathway ATM protein substrate REACT_897 G2/M DNA damage checkpoint Reactome Pathway ATM protein substrate REACT_200780 Regulation of HSF1-mediated heat shock response Reactome Pathway ATM protein substrate REACT_204 ATM mediated response to DNA double-strand break Reactome Pathway ATM protein substrate REACT_1924 ATM mediated phosphorylation of repair proteins Reactome Pathway ATM protein substrate REACT_309 Stabilization of p53 Reactome Pathway ATM protein substrate REACT_1614 Ubiquitin Mediated Degradation of Phosphorylated Cdc25A Reactome Pathway ATM protein substrate REACT_20549 Autodegradation of the E3 ubiquitin ligase COP1 Reactome Pathway ATM protein substrate REACT_169185 DNA Damage/Telomere Stress Induced Senescence Reactome Pathway ATM protein substrate REACT_18265 Regulation of the Fanconi anemia pathway Reactome Pathway NFATC2 protein substrate REACT_163834 FCERI mediated Ca+2 mobilization Reactome Pathway GAB1 protein substrate REACT_121398 Signaling by FGFR mutants Reactome Pathway GAB1 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway GAB1 protein substrate REACT_976 PI3K Cascade Reactome Pathway GAB1 protein substrate REACT_976 PI3K Cascade Reactome Pathway GAB1 protein substrate REACT_115852 Signaling by constitutively active EGFR Reactome Pathway GAB1 protein substrate REACT_21270 PI-3K cascade Reactome Pathway GAB1 protein substrate REACT_116008 PI3K events in ERBB2 signaling Reactome Pathway GAB1 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway GAB1 protein substrate REACT_12578 GAB1 signalosome Reactome Pathway CAMK2B protein substrate REACT_18307 Trafficking of AMPA receptors Reactome Pathway CAMK2B protein substrate REACT_20546 Ras activation uopn Ca2+ infux through NMDA receptor Reactome Pathway CAMK2B protein substrate REACT_20594 Unblocking of NMDA receptor, glutamate binding and activation Reactome Pathway CAMK2B protein substrate REACT_20642 CREB phosphorylation through the activation of CaMKII Reactome Pathway CAMK2B protein substrate REACT_200775 HSF1-dependent transactivation Reactome Pathway CAMK2B protein substrate REACT_25078 Interferon gamma signaling Reactome Pathway CAMK2B protein substrate REACT_20568 CREB phosphorylation through the activation of Ras Reactome Pathway CAMK2G protein substrate REACT_18307 Trafficking of AMPA receptors Reactome Pathway CAMK2G protein substrate REACT_20546 Ras activation uopn Ca2+ infux through NMDA receptor Reactome Pathway CAMK2G protein substrate REACT_20594 Unblocking of NMDA receptor, glutamate binding and activation Reactome Pathway CAMK2G protein substrate REACT_20642 CREB phosphorylation through the activation of CaMKII Reactome Pathway CAMK2G protein substrate REACT_200775 HSF1-dependent transactivation Reactome Pathway CAMK2G protein substrate REACT_25078 Interferon gamma signaling Reactome Pathway CAMK2G protein substrate REACT_20568 CREB phosphorylation through the activation of Ras Reactome Pathway PRKG1 protein substrate REACT_172761 Ca2+ pathway Reactome Pathway PTK2B protein substrate REACT_23916 Signal regulatory protein (SIRP) family interactions Reactome Pathway PTK2B protein substrate REACT_27283 Interleukin-2 signaling Reactome Pathway KCNB1 protein substrate REACT_75770 Voltage gated Potassium channels Reactome Pathway KCNB1 protein substrate REACT_18274 Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Reactome Pathway CASP8 protein substrate REACT_1503 Caspase-8 activation Reactome Pathway CASP8 protein substrate REACT_13541 Caspase-mediated cleavage of cytoskeletal proteins Reactome Pathway CASP8 protein substrate REACT_900 FasL/ CD95L signaling Reactome Pathway CASP8 protein substrate REACT_995 Apoptotic execution phase Reactome Pathway CASP8 protein substrate REACT_402 TRAIL signaling Reactome Pathway CASP8 protein substrate REACT_107 Apoptotic cleavage of cellular proteins Reactome Pathway CASP8 protein substrate REACT_150361 TRIF-mediated programmed cell death Reactome Pathway CASP8 protein substrate REACT_25039 NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10 Reactome Pathway CASP8 protein substrate REACT_832 Dimerization of procaspase-8 Reactome Pathway CASP8 protein substrate REACT_1432 TNF signaling Reactome Pathway CASP8 protein substrate REACT_164011 Regulation by c-FLIP Reactome Pathway CASP8 protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway CASP8 protein substrate REACT_701 Activation, myristolyation of BID and translocation to mitochondria Reactome Pathway GRM3 protein substrate REACT_19231 G alpha (i) signalling events Reactome Pathway GRM3 protein substrate REACT_18319 Class C/3 (Metabotropic glutamate/pheromone receptors) Reactome Pathway SLC10A1 protein substrate REACT_11042 Recycling of bile acids and salts Reactome Pathway POLD3 protein substrate REACT_70 Removal of the Flap Intermediate Reactome Pathway POLD3 protein substrate REACT_1385 Processive synthesis on the lagging strand Reactome Pathway POLD3 protein substrate REACT_1993 Repair synthesis for gap-filling by DNA polymerase in TC-NER Reactome Pathway POLD3 protein substrate REACT_7961 Telomere C-strand (Lagging Strand) Synthesis Reactome Pathway POLD3 protein substrate REACT_8027 Processive synthesis on the C-strand of the telomere Reactome Pathway POLD3 protein substrate REACT_378 Repair synthesis of patch ~27-30 bases long by DNA polymerase Reactome Pathway POLD3 protein substrate REACT_7987 Polymerase switching on the C-strand of the telomere Reactome Pathway POLD3 protein substrate REACT_1792 Polymerase switching Reactome Pathway POLD3 protein substrate REACT_7999 Removal of the Flap Intermediate from the C-strand Reactome Pathway POLD3 protein substrate REACT_2192 Removal of DNA patch containing abasic residue Reactome Pathway POLD3 protein substrate REACT_1838 Leading Strand Synthesis Reactome Pathway POLD3 protein substrate REACT_1128 Resolution of AP sites via the multiple-nucleotide patch replacement pathway Reactome Pathway CDK5R1 protein substrate REACT_19199 CRMPs in Sema3A signaling Reactome Pathway PRKD1 protein substrate REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway PPP2R5A protein substrate REACT_200610 disassembly of the destruction complex and recruitment of AXIN to the membrane Reactome Pathway PPP2R5A protein substrate REACT_11063 Degradation of beta-catenin by the destruction complex Reactome Pathway PPP2R5A protein substrate REACT_11065 Beta-catenin phosphorylation cascade Reactome Pathway PPP2R5A protein substrate REACT_150425 Resolution of Sister Chromatid Cohesion Reactome Pathway PPP2R5A protein substrate REACT_150471 Separation of Sister Chromatids Reactome Pathway PPP2R5A protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway PPP2R5A protein substrate REACT_23879 Platelet sensitization by LDL Reactome Pathway PPP2R5A protein substrate REACT_682 Mitotic Prometaphase Reactome Pathway ERBB4 protein substrate REACT_116005 SHC1 events in ERBB4 signaling Reactome Pathway ERBB4 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway ERBB4 protein substrate REACT_116022 Nuclear signaling by ERBB4 Reactome Pathway ERBB4 protein substrate REACT_115596 Signaling by ERBB4 Reactome Pathway ERBB4 protein substrate REACT_115854 GRB2 events in ERBB2 signaling Reactome Pathway ERBB4 protein substrate REACT_116008 PI3K events in ERBB2 signaling Reactome Pathway ERBB4 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway ERBB4 protein substrate REACT_115961 PI3K events in ERBB4 signaling Reactome Pathway ERBB4 protein substrate REACT_115828 Downregulation of ERBB4 signaling Reactome Pathway ERBB4 protein substrate REACT_115993 SHC1 events in ERBB2 signaling Reactome Pathway ERBB4 protein substrate REACT_115755 Signaling by ERBB2 Reactome Pathway RPS6KA1 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway RPS6KA1 protein substrate REACT_20510 RSK activation Reactome Pathway RPS6KA1 protein substrate REACT_12524 CREB phosphorylation Reactome Pathway RPS6KA1 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway RPS6KA1 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway RPS6KA1 protein substrate REACT_120966 Gastrin-CREB signalling pathway via PKC and MAPK Reactome Pathway RPS6KA1 protein substrate REACT_22365 Recycling pathway of L1 Reactome Pathway RPS6KA1 protein substrate REACT_12524 CREB phosphorylation Reactome Pathway RPS6KA1 protein substrate REACT_20568 CREB phosphorylation through the activation of Ras Reactome Pathway SMAD2 protein substrate REACT_120850 TGF-beta receptor signaling activates SMADs Reactome Pathway SMAD2 protein substrate REACT_169107 SMAD4 MH2 Domain Mutants in Cancer Reactome Pathway SMAD2 protein substrate REACT_120727 Downregulation of TGF-beta receptor signaling Reactome Pathway SMAD2 protein substrate REACT_111057 Signaling by NODAL Reactome Pathway SMAD2 protein substrate REACT_150238 Signaling by Activin Reactome Pathway SMAD2 protein substrate REACT_169103 SMAD2/3 Phosphorylation Motif Mutants in Cancer Reactome Pathway SMAD2 protein substrate REACT_120734 SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Reactome Pathway SMAD2 protein substrate REACT_169165 SMAD2/3 MH2 Domain Mutants in Cancer Reactome Pathway SMAD2 protein substrate REACT_169263 TGFBR1 KD Mutants in Cancer Reactome Pathway SMAD2 protein substrate REACT_121111 Downregulation of SMAD2/3:SMAD4 transcriptional activity Reactome Pathway SMAD1 protein substrate REACT_12034 Signaling by BMP Reactome Pathway MAPK14 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway MAPK14 protein substrate REACT_21326 Activation of the AP-1 family of transcription factors Reactome Pathway MAPK14 protein substrate REACT_25042 KSRP destabilizes mRNA Reactome Pathway MAPK14 protein substrate REACT_23879 Platelet sensitization by LDL Reactome Pathway MAPK14 protein substrate REACT_25299 DSCAM interactions Reactome Pathway MAPK14 protein substrate REACT_200686 Activation of PPARGC1A (PGC-1alpha) by phosphorylation Reactome Pathway MAPK14 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway MAPK14 protein substrate REACT_19140 ADP signalling through P2Y purinoceptor 1 Reactome Pathway MAPK14 protein substrate REACT_12065 p38MAPK events Reactome Pathway MAPK14 protein substrate REACT_12599 ERK/MAPK targets Reactome Pathway MAPK14 protein substrate REACT_21402 CDO in myogenesis Reactome Pathway MAPK14 protein substrate REACT_21399 activated TAK1 mediates p38 MAPK activation Reactome Pathway MAPK14 protein substrate REACT_75776 NOD1/2 Signaling Pathway Reactome Pathway CDC37 protein substrate REACT_115852 Signaling by constitutively active EGFR Reactome Pathway CDC37 protein substrate REACT_115755 Signaling by ERBB2 Reactome Pathway CAMK4 protein substrate REACT_20661 CREB phosphorylation through the activation of CaMKK Reactome Pathway CAMK4 protein substrate REACT_200608 Transcriptional activation of mitochondrial biogenesis Reactome Pathway CAMK4 protein substrate REACT_20652 Activation of CaMK IV Reactome Pathway CAMK4 protein substrate REACT_15502 CaMK IV-mediated phosphorylation of CREB Reactome Pathway CAMK4 protein substrate REACT_15502 CaMK IV-mediated phosphorylation of CREB Reactome Pathway BAK1 protein substrate REACT_707 Activation and oligomerization of BAK protein Reactome Pathway OCLN protein substrate REACT_13579 Apoptotic cleavage of cell adhesion proteins Reactome Pathway SMN1, SMN2 protein substrate REACT_11066 snRNP Assembly Reactome Pathway PACS1 protein substrate REACT_11103 Nef mediated downregulation of MHC class I complex cell surface expression Reactome Pathway PARD3 protein substrate REACT_120726 TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) Reactome Pathway PARD3 protein substrate REACT_19373 Tight junction interactions Reactome Pathway HDAC7 protein substrate REACT_160254 Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Reactome Pathway HDAC7 protein substrate REACT_118780 NOTCH1 Intracellular Domain Regulates Transcription Reactome Pathway HDAC7 protein substrate REACT_160243 Constitutive Signaling by NOTCH1 PEST Domain Mutants Reactome Pathway KIFAP3 protein substrate REACT_121399 MHC class II antigen presentation Reactome Pathway KIFAP3 protein substrate REACT_147867 Translocation of GLUT4 to the plasma membrane Reactome Pathway KIFAP3 protein substrate REACT_25201 Kinesins Reactome Pathway BAD protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway BAD protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway BAD protein substrate REACT_13638 NRAGE signals death through JNK Reactome Pathway BAD protein substrate REACT_330 BH3-only proteins associate with and inactivate anti-apoptotic BCL-2 members Reactome Pathway BAD protein substrate REACT_549 Activation of BAD and translocation to mitochondria Reactome Pathway GAD1 protein substrate REACT_24020 GABA synthesis Reactome Pathway GAD1 protein substrate REACT_23947 GABA synthesis, release, reuptake and degradation Reactome Pathway MAP3K5 protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway DOK1 protein substrate REACT_976 PI3K Cascade Reactome Pathway DOK1 protein substrate REACT_976 PI3K Cascade Reactome Pathway DOK1 protein substrate REACT_508 Signal attenuation Reactome Pathway DOK1 protein substrate REACT_570 IRS activation Reactome Pathway SMO protein substrate REACT_18372 Class B/2 (Secretin family receptors) Reactome Pathway HIST1H2BM protein substrate REACT_27271 Meiotic recombination Reactome Pathway HIST1H2BM protein substrate REACT_169436 Oxidative Stress Induced Senescence Reactome Pathway HIST1H2BM protein substrate REACT_172610 HATs acetylate histones Reactome Pathway HIST1H2BM protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway HIST1H2BM protein substrate REACT_172744 Condensation of Prophase Chromosomes Reactome Pathway HIST1H2BM protein substrate REACT_2232 RNA Polymerase I Promoter Opening Reactome Pathway HIST1H2BM protein substrate REACT_22186 Deposition of new CENPA-containing nucleosomes at the centromere Reactome Pathway HIST1H2BM protein substrate REACT_75925 Amyloids Reactome Pathway HIST1H2BM protein substrate REACT_7963 Packaging Of Telomere Ends Reactome Pathway HIST1H2BM protein substrate REACT_2204 RNA Polymerase I Chain Elongation Reactome Pathway HIST1H2BM protein substrate REACT_200827 SIRT1 negatively regulates rRNA Expression Reactome Pathway HIST1H2BM protein substrate REACT_200856 NoRC negatively regulates rRNA expression Reactome Pathway HIST1H2BM protein substrate REACT_200753 formation of the beta-catenin:TCF transactivating complex Reactome Pathway HIST1H2BM protein substrate REACT_75792 Meiotic synapsis Reactome Pathway HIST1H2BM protein substrate REACT_200808 PRC2 methylates histones and DNA Reactome Pathway HIST1H2BM protein substrate REACT_169185 DNA Damage/Telomere Stress Induced Senescence Reactome Pathway CEP250 protein substrate REACT_160315 Regulation of PLK1 Activity at G2/M Transition Reactome Pathway CEP250 protein substrate REACT_15364 Loss of Nlp from mitotic centrosomes Reactome Pathway CEP250 protein substrate REACT_15296 Recruitment of mitotic centrosome proteins and complexes Reactome Pathway CEP250 protein substrate REACT_15451 Loss of proteins required for interphase microtubule organization from the centrosome Reactome Pathway CARD11 protein substrate REACT_12555 Downstream TCR signaling Reactome Pathway CARD11 protein substrate REACT_163994 FCERI mediated NF-kB activation Reactome Pathway CARD11 protein substrate REACT_118656 Activation of NF-kappaB in B cells Reactome Pathway NDEL1 protein substrate REACT_150425 Resolution of Sister Chromatid Cohesion Reactome Pathway NDEL1 protein substrate REACT_150471 Separation of Sister Chromatids Reactome Pathway NDEL1 protein substrate REACT_682 Mitotic Prometaphase Reactome Pathway RACGAP1 protein substrate REACT_121399 MHC class II antigen presentation Reactome Pathway RACGAP1 protein substrate REACT_11051 Rho GTPase cycle Reactome Pathway RACGAP1 protein substrate REACT_25201 Kinesins Reactome Pathway TRPV6 protein substrate REACT_169333 TRP channels Reactome Pathway SETD8 protein substrate REACT_172744 Condensation of Prophase Chromosomes Reactome Pathway INCENP protein substrate REACT_150425 Resolution of Sister Chromatid Cohesion Reactome Pathway INCENP protein substrate REACT_150471 Separation of Sister Chromatids Reactome Pathway INCENP protein substrate REACT_682 Mitotic Prometaphase Reactome Pathway GRLF1 protein substrate REACT_19266 Sema4D mediated inhibition of cell attachment and migration Reactome Pathway GRLF1 protein substrate REACT_11051 Rho GTPase cycle Reactome Pathway SPHK1 protein substrate REACT_16907 Association of TriC/CCT with target proteins during biosynthesis Reactome Pathway SPHK1 protein substrate REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway PPP1R1B protein substrate REACT_15334 DARPP-32 events Reactome Pathway DDX20 protein substrate REACT_11066 snRNP Assembly Reactome Pathway FZR1 protein substrate REACT_6867 Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase Reactome Pathway FZR1 protein substrate REACT_75842 Antigen processing: Ubiquitination & Proteasome degradation Reactome Pathway FZR1 protein substrate REACT_6785 Autodegradation of Cdh1 by Cdh1:APC/C Reactome Pathway FZR1 protein substrate REACT_6821 SCF-beta-TrCP mediated degradation of Emi1 Reactome Pathway FZR1 protein substrate REACT_169168 Senescence-Associated Secretory Phenotype (SASP) Reactome Pathway FZR1 protein substrate REACT_6875 Phosphorylation of Emi1 Reactome Pathway FZR1 protein substrate REACT_1156 Orc1 removal from chromatin Reactome Pathway FZR1 protein substrate REACT_6761 APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 Reactome Pathway FZR1 protein substrate REACT_1156 Orc1 removal from chromatin Reactome Pathway FZR1 protein substrate REACT_9029 Cyclin A:Cdk2-associated events at S phase entry Reactome Pathway FZR1 protein substrate REACT_6837 Regulation of APC/C activators between G1/S and early anaphase Reactome Pathway GAB2 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway GAB2 protein substrate REACT_23891 Interleukin receptor SHC signaling Reactome Pathway GAB2 protein substrate REACT_111040 Signaling by SCF-KIT Reactome Pathway GAB2 protein substrate REACT_121141 Signaling by FGFR1 fusion mutants Reactome Pathway GAB2 protein substrate REACT_163769 Role of LAT2/NTAL/LAB on calcium mobilization Reactome Pathway CAMK2A protein substrate REACT_18307 Trafficking of AMPA receptors Reactome Pathway CAMK2A protein substrate REACT_20546 Ras activation uopn Ca2+ infux through NMDA receptor Reactome Pathway CAMK2A protein substrate REACT_20594 Unblocking of NMDA receptor, glutamate binding and activation Reactome Pathway CAMK2A protein substrate REACT_20642 CREB phosphorylation through the activation of CaMKII Reactome Pathway CAMK2A protein substrate REACT_200775 HSF1-dependent transactivation Reactome Pathway CAMK2A protein substrate REACT_25078 Interferon gamma signaling Reactome Pathway CAMK2A protein substrate REACT_20568 CREB phosphorylation through the activation of Ras Reactome Pathway CAMK2A protein substrate REACT_172761 Ca2+ pathway Reactome Pathway AKT3 protein substrate REACT_147727 Constitutive PI3K/AKT Signaling in Cancer Reactome Pathway AKT3 protein substrate REACT_115662 Downregulation of ERBB2:ERBB3 signaling Reactome Pathway AKT3 protein substrate REACT_12564 AKT phosphorylates targets in the cytosol Reactome Pathway AKT3 protein substrate REACT_12447 Negative regulation of the PI3K/AKT network Reactome Pathway AKT3 protein substrate REACT_1695 GPVI-mediated activation cascade Reactome Pathway AKT3 protein substrate REACT_13655 AKT-mediated inactivation of FOXO1A Reactome Pathway AKT3 protein substrate REACT_19405 CTLA4 inhibitory signaling Reactome Pathway AKT3 protein substrate REACT_12442 AKT phosphorylates targets in the nucleus Reactome Pathway AKT3 protein substrate REACT_19290 G beta:gamma signalling through PI3Kgamma Reactome Pathway AKT3 protein substrate REACT_75829 PIP3 activates AKT signaling Reactome Pathway AKT3 protein substrate REACT_19358 CD28 dependent PI3K/Akt signaling Reactome Pathway AKT3 protein substrate REACT_549 Activation of BAD and translocation to mitochondria Reactome Pathway COL4A3BP protein substrate REACT_115810 Sphingolipid de novo biosynthesis Reactome Pathway STK3 protein substrate REACT_118607 Signaling by Hippo Reactome Pathway TRAF2 protein substrate REACT_1432 TNF signaling Reactome Pathway TRAF2 protein substrate REACT_1503 Caspase-8 activation Reactome Pathway TRAF2 protein substrate REACT_24969 TRAF6 mediated NF-kB activation Reactome Pathway TRAF2 protein substrate REACT_164011 Regulation by c-FLIP Reactome Pathway TRAF2 protein substrate REACT_24938 TRAF6 mediated IRF7 activation Reactome Pathway TRAF2 protein substrate REACT_832 Dimerization of procaspase-8 Reactome Pathway BMPR2 protein substrate REACT_12034 Signaling by BMP Reactome Pathway SPRY2 protein substrate REACT_12484 EGFR downregulation Reactome Pathway SPRY2 protein substrate REACT_111080 Spry regulation of FGF signaling Reactome Pathway NTRK2 protein substrate REACT_11046 NGF-independant TRKA activation Reactome Pathway PAG1 protein substrate REACT_12582 Phosphorylation of CD3 and TCR zeta chains Reactome Pathway PAG1 protein substrate REACT_12578 GAB1 signalosome Reactome Pathway GYS1 protein substrate REACT_169208 Glycogen synthesis Reactome Pathway GYS1 protein substrate REACT_200783 Myoclonic epilepsy of Lafora Reactome Pathway CD36 protein substrate REACT_27161 Transcriptional regulation of white adipocyte differentiation Reactome Pathway CD36 protein substrate REACT_318 Platelet degranulation Reactome Pathway CD36 protein substrate REACT_116145 PPARA activates gene expression Reactome Pathway CD36 protein substrate REACT_111174 Cross-presentation of particulate exogenous antigens (phagosomes) Reactome Pathway CD36 protein substrate REACT_8006 Toll Like Receptor TLR6:TLR2 Cascade Reactome Pathway CD36 protein substrate REACT_6788 MyD88:Mal cascade initiated on plasma membrane Reactome Pathway CD36 protein substrate REACT_163679 Scavenging by Class B Receptors Reactome Pathway LMNB1 protein substrate REACT_200828 Depolymerisation of the Nuclear Lamina Reactome Pathway LMNB1 protein substrate REACT_160251 Clearance of Nuclear Envelope Membranes from Chromatin Reactome Pathway LMNB1 protein substrate REACT_13472 Breakdown of the nuclear lamina Reactome Pathway LMNB1 protein substrate REACT_160242 Initiation of Nuclear Envelope Reformation Reactome Pathway LMNB1 protein substrate REACT_75792 Meiotic synapsis Reactome Pathway LMNB1 protein substrate REACT_169121 Formation of Senescence-Associated Heterochromatin Foci (SAHF) Reactome Pathway